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Tytuł:
Recovery of Proteins from Sweet Potato Cell Liquid by Acidification via Inoculation-Enhanced Fermentation and Determination of Functional Properties of Protein Products
Autorzy:
Li, Qingshuai
Liu, Liping
Han, Yanlei
Zhao, Xiangying
Yao, Mingjing
Ma, Jing
Han, Mo
Zhang, Jiaxiang
Powiązania:
https://bibliotekanauki.pl/articles/28408449.pdf
Data publikacji:
2024-02-09
Wydawca:
Instytut Rozrodu Zwierząt i Badań Żywności Polskiej Akademii Nauk w Olsztynie
Tematy:
sweet potato proteins
Leuconostoc citreum
protein precipitation
digestibility
emulsification
foaming
Opis:
Starch production from fresh sweet potatoes generates process wastewater called sweet potato cell liquid (SPCL), which is rich in sweet potato protein (SPP). Currently, the commonly used protein recovery methods, such as isoelectric point precipitation and ultrafiltration, were not suitable for SPP recovery due to the low protein content of SPCL and the high cost of recovery. The feasibility of recovering SPP by SPCL acidification via inoculation-assisted fermentation was investigated in this study. The results indicated that the pH of SPCL could be reduced to approximately 4.0 within 6 h of fermentation with inoculation, resulting in an SPP extraction yield of 55.45% and purity of 66.23 g protein/100 g. With the addition of heating treatment, the extraction yield of SPP increased to 76.97–95.34%, while it maintained the purity of 66.36–70.12 g protein/100 g. The composition analysis revealed that SPP products contained sugars (below 11.5 g/100 g) in addition to protein and trace amounts of lignin and phenolics. Functional properties analysis showed that the SPP recovered by inoculation-enhanced fermentation exhibited better emulsifying and foaming properties, and higher digestibility compared to the SPP precipitated using hydrochloric acid. The method of extracting SPP from SPCL by inoculation-enhanced fermentation, as developed in this study, was a straightforward and cost-effective process that fosters significant potential for industrial applications.
Źródło:
Polish Journal of Food and Nutrition Sciences; 2024, 74, 1; 49-58
1230-0322
2083-6007
Pojawia się w:
Polish Journal of Food and Nutrition Sciences
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
A genetic algorithm-based approach for flexible job shop rescheduling problem with machine failure interference
Autorzy:
Liang, Zhongyuan
Zhong, Peisi
Zhang, Chao
Yang, Wenlei
Xiong, Wei
Yang, Shihao
Meng, Jing
Powiązania:
https://bibliotekanauki.pl/articles/27320976.pdf
Data publikacji:
2023
Wydawca:
Polska Akademia Nauk. Polskie Naukowo-Techniczne Towarzystwo Eksploatacyjne PAN
Tematy:
genetic algorithm
rescheduling
machine failure
flexible job shop scheduling
Opis:
Rescheduling is the guarantee to maintain the reliable operation of production system process. In production system, the original scheduling scheme cannot be carried out when machine breaks down. It is necessary to transfer the production tasks in the failure cycle and replan the production path to ensure that the production tasks are completed on time and maintain the stability of production system. To address this issue, in this paper, we studied the event-driven rescheduling policy in dynamic environment, and established the usage rules of right-shift rescheduling and complete rescheduling based on the type of interference events. And then, we proposed the rescheduling decision method based on genetic algorithm for solving flexible job shop scheduling problem with machine fault interference. In addition, we extended the "mk" series of instances by introducing the machine fault interference information. The solution data show that the complete rescheduling method can respond effectively to the rescheduling of flexible job shop scheduling problem with machine failure interference.
Źródło:
Eksploatacja i Niezawodność; 2023, 25, 4; art. no. 171784
1507-2711
Pojawia się w:
Eksploatacja i Niezawodność
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Event-triggered cooperative control for high-order nonlinear multi-agent systems with finite-time consensus
Autorzy:
Gong, Shiyin
Zheng, Meirong
Hu, Jing
Zhang, Anguo
Powiązania:
https://bibliotekanauki.pl/articles/24200691.pdf
Data publikacji:
2023
Wydawca:
Uniwersytet Zielonogórski. Oficyna Wydawnicza
Tematy:
multiagent system
cooperative control
event triggered control
neuroadaptive control
prescribed performance
system wieloagentowy
sterowanie wyzwalane zdarzeniami
sterowanie neuroadaptacyjne
Opis:
An event-triggered adaptive control algorithm is proposed for cooperative tracking control of high-order nonlinear multiagent systems (MASs) with prescribed performance and full-state constraints. The algorithm combines dynamic surface technology and the backstepping recursive design method, with radial basis function neural networks (RBFNNs) used to approximate the unknown nonlinearity. The barrier Lyapunov function and finite-time stability theory are employed to prove that all agent states are semi-globally uniform and ultimately bounded, with the tracking error converging to a bounded neighborhood of zero in a finite time. Numerical simulations are provided to demonstrate the effectiveness of the proposed control scheme.
Źródło:
International Journal of Applied Mathematics and Computer Science; 2023, 33, 3; 439--448
1641-876X
2083-8492
Pojawia się w:
International Journal of Applied Mathematics and Computer Science
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Research on communication emitter identification based on semi-supervised dimensionality reduction in complex electromagnetic environment
Autorzy:
Ge, Wei
Qi, Lin
Tong, Lin
Zhu, Jun
Zhang, Jing
Zhao, Dongyang
Li, Ke
Powiązania:
https://bibliotekanauki.pl/articles/27311449.pdf
Data publikacji:
2023
Wydawca:
Polska Akademia Nauk. Czasopisma i Monografie PAN
Tematy:
communication emitter identification
feature extraction
dimensionality reduction
VMD
ESDA
variational mode decomposition
exponential semi-supervised discriminant analysis
identyfikacja emitera komunikacyjnego
ekstrakcja cech
redukcja wymiarowości
rozkład w trybie wariacyjnym
analiza dyskryminacyjna wykładnicza półnadzorowana
Opis:
The individual identification of communication emitters is a process of identifying different emitters based on the radio frequency fingerprint features extracted from the received signals. Due to the inherent non-linearity of the emitter power amplifier, the fingerprints provide distinguishing features for emitter identification. In this study, approximate entropy is introduced into variational mode decomposition, whose features performed in each mode which is decomposed from the reconstructed signal are extracted while the local minimum removal method is used to filter out the noise mode to improve SNR. We proposed a semi-supervised dimensionality reduction method named exponential semi-supervised discriminant analysis in order to reduce the high-dimensional feature vectors of the signals, and LightGBM is applied to build a classifier for communication emitter identification. The experimental results show that the method performs better than the state-of-the-art individual communication emitter identification technology for the steady signal data set of radio stations with the same plant, batch and model.
Źródło:
Bulletin of the Polish Academy of Sciences. Technical Sciences; 2023, 71, 4; art. no. e145766
0239-7528
Pojawia się w:
Bulletin of the Polish Academy of Sciences. Technical Sciences
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Simulation of the peak flow reduction of small reservoirs. A case study of the Brown Bridge Pond, Michigan, USA
Autorzy:
Zhang, Jing
Guo, Chen-lin
Xie, Guang-Ming
Xing, Bing
Powiązania:
https://bibliotekanauki.pl/articles/27323980.pdf
Data publikacji:
2023
Wydawca:
Politechnika Wrocławska. Oficyna Wydawnicza Politechniki Wrocławskiej
Opis:
Due to the high frequency and great damage of flood disasters, it is important to reduce the flood peak when it goes through the reservoir. A hydraulic model which integrates the implicit equation of water balance, water head-discharge carves, and water head-storage carves together, is proposed to simulate the flood peak reduction of a small reservoir. The proposed method was employed to simulate the flood peak reduction in the Brown Bridge Reservoir, Michigan, US. The results show that the proposed method can simulate the flood peak reduction in a small reservoir, and the Brown Bridge Dam can reduce the flood peak when hundred-year floods go through. When all gates or spillways are fully opened, the initial water head of the reservoir significantly influences the capacity of flood peak reduction. When the initial water head of the Brown Bridge Reservoir is 240.18 and 241.40 m, the hundred-year flood peak would be reduced to 23.11 m3/s and 25.85 m3/s, respectively. By optimizing the gates or spillways, the hundred-year flood peak could be reduced. When the initial water head of the reservoir is 241.40 and 240.18 m, the hundred-year flood peak would be reduced to 17.98 and 16.54 m3/s, respectively
Źródło:
Environment Protection Engineering; 2023, 49, 3; 83--94
0324-8828
Pojawia się w:
Environment Protection Engineering
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Analiza motywacji, problemów i potrzeb chińskich młodszych nauczycieli języka polskiego jako obcego
Analysis of motivation, problems, and needs of Chinese junior teachers of Polish as a foreign language
Autorzy:
Wang, Jing
Zhang, Huiling
Cao, Yang
Powiązania:
https://bibliotekanauki.pl/articles/31339962.pdf
Data publikacji:
2022
Wydawca:
Uniwersytet Gdański. Wydawnictwo Uniwersytetu Gdańskiego
Opis:
With the dynamic development of Chinese Polish Studies since 2018, there has been a growing demand for teachers of Polish as a foreign language who are native Chinese speakers in the labour market of the People’s Republic of China. Nowadays, almost every Polish language centre at a university has its own teaching staff. Many of them are not only quite modest in terms of staff numbers, but also very young in terms of the age and experience of the teachers. Today, both Polish and Chinese language literature still lacks in-depth research on this specific group of glottodidactics. Therefore, the present study aims at getting to know Chinese junior teachers of Polish as a foreign language working at universities, and to gain knowledge about their motivation for their profession, problems and needs at work. From the questionnaire survey of 23 purposively selected respondents, it can be concluded that the greatest motivation of the respondents was related to students and interests in research and/or teaching. The problems they encountered at work were related to insufficient skills, lack of materials and those caused by the work environment. They are most in need of improved teaching methods and techniques, more and better teaching materials and help from masters in this field.
Źródło:
Gdańskie Studia Azji Wschodniej; 2022, 21; 129-145
2353-8724
Pojawia się w:
Gdańskie Studia Azji Wschodniej
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Polarization dependent high refractive index metamaterial with metallic dielectric grating structure in infrared band
Autorzy:
Li, Jianmin
Chen, Peng
Fang, Bo
Cai, Jinhui
Zhang, Le
Wu, Yinglai
Jing, Xufeng
Powiązania:
https://bibliotekanauki.pl/articles/2172825.pdf
Data publikacji:
2022
Wydawca:
Politechnika Wrocławska. Oficyna Wydawnicza Politechniki Wrocławskiej
Tematy:
metamaterial
high refractive index
infrared band
Opis:
According to the theory of high refractive index of metamaterials, a composite structure of metal dielectric grating was designed to achieve high refractive index in infrared band. Based on the S-parameter inversion algorithm, we extracted the effective permittivity, the effective permeability, and the effective refractive index of the designed metamaterial. By changing the geometric parameters of the composite grating metamaterial structure, the effective refractive index of the designed metamaterial reaches more than 8.0 at the infrared resonance frequency. This is a high refractive index that many natural materials cannot achieve. It is noteworthy that the metamaterial structure has obvious polarization sensitivity. The metamaterial structure has both high refractive index and wideband zero refractive index properties when different polarized light is incident. At the same time, we further investigate the influence of metamaterial geometric parameters on the effective refractive index of metamaterials. Also, we propose a double grating metamaterial structure to obtain more degrees of freedom of metamaterial on the effective refractive index.
Źródło:
Optica Applicata; 2022, 52, 3; 441--460
0078-5466
1899-7015
Pojawia się w:
Optica Applicata
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Simulation of Dendrite Morphology and Micro-Segregation in U-Nb Alloy During Solidification
Autorzy:
Su, Bin
Liu, Jing-Yuan
Zhang, Xiao-Peng
Yan, Xue-Wei
Powiązania:
https://bibliotekanauki.pl/articles/2174585.pdf
Data publikacji:
2022
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
U-Nb alloys
solidification process
dendrite growth
cellular automaton
numerical simulation
Opis:
Due to the importance of uranium and uranium alloys to national defence and nuclear industrial applications, it is necessary to understand dendrite formation in their solidification structures and to control their microstructures. In this study, a modified cellular automaton model was developed to predict 2-D and 3-D equiaxed dendrite growth in U-Nb alloys. The model takes into account solute diffusion, preferential growth orientation, interface curvature, etc., and the solid fraction increment is calculated using the local level rule method. Using this model, 2-D large-scale and 3-D equiaxed dendrite growth with various crystallographic orientations in the U-5.5Nb alloy were simulated, and the Nb micro-segregation behaviour during solidification was analysed. The simulated results showed reasonable agreement with the as-cast microstructure observed experimentally.
Źródło:
Archives of Metallurgy and Materials; 2022, 67, 4; 1333--1339
1733-3490
Pojawia się w:
Archives of Metallurgy and Materials
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Simulation of the migration path of the maximum pollutants’ concentration. Case study of the tailing pond, southwest China
Autorzy:
Zhang, Jing
Ma, Yong
Xing, Bing
Zhang, Jian-Min
Ren, Yu-Feng
Liang, Yue
Powiązania:
https://bibliotekanauki.pl/articles/2086910.pdf
Data publikacji:
2022
Wydawca:
Politechnika Wrocławska. Oficyna Wydawnicza Politechniki Wrocławskiej
Tematy:
groundwaters
tailing pond
zinc mine
lead mine
ground contaminants
wody gruntowe
staw osadowy
kopalnia cynku
kopalnia ołowiu
zanieczyszczenie gruntu
Opis:
Following China's economic development, lots of tailing deposits have become potential pollution sources, and their leaching would release the trace elements into the natural environment. The leakage rate model and the solute transport models of groundwater are coupled to investigate the effects of the tailing ponds on groundwater. It indicates that the anti-seepage layer is a necessary and important component of the tailing ponds, which could protect the soil or groundwater to be polluted by wastewater. Under three scenarios (scenario A - ideal conditions, scenario B - the worst conditions, and scenario C), the proportions of maximum concentration to source concentration are 1.2, 94.6, and 19.1%, respectively. Under the worst states of anti-seepage layers, the pollution areas after 730, 1800, 3807 and 7300 days were 130 500, 313 200, 523 800, and 729 000 m2, respectively. Compared with Scenario B, the pollution areas of Scenario C after 1800, 3807, and 7300 days were cut by 52.97, 74.55, and 81.73, respectively. Given important anti-seepage layers, the tracking monitor system is necessary and important to discover whether the groundwater was contaminated in time.
Źródło:
Environment Protection Engineering; 2022, 48, 2; 59--72
0324-8828
Pojawia się w:
Environment Protection Engineering
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Study on fluoride fixation effect of Bayan Obo rare earth iron ore and three sodium agents under microwave irradiation
Autorzy:
Guo, Jing
Wen, Ming
Li, Jie
Hong, Xunhai
Zhang, Wenhao
Wang, Yonglun
Powiązania:
https://bibliotekanauki.pl/articles/2146846.pdf
Data publikacji:
2022
Wydawca:
Politechnika Wrocławska. Oficyna Wydawnicza Politechniki Wrocławskiej
Tematy:
Bayan Obo rare earth iron ore
microwave roasting
sodium agent fluoride fixation
Opis:
To investigate the fluorine fixation of Bayan Obo rare-earth iron ores in beneficiation and metallurgy processes, the effect of three sodium agents, namely, sodium hydroxide, sodium carbonate, and sodium bicarbonate, on fluorine fixation under the action of microwaves was investigated using Xray diffraction, chemical detection, and orthogonal experiments. The effects of different types of sodium, roasting temperatures, sodium ratios, and roasting times on the fluorine fixation rate were evaluated. Results show that compared with conventional roasting, the fluorine fixation efficiency of Bayan Obo rare-earth iron ore under the action of microwave is superior after the formulation of the sodium agent, which is crucial for the study. Among the three sodium agents, the fluorine fixation effect of NaHCO3 can be used as the preferred sodium agent. Orthogonal experiments showed that the factors influencing the magnitude of the fluorine fixation rate are the roasting temperature, sodium agent ratio, and roasting constant temperature time in the order of priority. The optimal conditions for the fluorine fixation process are the microwave roasting temperature of 973.15 K, sodium bicarbonate ratio of 40%, and roasting time of 60 min. The highest fluorine fixation rate of 86.72% can be obtained. The findings of this study can provide a reference for the development of green and economic recovery processes for Bayan Obo rare-earth iron ores.
Źródło:
Physicochemical Problems of Mineral Processing; 2022, 58, 1; 63--76
1643-1049
2084-4735
Pojawia się w:
Physicochemical Problems of Mineral Processing
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
The influences of source intensity and meteorological factors on sulfur dioxide and nitrogen oxides based on the path analysis mode
Autorzy:
Guo, Chen-Lin
Zhang, Jing
Zhou, Qian Shuang
Ma, Yong
Powiązania:
https://bibliotekanauki.pl/articles/2171846.pdf
Data publikacji:
2022
Wydawca:
Politechnika Wrocławska. Oficyna Wydawnicza Politechniki Wrocławskiej
Tematy:
meteorological factor
analysis model
sulfur dioxide
nitrogen dioxide
czynnik meteorologiczny
model analityczny
dwutlenek siarki
tlenek azotu
Opis:
With rapid economic development and industrialization, air pollution is becoming a critical global issue affecting health. Sulfur dioxide and nitrogen oxides are the major contributors to acid rain and the key indicators for evaluating atmospheric pollution. And source intensity and meteorological factors are the main ways to influence the concentrations of sulfur dioxide and nitrogen oxides. Thus, to investigate the specific effects of source intensity, temperature, humidity, wind speed and atmospheric pressure on SO2 and NOx, the path analysis method was used for the model. The results showed that Source intensity significantly affects the concentrations of SO2and NO2. For both NO2 and SO2, the source intensity accounted for around 40%. Meteorological factors have very limited effects on the concentrations of SO2and NO2. The effects of the meteorological factors on air pollutants are specific as differences in material properties. Humidity significantly affects the concentration of SO2while temperature, humidity and wind speed have significantly affected the concentration of NO2.
Źródło:
Environment Protection Engineering; 2022, 48, 4; 51--65
0324-8828
Pojawia się w:
Environment Protection Engineering
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
A novel combinational evaluation method of voltage and reactive power in regional power grid containing renewable energy
Autorzy:
Ji, Yuqi
Chen, Xuehan
Xiao, Han
Shi, Shaoyu
Kang, Jing
Wang, Jialin
Zhang, Shaofeng
Powiązania:
https://bibliotekanauki.pl/articles/1955201.pdf
Data publikacji:
2021
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
adaptive weighting coefficient
combinational evaluation
renewable energy
typical scenarios
adaptacyjny współczynnik wagowy
ocena kombinacyjna
energia odnawialna
typowy scenariusz
Opis:
The output of renewable energy is strongly uncertain and random, and the distribution of voltage and reactive power in regional power grids is changed with the access to large-scale renewable energy. In order to quantitatively evaluate the influence of renewable energy access on voltage and reactive power operation, a novel combinational evaluation method of voltage and reactive power in regional power grids containing renewable energy is proposed. Firstly, the actual operation data of renewable energy and load demand are clustered based on the K-means algorithm, and several typical scenarios are divided. Then, the entropy weight method (EWM) and the analytic hierarchy process (AHP) are combined to evaluate the voltage qualified rate, voltage fluctuation, power factor qualified rate and reactive power reserve in typical scenarios. Besides, the evaluation results are used as the training samples for back-propagation (BP) neural networks. The proposed combinational evaluation method can calculate the weight coefficient of the indexes adaptively with the change of samples, which simplifies the calculation process of the indexes’ weight. At last, the case simulation of an actual regional power grid is provided, and the historical data of one year is taken as the sample for training, evaluating and analyzing. And finally, the effectiveness of the proposed method is verified based on the comparison with the existing method. The evaluated results could provide reference and guidance to the operation analysis and planning of renewable energy.
Źródło:
Archives of Electrical Engineering; 2021, 70, 4; 925-942
1427-4221
2300-2506
Pojawia się w:
Archives of Electrical Engineering
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Color image encryption scheme based on quaternion discrete multi-fractional random transform and compressive sensing
Autorzy:
Ye, Huo-Sheng
Dai, Jing-Yi
Wen, Shun-Xi
Gong, Li-Hua
Zhang, Wen-Quan
Powiązania:
https://bibliotekanauki.pl/articles/2033985.pdf
Data publikacji:
2021
Wydawca:
Politechnika Wrocławska. Oficyna Wydawnicza Politechniki Wrocławskiej
Tematy:
color image encryption
quaternion discrete multi-fractional random transform
compressive sensing
confusion-diffusion strategy
Opis:
A color image compression-encryption algorithm by combining quaternion discrete multi-fractional random transform with compressive sensing is investigated, in which the chaos-based fractional orders greatly improve key sensitivity. The original color image is compressed and encrypted with the assistance of compressive sensing, in which the partial Hadamard matrix adopted as a measurement matrix is constructed by iterating Chebyshev map instead of utilizing the entire Guassian matrix as a key. The sparse images are divided into 12 sub-images and then represented as three quaternion signals, which are modulated by the quaternion discrete multi-fractional random transform. The image blocking and the quaternion representation make the proposed cryptosystem avoid additional data extension existing in many transform-based methods. To further improve the level of security, the plaintext-related key streams generated by the 2D logistic-sine-coupling map are adopted to diffuse and confuse the intermediate results simultaneously. Consequently, the final ciphertext image is attained. Simulation results reveal that the proposed cryptosystem is feasible with high security and has strong robustness against various attacks.
Źródło:
Optica Applicata; 2021, 51, 3; 349-364
0078-5466
1899-7015
Pojawia się w:
Optica Applicata
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Digital watermarking algorithm based on 4-level discrete wavelet transform and discrete fractional angular transform
Autorzy:
Li, Jing-You
Zhao, Chun-Hui
Zhang, Guang-Da
Powiązania:
https://bibliotekanauki.pl/articles/2033921.pdf
Data publikacji:
2021
Wydawca:
Politechnika Wrocławska. Oficyna Wydawnicza Politechniki Wrocławskiej
Tematy:
digital watermarking algorithm
mix optical bistability
Harris feature point detection
discrete wavelet transform
discrete fractional angular transform
singular value decomposition
Opis:
Nowadays, there are many watermarking algorithms based on wavelet transform. The simple one is to insert directly the watermark into the wavelet transform coefficients. However, most of the existing watermarking schemes can only resist traditional signal processing attacks, such as image compression, noise and filtering. When the watermarked image is subject to geometric transformations, especially rotation attack, it is hard to detect the watermark successfully. In this paper, a digital watermarking algorithm is proposed based on 4-level discrete wavelet transform and discrete fractional angular transform. To enhance the security of the algorithm, the watermark is scrambled with the simplicity of Arnold transform and chaos-based mix optical bistability model, since the chaos is pseudorandom and sensitive to the initial values. And the watermark is embedded into the medium frequency sub-band of the 1-level wavelet decomposition according to the Harris feature point detection. Simulation results show that the proposed digital watermarking algorithm by combining 4-level discrete wavelet transform with discrete fractional angular transform could resist rotation attack and other common attacks.
Źródło:
Optica Applicata; 2021, 51, 4; 605-619
0078-5466
1899-7015
Pojawia się w:
Optica Applicata
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Evaluation of differential serum expression of three factors and pulmonary function in patients with silicosis
Autorzy:
Zhu, Ying
Duan, Xia Yu
Cheng, Yun Qi
Yao, Xin Jing
Xu, Hong
Zhang, Kui Sheng
Li, Feng Shi
Yang, Fang
Liu, Liang He
Yuan, Xiang Ju
Powiązania:
https://bibliotekanauki.pl/articles/2086531.pdf
Data publikacji:
2021-08-05
Wydawca:
Instytut Medycyny Pracy im. prof. dra Jerzego Nofera w Łodzi
Tematy:
silicosis
pulmonary function
early diagnosis
ROC
PTPN2
factor B
Opis:
ObjectivesSilicosis is a chronic occupational lung disease. As was previously found by the authors, some proteins increased in the lung tissue of activated rats, and protein tyrosine phosphatase non-receptor type 2 (PTPN2), factor B, and vaccinia-related kinase 1 (VRK1) showed highly differential expressions.Material and MethodsIn this study, serum and bronchoalveolar lavage fluid samples were collected from patients with silicosis and healthy people to verify the expression of PTPN2, factor B, and VRK1. The diagnostic value of differentially expressed proteins for silicosis was judged.ResultsThe expression levels of serum PTPN2, VRK1, and factor B in patients with silicosis were significantly higher than those in the control group (p < 0.01). Higher serum PTPN2 and factor B concentrations significantly and negatively correlated with the ratio of forced expiratory volume in 1 s to forced vital capacity (FEV1/FVC), maximum vital capacity (VCmax), FEV1, and FVC, suggesting that the high expression of PTPN2 and factor B is associated with decreased pulmonary ventilation function and restrictive ventilatory impairment in patients with silicosis. All area under curve (AUC) measurements generated from single detection events were >0.744, with PTPN2 reaching the highest value (0.858). The AUC, sensitivity, and specificity for the combined diagnosis using factor B and PTPN2 were 0.907, 86.91% and 85.07%, respectively, for factor B and PTPN2. The 3 differentially expressed proteins are potential classes of predictive biomarkers for silicosis.ConclusionsRegarding the economy and test practicality, the best diagnostic combination is factor B and PTPN2 for the analysis of AUC, sensitivity and specificity.
Źródło:
International Journal of Occupational Medicine and Environmental Health; 2021, 34, 4; 527-540
1232-1087
1896-494X
Pojawia się w:
International Journal of Occupational Medicine and Environmental Health
Dostawca treści:
Biblioteka Nauki
Artykuł
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