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Tytuł:
Beta-actin in human colon adenocarcinoma cell lines with different metastatic potential.
Autorzy:
Nowak, Dorota
Skwarek-Maruszewska, Aneta
Zemanek-Zboch, Magdalena
Malicka-Błaszkiewicz, Maria
Powiązania:
https://bibliotekanauki.pl/articles/1041430.pdf
Data publikacji:
2005
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
actin cytoskeleton
β-actin
colon adenocarcinoma
invasiveness
Opis:
Human colon adenocarcinoma LS180 parental cell line and selected variants, characterized by different metastatic capacity were used to examine, whether a correlation exists between β-actin expression, its subcellular distribution and metastatic potential of these cells. Cytosolic fraction (supernatant 105000 × g), isolated from the tumor cells was used as a source for actin quantification. The higher level of β-actin was observed in the cytosol of three selected sublines to compare with LS180 parental line. Statistically significant increase of β-actin level in highly motile EB3 cells variant should be underlined to compare with the other sublines. Distinct differences in the phenotype of adenocarcinoma cell variants were found, such as the changes in cells shape, cells spreading and ability to attach to the surface of culture dish. Actin cytoskeleton was visualized with fluorescence microscopy application and microfilaments rhodamine-conjugated phalloidin staining. β-actin subcellular localization was done by immunofluorescence staining with monoclonal anti-β actin antibodies. In the elongated cells (LS180, 3LNLN), this isoactin is dispersed in the whole cell body and concentrates in pseudopods and at the leading edges, when in the rounded variant (EB3) β-actin dominates mainly in cortical ring under cellular membrane and it is also seen in the subtle protrusions. Summary of our former (Nowak et al., 2002, Acta Biochim. Polon., 49: 823) and current data lead to the conclusion that there is a distinct correlation between metastatic capacity of examined human colon adenocarcinoma cells, the state of actin polymerization, actin cytoskeleton organization and β-actin expression.
Źródło:
Acta Biochimica Polonica; 2005, 52, 2; 461-468
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Actin in human colon adenocarcinoma cells with different metastatic potential.
Autorzy:
Nowak, Dorota
Krawczenko, Agnieszka
Duś, Danuta
Malicka-Błaszkiewicz, Maria
Powiązania:
https://bibliotekanauki.pl/articles/1043684.pdf
Data publikacji:
2002
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
state of actin polymerization
colon adenocarcinoma cell lines
actin
Opis:
Four human colon adenocarcinoma cell line variants with different metastatic potential were used to examine whether a correlation exists between actin level, state of actin polymerization and invasiveness of tumour cells. Monomeric (G), total (T) and filamentous (F) actin were determined in the cytosolic fraction of these cells. A statistically significant decrease in G actin level and increase in the state of actin polymerization (measured by F:G actin ratio) were found in the cytosol of three cell variants with higher metastatic potential and invasiveness (EB3, 3LNLN, 5W) compared with the parental cell line (LS180). Our experimental data lead to the conclusion that there is a correlation between the metastatic capacity of human colon adenocarcinoma cells and the state of actin polymerization.
Źródło:
Acta Biochimica Polonica; 2002, 49, 4; 823-828
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Identification of actin from hepatoma Morris 5123 cells
Autorzy:
Nowak, Dorota
Kochman, Agata
Malicka-Błaszkiewicz, Maria
Powiązania:
https://bibliotekanauki.pl/articles/1044454.pdf
Data publikacji:
1999
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
actin isoforms
affinity chromatography
hepatoma Morris 5123
actin
Opis:
The hepatoma Morris 5123 tumor growth is accompanied by changes in actin content and polymerization (Malicka-Błaszkiewicz et al. (1995) Mat. Med. Pol., 27, 115-118;  Nowak et al. (1995) J. Exp. Cancer Res. 14, 37-40). Presently actin isoforms from cytosol and  cytoskeleton fractions were separated by SDS/PAGE and identified with antibodies directed against different actin isoforms. Actin isolated from the cytosol by affinity chromatography on DNase I bound to agarose shows the presence of only one protein spot on 2D gel electrophoresis corresponding to the mobility of the rabbit α skeletal muscle actin (M^r 43000) and isoelectric point equal to 5.3. It interacts only with monoclonal anti β actin isoform antibodies, posing the question of differential affinity of actin isoforms to DNase I.
Źródło:
Acta Biochimica Polonica; 1999, 46, 4; 949-959
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Gelsolin in human colon adenocarcinoma cells with different metastatic potential
Autorzy:
Litwin, Monika
Mazur, Antonina
Nowak, Dorota
Mannherz, Hans
Malicka-Błaszkiewicz, Maria
Powiązania:
https://bibliotekanauki.pl/articles/1040503.pdf
Data publikacji:
2009
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
gelsolin
actin
cancer
Opis:
Gelsolin, one of a major actin-binding proteins, is involved in the regulation of actin cytoskeleton organization by its severing and capping activity towards actin filaments. Human colon adenocarcinoma cell line LS180 and its selected variants of different metastatic potential were used to check for a correlation between gelsolin level, its subcellular localization and the invasive capacity of cells. Based on immunoblotting experiments, a decreased level of gelsolin was detected in the most invasive 5W subline when compared to the parental cell line LS180. The intracellular distribution of actin filaments and gelsolin in colon adenocarcinoma cells was examined by confocal microscopy. In the 5W subline, unlike in the other examined cells, gelsolin was colocalized with filamentous actin at the cell periphery. In summary, in human colon adenocarcinoma cells, gelsolin level and its subcellular distribution seem to correlate with their metastatic potential.
Źródło:
Acta Biochimica Polonica; 2009, 56, 4; 739-743
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Stabilization of actin filaments with phalloidin has no influence on chloroplast movement in Arabidopsis mesophyll cells
Autorzy:
Krzeszowiec, W.
Jagiello-Flasinska, D.
Gabrys, H.
Powiązania:
https://bibliotekanauki.pl/articles/79834.pdf
Data publikacji:
2013
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
conference
actin cytoskeleton
chloroplast
angiosperm
Arabidopsis thaliana
mesophyll cell
actin filament
phalloidin
Źródło:
BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology; 2013, 94, 3
0860-7796
Pojawia się w:
BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
A new method to precipitate myosin v from rat brain soluble fraction
Autorzy:
Melo, Hugo
Coelho, Milton
Powiązania:
https://bibliotekanauki.pl/articles/1041042.pdf
Data publikacji:
2007
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
myosin V
ATPase
F-actin
Opis:
Myosin can be precipitated from soluble fraction under different assay conditions. This paper describes a new method for precipitating myosin V from rat brain soluble fraction. Brains were homogenized in 50 mM imidazole/HCl buffer, pH 8.0, containing 10 mM EDTA/EGTA, 250 mM sucrose, 1 mM DTT and 1 mM benzamidine, centrifuged at 45000 × g for 40 min and the supernatant was frozen at -20 °C. Forty-eight hours later, the supernatant was thawed, centrifuged at 45000 × g for 40 min and the precipitate was washed in 20 mM imidazole buffer pH 8.0. SDS/PAGE analysis showed four polypeptides in the precipitate: 205, 150, 57 and 43 kDa. The precipitate presented high Mg2+-ATPase activity, which co-purifies with p205. This polypeptide was recognized by a specific myosin V antibody and was proteolised by calpain, generating two stable polypeptides: p130 and p90. The Mg2+-ATPase activity was not stimulated by calcium in both the absence and presence of exogenous calmodulin and the K+/EDTA-ATPase activity represented 25% of the Mg2+-ATPase activity. In this work, myosin V from rat brain was precipitated by freezing the soluble fraction and was co-purificated with a 45 kDa polypeptide.
Źródło:
Acta Biochimica Polonica; 2007, 54, 3; 575-581
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
The effect of methotrexate on actin and invasiveness of hepatoma Morris 5123 cells in culture.
Autorzy:
Otrocka, Magdalena
Verschueren, Hendrik
Malicka-Błaszkiewicz, Maria
Powiązania:
https://bibliotekanauki.pl/articles/1044048.pdf
Data publikacji:
2001
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
hepatoma Morris 5123
invasiveness
methotrexate
actin
Opis:
Monomeric (G), total (T) and filamentous (F) actin and the state of actin polymerisation (F:G) were determined and actin filaments were visualized in hepatoma Morris 5123 cells cultured in the presence of methotrexate (MTX) at various concentration. The exposure of the cells to this drug resulted in a decrease of total and polymerised actin in cytoplasm and in some changes in actin filament organization. This coincided with a decrease of the cells' ability to migrate through Matrigel coated filters and with inhibition of tumour formation after reimplantation of the methotrexate treated cells to experimental rats.
Źródło:
Acta Biochimica Polonica; 2001, 48, 4; 1051-1060
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Ovocystatin affects actin cytoskeleton organization and induces proapoptotic activity
Autorzy:
Malicka-Blaszkiewicz, Maria
Filipczak, Nina
Gołąb, Krzysztof
Juszczyńska, Katarzyna
Sebzda, Tadeusz
Gburek, Jakub
Powiązania:
https://bibliotekanauki.pl/articles/1039207.pdf
Data publikacji:
2014
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
ovocystatin
egg white cystatin
actin cytoskeleton
apoptosis
Opis:
Ovocystatin is a chicken egg white protein, generally known for its inhibitory activity against cysteine proteases. However, biological activity of ovocystatin does not seem to be well recognized in respect to other possible cellular effects. Our attention has been focused on ovocystatin cytotoxic effects in relation to its influence on actin cytoskeleton organization and apoptosis induction. In vitro studies with human melanoma A375, human cervix HeLa cancer cells and normal human fibroblasts - NHDF were done. Cytotoxic activity of ovocystatin was seen in respect to apoptosis induction - manifested by cell shape changes, phosphatydylserine translocation and actin cytoskeleton reorganization. Normal human fibroblasts have shown lower sensitivity to ovocystatin as compared with human melanoma A375 and human cervix HeLa cancer cells. In conclusion, ovocystatin affects actin cytoskeleton organization and displays proapoptotic activity towards applied cell lines. This implicates its application as a potential anticancer drug. However, its adverse effects on normal cells should be taken into consideration.
Źródło:
Acta Biochimica Polonica; 2014, 61, 4; 753-758
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Modyfikacje potranslacyjne aktyny
Posttranslational modifications of actin
Autorzy:
Rędowicz, Maria
Powiązania:
https://bibliotekanauki.pl/articles/1033933.pdf
Data publikacji:
2018
Wydawca:
Polskie Towarzystwo Przyrodników im. Kopernika
Tematy:
actin
cytoskeleton
filament
regulation
aktyna
cytoszkielet
regulacja
Opis:
Aktyna, komponent cytoszkieletu komórek eukariotycznych, to jedno z białek najistotniejszych dla funkcjonowania organizmów i najlepiej zachowanych w toku ewolucji. Ta globularna cząsteczka o masie cząsteczkowej około 42,3 kDa występuje zarówno w formie monomerycznej, jak i spolimeryzowanej (filamenty), a zdolność do dynamicznej reorganizacji aktyny jest niezbędna dla życia komórki. Przejście pomiędzy obiema formami jest możliwe dzięki precyzyjnej w czasie i przestrzeni, dynamicznej regulacji organizacji aktyny przez szereg białek wiążących się zarówno z monomerami, jak i filamentami aktyny. Istotnym czynnikiem wpływającym na stopień spolimeryzowania aktyny są także liczne modyfikacje potranslacyjne tego białka. Niniejszy artykuł przeglądowy jest poświęcony omówieniu tego obszernego i wciąż mało poznanego zagadnienia, a w szczególności opisowi jakim modyfikacjom ulega aktyna i w jaki sposób modyfikacje te wpływają na strukturę i funkcje tego wyjątkowego białka.
Actin, a constituent of the cytoskeleton of eukaryotic cells, is one of the most important as well as best evolutionary conserved proteins. This globular protein with molecular mass of ~42.3 kDa exists in the cell both in the monomeric and filamentous form, and ability to undergo dynamic reorganization of these two forms is absolutely crucial for cell survival. The monomer-filament transition, precisely controlled in time and space, is possible due to interaction of actin with a panoply of proteins binding to either monomeric or filamentous actin. Yet another factor is affecting actin organization, namely numerous posttranslational modifications. This review article is devoted to presentation of this broad and still unrecognized topic with emphasis on description of the type of actin modifications and how they affect actin structure and function.
Źródło:
Kosmos; 2018, 67, 1; 43-55
0023-4249
Pojawia się w:
Kosmos
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Is MLC phosphorylation essential for the recovery from ROCK inhibition in glioma C6 cells?
Autorzy:
Korczyński, Jarosław
Sobierajska, Katarzyna
Krzemiński, Patryk
Wasik, Anna
Wypych, Dorota
Pomorski, Paweł
Kłopocka, Wanda
Powiązania:
https://bibliotekanauki.pl/articles/1039964.pdf
Data publikacji:
2011
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
RhoA
myosin II
calcium signaling
actin
MLC phosphorylation
Opis:
Inhibition of Rho-associated protein kinase (ROCK) activity in glioma C6 cells induces changes in actin cytoskeleton organization and cell morphology similar to those observed in other types of cells with inhibited RhoA/ROCK signaling pathway. We show that phosphorylation of myosin light chains (MLC) induced by P2Y2 receptor stimulation in cells with blocked ROCK correlates in time with actin cytoskeleton reorganization, F-actin redistribution and stress fibers assembly followed by recovery of normal cell morphology. Presented results indicate that myosin light-chain kinase (MLCK) is responsible for the observed phosphorylation of MLC. We also found that the changes induced by P2Y2 stimulation in actin cytoskeleton dynamics and morphology of cells with inhibited ROCK, but not in the level of phosphorylated MLC, depend on the presence of calcium in the cell environment.
Źródło:
Acta Biochimica Polonica; 2011, 58, 1; 125-130
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Influence of BCR/ABL fusion proteins on the course of Ph leukemias.
Autorzy:
Telegeev, Gennady
Dubrovska, Anna
Dybkov, Mykhaylo
Maliuta, Stanislav
Powiązania:
https://bibliotekanauki.pl/articles/1041568.pdf
Data publikacji:
2004
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
Philadelphia chromosome
actin cytoskeleton
leukemia
BCR/ABL gene
Opis:
The hallmark of chronic myeloid leukemia (CML) and a subset of acute lymphoblastic leukemia (ALL) is the presence of the Philadelphia chromosome as a result of the t(9;22) translocation. This gene rearrangement results in the production of a novel oncoprotein, BCR/ABL, a constitutively active tyrosine kinase. There is compelling evidence that the malignant transformation by BCR/ABL is critically dependent on its Abl tyrosine kinase activity. Also the bcr part of the hybrid gene takes part in realization of the malignant phenotype. We supposed that additional mutations accumulate in this region of the BCR/ABL oncogene during the development of the malignant blast crisis in CML patients. In ALL patients having p210 fusion protein the mutations were supposed to be preexisting. Sequencing of PCR product of the BCR/ABL gene (Dbl, PH region) showed that along with single-nucleotide substitutions other mutations, mostly deletions, had occurred. In an ALL patient a deletion of the 5th exon was detected. The size of the deletions varied from 36 to 220 amino acids. For one case of blast crisis of CML changes in the character of actin organization were observed. Taking into account the functional role of these domains in the cell an etiological role of such mutations on the disease phenotype and leukemia progression is plausible.
Źródło:
Acta Biochimica Polonica; 2004, 51, 3; 845-849
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Insight into the kinetics and the mode of the interaction between smooth muscle calponin and F-actin.
Autorzy:
Kołakowski, Janusz
Dąbrowska, Renata
Powiązania:
https://bibliotekanauki.pl/articles/1043785.pdf
Data publikacji:
2002
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
light scattering
fluorescence
actin-binding
calponin
stopped-flow
Opis:
Kinetics of the smooth muscle calponin-F-actin interaction was studied by stopped- flow measurements of light scattering and fluorescence intensity of pyrene-labelled F-actin. The intensity and character of the changes in light scattering, and thus the mode of calponin binding to actin filaments leading to changes in their shape and bundling, depend on the molar ratio of the two proteins. Parallel measurements of pyrene-fluorescence quenching upon calponin binding revealed that intrinsic conformational changes in actin filaments are delayed relative to the binding process and are not markedly influenced by the mode of calponin binding. Bundling of actin filaments by calponin was not correlated with fluorescence changes and thus with alterations in the structure of actin filaments.
Źródło:
Acta Biochimica Polonica; 2002, 49, 2; 471-479
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Filamenty cienkie i mikrofilamenty - funkcjonalne kompleksy aktyny z tropomiozyną
Thin filaments and microfilaments - functional complexes of actin and tropomyosin
Autorzy:
Moraczewska, Joanna
Powiązania:
https://bibliotekanauki.pl/articles/1033932.pdf
Data publikacji:
2018
Wydawca:
Polskie Towarzystwo Przyrodników im. Kopernika
Tematy:
actin
dynamics
filament
regulation
tropomyosin
aktyna
dynamika
regulacja
tropomiozyna
Opis:
Aktyna jest uniwersalnym białkiem o strukturze dobrze zachowanej w toku ewolucji. W komórkach aktyna istnieje w równowadze pomiędzy formą monomeryczną i filamentową. Pomimo zachowanej w toku ewolucji struktury, aktyna pełni zdumiewająco wiele różnorodnych funkcji. Jest to możliwe dzięki zdolności aktyny do oddziaływania z wieloma białkami, wśród których znajdują się motory miozynowe oraz białka regulujące dynamiczną polimeryzację i depolimeryzację aktyny. Nadrzędnymi regulatorami filamentów aktynowych są tropomiozyny, rodzina superhelikalnych białek, które polimeryzują wzdłuż filamentowej aktyny, dzięki czemu stabilizują filamenty zapobiegając ich depolimeryzacji oraz kontrolują dostęp i aktywność białek wiążących aktynę. Tropomiozyny działają jako "stróże" filamentu, którzy kontrolują oddziaływania aktyny, co prowadzi do segregacji białek wiążących aktynę do swoistych przedziałów komórkowych gdzie białka te realizują określone funkcje komórkowe. W artykule zostały omówione zależne od tropomiozyny mechanizmy regulacji oddziaływań aktyny z niektórymi miozynami oraz z Arp2/3 i kofiliną - białkami, które inicjują rozgałęzianie, polimeryzację i depolimeryzację filamentów aktynowych.
Actin is a universal protein highly conserved in evolution. In cells, actin exists in equilibrium between a monomeric and filamentous form. In spite of a conservative structure, actin plays amazingly versatile functions. This is possible due to its interactions with numerous actin-binding proteins, among them with myosin motors and proteins regulating dynamic polymerization and depolymeriation of actin. Tropomyosins, superhelical proteins, which polymerize along the filament and stabilize actin by preventing its depolymerization, are superior actin filament regulators. Tropomyosins control the access and activity of various actin-binding proteins. Tropomyosins act thus as actin “gate-keepers” which control actin interactions leading to the segregation of actin-binding proteins into specific cell compartments where they perform specific cellular functions. This article discusses tropomyosin-dependent mechanisms of regulation of actin interactions with some myosins as well as Arp2/3 and cofilin - the proteins, which initiate branching, polymerization and depolymerization of actin filaments.
Źródło:
Kosmos; 2018, 67, 1; 31-41
0023-4249
Pojawia się w:
Kosmos
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
The role of actin and microtubule networks in plasmid DNA intracellular trafficking
Autorzy:
Ondřej, Vladan
Lukášová, Emilie
Falk, Martin
Kozubek, Stanislav
Powiązania:
https://bibliotekanauki.pl/articles/1041059.pdf
Data publikacji:
2007
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
cytoplasmic trafficking
microtubules
plasmid DNA-lipid complexes
actin filaments
Opis:
This work is focused on the function of the microtubule and actin networks in plasmid DNA transport during liposomal transfection. We observed strong binding of plasmid DNA-lipid complexes (lipoplexes) to both networks and directional long-range motion of these lipoplexes along the microtubules. Disruption of either of these networks led to the cessation of plasmid transport to the nucleus, a decreased mobility of plasmids, and accumulation of plasmid DNA in large aggregates at the cell periphery. Our findings show an indispensable but different role of both types of cytoskeleton, actin and microtubular, in the processes of gene delivery.
Źródło:
Acta Biochimica Polonica; 2007, 54, 3; 657-663
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Effect of Rho-associated kinase inhibition on actin cytoskeleton structure and calcium response in glioma C6 cells
Autorzy:
Targos, Berenika
Pomorski, Paweł
Krzemiński, Patryk
Barańska, Jolanta
Rędowicz, Maria
Kłopocka, Wanda
Powiązania:
https://bibliotekanauki.pl/articles/1041182.pdf
Data publikacji:
2006
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
glioma C6
actin cytoskeleton
RhoA
ROCK
calcium transients
Opis:
The role of actin cytoskeleton functional state in glioma C6 cell morphology and calcium signaling was investigated through modification of myosin II activity by blocking Rho-associated kinase with the specific inhibitor Y-27632. Treatment of glioma C6 cells with ROCK inhibitor resulted in actin cytoskeleton reorganization and also in the changed shape and distribution of mitochondria. Changes in the distribution of ER, the main calcium store in glioma C6 cells, were not visible. The inhibition of myosin II activity influences the first phase of calcium signaling evoked by agonist, and both phases of thapsigargin-evoked calcium response. We suggest that the observed increase in Ca2+ release from intracellular stores induced by IP3 formation as well as inhibition of SERCA ATPase is at least in part related to severely affected mitochondria. Enhancement of capacitative calcium entry evoked by thapsigargin is probably associated with the reorganization of the acto-myosin II system. ATP-induced calcium response presents no changes in the second phase. We observed that ATP stimulation of Y-27632 pretreated cells leads to immediate morphological rearrangement of glioma C6 cells. It is a consequence of actin cytoskeleton reorganization: formation of stress fibers and relocation of phosphorylated myosin II to actin filaments. It seems that the agonist-evoked strong calcium signal may be sufficient for myosin II activation and the stress fiber organization. This is the first work showing the dependence between the functional state of the acto-myosin II system and calcium signaling stressing the reversible character of this relationship.
Źródło:
Acta Biochimica Polonica; 2006, 53, 4; 825-831
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
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