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Tytuł:
Youth and Cancer Prevention (with the Example of Cervical Cancer)
Autorzy:
Świątkiewicz-Mośny, Maria
Powiązania:
https://bibliotekanauki.pl/articles/1997547.pdf
Data publikacji:
2017-12-31
Wydawca:
Wydawnictwo Adam Marszałek
Tematy:
youth
cancer prevention
cervical cancer
Opis:
The research results presented in this article originate from the research and educational project conducted from January to June 2017, titled Prevention of cervical carcinoma, or how it is done in Tychy. Analysis of knowledge sources and the views on HPV vaccines, which was funded with a grant by the Polish Cancer League Foundation. The research material allowed for formulating the guidelines for the educational and preventive treatment programs addressed to young people and their parents. Despite free vaccinations against the HPV virus from some local governments, the percentage of people covered by vaccinations is decreasing. What is needed in order to reverse the negative tendencies is a set of new, innovative solutions, addressed at the needs and expectations of the beneficiaries. Therefore, people should be educated on the risk of falling ill, while HPV vaccinations constitute an important element of primary prevention.
Źródło:
The New Educational Review; 2017, 50; 83-93
1732-6729
Pojawia się w:
The New Educational Review
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Improving cancer outcomes through better cancer data in Poland
Autorzy:
Gralinska, Margaret
Nawrocki, Sergiusz
Powiązania:
https://bibliotekanauki.pl/articles/1065994.pdf
Data publikacji:
2013
Wydawca:
Medical Education
Tematy:
NFZ
cancer
cancer data strategy
evidence based health policy
Opis:
Based on NFZ published aggregate data, the public spending on cancer care in Poland was 6.3 billion PLN in 2011 (or approximately 10% of total public health spending). Poland is one of the few large countries in the world that has two centralised and public data sources for cancer, namely the National Cancer Registry (NCR, pol. Krajowy Rejestr Nowotworów – KRN) and activity expenditure database run by the National Health Fund (NFZ, pol. Narodowy Fundusz Zdrowia). We show in our article that having a population-based registry and a complete treatment/clinical care dataset is a necessary condition to have a useful cancer strategy data set that can in turn lead to evidence based health policies in the area of cancer. Lack of audited and publicly available cancer data means that a coherent cancer strategy, assessing service provision and cost effectiveness of treatments and monitoring outcomes is, in our opinion, currently not possible in Poland. We postulate that Poland should create a task force to create cancer data strategy based on NCIN (National Cancer Intelligence Network) in the UK or Cancer Australia.
Źródło:
OncoReview; 2013, 3, 3; 177-190
2450-6125
Pojawia się w:
OncoReview
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Knowledge and Awareness of Colorectal Cancer
Autorzy:
Lewandowski, Miłosz
Lipiński, Przemysław
Bednarski, Igor
Mik, Michał
Dziki, Adam
Powiązania:
https://bibliotekanauki.pl/articles/1391790.pdf
Data publikacji:
2020
Wydawca:
Index Copernicus International
Tematy:
awareness
colon cancer
colonoscopy
colorectal cancer
rectal cancer
stomy
Opis:
Introduction: Colorectal cancer (CRC) is the third most common malignancy in men and the second most common in women. The disease constitutes a significant civilization and social problem. The aim: The aim of the study is to assess the sudy group’s awareness and knowledge about CRC, as well as about its diagnostics and treatment. Material and methods: An online questionaire form was distributed in the study group regarding issues related to CRC, and followed by statistical analysis and interpretation of the obtained survey results. Results: After analysis, we found that a significant percentage of the surveyed sample group had basic knowledge and awareness in the area of CRC, whereas about half of the respondents did not consider themselves sufficiently informed about the disease. Conclusions: Considering the scale of the problem posed by CRC, it is necessary to undertake broader action to promote knowledge about this disease and to carry out this type of research on a larger and more socioeconomically diverse population.
Źródło:
Polish Journal of Surgery; 2020, 92, 2; 34-41
0032-373X
2299-2847
Pojawia się w:
Polish Journal of Surgery
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Overdiagnosis of Thyroid Cancer
Autorzy:
Machała, Ewa
Powiązania:
https://bibliotekanauki.pl/articles/1177715.pdf
Data publikacji:
2018
Wydawca:
Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
Tematy:
fine needle aspiration biopsy
overdiagnosis
papillary thyroid cancer
throidectomy
thyroid cancer
Opis:
Overdiagnosis of thyroid cancers contributes to increased incidence of thyroid cancers worldwide, which is already a serious public health problem. A great number of medical tests, helping to detect thyroid cancer, may result in an epidemic of diagnosis. A dramatic increase in the number of detected cases of thyroid cancer may be associated with a great number of neck ultrasounds, fine- needle aspirations and incidental findings during examination. Unfortunately, in response to overdiagnosis, more and more surgeries are being performed. It is important to differentiate stationary cancers from potentially aggressive diseases. Detection of cancer contributes to saving lives. However, in some instances it can be harmful, particularly if the disease is overdiagnosed. The aim of this review is to give a balanced view of thyroid cancer epidemic and controversies arising out of overdiagnosis.
Źródło:
World Scientific News; 2018, 101; 120-131
2392-2192
Pojawia się w:
World Scientific News
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Biomineralogy of cancer
Autorzy:
Pawlikowski, M.
Powiązania:
https://bibliotekanauki.pl/articles/344033.pdf
Data publikacji:
2018
Wydawca:
nakł. Maciej Pawlikowski
Tematy:
biomineralogia
rak
biomineralogy
cancer
Źródło:
Auxiliary Sciences in Archaeology, Preservation of Relics and Environmental Engineering; 2018, 25; 66-70
1689-6742
Pojawia się w:
Auxiliary Sciences in Archaeology, Preservation of Relics and Environmental Engineering
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Nutritional assessment of selected patients with cancer
Autorzy:
Surwillo, A.
Wawrzyniak, A.
Powiązania:
https://bibliotekanauki.pl/articles/871890.pdf
Data publikacji:
2013
Wydawca:
Narodowy Instytut Zdrowia Publicznego. Państwowy Zakład Higieny
Tematy:
nutritional assessment
patient
cancer
human nutrition
nutritional status
macroelement
mineral
vitamin
breast cancer
lung cancer
Opis:
Background. It is recognised that both nutritional status and an improper diet have significant effects on weakening the outcomes of treatment in cancer patients. As a result, a lowered response to therapy and an increase in untoward side effects is often observed leading to a deteriorating quality of life. The role of an adequately balanced diet is thus regarded as being vital in supporting recovery. Objective. To assess the dietary consumption of calories, macro-elements and selected vitamins and minerals for subjects diagnosed with cancers of the breast, lungs and bones or soft tissue. Material and Methods. A survey was performed on 100 subjects diagnosed with various tumours between the September and December months of 2011 consisting of 34 with breast cancer, 33 lung cancer and 33 with bone or soft tissue cancer. The questionnaire was devised in-house, which included a three day dietary record. Results. The average daily calorific intake was found to be inadequate at 1608 kcal. In addition, abnormal proportions of energy derived from macro-elements was seen, where the contributions made by fats and proteins were somewhat high at respectively 35.1% and 16.5%, but too low in the case of carbohydrates at 52.1%. Up to 78% subjects had insufficient protein intakes, 88% showed deficiencies in consuming carbohydrates, as were 89% for fibre, 85% vitamin C, 99% calcium, 98% magnesium and 81% for iron. Conclusions. Many dietary shortcomings were observed in the studied subjects. There is therefore a need to educate persons suffering from cancer to adopt an adequate and balanced diet as means of providing vital support for treatment to be more effective.
Wprowadzenie. Nieprawidłowy sposób żywienia oraz stan odżywienia osób z chorobą nowotworową wpływa na słabszą odpowiedź na leczenie przeciwnowotworowe, może nasilać jego objawy uboczne oraz wpływać na jakość życia. Prawidłowo zbilansowana dieta pełni wspomagającą rolę w powrocie do zdrowia. Cel pracy. Celem badań była ocena spożycia energii, makroskładników oraz wybranych witamin i składników mineralnych u osób z diagnozowaną chorobą nowotworową piersi, płuc oraz kości i tkanek miękkich. Materiał i metody. Badanie przeprowadzono w okresie od września do grudnia 2011 roku. Badaną grupę stanowiło 100 osób ze zdiagnozowaną chorobą nowotworową (34 osoby z nowotworem piersi, 33 osoby z nowotworem płuc i 33 osoby z nowotworem kości i tkanek miękkich). Badania przeprowadzono przy użyciu autorskiej ankiety oraz metody 3-dniowego bieżącego notowania. Wyniki. Spożycie energii przez osoby z chorobą nowotworową było niewystarczające i średnio wynosiło 1608 kcal/dzień. Procentowy udział poszczególnych makroskładników w dostarczaniu energii był nieprawidłowy, w przypadku tłuszczu i białka był zbyt wysoki (odpowiednio 35,1% oraz 16,5%), a w przypadku węglowodanów zbyt niski (52,1%). Aż 78% badanych nie realizowało normy na białko, w przypadku węglowodanów wartość ta wynosiła 88%, a dla błonnika 89%. Spożycie witaminy C było zbyt niskie u 85% badanych, wapnia u 99%, magnezu u 89%, a żelaza u 81% badanych. Wnioski. W ocenianych racjach pokarmowych pacjentów obserwowano liczne nieprawidłowości. Istnieje potrzeba edukacji osób z chorobą nowotworową w zakresie zasad prawidłowego żywienia i znaczenia bilansowania diety.
Źródło:
Roczniki Państwowego Zakładu Higieny; 2013, 64, 3
0035-7715
Pojawia się w:
Roczniki Państwowego Zakładu Higieny
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Organizational forms and methods of early diagnosis of hereditary tumors
Autorzy:
Kuzniatsou, A.
Shpakou, A.
Powiązania:
https://bibliotekanauki.pl/articles/2088006.pdf
Data publikacji:
2020
Wydawca:
Uniwersytet Opolski. Instytut Nauk o Zdrowiu
Tematy:
oncology
hereditary cancer
clinical risk
screening
risk
mutation
breast cancer
ovary cancer
colon cancer
Opis:
Background: With the development of genetic research in oncology, it has become possible to track and identify early and preclinical forms of hereditary oncological diseases, which allows timely and effective preventive and therapeutic measures in relation to relatives at risk. Aim of the study: Assessment of genetically determined neoplasms in the region and the development of organizational forms and methods for early diagnosis. Material and methods: 10,727 residents of the Belarus-Poland border region were examined. Clinical and medical history data of 2,054 patients with tumors of the breast (1406), ovaries (239), and colon (409) were analyzed. As a result of the questionnaire, three main observation groups were formed: “high risk of hereditary cancer”, “hereditary cancer suspected”, and “no risk of hereditary cancer”. Results: Register and hospital screenings were the most informative types of screening. Of the 149 HBC patients who underwent molecular genetic testing, BRCA1 gene mutations were found in 5.37%, 5382insC in all cases. Seven mutations were detected in 77 individuals with a diagnosis of HOC and in 6 cases 5382insC and in 2 – 4145delA. Signs of hereditary ovarian cancer and suspicion of it were found in 1.12%, including people who were found to have a high risk of hereditary ovarian cancer. By their effectiveness, register and hospital screenings significantly exceeded the population, p<0.01. 1.67% of women suffering from this disease met the high clinical risk criteria for hereditary ovarian cancer. A high clinical risk of hereditary tumor genesis was established in 0.73% of cases among patients with a diagnosis of colon cancer. Conclusions: The results of assessing the clinical risk of hereditary cancer according to population screening indicates that approximately 1.2% of the population has an increased clinical risk of developing hereditary breast, ovarian, and colon cancer.
Źródło:
Medical Science Pulse; 2020, 14, 1; 15-20
2544-1558
2544-1620
Pojawia się w:
Medical Science Pulse
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Fertility and breast cancer
Autorzy:
Kufel-Grabowska, Joanna
Powiązania:
https://bibliotekanauki.pl/articles/1064776.pdf
Data publikacji:
2016
Wydawca:
Medical Education
Tematy:
breast cancer during pregnancy
breast cancer in young women
fertility
fertility preservation strategies
Opis:
Breast cancer is the most common cancer among females worldwide. The mean age of breast cancer patients is > 60 yrs old, and it is seldom found in women < 40 yrs old (6.5%) and in very young women < 35 yrs old (0.6%). In young females, fertility and all its aspects are an additional therapeutic challenge. Before initiating treatment, the oncologist should offer effective contraception to be applied throughout the therapy, bearing in mind that fertility preservation is of utmost importance. When it comes to breast cancer in pregnancy, the attending physician should use a therapy which is safe for both the mother and the foetus. Chemotherapy, radiotherapy, hormonal therapy and immunotherapy can, to a lesser or greater degree, damage the ovarian function resulting in amenorrhea in women < 50 yrs (33–76%). However, owing to fertility preservation strategies, more and more pregnancies are successful, even in breast cancer survivors.
Źródło:
OncoReview; 2016, 6, 4; A157-161
2450-6125
Pojawia się w:
OncoReview
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Brain metastasis as the first symptom of gastric cancer – case report and literature review
Autorzy:
Murawa, Dawid
Nowaczyk, Piotr
Szymkowiak, Małgorzata
Karaszewska, Bogusława
Powiązania:
https://bibliotekanauki.pl/articles/1396242.pdf
Data publikacji:
2013-07-01
Wydawca:
Index Copernicus International
Tematy:
gastric cancer
gastric cancer symptoms
gastric cancer metastases
brain metastases
Opis:
The study presented a patient with asymptomatic gastric cancer, in whom the first symptom was metastasis to the brain. The patient was initially diagnosed by a neurologist and subject to surgical intervention in the area of residence, where he underwent craniotomy with the excision of the metastatic lesions located in the occipital lobe. The histopathological examination revealed the presence of adenocarcinoma metastases. Following complex diagnostics the patient was diagnosed with cardial carcinoma, being subject to cerebral radiotherapy and chemotherapy. The patient was then referred to surgery at the Wielkopolska Cancer Center in Poznań. After final exclusion of disease dissemination (by means of PET-CT) the patient underwent total gastrectomy with D2 lymphadenectomy, and gastrointestinal tract reconstruction by means of the Roux-en-Y method. The histopathological examination result was as follows: tubular-papillary G2 adenocarcinoma (intestinal type), pT2 pN0 (23 evaluated lymph nodes without cancer metastasis), vascular neoplastic emboli, and positive HER2 protein expression. After surgery the patient was subject to adjuvant chemotherapy. Control brain CT examinations revealed the presence of 4 recurrent metastatic lesions-the patient was disqualified from stereotactic radiation therapy and was subject to palliative chemotherapy. The discussion presented the problem of treating patients with stage IV gastric cancer, including current management guidelines, as well as literature review concerning the treatment of patients with diagnosed gastric cancer and brain metastases.
Źródło:
Polish Journal of Surgery; 2013, 85, 7; 401-406
0032-373X
2299-2847
Pojawia się w:
Polish Journal of Surgery
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Prognostic significance of p53 protein accumulation in cancer cells obtained from selected group of patients with sporadic colorectal cancer
Autorzy:
Paluszkiewicz, P
Karski, J.
Berbec, H.
Pawlowska-Wakowicz, B.
Cybulski, M.
Karski, M.
Paszkowska, A.
Powiązania:
https://bibliotekanauki.pl/articles/2043897.pdf
Data publikacji:
1999
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
patient
cancer cell
monoclonal antibody
p53 protein
cancer prognosis
immunohistochemistry
sporadic colorectal cancer
accumulation
colorectal cancer
Źródło:
Journal of Applied Genetics; 1999, 40, 2; 135-144
1234-1983
Pojawia się w:
Journal of Applied Genetics
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Cancer immunotherapy using cells modified with cytokine genes.
Autorzy:
Kowalczyk, Dariusz
Wysocki, Piotr
Mackiewicz, Andrzej
Powiązania:
https://bibliotekanauki.pl/articles/1043434.pdf
Data publikacji:
2003
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
cancer
cancer vaccines
cytokines
dendritic cells
gene therapy
Opis:
The ability of various cytokines to hamper tumor growth or to induce anti-tumor immune response has resulted in their study as antitumor agents in gene therapy approaches. In this review we will concentrate on the costimulation of antitumor immune responses using modification of various cell types by cytokine genes. Several strategies have emerged such as (i) modification of tumor cells with cytokine genes ex vivo (whole tumor cell vaccines), (ii) ex vivo modification of other cell types for cytokine gene delivery, (iii) delivery of cytokine genes into tumor microenvironment in vivo, (iv) modification of dendritic cells with cytokine genes ex vivo. Originally single cytokine genes were used. Subsequently, multiple cytokine genes were applied simultaneously, or in combination with other factors such as chemokines, membrane bound co-stimulatory molecules, or tumor associated antigens. In this review we discuss these strategies and their use in cancer treatment as well as the promises and limitations of cytokine based cancer gene therapy. Clinical trials, including our own experience, employing the above strategies are discussed.
Źródło:
Acta Biochimica Polonica; 2003, 50, 3; 613-624
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Innovations in lung cancer treatment
Autorzy:
Sieńko, Anna
Rożenek, Karolina
Nalewaj, Piotr
Bożyk, Aleksandra
Krawczyk, Paweł
Powiązania:
https://bibliotekanauki.pl/articles/1178237.pdf
Data publikacji:
2018
Wydawca:
Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
Tematy:
Immunotherapy
Lung cancer
Lung cancer treatment
targeted therapy
Opis:
Lung cancer is associated with one of the highest mortality rates among malignant tumors. It is the main death cause of men and women in Poland where over 15 000 men and 7 000 women die with this diagnosis annually. 1.7 million people die every year due to lung cancer in the world. Two main types of lung cancer are small cell lung cancer (SCLC) and non-small cell lung cancer (NSCLC). The history of lung cancer treatment begins with surgical approach followed by addition of chemotherapy and radiotherapy, which were used either separately or in combination depending on the stage of the lung cancer. Many somatic mutations were identified and molecularly targeted therapies could have been established. One of the oldest and the best known group of molecularly targeted drugs used in lung cancer treatment are tyrosine kinase inhibitors (TKIs) of epidermal growth factor receptor (EGFR). First EGFR-TKI was gefitinib, which has been examined in clinical trials before erlotinib, afatinib, dacomitinib and osimertinib. EGFR-TKIs increased overall survival (OS) with significantly less side effects when compared to standard chemotherapy. Another group of molecularly targeted drugs are anaplastic lymphoma (ALK) kinase inhibitors such as crizotinib, alectinib and ceritinib. Another innovation which was introduced in NSCLC treatment was immunotherapy. Its effect is based on modification of immune system leading to activation of cytotoxic T lymphocytes (CTL). Currently nivolumab and pembrolizumab (anti-PD1 antibodies) as well as atezoliumab (anti-PD-L1 antibody) are being used in NSCLC patients. The discovery of innovative therapies for NSCLC patients resulted in significant extension of patients' life expectancy while minimizing the side effects of such therapy. Moreover, the quality of patients’ life was significantly improved. However, important problems still remain to be solved: overcoming the resistance in the course of molecularly targeted therapies and the lack of predictive factors that determine the effectiveness of immunotherapy.
Źródło:
World Scientific News; 2018, 93; 115-124
2392-2192
Pojawia się w:
World Scientific News
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Mental adaptation to cancer in women with gynaecological cancer
Autorzy:
Kupcewicz, Ewa
Olewińska, Joanna
Pikus, Hanna
Jóźwik, Marcin
Powiązania:
https://bibliotekanauki.pl/articles/972487.pdf
Data publikacji:
2017
Wydawca:
Instytut Medycyny Wsi
Tematy:
mental adaptation
stress
coping strategies
cancer
Opis:
Introduction and objective. Adapting to gynaecological cancer is the problem of accepting and coping with the disease and its consequences. The aim of this study is to analyze the relationship between stress intensity and strategies for coping with stress and psychological adaptation to disease in women diagnosed with gynaecological cancer. Materials and method. The study was performed on a group of 102 women diagnosed with gynaecologic malignancy. The mean age of patients was 56.1 (SD ±10.75) years. Three self- designed questionnaires were used to carry out the study: Scale of Perceived Stress (PSS-10), Multidimensional Inventory for Measuring Coping with Stress (Mini-COPE) and the Scale of Mental Adaptation to Cancer (Mini-MAC). Statistical significance was set at p <0.05. Results. In more than half of the women surveyed, the severity of stress experienced during the last month was high. Women with a malignant illness significantly differed (p<0.001) in the styles of coping with the disease, preferring a constructive style (M=43.5; SD±5.76) rather than a destructive style (M=21.7; SD±5.28). The highest median values were obtained by positive revalidation (M=21.9; SD±3.01) and fighting spirit (M=21.6; SD±3.47) strategies. The most prominent indicator of predicting a constructive style of coping with cancer was the coping strategy described as Positive Revalidation (ßeta=0.38; R²=0.41); whereas an Acceptance strategy was a predictor of a destructive style (ßeta=-0.30; R²=0.31). Conclusions. Most women facing gynaecological cancer experience a high level of stress, and try to use active strategies to deal with the disease. The results indicate that there is a need to offer special psychological care to oncologically diagnosed women.
Źródło:
Journal of Pre-Clinical and Clinical Research; 2017, 11, 2; 120-126
1898-2395
Pojawia się w:
Journal of Pre-Clinical and Clinical Research
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Modern diagnostics of early glottic cancer
Autorzy:
Rzepakowska, Anna
Powiązania:
https://bibliotekanauki.pl/articles/1399297.pdf
Data publikacji:
2020
Wydawca:
Index Copernicus International
Tematy:
diagnosis
dysplasia
endoscopy
glottic cancer
Opis:
This article is a review of literature and a summary of the current guidelines in the diagnosis of hypertrophic vocal folds lesions suspected of malignancy. It gives a detailed overview both of initial diagnosis, as well as the methods of in-depth intraoperative diagnostics and proposals for careful evaluation during post-treatment follow-up examinations.
Źródło:
Polski Przegląd Otorynolaryngologiczny; 2020, 9, 4; 45-50
2084-5308
2300-7338
Pojawia się w:
Polski Przegląd Otorynolaryngologiczny
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Serum and saliva levels of matrix metalloproteinase 3 and 9 in pharynx and larynx cancer
Autorzy:
Polz-Dacewicz, Małgorzata
Maciąg, Paweł
Kliszczewska, Ewa
Rolniak, Łukasz
Powiązania:
https://bibliotekanauki.pl/articles/972529.pdf
Data publikacji:
2017
Wydawca:
Instytut Medycyny Wsi
Tematy:
matrix metalloproteinases
larynx cancer
throat cancer
head and neck cancer
Opis:
Introduction and objective. Matrix metalloproteinases (MMPs) are proteolytic enzymes responsible for the decomposition of extracellular matrix elements. They play an important role during embryogenesis, wound healing, endometrial epithelial exfoliation, the formation of new blood vessels, and also during cancer development. Throat and larynx tumours are included in a large group of head and neck cancers. These tumours are characterized by a poor prognosis. Despite advances in medical science, cancer treatment is difficult and often ineffective. The aim of the study was to evaluate the level of MMP-3 and MMP-9 in the serum and saliva of patients with pharynx and larynx tumours. Materials and method. Samples of saliva and serum were collected from 60 patients with larynx or throat cancer. Twenty patients without cancer comprised the control group. MMPs in saliva and serum were determined by the ELISA method. Results. In the study group, concentrations of MMP-3 in saliva were from 0.2 – 77.6 ng/ml. Patients with malignant tumours had higher saliva MMP-3 levels than healthy subjects. The concentration of MMP-3 in the serum of the study group ranged from 10.9 – 200.00 ng/ml, which was also higher than in the control group. There were no statistically significant difference in the MMP-9 level between the study and control groups (both in serum and saliva). Conclusions. This study is another element that shows the phenomena taking place at the cellular level during oncological disease. In serum and saliva samples, higher values of MMP3 were found in patients with cancer. The increase in the concentration of this enzyme in the risk group may be used for early detection of tumour transformation and evaluation of treatment.
Źródło:
Journal of Pre-Clinical and Clinical Research; 2017, 11, 2; 106-110
1898-2395
Pojawia się w:
Journal of Pre-Clinical and Clinical Research
Dostawca treści:
Biblioteka Nauki
Artykuł
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