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    Wyświetlanie 1-4 z 4
    Tytuł:
    Pneumonia in patients after hematopoietic stem cell transplantation
    Autorzy:
    Styczyński, Jan
    Powiązania:
    https://bibliotekanauki.pl/articles/1062942.pdf
    Data publikacji:
    2017
    Wydawca:
    Medical Education
    Tematy:
    amphotericin B lipid complex
    chemotherapy
    hematopoietic stem cell transplantation
    invasive fungal disease
    invasive fungal infection
    pneumonia
    pulmonary aspergillosis
    Opis:
    Pneumonia is one of the most frequent cause of death after hematopoietic stem cell transplantation (HSCT). The objective of this review is to present various aspects of pneumonia in this group of patients, with focus on invasive pulmonary aspergillosis and cytomegalovirus disease, being the most frequent etiological causes of pneumonia after HSCT. The review is aimed at practical approach to diagnostic and therapeutic management of pneumonia after HSCT with special attention to: definitions of infections and level of diagnosis of upper and lower respiratory tract infections, including issues specific for invasive fungal disease, pneumocystosis, cytomegalovirus disease, community acquired respiratory viral infections and bacterial pneumonia. Another topics analyzed in the review are: epidemiology and risk factors for development of infection and risk of death due to pneumonia; invasive and non-invasive diagnostics, including imaging and laboratory biomarkers; methods of pharmacological and environmental prophylaxis and specific targeted therapy of pneumonia after HSCT.
    Źródło:
    OncoReview; 2017, 7, 3; 126-138
    2450-6125
    Pojawia się w:
    OncoReview
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Invasive pulmonary aspergillosis in a child with acute myeloid leukaemia: pharmacotherapy and surgical management
    Autorzy:
    Styczyński, Jan
    Powiązania:
    https://bibliotekanauki.pl/articles/1064789.pdf
    Data publikacji:
    2016
    Wydawca:
    Medical Education
    Tematy:
    amphotericin B lipid form
    chemotherapy
    haematopoietic stem cell transplantation
    invasive fungal disease
    invasive fungal infection
    pulmonary aspergillosis
    Opis:
    This paper reports on diagnostic and therapeutic management of pulmonary invasive fungal disease (IFD) in a child with relapsed acute myeloid leukaemia, undergoing chemotherapy followed by haematopoietic stem cell transplantation. Surgical management with resection of the involved lung tissue was based on the location of fungal infiltrates close to large circulatory vessels. After examination of resected pulmonary tissue, a diagnosis of proven IFD was done. This case report is an example that aspergillosis is usually the cause for pulmonary IFD. Pharmacotherapy of pulmonary IFD should be based on compounds with good penetration to lung tissue: amphotericin B lipid form or voriconazole.
    Źródło:
    OncoReview; 2016, 6, 4; A169-174
    2450-6125
    Pojawia się w:
    OncoReview
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Severe vascular and neurological complications after hematopoietic stem cell transplantation with reduced intensity conditioning
    Autorzy:
    Czyżewski, Krzysztof
    Nierychlewska, Paulina
    Richert-Przygońska, Monika
    Cieściński, Jakub
    Styczyński, Jan
    Powiązania:
    https://bibliotekanauki.pl/articles/1035762.pdf
    Data publikacji:
    2019
    Wydawca:
    Medical Education
    Tematy:
    ALLO-HSCT
    PRES
    fludarabine
    neurotoxicity
    reduced intensity conditioning
    Opis:
    It is well established that the benefit of myeloablative ALLO-HSCT can be associated with a potential high risk of procedure-related toxicity. The objective of this report is the analysis of complications in a 17-year-old girl with AML previously treated for medulloblastoma and myelodysplastic syndrome. Thiotepa, fludarabine, treosulfan and thymoglobuline were used in conditioning regimen. During conditioning neurological complications have occurred. MRI and CT scan results revealed the coexistence of PRES with the left internal carotid artery thrombosis. The effect of fludarabine on endothelial cells could possibly contribute to irreversible CNS damage and death in presented case.
    Źródło:
    OncoReview; 2019, 9, 1; 27-30
    2450-6125
    Pojawia się w:
    OncoReview
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Multiple debulking surgery and triple antifungal therapy in abdominal-cardiac-pulmonary invasive aspergillosis
    Autorzy:
    Gałązka, Przemysław
    Demidowicz, Ewa
    Bartoszewicz, Natalia
    Czyżewski, Krzysztof
    Serafin, Zbigniew
    Zalas-Więcek, Patrycja
    Styczyński, Jan
    Powiązania:
    https://bibliotekanauki.pl/articles/1035812.pdf
    Data publikacji:
    2018
    Wydawca:
    Medical Education
    Tematy:
    triple antifungal therapy
    Opis:
    Children with acute leukemia are at a high risk of invasive fungal disease, which might manifest itself as clinically-resistant entity. The objective of this paper is to present an unusual clinical case of 17-year-old patient treated for acute lymphoblastic leukemia, with early development of disseminated invasive aspergillosis, involving the abdominal, pulmonary and cardiac structures. The patient was subjected to a combined targeted double, and later triple, antifungal therapy together with several debulking surgical interventions. The clinical course indicated a highly clinically-resistant invasive fungal disease, and the treatment was unsuccessful in this case. Limited current experience in triple antifungal therapy, abdominal aspergillosis, Aspergillus endocarditis, and possible causes of failure of antifungal therapy are discussed in the paper.
    Źródło:
    OncoReview; 2018, 8, 2; 33-37
    2450-6125
    Pojawia się w:
    OncoReview
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
      Wyświetlanie 1-4 z 4

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