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Wyszukujesz frazę "hydrophilic gels" wg kryterium: Temat

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    Wyświetlanie 1-6 z 6
    Tytuł:
    Research of pharmaceutical properties of hydrophilic powders containing lactic acid complexed with chitosan
    Autorzy:
    Małolepsza-Jarmołowska, Katarzyna
    Powiązania:
    https://bibliotekanauki.pl/articles/1035180.pdf
    Data publikacji:
    2014
    Wydawca:
    Sieć Badawcza Łukasiewicz - Polskie Towarzystwo Chitynowe
    Tematy:
    anti-inflammatory drugs
    hydrophilic powders passing gels
    lactic acid complexed with chitosan
    physiological environment of vagina
    vaginal infections
    vaginal mucosa
    Opis:
    Hydrophilic powders passing gels containing lactic acid complexed with chitosan at a stoichiometric ratio of 1:1 and 8:1 revealed pH ranged from 3.92 to 4.44 and 2.36 to 2.84. Rheological studies demonstrated that the research gels obtained from powders possess the dynamic viscosity ranging from 53 to 398 mPa.s for the 1:1 stoichiometric ratio in the complex and from 19 to 242 mPa.s for the 8:1 ratio. As a result of the research, preparations with different pH values, including physiological range, were obtained. Powders show that the adhesion of the gel covering the surface of the apparatus simulates the conditions in the vagina. The gels obtained from the powders were characterised by the specific dynamic viscosity and possess the work of adhesion. The results obtained in the experimental studies proved that it is possible to produce a preparation with optimal pharmaceutical and application properties.
    Źródło:
    Progress on Chemistry and Application of Chitin and its Derivatives; 2014, 19; 79-85
    1896-5644
    Pojawia się w:
    Progress on Chemistry and Application of Chitin and its Derivatives
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Pharmaceutical assessment of gynaecological powders with the addition of hydrophilising substances containing lactic acid complexed with chitosan
    Autorzy:
    Małolepsza-Jarmołowska, Katarzyna
    Powiązania:
    https://bibliotekanauki.pl/articles/1035187.pdf
    Data publikacji:
    2014
    Wydawca:
    Sieć Badawcza Łukasiewicz - Polskie Towarzystwo Chitynowe
    Tematy:
    anti-inflammatory drugs
    hydrophilic powders passing gels
    lactic acid complexed with chitosan
    physiological environment of vagina
    vaginal infections
    vaginal mucosa
    Opis:
    Research on gynaecological preparations followed that of optimising their pharmaceutical properties, which is beneficial for gynaecological powders. Gels obtained from powders containing lactic acid complexed with chitosan revealed a stoichiometric ratio 1:1, 2;1, 3:1, 4:1 and 8:1. Their pH ranged from 3.92 to 4.44 for 1:1 gels and from 2.36 to 2.84 for the 8:1 ratio. The addition of 5% polyethylene glycol-400 increases the pH from 4.52 to 4.92 for 1:1 gels and from 2.54 to 3.41 for the 8:1 ratio. A modification of the composition of the tested powders containing 5% polyethylene glycol-400 increased the range of the dynamic viscosity of formulations suitably from 78 to 520 mPa.s for 1:1 gels and from 39 to 423 mPa.s for the 8:1 ratio. Measurements performed in a biopharmaceutical model revealed that the gels obtained from powders containing lactic acid complexed with chitosan are able to move from 25 to 28 cm.
    Źródło:
    Progress on Chemistry and Application of Chitin and its Derivatives; 2014, 19; 95-101
    1896-5644
    Pojawia się w:
    Progress on Chemistry and Application of Chitin and its Derivatives
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    The properties of thermosensitive gynecological powders containing lactic acid complexed with chitosan
    Autorzy:
    Małolepsza-Jarmołowska, Katarzyna
    Powiązania:
    https://bibliotekanauki.pl/articles/1034802.pdf
    Data publikacji:
    2015
    Wydawca:
    Sieć Badawcza Łukasiewicz - Polskie Towarzystwo Chitynowe
    Tematy:
    anti-inflammatory drugs
    lactic acid complexed with chitosan
    physiological environment of vagina
    thermosensitive hydrophilic powders passing gels
    vaginal infections
    vaginal mucosa
    Opis:
    The investigations showed that the addition of a 20%, 23% and 25% poloxamer 407 increases the adhesive properties of the investigated powders, but at the same time it increases their pH. The enrichment of the composition of the tested powders containing 5% glycerol and 5% 1,2-propylene glycol resulted in increased pH of the formulations. A modification of the composition of the tested powders containing 5% glycerol and 5% 1,2-propylene glycol has increased the range of the dynamic viscosity of formulations. The enrichment of the composition of the tested powders containing 5% hydroxypropylmethylcellulose resulted in increased the range of the dynamic viscosity and decreased pH of the formulations. Laboratory tests have shown that it is possible to obtain thermosensitive gels with high adhesion properties to vaginal mucous membrane.
    Źródło:
    Progress on Chemistry and Application of Chitin and its Derivatives; 2015, 20; 183-194
    1896-5644
    Pojawia się w:
    Progress on Chemistry and Application of Chitin and its Derivatives
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Influence of a chosen auxiliary substance on the properties of hydrophilic powders containing lactic acid complexed with chitosan
    Autorzy:
    Małolepsza-Jarmołowska, Katarzyna
    Powiązania:
    https://bibliotekanauki.pl/articles/1035192.pdf
    Data publikacji:
    2014
    Wydawca:
    Sieć Badawcza Łukasiewicz - Polskie Towarzystwo Chitynowe
    Tematy:
    anti-inflammatory drugs
    hydrophilic powders passing gels
    lactic acid complexed with chitosan
    physiological environment of vagina
    vaginal infections
    vaginal mucosa
    Opis:
    Hydrophilic powders passing gels containing lactic acid complexed with chitosan at a stoichiometric ratio of 1:1 and 8:1 revealed pH ranged from 3.92 to 4.44 and 2.36 to 2.84. Rheological studies demonstrated that the research gels obtained from powders possess the dynamic viscosity ranging from 53 to 398 mPa.s for the 1:1 stoichiometric ratio in the complex and from 19 to 242 mPa.s for the 8:1 ratio. As a result of the research, preparations with different pH values, including physiological range, were obtained. Powders show that the adhesion of the gel covering the surface of the apparatus simulates the conditions in the vagina. The gels obtained from the powders were characterised by the specific dynamic viscosity and possess the work of adhesion. The results obtained in the experimental studies proved that it is possible to produce a preparation with optimal pharmaceutical and application properties.
    Źródło:
    Progress on Chemistry and Application of Chitin and its Derivatives; 2014, 19; 87-93
    1896-5644
    Pojawia się w:
    Progress on Chemistry and Application of Chitin and its Derivatives
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Use polyvinylpyrrolidone in technology of gynaecological powders containing lactic acid complexed with chitosan
    Autorzy:
    Małolepsza-Jarmołowska, Katarzyna
    Powiązania:
    https://bibliotekanauki.pl/articles/1035193.pdf
    Data publikacji:
    2014
    Wydawca:
    Sieć Badawcza Łukasiewicz - Polskie Towarzystwo Chitynowe
    Tematy:
    anti-inflammatory drugs
    hydrophilic powders passing gels
    lactic acid complexed with chitosan
    physiological environment of vagina
    vaginal infections.
    vaginal mucosa
    Opis:
    metric ratio of 1:1, 2:1, 3:1, 4:1 and 8:1. Their pH ranged from 3.92 to 4.44 for 1:1 gels and from 2.36 to 2.84 for the 8:1 ratio. The addition of 5% polyvinylpyrrolidone K-90 increased the pH from 4.28 to 4.52 for 1:1 and from 2.58 to 3.30 for the 8:1 ratio. The addition of 5% polyvinylpyrrolidone K-90 increased the dynamic viscosity from 84 to 510 mPa.s for 1:1 gels and from 47 to 386 mPa.s for the 8:1 ratio. The gels obtained from powders possess the work of adhesion - the energy needed to separate the gel from the probe was 15.2 g/s for gels with 5% polyvinylpyrrolidone K-15, 52.76 g/s for gels with 5% polyvinylpyrrolidone K-30, and 56.6 g/s for gels containing 5% polyvinylpyrrolidone K-90. The results proved that it is possible to produce a preparation with optimal pharmaceutical and application properties.
    Źródło:
    Progress on Chemistry and Application of Chitin and its Derivatives; 2014, 19; 103-110
    1896-5644
    Pojawia się w:
    Progress on Chemistry and Application of Chitin and its Derivatives
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Influence of hydrophilic polymers on the properties of gynecological powders containing lactic acid complexed with chitosan
    Autorzy:
    Małolepsza-Jarmołowska, Katarzyna
    Powiązania:
    https://bibliotekanauki.pl/articles/1034997.pdf
    Data publikacji:
    2015
    Wydawca:
    Sieć Badawcza Łukasiewicz - Polskie Towarzystwo Chitynowe
    Tematy:
    anti-inflammatory drugs
    lactic acid complexed with chitosan
    physiological environment of vagina
    thermosensitive hydrophilic powders passing gels
    vaginal infections
    vaginal mucosa
    Opis:
    Tested impact of polyvinyl alcohol, dextrane and calcium alginate for the properties of the powders containing poloxamer 407 and lactic acid complexed with chitosan. For researches was prepared formulations with different pH and rheological properties. The thermosensitive gels obtained from thermosensitive powders possess the work of adhesion with different values. The researches revealed that the dynamic viscosity of the gels obtained from powders is high. A wide range of pH of the thermosensitive gels allows the selection of the optimum formulation. The gels obtained from the powders containing polyvinyl alcohol or dextrane or calcium alginate were characterized by the specific dynamic viscosity. The researches demonstrated that the methylcellulose with different values of the viscosity with poloxamer 407 significantly affect the adhesive properties of thermosensitive hydrophilic gels obtained from powders.
    Źródło:
    Progress on Chemistry and Application of Chitin and its Derivatives; 2015, 20; 195-203
    1896-5644
    Pojawia się w:
    Progress on Chemistry and Application of Chitin and its Derivatives
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
      Wyświetlanie 1-6 z 6

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