Wszystkie pola: Crohn’s disease - Katalog OPAC zbiorów

Skocz do pozycji: 1.

Tytuł:: Yersiniosis or Leśniowski-Crohn’s disease
Autorzy:: Franczak, Paula
Witzling, Mieczysław
Siczewski, Wiaczesław
Powiązania:: https://bibliotekanauki.pl/articles/1392537.pdf
Data publikacji:: 2018
Wydawca:: Index Copernicus International
Tematy:: jersiniosis
Leśniowski-Crohn’s disease
Yersinia enterocolitica
Opis:: Yersiniosis is zoonotic disease caused by infection with Yersinia enterocolictica. The variety of clinical signs and the similarity to other diseases causes major diagnostics and therapeutics difficulties. The authors present a case of Yersinia enterocolitica infection in a 38-year-old patient, mimicking Leśniowski Crohn’s disease.
Źródło:: Polish Journal of Surgery; 2018, 90, 1; 52-54
0032-373X
2299-2847
Pojawia się w:: Polish Journal of Surgery
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 2.

Tytuł:: Surgical Cost of Care in Crohn’s Disease
Autorzy:: Keller, Deborah S.
Katz, Jeffry
Stein, Sharon L.
Delaney, Conor P.
Powiązania:: https://bibliotekanauki.pl/articles/1396392.pdf
Data publikacji:: 2013-09-01
Wydawca:: Index Copernicus International
Tematy:: Crohn’s disease
cost of treatment
surgical management
biologic therapy
Opis:: The aim of the studywas to evaluate the cost of surgical care and short-term outcomes of Crohn’s disease(CD) in the era of laparoscopy and biologic therapy. Material and methods. Review of a prospective database identifiedCD patients that underwent surgical management. Patients were stratified into laparoscopic, open, and converted approaches. Main outcome measures were short-term patient outcomes and cost of care by approach. Results. 92 patients were analyzed- 63.1% laparoscopic, 32.6% open, 4.3% converted. The majority was elective (100% converted, 94.8% laparoscopic, 90% open) and segmental resections (75% converted, 70.7% laparoscopic, 43.3% open). Operative times were similar between laparoscopic and open (152 minutes and 138 minutes, respectively). More open patients required ICU care (20% versus 12.1% laparoscopic and 0% converted). The median LOS was 3 (1-25) days laparoscopic, 4 (1-29) open and 4 (3-8) converted. The laparoscopic complication rate was 15.5%, readmission rate 12.1%, and reoperation rate 8.6%. The mean total hospital cost was $9,702 laparoscopic, $10,782 open, and $13,293 for converted cases (US Dollars). Conclusions. Laparoscopy is appropriate for most CD cases. When necessary to combine with open surgery, this results in efficient and effective patient outcomes and healthcare utilization. These results are important when weighing the cost of ongoing medical therapy versus surgical intervention.
Źródło:: Polish Journal of Surgery; 2013, 85, 9; 511-516
0032-373X
2299-2847
Pojawia się w:: Polish Journal of Surgery
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 3.

Tytuł:: Selected morphotic parameters differentiating ulcerative colitis from Crohn’s disease
Autorzy:: Kasperczuk, Anna
Powiązania:: https://bibliotekanauki.pl/articles/2112830.pdf
Data publikacji:: 2021
Wydawca:: Politechnika Białostocka. Oficyna Wydawnicza Politechniki Białostockiej
Tematy:: action rules
data mining
colon disease
morphotic parameters
smoking
Opis:: This paper presents a method that binds statistical and data mining techniques, which aims to support the decision-making process in selected diseases of the digestive system. Currently, there is no precise diagnosis for ulcerative colitis (UC) and Crohn's disease (CD). Specialist physicians must exclude many other diseases occurring in the colon. The first goal of this study is a retrospective analysis of medical data of patients hospitalised in the Department of Gastroenterology and Internal Diseases, Bialystok, and finding the symptoms differentiating the two analysed diseases. The second goal is to build a system that clearly points to one of the two diseases UC or CD, which shortens the time of diagnosis and facilitates the future treatment of patients. The work focuses on building a model that can be the basis for the construction of action rules, which are one of the basic elements in the medical recommendation system. Generated action rules indicated differentiating factors, such as mean corpuscular volume, platelets (PLTs), neutrophils, monocytes, eosinophils, basophils, alanine aminotransferase (ALAT), creatinine, sodium and potassium. Other important parameters were smoking and blood in stool.
Źródło:: Acta Mechanica et Automatica; 2021, 15, 4; 249--253
1898-4088
2300-5319
Pojawia się w:: Acta Mechanica et Automatica
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 4.

Tytuł:: Decision-making process in colon disease and crohn’s disease treatment
Autorzy:: Dardzińska, A.
Kasperczuk, A.
Powiązania:: https://bibliotekanauki.pl/articles/970573.pdf
Data publikacji:: 2018
Wydawca:: Politechnika Białostocka. Oficyna Wydawnicza Politechniki Białostockiej
Tematy:: colon disease
logistic regression
decision system
information system
Opis:: The article presents the process of building a logistic regression model, which aims to support the decision-making process in medicine. Currently, there is no precise diagnosis for ulcerative colitis (UC) and Crohn's disease (CD). Specialist physicians must exclude many other diseases occurring in the colon. The first goal of this study is a retrospective analysis of medical data of patients hospitalized in the Department of Gastroenterology and Internal Diseases and finding the symptoms differentiating the two analyzed diseases. The second goal is to build a system that clearly points to UC or CD, which shortens the time of diagnosis and facilitates the treatment of patients. The work focuses on building a model that can be the basis for the construction of classifiers, which are one of the basic elements in the medical recommendation system. The developed logistic regression model will define the probability of the disease and will indicate the statistically significant changes that affect the onset of the disease. The value of probability will be one of the main reasons for the decision.
Źródło:: Acta Mechanica et Automatica; 2018, 12, 3; 227-231
1898-4088
2300-5319
Pojawia się w:: Acta Mechanica et Automatica
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 5.

Tytuł:: Choroba Leśniowskiego-Crohna – diagnostyka i leczenie
Crohn’s disease – diagnosis and treatment
Autorzy:: Hebzda, Andrzej
Szczeblowska, Dorota
Serwin, Dariusz
Wojtuń, Stanisław
Hebzda, Zbigniew
Grys, Iwona
Powiązania:: https://bibliotekanauki.pl/articles/1031708.pdf
Data publikacji:: 2011
Wydawca:: Medical Communications
Tematy:: Crohn’s disease
biological treatment
extraintestinal manifestations
immunomodulators
immunomodulatory
steroid treatment
choroba leśniowskiego-crohna
leczenie biologiczne
powikłania
pozajelitowe
sterydoterapia
Opis:: Crohn’s disease is a chronic disease that may occur in any part of digestive tract, causing significant lowering of quality of life and declining of fitness of patients. Most common symptoms are: abdominal pain, diarrhoea, blood in stool, palpable (often tender) mass in abdomen, weight loss, weakness, fever and feverishness. Those symptoms are often accompanied by perianal lesions such as fistulae, fissures and abscesses, and also other enterocutaneous fistulae. Diagnosis is based on endoscopy with biopsies, histopathology and radiological techniques with use of barium contrast. In spite of improving recognition of Crohn’s disease and better accessibility to diagnostic procedures some cases are diagnosed during surgery because of ileus or wrong diagnosis of appendicitis. Typical treatment includes 5-aminosalicilates, glicocorticoids and thiopurines. At the moment there are two monoclonal anti-TNF-α antibodies registered in Poland for biological treatment of Crohn’s disease. Conventional and biological therapy doesn’t always allow us to prevent surgical treatment. In years of observation, most of the patients undergo at least one surgery. Recent publication demonstrate purposefulness of early biologic and immunosuppressive therapy (top-down strategy). The chance to change course of disease is tempting, but possibility of complications (esp. infectious) suggest cautious approach, until further data are known. Those complications also incline us to leave this kind of treatment to experienced sites.
Choroba Leśniowskiego-Crohna jest przewlekłym schorzeniem, które może dotyczyć dowolnego odcinka przewodu pokarmowego (najczęściej końcowego odcinka jelita cienkiego), powodującym znaczne obniżenie jakości życia oraz upośledzenie sprawności chorego. Najczęstsze objawy to ból brzucha, biegunka, krew w stolcu, badalny (często tkliwy) opór w jamie brzusznej, utrata masy ciała, osłabienie, stany podgorączkowe i gorączka. Często towarzyszą im zmiany okolicy odbytowej – przetoki, szczeliny i ropnie, a także przetoki jelitowo-skórne. Rozpoznanie opiera się na endoskopii z pobraniem wycinków, histopatologii oraz metodach radiologicznych z użyciem kontrastu. Pomimo coraz lepszego rozpoznawania i łatwiejszego dostępu do diagnostyki część przypadków jest diagnozowana w trakcie zabiegu z powodu niedrożności lub mylnie rozpoznanego zapalenia wyrostka robaczkowego. W leczeniu najczęściej stosuje się preparaty 5-aminosalicylanów, glikokortykosteroidy oraz tiopuryny. Obecnie w Polsce zarejestrowane są dwa przeciwciała anty-TNF-α, stosowane w terapii biologicznej. Leczenie metodami klasycznymi oraz lekami biologicznymi nie zawsze pozwala uniknąć interwencji chirurgicznej. Z dłuższej obserwacji wynika, że większość chorych przechodzi przynajmniej jeden zabieg operacyjny. Nowe doniesienia coraz śmielej wskazują na celowość wczesnego włączania terapii biologicznej i immunosupresyjnej (strategia top-down). Choć szansa zmiany przebiegu choroby w wyniku agresywnego leczenia od momentu rozpoznania jest kusząca, ze względu na możliwość wystąpienia powikłań takiej terapii, zwłaszcza infekcyjnych, należy zachować ostrożność, dopóki nie będziemy mieli więcej danych. Powikłania te wymuszają również, aby leczeniem tym zajmowały się ośrodki referencyjne, mające duże doświadczenie w tej dziedzinie.
Źródło:: Pediatria i Medycyna Rodzinna; 2011, 7, 2; 98-103
1734-1531
2451-0742
Pojawia się w:: Pediatria i Medycyna Rodzinna
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 6.

Tytuł:: Laparoscopically Assisted Ileo-Colonic Resection in Patients with Crohn’s Disease – Preliminary Report
Autorzy:: Borycka-Kiciak, Katarzyna
Dib, Naser
Janaszek, Łukasz
Sołtysiak, Łukasz
Bukowicka, Barbara
Tarnowski, Wiesław
Powiązania:: https://bibliotekanauki.pl/articles/1396388.pdf
Data publikacji:: 2013-09-01
Wydawca:: Index Copernicus International
Tematy:: laparoscopy
Crohn’s disease
postoperative complications
Opis:: Despite increasing number of reports indicating good treatment outcomes, laparoscopic treatment of Crohn’s disease remains controversial. The aim of the study was to compare outcomes of laparoscopically assisted and open ileo-colonic resection in patients with active Crohn’s disease. Material and methods. 82 patients who underwent surgical treatment (44 laparoscopic and 38 open procedures) at the Department of General, Oncological and Gastrointestinal Surgery in Warsaw were enrolled to the study. The following perioperative parameters were compared in both these groups: duration of hospitalization and presence of postoperative complications in at least 12 months of follow‑up. Results. The conversion rate in the laparoscopy group was 29.5%. There were no statistically significant differences between the study groups with regard to duration of the surgical procedure, requirement for perioperative transfusions and total number of postoperative complications (19.3% in the laparoscopy group versus 28.9% in the open surgery group). However, amount of analgesic drugs required in the postoperative period was significantly lower (25±6 vs 43±9, p<0.01) and duration of hospitalization was significantly shorter (9.0 vs 11.3 days, p=0.021) after laparoscopic versus open procedures procedures. Most of the patients with complicated Crohn’s disease who were qualified to laparoscopic treatment, underwent successful treatment using this method. Patients in whom conversion was done, were more likely to be on long term preoperative immunosuppressive therapy versus other patients. Conclusions. Laparoscopy is a demanding procedure from the technical point of view, but provides valuable benefits to patients with Crohn’s disease, including those with a complicated disease. However, this method requires ongoing improvement of technical aspects and thorough analysis of failures to identify factors that could accurately select patients with indications and contraindications to this procedure.
Źródło:: Polish Journal of Surgery; 2013, 85, 9; 505-510
0032-373X
2299-2847
Pojawia się w:: Polish Journal of Surgery
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 7.

Tytuł:: Impact of biological treatment on intestinal microbiom in children with Crohn’s disease
Autorzy:: Krawczyk, Agnieszka
Sroka-Oleksiak, Agnieszka
Kowalska-Duplaga, Kinga
Fyderek, Krzysztof
Gosiewski, Tomasz
Salamon, Dominika
Powiązania:: https://bibliotekanauki.pl/articles/1177355.pdf
Data publikacji:: 2018
Wydawca:: Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
Tematy:: Crohn’s disease
biological treatment
children
gut microbiota
Opis:: Crohn’s disease (CD) is a chronic, inflammatory illness of the digestive tract, characterized by alternating periods of remission and recurrence. The pathogenesis of CD is still unclear but probably is a result of a complex interaction between immunological, genetic and microbiological disorders. In recent years, there has been an increasing extent of evidence that gut microbiota plays a very important role in the pathogenesis of CD. Currently, the most effective treatment is biological therapy using anti-TNF monoclonal antibodies. It is interesting whether biological drugs resulting in fast remission, contributes to the normalization of the gut microbiota. Due to the fact that the children’s population is a significant percentage of all patients with CD, it is important to pay close attention to the problem of microbiological disorders in this age group. The aim of this study was to investigate whether there are quantitative changes of chosen bacteria species and fungi of the genus Candida in children with Crohn's disease relative to healthy children and assesment of quantitative changes in patients after biological treatment. In the group of children with Crohn’s disease, the numbers in Candida were significantly higher (9.74×1017 CFU/g) than in the control group (9.35×1010 CFU/g, p = 0.011). Biological therapy led to a significant reduction in the amount Candida (5.91×1011) and was comparable with the number in the control group. In the case of bacteria, we observed an increase in S. marcescens (3,4×108) in the patients group compared to the controls (1,85×108) and an increase in L. fermentum (2,34×1010) in relation to healthy children (3,31×108, p = 0,048) Biological treatment had an impact on the decrease in L. fermentum (4,76×109, p = 0.05).
Źródło:: World Scientific News; 2018, 104; 245-256
2392-2192
Pojawia się w:: World Scientific News
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 8.

Tytuł:: All that fistulises is not Crohn’s disease: Multiple entero-enteric fistulae in intestinal tuberculosis
Autorzy:: Singh, Harjeet
Mandavdhare, Harshal
Sharma, Vishal
Powiązania:: https://bibliotekanauki.pl/articles/1392382.pdf
Data publikacji:: 2019
Wydawca:: Index Copernicus International
Tematy:: intestinal tuberculosis
crohn’s disease
fistula
intestinal obstruction
surgery
Opis:: Abdominal tuberculosis is a common problem for clinicians in the tropical world and may manifest with varying clinical scenarios. Intestinal tuberculosis could have intestinal ulcers, strictures, hypertrophic lesions like polyps and may be complicated by perforation, bleeding, and intestinal obstruction. Crohn’s disease is an important differential of intestinal tuberculosis which is closely mimics intestinal tuberculosis in clinical, endoscopic, radiological and histological presentation. Crohn’s disease is known to have a fistulising variant. We report the case of 23 year old lady who had disseminated tuberculosis with intestinal involvement and seemed to improve on anti-tubercular therapy (ATT) but present with intestinal obstruction in the third month of ATT. Surgical exploration revealed clumping of bowel loops with multiple ileo-ileal fistulae. The case is presented because of the presence of entero-enteric fistulae and also because it demonstrated that intestinal tuberculosis may need surgical intervention even after initial improvement because of complications like intestinal obstruction.
Źródło:: Polish Journal of Surgery; 2019, 91, 1; 35-37
0032-373X
2299-2847
Pojawia się w:: Polish Journal of Surgery
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 9.

Tytuł:: Analysis of factors affecting the quality of life of those suffering from Crohn’s disease
Autorzy:: Chrobak-Bień, Joanna
Gawor, Anna
Paplaczyk, Małgorzata
Małecka-Panas, Ewa
Gąsiorowska, Anita
Powiązania:: https://bibliotekanauki.pl/articles/1392978.pdf
Data publikacji:: 2017
Wydawca:: Index Copernicus International
Tematy:: quality of life
Crohn’s disease
disease activity
Opis:: Introduction. Crohn’s disease is an inflammatory bowel disease of unknown etiology. Its chronic nature, as well as symptoms of intestinal and overall significantly impedes the daily functioning of patients. Alternately occurring periods of exacerbation and remission are the cause of reduced quality of life of patients. Understanding the factors that caused the decrease in the quality of life, it allows us to understand the behavior and the situation of the patient and the ability to cope with stress caused by the disease. Aim of the study. The aim of the study was to analyze the factors affecting the quality of life of people with Crohn’s disease. Material and methods. The study group consisted of 50 people diagnosed with Crohn’s disease. Respondents were treated at the Department of General Surgery and Colorectal Medical University of Lodz and Gastroenterological Clinic at the University Clinical Hospital No. 1 in Lodz. Quality of Life Survey was carried out by a diagnostic survey using a research tool SF-36v2 and surveys of its own design. Results. Analysis of the results demonstrated that the quality of life of patients with Crohn’s disease was reduced, especially during exacerbations. Evaluation of the quality of life of respondents in physical terms was slightly higher than in the mental aspect. Higher education subjects and the lack of need for surgical treatment significantly improves the quality of life. Conclusions. The occurrence of chronic disease reduces the quality of life of respondents. Elderly patients are better able to adapt to the difficult situation caused by the disease. The quality of life of women and men is at a similar level and patients in remission of the disease have a better quality of life of patients during exacerbations.
Źródło:: Polish Journal of Surgery; 2017, 89, 4; 16-22
0032-373X
2299-2847
Pojawia się w:: Polish Journal of Surgery
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 10.

Tytuł:: Jakość życia młodzieży z chorobą Leśniowskiego-Crohna
Quality of life in adolescents with Crohn’s disease
Autorzy:: Cepuch, Grażyna
Gniadek, Agnieszka
Śręba, Sabina
Powiązania:: https://bibliotekanauki.pl/articles/1196840.pdf
Data publikacji:: 2015
Wydawca:: Instytut Medycyny Wsi
Opis:: Wstęp. Choroba Leśniowskiego-Crohna, z uwagi na swój charakter i specyfikę, obejmuje wiele płaszczyzn życia młodzieży, determinując jego jakość w sposób bezpośredni, jak i pośredni. Samopoczucie i dobre funkcjonowanie fizyczne i społeczne młodego pacjenta, a zatem jego jakość życia, wpływa na skuteczną kontrolę przebiegu choroby. Cel pracy. Ocena jakości życia młodzieży z chorobą Leśniowskiego-Crohna. Materiał i metody. W badaniu uczestniczyło 61pacjentów obojga płci, w wieku 13–18 lat, z rozpoznaną chorobą Leśniowskiego-Crohna, hospitalizowanych z powodu wykonania kontrolnych badań diagnostycznych, zaostrzeń choroby lub podania leku biologicznego. W badaniu zastosowano metodę sondażu diagnostycznego, wykorzystując standaryzowany kwestionariusz ankiety WHOQOL – BREF, drabinę Cantrila i autorski kwestionariusz ankiety. Weryfikacji różnic między zmiennymi dokonano przy użyciu testu niezależności Chi2, testu t dla prób zależnych i niezależnych, korelacji rho Spearmana oraz testu zgodności Chi2. Za poziom istotności przyjęto p< 0,05. Wyniki. Pacjenci, pomimo występowania u nich dolegliwości związanych z chorobą i wpływu choroby na ich życie, oceniają swoją jakość życia jako zadowalającą ich. Również znaczny odsetek pacjentów deklaruje zadowolenie ze swojego stanu zdrowia. Wykazano istotną statystycznie zależność pomiędzy wiekiem badanych a jakością życia, w szczególności w dziedzinie relacje społeczne – wsparcie społeczne, dziedzinie fizycznej oraz środowiska. Młodzież wysoko oceniła swoją jakość życia w ocenie bieżącej, jak i przewidywanej. Wnioski. Młodzież wykazuje zadowolenie ze swojego codziennego funkcjonowania pod względem biopsychospołecznym, co może być związane z rozumieniem swojej choroby oraz otrzymywanym wsparciem. Kluczowa w podnoszeniu jakości życia młodych pacjentów z L-C jest szeroko zakrojona edukacja dotycząca schorzenia i radzenia sobie z nią oraz umiejętne udzielanie wsparcia w chorobie.
Introduction. Leśniowski-Crohn’s disease, because of its nature and character, affects many spheres in the life of a young person, and determines the quality of life. Wellbeing and good physical and social functioning of adolescent patients, thus their quality of life, are responsible for an effective control over the course of the disease. Objective. Evaluation of the quality of life of adolescent patients suffering from Crohn’s disease. Material and methods. The study covered 61 male and female patients aged 13–18, diagnosed with Leśniowski-Crohn’s disease, who were hospitalized to perform diagnostic check-up tests, due to aggravation of the disease or for administration of biological therapy. The study was performed by the method of a diagnostic survey, using a standardized WHOQOL – BREF questionnaire, the Cantril’s ladder, and a questionnaire designed by the author. The differences between variables were verified using the Chi2 test of independence, T-test for dependent and independent samples, Spearman’s rank correlation and chi square goodness of fit test. The p level p< 0.05 was considered statistically significant. Results. Despite discomfort caused by the disease and its influence on everyday routine, the patients evaluated their quality of life as satisfactory. A considerable percentage of patients were satisfied with their health condition. A statistically significant relationship was observed between the age of the patients and their quality of life, especially in the sphere of Social Relations – social support, and Physical and Environmental spheres. The adolescents evaluated their quality of life, both current and expected, in high terms. Conclusions. Adolescents were satisfied with their daily life functioning from the bio-psycho-social aspect, which may be related with the understanding of own disease and the support obtained. An extensive education concerning the disease and coping with it, as well as skilful provision of support play the key role in the improvement of the quality of life of patients with Crohn’s disease.
Źródło:: Medycyna Ogólna i Nauki o Zdrowiu; 2015, 21(50), 4
2083-4543
Pojawia się w:: Medycyna Ogólna i Nauki o Zdrowiu
Dostawca treści:: Biblioteka Nauki

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