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    Wyświetlanie 1-8 z 8
    Tytuł:
    Ovarian cancer and inflammation. Part 2. Anti-inflammatory cytokines
    Autorzy:
    Terlikowska, K.M.
    Dobrzycka, B.
    Terlikowski, S.J.
    Powiązania:
    https://bibliotekanauki.pl/articles/1918736.pdf
    Data publikacji:
    2018
    Wydawca:
    Uniwersytet Medyczny w Białymstoku
    Tematy:
    Ovarian cancer
    inflammation
    cytokines
    Opis:
    Inflammation plays a key role in epithelial ovarian cancer tumorigenesis and progression. The growth and progression of epithelial ovarian cancer may be due to local cytokine-induced immunosu-ppression, which may lead to an immunity impairment. Thus, cytokine antagonism may be an essential factor in the treatment of ovarian cancer. Based on the increased knowledge on the role of the immune system in ovarian cancer, major improvements are to be expected of immunotherapy based treatment of this disease. This article aims to summarize the current literature views on the evidence for a role for chronic inflammation with a specific focus on anti-inflammatory cytokines.
    Źródło:
    Progress in Health Sciences; 2018, 8(2); 206-209
    2083-1617
    Pojawia się w:
    Progress in Health Sciences
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Nutrigenomics – a new approach for cancer prevention and treatment
    Autorzy:
    Piątek, W.
    Milewska, M.
    Krasowska, U.
    Terlikowska, K.M.
    Powiązania:
    https://bibliotekanauki.pl/articles/1918602.pdf
    Data publikacji:
    2018-06-18
    Wydawca:
    Uniwersytet Medyczny w Białymstoku
    Tematy:
    Bioactive food compounds
    cancer
    treatment
    prevention
    Opis:
    Diet is a major environmental factor which maintains metabolic balance and body homeostasis. The aim of the study was to present the latest reports on the biological activity of the food compounds in a critical review. It has been shown that bioactive substances supplied with food e.g. polyphenols, flavonoids or phenolic acids exhibit immunomodulatory and anti-inflammatory fun-ctions. What is more, they favourably downregulate major oncogenes and enhance suppressors’ expression. Studies show that these substances can be an important component of cancer prevention and treatment. However, there are micronutrients like iron or copper which elevated levels in cancer cells occurs and should be considered as a therapeutic targets.
    Źródło:
    Progress in Health Sciences; 2018, 8(1); 151-157
    2083-1617
    Pojawia się w:
    Progress in Health Sciences
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Polyphenols and flavonoids in the prevention and treatment of diabetes type 2
    Autorzy:
    Wałkuski, M.
    Szwed, O.
    Lendzioszek, M.
    Terlikowska, K.M.
    Powiązania:
    https://bibliotekanauki.pl/articles/1918750.pdf
    Data publikacji:
    2018
    Wydawca:
    Uniwersytet Medyczny w Białymstoku
    Tematy:
    Diabetes
    diet
    food
    polyphenols
    flavonoids
    genes
    alleles
    Opis:
    The genetic basis of diabetes is associated with genes that predispose to obesity development. There are also variants of genes that change the metabolism and distribution of glucose in the body tissues. Others regulate the lipid profile or affect insulin resistance, directly or indirectly affecting the risk of developing diabetes. Polyphenols are a group of compounds that have a protective effect on pancreatic cells. Thanks to their antioxidant activity, they protect cells against apoptosis, improve glucose metabolism and reduce hyperglycemia. The aim of the review was to discuss the mechanisms of bioactive food compounds influence on the human genome and to demonstrate their relationship between diabetes prevention and treatment.
    Źródło:
    Progress in Health Sciences; 2018, 8(2); 174-180
    2083-1617
    Pojawia się w:
    Progress in Health Sciences
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    The influence of carotenoid and chlorophyll content on the oxidative processes in the selected vegetable oils
    Autorzy:
    Mahoney, E.Y.
    Milewska, M.
    Mironczuk-Chodakowska, I.
    Terlikowska, K.M.
    Powiązania:
    https://bibliotekanauki.pl/articles/1918745.pdf
    Data publikacji:
    2018
    Wydawca:
    Uniwersytet Medyczny w Białymstoku
    Tematy:
    Vegetable oils
    total colour
    acid number
    peroxide number
    Opis:
    Purpose: More than 100 plant species have been classified as oil products, but only a few of them are used in industrial production. In the available literature, there are no studies that would describe the relationship between the content of plant dyes and their impact on auto-oxidative processes. Therefore, this study aimed to determine dye composition and to define their effect on the acid value, peroxide value and quality assessment of selected refined and unrefined oils. Materials and methods: Twenty samples from different manufacturers were evaluated. Oils were purchased from retail trade of the Bialystok city. The total colour, acid, and peroxide values were determined in accordance with the Polish Standards PN-ISO 3960: 1996, PN-A-86934: 1995 and PN-ISO 3960: 1996, respectively. Results: Statistically significant differences of total colour values between both groups were found (p=0.002). The acid value of refined oils was lower than in an unrefined group (p=0.02). A positive statistically significant correlation was noticed between the total colour value and the acid value in the refined group (R=0.65, p=0.04). No significant effect of plant dyes on the acid or peroxide value of unrefined oils was observed. Conclusions: Refined and unrefined oils purchased in the city of Bialystok mostly met the standard values with the exception of cold-pressed oil from black cumin seeds, where the acid and peroxide value exceeded the values set in Codex Alimentarius.
    Źródło:
    Progress in Health Sciences; 2018, 8(2); 144-151
    2083-1617
    Pojawia się w:
    Progress in Health Sciences
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Breastfeeding as an important factor of reduced infants’ infection diseases
    Autorzy:
    Radzewicz, E.
    Milewska, M.
    Mironczuk-Chodakowska, I.
    Lendzioszek, M.
    Terlikowska, K.M.
    Powiązania:
    https://bibliotekanauki.pl/articles/1918639.pdf
    Data publikacji:
    2018
    Wydawca:
    Uniwersytet Medyczny w Białymstoku
    Tematy:
    Breastfeeding
    milk formula
    infection
    infants
    Opis:
    Purpose: Respiratory tract infections and severe allergy reactions are a leading cause of hospitalization and morbidity in infants and children. The protection of breastfeeding against infectious diseases as well as allergy development has often been suggested. The aim of the study was to assess the relationship between the various models of infant nutrition, its immunity influence and children response after 3-6 years of age. Materials and methods: The research was based on a voluntarily questionnaire, filled in by parents of pre-school children. Information on breast and milk formula feeding duration (never; 1-6 months; 6-12 months; 12-24 months; 24>months) were collected. The frequency of infections, chronic diseases, and allergies occurrence was analysed. Results: A statistically significant differences between infants breastfeeding and milk formula feeding in case of reduced infection (p=0.003) and infection recurrences (p=0.001) were found. This relationship was not found among children at further stages of development. There was no correlation between the consumption of only mothers’ milk, and the reduced occurrence of asthma, allergies, and eczema. Conclusions: Maternal milk has an influence on the reduced risk of infection in the first year of the child’s life compared to children fed only with artificial mixtures
    Źródło:
    Progress in Health Sciences; 2018, 8(2); 70-74
    2083-1617
    Pojawia się w:
    Progress in Health Sciences
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Sprouts as potential sources of dietary antioxidants in human nutrition
    Autorzy:
    Zujko, M.E.
    Terlikowska, K.M.
    Zujko, K.
    Paruk, A.
    Witkowska, A.M.
    Powiązania:
    https://bibliotekanauki.pl/articles/1918350.pdf
    Data publikacji:
    2016
    Wydawca:
    Uniwersytet Medyczny w Białymstoku
    Tematy:
    Antioxidant potential
    polyphenol
    flavonoid
    sprouts
    Opis:
    Purpose: The present study evaluates antioxidant activity, as well as polyphenol and flavonoid contents in common sprouts, available on the Polish market. The aim of this study was to extend our already published food databases. Materials and methods: Ten seed species from four plant families were analysed. Total polyphenol content of sprout extracts was determined using the Folin-Ciocalteau method. Total flavonoid content was assessed by the aluminium chloride colorimetric method. Total antioxidant status was measured using FRAP and ABTS methods. Results: The FRAP antioxidant potential was 0.60- 2.53 mmol TE (trolox equivalents)/100 g FM (fresh mass), and arranged in descending order it was: white mustard>cress>radish>broccoli>chickpea> sunflower>mung bean>wheat>green lentil>alfalfa), while the ABTS potential was 3.92-16.19 mmol TE/100 g FM (according to decreasing value: white mustard>green lentil>chickpea>sunflower>mung bean>cress> alfalfa>wheat> broccoli> radish). The polyphenol content was 160-774 mg GAE (gallic acid equivalents)/100 g FM, and flavonoid content 15-53 mg QE (quercetin equivalents)/100 g FM. Conclusion: Our results suggest that sprouts in comparison to other foods, despite small weight can be powerful sources of antioxidants. Special attention in human nutrition should be paid to white mustard sprouts as they are excellent source of polyphenol and flavonoid and are characterized by tremendous antioxidant activity.
    Źródło:
    Progress in Health Sciences; 2016, 6(2); 77-83
    2083-1617
    Pojawia się w:
    Progress in Health Sciences
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Endometrial cancer and physical activity
    Autorzy:
    Terlikowski, R.
    Łada, Z.
    Strzyż-Skalij, M.A.
    Kryński, K.
    Osmólska, M.
    Malinowska-Gleń, M.
    Kryńska, E.E.
    Terlikowska, K.M.
    Powiązania:
    https://bibliotekanauki.pl/articles/1918589.pdf
    Data publikacji:
    2018-06-21
    Wydawca:
    Uniwersytet Medyczny w Białymstoku
    Tematy:
    Endometrial cancer
    physical activity
    Opis:
    Physical activity (PA) is an important modifiable risk factor for endometrial cancer (EC). PA has been studied using diverse measures including metabolic equivalent of task MET, duration, frequency and subjective levels, but for practical reasons most of epidemiological studies use questionnaires rather than objective measures to document PA. Moderate-intense daily PA has a protective effect and have a 20-40% reduced risk of EC. In this rewiev complex and variable behaviour, and the ability of epidemiological studies to determine the relationship between PA and EC has been discussed.
    Źródło:
    Progress in Health Sciences; 2018, 8(1); 202-206
    2083-1617
    Pojawia się w:
    Progress in Health Sciences
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Ovarian cancer and inflammation. Part 1. Pro-inflammatory cytokines
    Autorzy:
    Terlikowska, K.M.
    Strzyż-Skalij, M.A.
    Kryński, K.
    Osmólska, M.
    Łada, Z.
    Malinowska-Gleń, M.
    Kryńska, E.E.
    Terlikowski, R.
    Powiązania:
    https://bibliotekanauki.pl/articles/1918599.pdf
    Data publikacji:
    2018-06-21
    Wydawca:
    Uniwersytet Medyczny w Białymstoku
    Tematy:
    Ovarian cancer
    inflammation
    cytokines
    Opis:
    Ovarian cancer is the most threatening cause of death among gynecologic malignancies and represents the fifth leading cause of death from all cancers for women. Research reveals that ovarian cancer patients exhibit significant immune responses against the tumor. In this review of the current literature chiefly the interaction of ovarian cancer tumor cells and the immune system is discussed. There is increasingly growing evidence that pro-inflammatory cytokines are involved in intricate complex of mechanisms responsible for tumorigenesis, and delicate balance between pro- and anti-inflammatory cytokines is critical for the antitumor host immune response.
    Źródło:
    Progress in Health Sciences; 2018, 8(1); 194-201
    2083-1617
    Pojawia się w:
    Progress in Health Sciences
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
      Wyświetlanie 1-8 z 8

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