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    Wyświetlanie 1-11 z 11
    Tytuł:
    Preliminary assessment of the anti-inflammatory and analgesic effects of methanol leaf extract of Cussonia barteri (Araliaceae) in rodents
    Autorzy:
    Igbe, Ighodaro
    Edosuyi, Osaze
    Okhuarobo, Agbonlahor
    Pongri, Adarki
    Maduako, Nkechi
    Ehimen, Isaac
    Powiązania:
    https://bibliotekanauki.pl/articles/2048743.pdf
    Data publikacji:
    2019
    Wydawca:
    Instytut Włókien Naturalnych i Roślin Zielarskich
    Tematy:
    Cussonia barteri
    methanol leaf extract
    anti-inflammatory activity
    analgesic activity
    metanolowy wyciąg z liści
    działanie przeciwzapalne
    działanie przeciwbólowe
    Opis:
    Introduction: Potato (Solanum tuberosum L.) is an important vegetable crop in Syria. Potato tuber moth Cussonia barteri is a small tree that grows in the sub-Saharan part of Africa. Various parts of the plant are used for the treatment of a variety of ailments in ethno-medicine. Objective: To evaluate the anti-inflammatory and analgesic effect of the methanol leaf extract of Cussonia barteri. Material and methods: The leaves were air-dried, powdered and repeatedly extracted with methanol using a Soxhlet apparatus. The resulting methanol extract (100, 200 and 400 mg/kg) was evaluated for antiinflammatory activity using carrageenan-induced paw oedema, xylene-induced ear oedema and formalininduced arthritis tests. Analgesic effect was evaluated using acetic acid-induced mouse writhing, hot plate and tail flick tests. Results: All doses of the extract significantly (p<0.05) reduced carrageenan-induced paw oedema, however the 400 mg/kg dose gave a sustained effect. The extract significantly inhibited xylene induced ear oedema at all doses. There were no significant (p>0.05) reductions in paw swellings due to formalin. In the acetic acid induced writhing test, the extract significantly (p<0.05) decreased writhing at 400 mg/kg only. Reaction times were not significantly different from the control in the hot plate and tail flick tests. Conclusion: This study has shown that the methanol extract possesses acute anti-inflammatory and peripherally mediated analgesic effects.
    Źródło:
    Herba Polonica; 2019, 65, 3; 22-31
    0018-0599
    Pojawia się w:
    Herba Polonica
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Antibacterial and antifungal effects of acetone extracts from fifty spice and herb plants
    Autorzy:
    Demirkol, Gurkan
    Erturk, Omer
    Powiązania:
    https://bibliotekanauki.pl/articles/2048741.pdf
    Data publikacji:
    2019
    Wydawca:
    Instytut Włókien Naturalnych i Roślin Zielarskich
    Tematy:
    antimicrobial
    antibacterial
    antifungal
    spices
    działanie przeciwdrobnoustrojowe
    przeciwbakteryjne
    przeciwgrzybicze
    przyprawy
    Opis:
    Introduction: Chemical industry is obligatory to improve new chemically effective components. Spices are potential new antimicrobials. Objective: The present study was designed to evaluate the antibacterial and antifungal activity of fifty aromatic spices and medicinal herbs obtained from Turkey. Material and methods: In vitro antibacterial activities of a total of fifty acetone extracts from aromatic spices and medicinal herbs were studied by disc diffusion and agar diffusion method. The extracts were tested against three Gram-positive bacteria (Listeria monocytogenes, Staphylococcus aureus, Bacillus cereus), four Gram-negative bacteria (Proteus vulgaris, Escherichia coli, Pseudomonas aeruginosa, Salmonella typhimurium) and two fungi (Aspergillus niger, Candida albicans). Results: The highest antimicrobial activity was observed in the extract of Alpinia officinarum against Salmonella typhimurium and Cassia angustifolia against Bacillus cereus. Many of the extracts showed minimum inhibition concentration at even lowest dose. Conclusion: The obtained results showed that aromatic spices and medicinal herbs may be used as natural antimicrobials against diseases.
    Źródło:
    Herba Polonica; 2019, 65, 3; 32-38
    0018-0599
    Pojawia się w:
    Herba Polonica
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Antiprotozoal investigation of three Combretum species (Combretaceae) growing in Nigeria
    Autorzy:
    Ogbole, O.O.
    Akinleye, T.E.
    Segun, P.A.
    Fasinu, P.S.
    Powiązania:
    https://bibliotekanauki.pl/articles/2048946.pdf
    Data publikacji:
    2019
    Wydawca:
    Instytut Włókien Naturalnych i Roślin Zielarskich
    Tematy:
    Combretum racemosum
    Combretum platypterum
    Combretum zenkeri
    infectious diseases
    antiprotozoal assay
    działanie przeciwpierwotniakowe
    choroby zakaźne
    Opis:
    Introduction: Combretum species has been utilised for decades in African indigenous medical practices for the treatment of several parasitic infections. Objectives: This study aims at investigating the antileishmanial, antiplasmodial and antitrypanosomal properties of Combretum racemosum, Combretum platypterum and Combretum zenkeri. Methods: The leaf extracts of the plants were screened against two strains of Plasmodium falciparum using Plasmodium lactate dehydrogenase (pLDH) assay; promastigote and amastigote forms of Leishmania donovani; and Trypanosoma brucei brucei using Alamar Blue assay. Cytotoxicity screening were also carried out on African green monkey kidney cell line (Vero) and human monocytic leukemia (THP-1) cell lines. Results: C. racemosum was active against chloroquine-sensitive (D6) and chloroquine-resistant (W2) strains of P. falciparum (IC50 of 25.6 and 26.7 µg/ml, respectively) and exerted significant antiprotozoal activities against T. brucei brucei (IC50 = 18.44 µg/ml). The extract of C. platypterum displayed a slightly lower antiplasmodial activity when compared to C. racemosum, while C. zenkeri was inactive against the parasites. In addition, the extracts failed to display significant inhibitory activity on the proliferation of L. donovani. Conclusions: This study supports the ethnomedicinal use of C. racemosum. Further research needs to be carried out to identify the antiprotozoal compounds in C. racemosum, as this could be explored for possible antiprotozoal drug development.
    Źródło:
    Herba Polonica; 2019, 65, 4; 37-44
    0018-0599
    Pojawia się w:
    Herba Polonica
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Composition, antioxidant and antimicrobial activities of cold-pressed and distilled essential oils of Origanum onites L. and Lavandula officinalis L. relationships evaluated by SEM microscopy
    Autorzy:
    Erturk, O.
    Aydin, G.
    Ayvaz, M.C.
    Baskan, C.
    Powiązania:
    https://bibliotekanauki.pl/articles/2049191.pdf
    Data publikacji:
    2020
    Wydawca:
    Instytut Włókien Naturalnych i Roślin Zielarskich
    Tematy:
    Origanum onites
    Lavandula angustifolia
    essential oil
    antioxidant activity
    antimicrobial activity
    morphological change
    scanning electron microscopy
    chemical component
    gas chromatography-mass spectrometry
    oregano
    lawenda
    olejek eteryczny
    działanie antyoksydacyjne
    analiza GC-MS
    działanie przeciwdrobnoustrojowe
    Opis:
    Introduction: In order to prevent increased bacterial resistance, it is important to use herbal medicines with less side effects. Objective: In this study, the chemical composition, antimicrobial, antioxidant activities and SEM images of Lavandula officinalis and Origanum onites oils obtained in two different ways were determined. Methods: The antimicrobial activity of the oils was determined against reference and multiple strains of foodborne and pathogenic bacteria. The each essential oil sample were analyzed by GC–MS. Antioxidant activities of the samples were examined through DPPH• and ABTS•+ radical scavenging and FRAP assays. Results: The results indicate that the oils of obtained from Origanum onites and Lavandula officinalis exhibited relatively strong antibacterial and antifungal activity. In addition, the antioxidant activities detected were remarkable. Morphological changes in bacterial cells treated with essential oil samples were demonstrated with SEM images. In addition, the chemical components of the oil samples obtained by both water steam and cold press were revealed by GC-MS analysis and compared. Conclusion: When all the obtained results are evaluated together; these plants could be suitable for using as antimicrobial and antioxidative agents in several industries such as food, cosmetic, etc.
    Źródło:
    Herba Polonica; 2020, 66, 4; 43-54
    0018-0599
    Pojawia się w:
    Herba Polonica
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Production stages, microbiological risk and benefits on health of herbal teas
    Autorzy:
    Akduman, G.
    Korkmaz, I.O.
    Powiązania:
    https://bibliotekanauki.pl/articles/2049211.pdf
    Data publikacji:
    2020
    Wydawca:
    Instytut Włókien Naturalnych i Roślin Zielarskich
    Tematy:
    herbal tea
    production stage
    health
    contamination
    antioxidant activity
    microbiological risk
    benefit
    herbata ziołowa
    zdrowie
    zanieczyszczenie
    działanie antyoksydacyjne
    Opis:
    Plants have been used to prepare herbal infusions for centuries. Production of herbal tea consists of several steps, beginning with harvesting, cleaning form residues, drying, storage of herb in a suitable material, grinding, and blending. Te plants grow in different regions and climatic conditions, varying by their physical properties. They are consumed for different purposes and due to their chemical constituents. Many of them have therapeutic effects. Besides their various benefits and even antimicrobial effects, they also carry some microorganisms. Thus, the botanical characteristics and effects on the health of frequently consumed herbal teas and recommendations on their consumption with considered microbial risks are reviewed in this article.
    Źródło:
    Herba Polonica; 2020, 66, 4; 68-78
    0018-0599
    Pojawia się w:
    Herba Polonica
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    In silico studies of selected xanthophylls as potential candidates against SARS-CoV-2 targeting main protease (Mpro) and papain-like protease (PLpro)
    Autorzy:
    Karpiński, T.M.
    Kwaśniewski, M.
    Ożarowski, M.
    Alam, R.
    Powiązania:
    https://bibliotekanauki.pl/articles/2049355.pdf
    Data publikacji:
    2021
    Wydawca:
    Instytut Włókien Naturalnych i Roślin Zielarskich
    Tematy:
    protease
    papain-like protease
    xanthophyll
    coronavirus
    COVID-19
    antiviral activity
    koronawirus
    pandemia
    działanie przeciwwirusowe
    projektowanie leków wspomagane komputerowo
    Opis:
    Introduction: The main protease (Mpro) and the papain-like protease (PLpro) are essential for the replication of SARS-CoV-2. Both proteases can be targets for drugs acting against SARS-CoV-2. Objective: This paper aims to investigate the in silico activity of nine xanthophylls as inhibitors of Mpro and PLpro. Methods: The structures of Mpro (PDB-ID: 6LU7) and PLpro (PDB-ID: 6W9C) were obtained from RCSB Protein Data Bank and developed with BIOVIA Discovery Studio. Active sites of proteins were performed using CASTp. For docking the PyRx was used. Pharmacokinetic parameters of ADMET were evaluated using SwissADME and pkCSM. Results: β-cryptoxanthin exhibited the highest binding energy: –7.4 kcal/mol in the active site of Mpro. In PLpro active site, the highest binding energy had canthaxanthin of –9.4 kcal/mol, astaxanthin –9.3 kcal/mol, flavoxanthin –9.2 kcal/mol and violaxanthin –9.2 kcal/mol. ADMET studies presented lower toxicity of xanthophylls in comparison to ritonavir and ivermectin. Conclusion: Our findings suggest that xanthophylls can be used as potential inhibitors against SARS-CoV-2 main protease and papain-like protease.
    Źródło:
    Herba Polonica; 2021, 67, 2; 1-8
    0018-0599
    Pojawia się w:
    Herba Polonica
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Phytochemistry and biological activities of Opuntia seed oils: Opuntia dillenii (Ker Gawl.) Haw. and Opuntia ficus-indica (L.) Mill. A review
    Autorzy:
    Bouhrim, M.
    Bouknana, S.
    Ouassou, H.
    Boutahiri, S.
    Daoudi, N.E.
    Bnouham, M.
    Powiązania:
    https://bibliotekanauki.pl/articles/2049338.pdf
    Data publikacji:
    2021
    Wydawca:
    Instytut Włókien Naturalnych i Roślin Zielarskich
    Tematy:
    Opuntia
    Opuntia dillenii
    Opuntia ficus-indica
    seed oil
    phytochemistry
    biological activity
    olej z nasion
    fitochemia
    działanie biologiczne
    Opis:
    Opuntia species belong to semi-arid and arid regions of Mexico and the United States. O. ficus-indica and O. dillenii are commonly used in alternative medicine to treat various diseases. Up to date, several scientific works have been carried out on the different parts of these plants. However, over the last few years, studies have been focusing on the oil obtained from the fruit seeds of these species. For this reason, this study aims to draw the attention of researchers toward the phytochemical and the pharmacological effects of these two Opuntia oils, which would help set up other scientific projects that promote these products. Phytochemical studies have shown that these oils are rich in biologically active molecules, such as unsaturated fatty acids and phytosterols (mainly linoleic acid and β-sitosterol), as well as vitamin E, which is represented only by the γ-tocopherol. Besides, these oils are rich in polyphenols that protect them from photo-oxidation. Moreover, several studies have shown their antioxidant, anti-diabetic, antibacterial, antifungal, anti-inflammatory,hepatoprotective, and gastroprotective activities, as well as their hypolipidemic properties. The beneficial effects of these oils include also their ability to block the weight loss, and what makes them more interesting is their safety, according to the literature.
    Źródło:
    Herba Polonica; 2021, 67, 2; 49-64
    0018-0599
    Pojawia się w:
    Herba Polonica
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Isolation, characterization and evaluation of anti-proliferative properties of andrographolide isolated from Andrographis paniculata on cultured HaCaT cells
    Autorzy:
    Jindal, S.
    Awasthi, R.
    Singare, D.
    Kulkarni, G.T.
    Powiązania:
    https://bibliotekanauki.pl/articles/2049322.pdf
    Data publikacji:
    2021
    Wydawca:
    Instytut Włókien Naturalnych i Roślin Zielarskich
    Tematy:
    Andrographis paniculata
    andrographolide
    psoriasis
    inflammatory skin disease
    proliferation
    keratinocyte
    epidermis
    andrografolid
    brodziuszka wiechowata
    łuszczyca
    keratynocyty naskórka
    działanie antyproliferacyjne
    Opis:
    Introduction: Psoriasis is an inflammatory skin disease characterized by hyper-proliferation, abnormal epidermal keratinocytes and inflammatory infiltration. It affects approximately 4% of the population globally. Herbal extracts have better results with less toxic effects than the synthetic drugs in the treatment of psoriasis. Objective: Present study was aimed to access the anti-psoriatic effect of andrographolide extracted from Andrographis paniculate (A. paniculata). Method: We extracted, characterized, and screened the extracted andrographolide for anti-proliferative characteristics using cultured cell model of human HaCaT keratinocyte. Results: Andrographolide at 31.25 µg/mL (90 µM) demonstrated significant inhibitory effect on human HaCaT keratinocytes proliferation in cell culture. To our best knowledge, we reported the anti-proliferative potency of andrographolide extracted from A. paniculata for the first time. Conclusion: The results suggest that the andrographolide extracted from A. paniculata plant may have potential to be used in the management of psoriasis.
    Źródło:
    Herba Polonica; 2021, 67, 1; 35-45
    0018-0599
    Pojawia się w:
    Herba Polonica
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Anti-HIV activity of some natural phenolics
    Autorzy:
    El-Ansari, M.A.
    Ibrahim, L.F.
    Sharaf, M.
    Powiązania:
    https://bibliotekanauki.pl/articles/2049059.pdf
    Data publikacji:
    2020
    Wydawca:
    Instytut Włókien Naturalnych i Roślin Zielarskich
    Tematy:
    medicinal plants
    phenolics
    AIDS
    anti-HIV activity
    mechanism of action
    rośliny lecznicze
    związki fenolowe
    działanie anty-HIV
    mechanizm działania
    Opis:
    Acquired immunodeficiency syndrome (AIDS) is an immunosuppressive disease caused by human immunodeficiency virus (HIV). The urgent need for searching novel anti-HIV/AIDS medicines is a global concern. So far, a lot of medicinal and aromatic plants (MAPs) have been analyzed to select those that could assist in the prevention and/or amelioration of the disease. Among biologically active compounds present in these plants, one of the most promising group are phenolics. The purpose of this article was to report antiHIV activity of selected phenolic compounds of plant origin.
    Źródło:
    Herba Polonica; 2020, 66, 2; 34-43
    0018-0599
    Pojawia się w:
    Herba Polonica
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Antioxidant and anti-candida activity of selected medicinal plants of Indian origin
    Autorzy:
    Prajapati, S.
    Bhardwaj, A.
    Gupta, P.
    Powiązania:
    https://bibliotekanauki.pl/articles/2049066.pdf
    Data publikacji:
    2020
    Wydawca:
    Instytut Włókien Naturalnych i Roślin Zielarskich
    Tematy:
    fungal disease
    antioxidant
    medicinal plant
    antifungal activity
    Candida albicans
    plant extract
    Terminalia chebula
    Thuja occidentalis
    Syzygium jambolanum
    przeciwutleniacze
    medycyna tradycyjna
    działanie przeciwgrzybicze
    wyciąg roślinny
    rośliny lecznicze
    Opis:
    Introduction: Fungal disseases are the most common opportunistic infection. Objective: The main aims of the study were to determine phenolic content and to evaluate the antioxidant and anti-candida activity of the selected Indian-origin plant extracts from the fruit pulp, stem, leaves, and seeds of three plants of Indian origin. Material and methods: The extracts from Terminalia chebula, Thuja occidentalic and Syzygium jambolanum were investigated. The total phenolic content, antioxidant potential of different crude extracts was accessed using the free radical, 1,1-diphenyl-2-picrylhydrazyl (DPPH) and 2,2’-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS). Anti-candida activity was evaluated using disk diffusion method and broth dilution assay against Candida albicans. Results: Ethanol and methanol extracts of Indian traditional plants possessed high radical scavenging activity: T. chebula 29.38±0.15, T. occidentalis 6.26±0.24 and S. jambolanum 25.64±0.18 at 0.32 mg/ml. The extracts exhibited good zones of inhibition diameters ranged between: for T. chebula 6.33±0.57 mm and 19.66±1.52 mm in diameter, S. jambolanum 7.00±00 mm and 23.33±1.52 and T. occidentalis 7.66±0.57 and 17.00±1.00 mm. C. albicans were susceptible to all three tested extract at different concentrations. The lowest MIC 1.95 mg/ml was recorded with S. jambolanum while the T. chebula and T. occidentalis inhibited the growth at 3.90 mg/ml, respectively, against the C. albicans. Conclusion: The study result paves an overall view on the bioactivities of three traditional Indian medicinal plants crude extracts.
    Źródło:
    Herba Polonica; 2020, 66, 3; 1-12
    0018-0599
    Pojawia się w:
    Herba Polonica
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Effect of different drying processes on an antioxidant potential of three species of the Lamiaceae family
    Autorzy:
    Kwaśniewska-Karolak, I.
    Mostowski, R.
    Powiązania:
    https://bibliotekanauki.pl/articles/2049315.pdf
    Data publikacji:
    2021
    Wydawca:
    Instytut Włókien Naturalnych i Roślin Zielarskich
    Tematy:
    drying process
    herb
    thyme
    Thymus vulgaris
    sage
    Salvia officinalis
    rosemary
    Rosmarinus officinalis
    antioxidant potential
    Lamiaceae
    spice plant
    ascorbic acid
    suszenie
    zioła
    działanie antyoksydacyjne
    kwas askorbinowy
    chlorofil
    Opis:
    Introduction: Spice plants are a rich source of biologically active compounds. Processes of drying, limits the development of microorganisms and biochemical reactions in raw herbs, at the same time modifies their chemical composition. Objective: The aim of this work was to evaluate the effect of drying process of selected plants on their antioxidant potential and the content of biologically active compounds. Methods: The herbal materials thyme herb (Thymus vulgaris L.), sage leaves (Salvia officinalis L.) and rosemary leaves (Rosmarinus officinalis) were dried using two methods: convective (at 30° C), and freeze-drying. In both, fresh and subjected to drying processes herbs, changes in total polyphenol and antioxidant potential (with the DPPH radical), vitamin C (in the form of ascorbic acid) and chlorophyll pigments contents, were studied. Results: The highest content of polyphenols and vitamin C was recorded in rosemary, while sage was characterized by the highest content of chlorophylls. It was found that the drying processes caused large losses of vitamin C (ascorbic acid) and dyes in comparison to the fresh material. The highest losses of vitamin C occurred in convection dried sage (95%), while most was preserved in lyophilised thyme (losses 74%). Drying had also influenced the reduction of the content of chlorophylls with the largest loss of these compounds, at 94% observed in the freeze-dried rosemary. However, the content of polyphenols increased, underscoring a large impact on the antioxidant activity of herbs. Conclusions: Drying processes resulted in the release of phenolic compounds, so their content increased three to four times in the case of rosemary and sage. The largest increase was observed in the case of lyophilised thyme. Simultaneously, the antioxidant potential was significantly increased. Herbal droughts proved to be a rich source of antioxidant compounds with promising applications as a food additive.
    Źródło:
    Herba Polonica; 2021, 67, 1; 8-17
    0018-0599
    Pojawia się w:
    Herba Polonica
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
      Wyświetlanie 1-11 z 11

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