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Tytuł:
Order unicyclic graphs according to spectral radius of unoriented laplacian matrix
Autorzy:
Fan, Yi-Zheng
Wu, Song
Powiązania:
https://bibliotekanauki.pl/articles/743077.pdf
Data publikacji:
2008
Wydawca:
Uniwersytet Zielonogórski. Wydział Matematyki, Informatyki i Ekonometrii
Tematy:
unicyclic graph
Laplacian matrix
spectral radius
Opis:
The spectral radius of a graph is defined by that of its unoriented Laplacian matrix. In this paper, we determine the unicyclic graphs respectively with the third and the fourth largest spectral radius among all unicyclic graphs of given order.
Źródło:
Discussiones Mathematicae Graph Theory; 2008, 28, 3; 487-499
2083-5892
Pojawia się w:
Discussiones Mathematicae Graph Theory
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
CAMPTOTHECIN INHIBITS MIGRATION, INVASION AND CLONOGENIC PROPERTY OF LIVER CANCER CELLS BY MODULATING MICRORNA EXPRESSION
Autorzy:
Liu, Zhenzhong
Wu, Song
Li, Xiaoqian
Powiązania:
https://bibliotekanauki.pl/articles/895460.pdf
Data publikacji:
2020-04-29
Wydawca:
Polskie Towarzystwo Farmaceutyczne
Tematy:
Hepatocellular Carcinoma
cell proliferation
cell cycle
Camptothecin
miRNA
Opis:
Camptothecin (CPT), an alkaloid natural product, extracted from Camptotheca acuminata bark, has been reported to have potential antitumor activity in diverse cancers. MicroRNAs (MiRNAs) are a class of short, non-coding RNAs that plays a crucial role in the normal physiology by attenuating translation. Here, we showed that the CPT modulates the expression of miRNAs in hepatocellular carcinoma cells (HCC). Microarray analysis reveals that CPT modulates the expression of as many as 39 miRNAs in HCC cells (Huh7), 27 miRNAs were downregulated whereas 12 miRNAs were upregulated. miR-16 is the key miRNA upregulated by CPT and targets key prosurvival proteins (MMP-2, MMP-9 and cyclin D1). Our results demonstrate that CPT is inhibiting cell viability of HCC cells significantly when compared with the untreated cells. Wound healing and colony formation assay confirm inhibition of cell migration and clonogenic property of Huh7 cells respectively, upon the dose-dependent treatment of CPT. Furthermore, the Boyden chamber assay analysis revealed a significant inhibition of number of invasive cells in CPT treated cells with comparison to untreated Huh7 cells. Mechanistically, CPT upregulates miR-16 expression which targets MMP-2, MMP-9, cyclin D1 downregulation and subsequently upregulates the expression of E-cadherin, TIMP1, p21, and p27, thereby inhibits cell migration, invasion and clonogenic property of HCC cells. In summary, CPT treatment in Huh7 cells decreases cell viability and upregulates miR-16 expression, which results in inhibition of cell migration, invasion and clonogenic property of cells, by decreasing MMP-2, MMP-9, cyclin D1 and increasing the expression of cell cycle-regulated proteins p21 and p27.
Źródło:
Acta Poloniae Pharmaceutica - Drug Research; 2020, 77, 2; 295-304
0001-6837
2353-5288
Pojawia się w:
Acta Poloniae Pharmaceutica - Drug Research
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
A counterexample in comonotone approximation in $L^p$ space
Autorzy:
Wu, Xiang
Zhou, Song
Powiązania:
https://bibliotekanauki.pl/articles/1396162.pdf
Data publikacji:
1993
Wydawca:
Polska Akademia Nauk. Instytut Matematyczny PAN
Opis:
Refining the idea used in [24] and employing very careful computation, the present paper shows that for 0 < p ≤ ∞ and k ≥ 1, there exists a function $f ∈ C_{[-1,1]}^k$, with $f^{(k)}(x)≥ 0$ for x ∈ [0,1] and $f^{(k)}(x) ≤ 0$ for x ∈ [-1,0], such that lim sup_{n→∞} (e_n^{(k)}(f)_p) / (ω_{k+2+[1/p]}(f,n^{-1})_{p}) = + ∞ where $e_n^{(k)}(f)_p$ is the best approximation of degree n to f in $L^p$ by polynomials which are comonotone with f, that is, polynomials P so that $P^{(k)}(x)f^{(k)}(x) ≥ 0$ for all x ∈ [-1,1]. This theorem, which is a particular case of a more general one, gives a complete solution to the converse result in comonotone approximation in $L^p$ space for 1 < p ≤ ∞.
Źródło:
Colloquium Mathematicum; 1993, 64, 2; 265-274
0010-1354
Pojawia się w:
Colloquium Mathematicum
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Temporal and spatial heterogeneity of the Ailaoshan–Song Ma–Song Chay ophiolitic mélange, and its significance on the evolution of Paleo-Tethys
Autorzy:
Lin, Wei
Liu, Fei
Wang, Ying
Meng, Lingtong
Faure, Michel
Chu, Yang
Nguyen, Vuong Van
Wu, Qinying
We, Wei
Thu, Hoai Luong Thi
Vu, Tich Van
Powiązania:
https://bibliotekanauki.pl/articles/24202127.pdf
Data publikacji:
2023
Wydawca:
Akademia Górniczo-Hutnicza im. Stanisława Staszica w Krakowie. Wydawnictwo AGH
Tematy:
Tethys
heterogeneity
Vietnam
Opis:
The ophiolite is the direct evidence to restore the oceanic evolution, and it is used to identify the convergence boundary of the plates. Compared with ophiolite, ophiolitic mélange, especially its matrix, contains more information about the evolution of ocean. The evolution of eastern Paleo-Tethys, between the South China and Indochina blocks, recorded the whole process of rifting from Gondwana and their northward migration and convergence. To understand the tectonic implications from matrix of ophiolitic mélange, the Mesozoic Paleo-Tethys Ailaoshan–Song Ma–Song Chay suture zone located in the North Vietnam–Southeast Yunnan region acts as an ideal study area. Based on the structural geology, we reviewed previous zircon U-Pb dating and Lu-Hf isotopic analyses on the detrital zircon from the Ailaoshan–Song Ma–Song Chay ophiolitic mélange. Accordingly, we subdivide the matrix of these ophiolitic mélange into four parts (M1, M2, M3, and M4; Fig. 1). M1 is mainly located in the middle segment of the Ailaoshan–Song Ma belt. It shows age peaks of 440 Ma and 960 Ma with εHf(t) values of −19.6 ~ +10.3. M2 is mainly located in the NW segment of the Ailaoshan–Song Ma belt, showing a dominant age peak of ~260 Ma. Particularly, it has εHf(t) values of −28.9 ~ +8.1. M3 is mainly located in the SE segment of the Ailaoshan–Song Ma belt, showing the peaks at ~250 Ma, 440 Ma, and 960 Ma with εHf(t) values of −21.9 ~ +10.1. M4 is mainly located in the Song Chay belt, showing the peaks at ~310 Ma, 470 Ma, 610 Ma, 770 Ma, and 965 Ma with εHf(t) values of −28.2 ~ +10.8. The geochronological data of the detrital zircon from the matrix of the Ailaoshan– Song Ma–Song Chay ophiolitic mélange zone, documents a temporal heterogeneity between the M1, M2, M3, and M4 units, which formed at 310–270 Ma, 265–250 Ma, 245–240 Ma, and 310–255 Ma, respectively. The different components and provenances of each unit reflect a strike-parallel heterogeneity (Fig. 1). The M1 unit was mainly sourced from the Paleozoic sedimentary rocks of the Indochina Block (IB). The main provenance for the M2 unit is Emeishan Large Igneous Province (ELIP). The magmatic arc developed in the IB provided the materials for the M3 unit, and the detrital materials of the M4 were mainly sourced from the South China Block (SCB) (Fig. 1). The Cenozoic strike-slip deformation led to an inverted geometry of the M1, M2, and M3 units, accounting for a strike-perpendicular heterogeneity straight to the strike of the orogenic belt. The temporal, strike-parallel, and strike-perpendicular heterogeneity help us to decipher the tempo-spatial evolution of the Paleo-Tethys. The M1, M2, M3, and M4 units contain information from different evolutionary stages, likely recording the comprehensive history of the ancient oceanic basin. Importantly, our results demonstrate that both the active continental margin of the IB and the passive continental margin of the SCB acted as provenance sources that supplied significant amount of detrital material in the ophiolitic mélange matrix, indicating that the Paleo-Tethys Ocean was a “narrow” or “limited” ocean rather than the archipelagic ocean proposed before.
Źródło:
Geotourism / Geoturystyka; 2023, 1-2 (72-73); 42--43
1731-0830
Pojawia się w:
Geotourism / Geoturystyka
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
COMBINATION OF BERBERINE AND MATRINE AFFECTS APOPTOSIS AND CELLCYCLE IN HUMAN CERVICAL CANCER CELLS
Autorzy:
Zhang, Qijiayu
Sun, Yi
Huang, Yuxi
Sun, Jing
Zhao, Chongbo
Song, Yijun
Wu, Juanhua
Powiązania:
https://bibliotekanauki.pl/articles/895719.pdf
Data publikacji:
2019-12-29
Wydawca:
Polskie Towarzystwo Farmaceutyczne
Tematy:
apoptosis
cervical cancer
Matrine
berberine
Opis:
Cervical cancer is the fourth leading cause of malignancy-related mortality in women worldwide, and effective advanced-stage therapies are urgently required. Berberine is a quaternary ammonium compound extracted from traditional Chinese medicinal herbs, including Phellodendron spp., with antibacterial and antitumor activities. Matrine, the main active ingredient of Sophora flavescens rhizomes, has not only traditionally described health effects but is also widely used for its anticancer, anti-inflammatory, immunoregulatory, antiviral, and hepatoprotective effects. We investigated the antitumor activities of berberine and matrine against human cervical cancer HeLa and SiHa cells using the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay, along with flow cytometry and western blotting analyses, to assess the effect of the compounds on the cellular status and apoptosis- and cell cycle-related proteins. The 24 h half-maximal inhibitory concentrations (IC50) of berberine and matrine were 123.633 ± 4.278 µmol/L and 9.625 ± 0.245 mmol/L against HeLa cells and 105.067 ± 3.745 µmol/L and 8.50 ± 0.23 mmol/L against SiHa cells, respectively. Berberine plus matrine inhibited cancer cell growth and caused cell cycle arrest. We observed an increased stimulation of apoptosis, which was likely mediated by enhanced levels of caspase-3, caspase-9, and B-cell lymphoma 2 (Bcl-2)-associated X protein (Bax), as well as decreased Bcl-2 protein expression. Cell cycle arrest in the G1 phase was probably mediated by p21 upregulation and cyclin-dependent kinase (Cdk)-4, Cdk-6, and cyclin D1 suppression. Combination treatment with berberine and matrine effectively inhibited human cervical cancer cell proliferation, most likely by stimulating apoptosis and inducing cell cycle arrest.
Źródło:
Acta Poloniae Pharmaceutica - Drug Research; 2019, 76, 6; 1089-1097
0001-6837
2353-5288
Pojawia się w:
Acta Poloniae Pharmaceutica - Drug Research
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Increasing nitrogen use efficiency with lower nitrogen application frequencies using zeolite in rice paddy fields
Autorzy:
Wu, Q.
Chen, T.
Chi, D.
Xia, G.
Sun, Y.
Song, Y.
Powiązania:
https://bibliotekanauki.pl/articles/2082479.pdf
Data publikacji:
2019
Wydawca:
Polska Akademia Nauk. Instytut Agrofizyki PAN
Tematy:
available nitrogen
nitrogen uptake
root system
labour force
Opis:
Zeolite can effectively regulate the nutrient status in the root zone of crops, thereby increasing nitrogen utilization. However, there has been relatively little research conducted concerning a possible reduction in the frequency of nitrogen application due to the sustained-release properties of zeolite. In this study, 157.5 kg ha-1 nitrogen in the form of urea fertilizer was applied at the same rate, either as a one-time application or as a 3-way split application with and without 10 t ha-1 zeolite. The effects on rice yield, nitrogen uptake, root morphology and soil properties were evaluated in 2014 and 2015. Results showed that zeolite could enhance the biomass, leaf area index and nitrogen uptake. A higher rice grain yield and nitrogen uptake following soil treatment with zeolite could be attributed to a higher soil cation exchange capacity as well as nitrogen and potassium availability in the soil especially during the vegetative period of the rice plant. The addition of nitrogen to the soil as a one-time application or 3-way split application with 10 t ha-1 zeolite significantly increased rice grain yield by 8.5 or 10.7% compared with nitrogen as a one-time application without zeolite. Zeolite addition greatly improved the development of root morphology and activity compared with treatments without zeolite, which contributed to additional plant growth. The addition of nitrogen to the soil with 10 t ha-1 zeolite as a one-time application that can significantly increase nutrient retention is recommended to improve rice grain yield and decrease nitrogen application frequencies in order to lower both labour forces and energy requirements.
Źródło:
International Agrophysics; 2019, 33, 2; 263-269
0236-8722
Pojawia się w:
International Agrophysics
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Demonstration of a new indicator for studying upwelling in the Northern South China Sea
Autorzy:
Lin, L.
Wang, Y.-S.
Sun, C.-C.
Li, N.
Wang, H.
Mitchell, B.G.
Wu, M.-L.
Song, H.
Wu, J.-F.
Powiązania:
https://bibliotekanauki.pl/articles/48889.pdf
Data publikacji:
2011
Wydawca:
Polska Akademia Nauk. Instytut Oceanologii PAN
Tematy:
China Sea
cluster analysis
multivariate statistical analysis
principal component analysis
remote sensing
satellite monitoring
sea surface temperature
silicate
spatial distribution
upwelling
Opis:
In order to demonstrate that silicate (SiO3-Si) can be used as an indicator to study upwelling in the northern South China Sea, hierarchical cluster analysis (CA) and principle component analysis (PCA) were applied to analyse the metrics of the data consisting of 14 physical-chemical-biological parameters at 32 stations. CA categorized the 32 stations into two groups (low and high nutrient groups). PCA was applied to identify five Principal Components (PCs) explaining 78.65% of the total variance of the original data. PCA found important factors that can describe nutrient sources in estuarine, upwelling, and non-upwelling areas. PC4, representing the upwelling source, is strongly correlated to SiO3-Si. The spatial distribution of silicate from the surface to 200 m depth clearly showed the upwelling regions, which is also supported by satellite observations of sea surface temperature.
Źródło:
Oceanologia; 2011, 53, 2
0078-3234
Pojawia się w:
Oceanologia
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Analysis of the cracking mechanisms in pre-cracked sandstone under radial compression by moment tensor analysis of acoustic emissions
Autorzy:
Wang, Guozhu
Luo, Xulin
Song, Lei
Wang, Yu
Han, Mouwang
Song, Zhaocun
Wu, Linjun
Wang, Zukun
Powiązania:
https://bibliotekanauki.pl/articles/2174031.pdf
Data publikacji:
2022
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
emisja akustyczna
mechanizm pękania
tensor momentu
piaskowiec wstępnie spękany
kompresja promieniowa
acoustic emission
cracking mechanism
moment tensor
pre-cracked sandstone
radial compression
Opis:
Rock masses, especially those with different pre-existing cracks, are prone to instability and failure under tensile loading, resulting in different degrees of engineering disasters. Therefore, to better understand the effect of pre-existing cracks with different dip angles on the tensile instability failure behaviour of rocks, the mechanism of crack initiation, propagation and coalescence in precracked sandstone under radial compression loading is investigated through numerical simulations. The temporal and spatial evolution of acoustic emission (AE) events is investigated by the moment tensor (MT), and the fracture mode of micro-cracks is determined. The results show that the pre-existing cracks weaken the specimens. The strength, crack initiation points and macro-failure modes of the specimens differ significantly depending on the dip angle of the pre-existing crack. For different dip angles of the pre-existing cracks, all the micro-cracks at the crack initiation point are tensile cracks, which are dominant during the whole loading process, and mixed cracks are mainly generated near the upper and lower loading ends after the peak stress. Of the total number of events, more than 75% are tensile cracks; approximately 15% are shear mode cracks; and the remainder consist of mixed mode cracks. The study reveals the instability and failure mechanism of pre-cracked rock, which is of great significance to ensure the long-term stability of rock mass engineering.
Źródło:
Archives of Civil Engineering; 2022, 68, 3; 447--468
1230-2945
Pojawia się w:
Archives of Civil Engineering
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Investigations on the Anisotropic g Factors of the $Ni^{3+}$ Site in $La_2Ni_{0.5}Li_{0.5}O_4$
Autorzy:
Kuang, M.
Wu, S.
Zhang, Z.
Song, B.
Powiązania:
https://bibliotekanauki.pl/articles/1400149.pdf
Data publikacji:
2013-04
Wydawca:
Polska Akademia Nauk. Instytut Fizyki PAN
Tematy:
76.30.Fc
71.70.Ch
75.10.Dg
Opis:
The anisotropic g factors $g_{∥}$ and $g_{⊥}$ of $La_2Ni_{0.5}Li_{0.5}O_4$ are theoretically investigated using the perturbation formulae of the g factors for a low spin $(S=1//2) 3d^7$ ion in tetragonally elongated octahedra. The studied $Ni^{3+} (3d^7)$ center arises from the original $Ni^{2+}$ capturing one hole by $Li^{+}$ doping. The positive anisotropy $\Delta g (= g_{⊥}-g_{∥})$ can be ascribed to the lowest $\text{}^2 A_{1g}$ state due to the obvious (about 0.14 Å) tetragonal elongation of the oxygen octahedron around the $Ni^{3+}$ site via the Jahn-Teller effect, and the effective magnetic moment is also interpreted in a uniform way. The calculated results show good agreement with the experimental data, and the imperfection of the previous studies based on various adjusted tetragonal energy splittings without correlating to the local structure of the magnetic center is thus overcome in this work.
Źródło:
Acta Physica Polonica A; 2013, 123, 4; 734-736
0587-4246
1898-794X
Pojawia się w:
Acta Physica Polonica A
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Fatigue life prediction for Ni-based superalloy GH4169 considering machined surface roughness and residual stress effects
Autorzy:
Wu, Z. R.
Wang, S. Q.
Yang, X.
Pan, L.
Song, Y. D.
Powiązania:
https://bibliotekanauki.pl/articles/1839712.pdf
Data publikacji:
2021
Wydawca:
Polskie Towarzystwo Mechaniki Teoretycznej i Stosowanej
Tematy:
surface roughness
residual stress
fatigue crack
life prediction
GH4169
Opis:
Establishing a fatigue life prediction model considering the machined surface state is of great significance to improve fatigue life prediction accuracy. Fatigue tests with different machined surface states of GH4169 alloy were conducted firstly. The influence of surface state parameters on the fatigue life was analyzed. Then, the machined surface stress concentration factor and residual stress were introduced into the fatigue crack initiation and propagation models. Finally, the fatigue life prediction model of GH4169 material considering the surface states was established. The prediction results based on the proposed model are almost within a factor of two scatter band of the test results.
Źródło:
Journal of Theoretical and Applied Mechanics; 2021, 59, 2; 215-226
1429-2955
Pojawia się w:
Journal of Theoretical and Applied Mechanics
Dostawca treści:
Biblioteka Nauki
Artykuł
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