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    Wyświetlanie 1-8 z 8
    Tytuł:
    Vps41, a protein involved in lysosomal trafficking, interacts with caspase-8
    Autorzy:
    Wang, Lu
    Pan, Xiao
    He, Liangqiang
    Zhang, Rong
    Chen, Wei
    Zhang, Jing
    Lu, Min
    Hua, Zi-Chun
    Powiązania:
    https://bibliotekanauki.pl/articles/1039602.pdf
    Data publikacji:
    2013
    Wydawca:
    Polskie Towarzystwo Biochemiczne
    Tematy:
    caspase-8
    yeast two-hybrid
    Vps41
    protein interaction
    apoptosis
    Opis:
    Caspase-8 is a member of the cysteine-aspartic acid protease (caspase) family which plays a central role in apoptosis and development. We screened caspase-8 interacting proteins from mouse T-cell lymphoma and 7.5-day embryo cDNA libraries by yeast two-hybrid system and obtained eleven positive clones, including Vacuolar protein sorting 41 (Vps41), a protein involved in trafficking of proteins from the late Golgi to the vacuole. The interaction of Vps41 with caspase-8 was confirmed by co-immunoprecipitation (co-IP) and co-localization studies in HEK293T cells. Co-IP experiments also showed that Vps41 binds to the p18 subunit of caspase-8 through its WD40 region and RING-finger motif. Furthermore, we found that overexpression of Vps41 promotes Fas-induced apoptosis in A549 human lung adenocarcinoma cells. The cleavage of caspase-3, a caspase-8 downstream effector, was increased when cells were transfected with Vps41-overexpressing plasmid. Together, these results suggest a novel interaction of caspase-8 with Vps41 and provide a potential role of Vps41 beyond lysosomal trafficking.
    Źródło:
    Acta Biochimica Polonica; 2013, 60, 1; 37-42
    0001-527X
    Pojawia się w:
    Acta Biochimica Polonica
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    The Impacts of Crustacean Zooplankton on a Natural Ciliate Community: a Short-term Incubation Experiment
    Autorzy:
    Li, Jing
    Yang, Kun
    Chen, Feizhou
    Lu, Wenxuan
    Fang, Ting
    Zhao, Xiuxia
    Li, Haiyang
    Cui, Kai
    Powiązania:
    https://bibliotekanauki.pl/articles/52401895.pdf
    Data publikacji:
    2017
    Wydawca:
    Uniwersytet Jagielloński. Wydawnictwo Uniwersytetu Jagiellońskiego
    Tematy:
    ciliates
    small-bodied cladocerans
    pseudodiaptomid copepods
    suppression impacts
    functional groups
    Opis:
    Direct and indirect effects of crustacean zooplankton (cladocerans and copepods) are important regulators of ciliate communities, especially in eutrophic systems. However, it is not clear whether pseudodiaptomids (e.g., Schmackeria), one of the dominant calanoid copepods in Chinese lakes, effectively impacts natural ciliate communities. The impacts of small-bodied cladocerans (e.g., Bosmina) on ciliates are also controversial. We performed an incubation experiment using winter lake water from Lake Chaohu to assess the structuring effects that crustacean zooplankton have on natural ciliate populations. The presence and absence of cladocerans (Bosmina sp.) and copepods (Schmackeria inopinus) were alternated in four treatments. Both Bosmina sp. and Schmackeria inopinus had substantial impacts on ciliate abundance, biomass, and community structure. The response of ciliates was different in the presence of Bosmina sp. compared with Schmackeria inopinus and varied among categories such as the ciliate population, relative body size and functional feeding group. Our results also highlight the importance of interference and exploitative competition among metazooplankton groups.
    Źródło:
    Acta Protozoologica; 2017, 56, 4; 289-301
    0065-1583
    1689-0027
    Pojawia się w:
    Acta Protozoologica
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Personality modifies the effect of post-traumatic stress disorder (PTSD) and society support on depression-anxiety-stress in the residents undergone catastrophic flooding in Henan, China
    Autorzy:
    Jing, Xiangzhi
    Lu, Lingeng
    Yao, Yongcheng
    Powiązania:
    https://bibliotekanauki.pl/articles/2118787.pdf
    Data publikacji:
    2022-09-05
    Wydawca:
    Instytut Medycyny Pracy im. prof. dra Jerzego Nofera w Łodzi
    Tematy:
    PTSD
    personality
    machine learning
    flooding
    society support
    depression-anxiety-stress
    Opis:
    Background: To analyze the impact of the flood disasters, social support and personality on the mental health of residents in Henan Province, China, providing fundamental knowledges for making measuring strategies to improve the psychological protection and anti-stress ability of the residents after the disaster. Material and Methods: A cross-section study was conducted via an online survey platform “questionnaire star,” which included 572 residents in Henan Province, which underwent the history of ever flood disaster on July 20. The questionnaires of Impact of Event Scale-Revised Edition (IES-R), Perceived Social Support Scale (PSSS), the Depression Anxiety Stress Scales (DASS-21) and the scales of Eysenck Personality Questionnaire-Revised (EPQ-R) version in Chinese were also administered to each participant. Generalized linear regression model was performed. Results: The residents who live in the flooding areas, are male and married had a significantly higher post-traumatic stress disorder (PTSD) score than their counterparts. The scores of depression-anxiety-stress in the residents with stable emotion were significantly lower than those with unstable emotion (p < 0.001). Machine learning showed that PTSD ranked the top risk factor, followed by neuroticism for Depression-Anxiety-Stress after disaster. The PTSD was negatively correlated with social support (p < 0.01), while it was positively correlated with depression-anxiety-stress and emotional stability (p < 0.01). There was a statistically significant interaction between PTSD, social support and neuroticism on depression-anxiety-stress (p < 0.001), with an independent effect of 1.4% on depression-anxiety-stress. Emotional stability showed the largest association with depression-anxiety-stress. Conclusions: Residents living in the catastrophic flooding areas had significant post-traumatic mental health issues, and the severity of mental problems was differently affected by post-traumatic stress disorder and social support in individuals with different personalities. Introvert and PTSD were the major risk factors for depression-anxiety-stress after the disaster.
    Źródło:
    Medycyna Pracy; 2022, 73, 4; 305-314
    0465-5893
    2353-1339
    Pojawia się w:
    Medycyna Pracy
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Improvement of leaching efficiency of cathode material of spent $LiNi_xCo_yMn_zO_2$ lithium-ion battery by the in-situ thermal reduction
    Autorzy:
    Lu, Qichang
    Jiang, Haidi
    Xie, Weining
    Zhang, Guangwen
    He, Yaqun
    Duan, Chenlong
    Zhang, Jing
    Yu, Zhaoyi
    Powiązania:
    https://bibliotekanauki.pl/articles/1447956.pdf
    Data publikacji:
    2021
    Wydawca:
    Politechnika Wrocławska. Oficyna Wydawnicza Politechniki Wrocławskiej
    Tematy:
    spent lithium-ion batteries
    in-situ thermal reduction
    leaching efficiency
    LiNixCoyMnzO
    Opis:
    Green cars and electronic products consume lots of lithium-ion batteries (LIBs), and massive spent LIBs are yielded due to performance degradation. This paper provides an economical and environmentally friendly approach to recover valuable metals from cathode materials of the spent LIBs. It combines the in-situ thermal reduction (self-reduction by polyvinylidene fluoride (PVDF) and residual electrolyte in cathode material) and sulfuric acid leaching. Elements of high valent are reduced by the binder (PVDF) and the residual electrolyte on the surface of $NCM(LiNi_xCo_yMn_{1-x-y}O_2)$ material at high temperatures. Moreover, the changes in substance type, element valency, and contents of cathode materials reduced with various terminal temperatures and retention time are analyzed by Xray diffraction (XRD) and X-ray photoelectron spectroscopy (XPS). Results show that the optimal terminal temperature for in-situ thermal reduction is 600 °C, and the optimum retention time is 120 min. Under the best in-situ thermal reduction conditions, the results from XRD confirm that part of $Ni^{2+}$ is converted to simple substance $Ni$, $Co^{3+}$ is reduced to $Co$, and $Mn^{4+}$ is reduced to $Mn^{2+}$ and elemental $Mn$, which are confirmed by XRD. Analyzed results by XPS indicate that the content of $Ni^{2+}$ decreases to 67.05%, and $Co^{3+}$ is completely reduced to $Co$. $Mn^{4+}$ is reduced to 91.41% of $Mn^{2+}$ and 8.59% of simple substance $Mn$. In-situ thermal reduction benefits the leaching processes of cathode materials. The leaching efficiencies of $Ni$, $Co$, and $Mn$ increase from 53.39%, 51.95%, and 0.71% to 99.04%, 96.98%, and 97.52%, respectively.
    Źródło:
    Physicochemical Problems of Mineral Processing; 2021, 57, 2; 70-82
    1643-1049
    2084-4735
    Pojawia się w:
    Physicochemical Problems of Mineral Processing
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Extremal unicyclic graphs with minimal distance spectral radius
    Autorzy:
    Lu, Hongyan
    Luo, Jing
    Zhu, Zhongxun
    Powiązania:
    https://bibliotekanauki.pl/articles/30148716.pdf
    Data publikacji:
    2014-11-01
    Wydawca:
    Uniwersytet Zielonogórski. Wydział Matematyki, Informatyki i Ekonometrii
    Tematy:
    distance matrix
    distance spectral radius
    unicyclic graph
    matching
    Opis:
    The distance spectral radius $ρ(G)$ of a graph $G$ is the largest eigenvalue of the distance matrix $D(G)$. Let $\mathcal{U} (n,m)$ be the class of unicyclic graphs of order $n$ with given matching number $m (m ≠ 3)$. In this paper, we determine the extremal unicyclic graph which has minimal distance spectral radius in $\mathcal{U} (n,m)$ \ $C_n$.
    Źródło:
    Discussiones Mathematicae Graph Theory; 2014, 34, 4; 735-749
    2083-5892
    Pojawia się w:
    Discussiones Mathematicae Graph Theory
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Dioscin improves survival in murine endotoxemia induced by Lipopolysaccharide
    Autorzy:
    Bing, Han
    Jing, Lu
    Meitong, Liu
    Zhe, Feng
    shuang, Guan
    Powiązania:
    https://bibliotekanauki.pl/articles/895519.pdf
    Data publikacji:
    2018-12-31
    Wydawca:
    Polskie Towarzystwo Farmaceutyczne
    Tematy:
    cytokines
    survival
    Endotoxemia
    Dioscin
    NF- қB
    Opis:
    Dioscin is a natural steroidal saponin mainly exacted from Dioscoreae Rhizoma, which usually used as traditional medicine in east asia area. Dioscin has various pharmacological actions. However, little is known concerning the role on Lipopolysaccharide (LPS)-induced endotoxemia. The aim of the present study was to investigate the effects and possible mechanisms of dioscin against LPS-induced endotoxemia in mice. The data showed dioscin significantly increased mouse survival when mice were treated with dioscin prior to or after LPS challenge and significantly attenuated TNF-α, IL-1β and IL-6 production in serum. Further studies revealed that dioscin could downregulate LPS-induced nuclear transcription factor - қB (NF-қB) signal transduction pathways. These observations indicated that dioscin modulated early cytokine responses by blocking NF-қB activation, and thus, increased mouse survival in murine endotoxemia induced by LPS.
    Źródło:
    Acta Poloniae Pharmaceutica - Drug Research; 2018, 75, 6; 1347-1352
    0001-6837
    2353-5288
    Pojawia się w:
    Acta Poloniae Pharmaceutica - Drug Research
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Characterized Microstructure and Electrical Properties of Hydrogenated Nanocrystalline Silicon Films by Raman and Electrical Conductivity Spectra
    Autorzy:
    Xiao-Yong, Gao
    Jian-Tao, Zhao
    Yu-Fen, Liu
    Qing-Geng, Lin
    Yong-Sheng, Chen
    Jin-Hua, Gu
    Shi-E, Yang
    Jing-Xiao, Lu
    Powiązania:
    https://bibliotekanauki.pl/articles/1808127.pdf
    Data publikacji:
    2009-03
    Wydawca:
    Polska Akademia Nauk. Instytut Fizyki PAN
    Tematy:
    71.23.Cq
    73.61.-r
    Opis:
    Microstructure and electrical properties of hydrogenated nanocrystalline silicon (nc-Si:H) film deposited on glass substrate at low temperature were characterized by average grain size, crystallinity, and dark electrical conductivity data obtained from the Raman and electrical conductivity spectroscopy, respectively. The average grain size, crystallinity and electrical conductivity have a similar change with substrate temperature. A threshold substrate temperature determined by silane concentration appears in their corresponding spectroscopy vs. substrate temperature. The dependence of crystallinity, average grain size and electrical conductivity on substrate temperature were accounted for by surface diffusion model and heterojunction quantum dot model, respectively.
    Źródło:
    Acta Physica Polonica A; 2009, 115, 3; 738-741
    0587-4246
    1898-794X
    Pojawia się w:
    Acta Physica Polonica A
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    An empirical examination of the relationship between capability maturity and firm performance across manufacturing and IT industries
    Autorzy:
    Hayes, Louise
    Lu, Jing
    Rezania, Davar
    Powiązania:
    https://bibliotekanauki.pl/articles/2127530.pdf
    Data publikacji:
    2022
    Wydawca:
    Polska Akademia Nauk. Czytelnia Czasopism PAN
    Tematy:
    capability maturity
    quality management
    certification
    maturity model
    Opis:
    We investigate the effect on firm performance of the motivation for applying maturity models in manufacturing and information technology organizations. We expect the association between profitability and maturity models to be less if motivated by external contract requirements (e.g., for certain government contracts), than if motivated internally to improve pro- cesses. Using a sample of firm-year observations for 1,105 SEC registrants in the manufacturing (Standard Industry Classification (SIC): 3600∼3812) and IT industries (SIC: 7370∼7374) for 2017 and 2018, and CMMI information from the CMMI institute published appraisal results system, it is observed that 28 public firms (17 IT firm-years and 23 manufacturing firm-years) in the sample had CMMI appraisals between 2017 and 2018. We use logistic regression to test if the likelihood of CMMI appraisal is positively associated with government sales. The results support for the manufacturing industry, but not for the IT industry, prior research’s assertion that maturity is a source for competitive advantage.
    Źródło:
    Management and Production Engineering Review; 2022, 13, 2; 61--70
    2080-8208
    2082-1344
    Pojawia się w:
    Management and Production Engineering Review
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
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