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    Wyświetlanie 1-6 z 6
    Tytuł:
    The usefulness of D-dimer in diagnosis and prediction of venous thromboembolism in patients with abdominal malignancy
    Autorzy:
    Kwietniak, Marcin
    Al-Amawi, Tariq
    Błaszkowski, Tomasz
    Sulżyc-Bielicka, Violetta
    Kładny, Józef
    Powiązania:
    https://bibliotekanauki.pl/articles/1393589.pdf
    Data publikacji:
    2017
    Wydawca:
    Index Copernicus International
    Tematy:
    D-dimer
    venous thromboembolic disease
    cancer
    Opis:
    The aim: of the study was to evaluate the usefulness of D-dimer evaluation in the diagnosis and prediction of venous thromboembolism (VTE) of lower extremities in patients operated on for abdominal tumors depending on the chosen cut-off point for this parameter. Material and methods: We included 150 patients operated on for abdominal cancer in our department between October 2014 and June 2016. In these patients, concentration of D-dimer was determined, medical histories were taken, and physical examinations were performed. Ultrasound exams of the veins of the lower limbs were performed three times in every patient in order to confirm or exclude VTE. Results: When a standard cut-off point (500 ng/ml) was used, in 46% of cancer patients D-dimer values were elevated despite the lack of VTE. We did not detect any influence of cancer stage on the value of D-dimer. However, if cut-off point was 1440 ng/ml, which has been suggested in the literature, only 14% of patients were false positive. When the upper cut-off value for D-dimer was raised, the effect of cancer stage on the value of this parameter could be seen. Conclusion: The concentration of D-dimer is often elevated in patients with active cancer, but is not a sufficient criterion for diagnosis of VTE. The concentration of D-dimer before surgery does not determine the risk of postoperative thromboembolic complications. This is undoubtedly related to the widespread use of effective thromboprophylaxis. According to the literature, ultrasound is the optimum method for detection of VTE in surgically treated cancer patients. The effect of cancer stage on the value of D-dimer is revealed only when the cut-off point in this group is 1440 ng/ml, instead of 500 ng/ml which is used for the general population.
    Źródło:
    Polish Journal of Surgery; 2017, 89, 3; 27-30
    0032-373X
    2299-2847
    Pojawia się w:
    Polish Journal of Surgery
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Treatment of lower limb trophic ulcers using hyperbaric oxygenation
    Autorzy:
    Kulesza, T.
    Mitrut, T.
    Jojczuk, M.
    Jaholkowski, L.
    Nodalski, A.
    Prystupa, A.
    Powiązania:
    https://bibliotekanauki.pl/articles/3341.pdf
    Data publikacji:
    2014
    Wydawca:
    Instytut Medycyny Wsi
    Tematy:
    human disease
    venous disease
    treatment
    lower limb
    trophic ulcer
    hyperbaric oxygenation
    hyperbaric treatment
    Źródło:
    Journal of Pre-Clinical and Clinical Research; 2014, 08, 1
    1898-2395
    Pojawia się w:
    Journal of Pre-Clinical and Clinical Research
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    New Method of Forced Implantation of Permanent Catheters for Hemodialysis into Critically Stenosed or Occluded Central Veins
    Autorzy:
    Przywara, Stanisław
    Iłżecki, Marek
    Terlecki, Piotr
    Zubilewicz, Tomasz
    Powiązania:
    https://bibliotekanauki.pl/articles/1395845.pdf
    Data publikacji:
    2014-12-18
    Wydawca:
    Index Copernicus International
    Tematy:
    vascular access for hemodialysis
    permanent catheters for hemodialysis
    central venous occlusive disease
    Opis:
    The aim of the study was to report a novel technique of forced implantation of catheters for hemodialysis into critically stenosed or occluded central veins, without preceding angioplasty or stenting. Material and methods. Sixteen patients with central venous occlusive disease, requiring urgent hemodialysis underwent this procedure. Catheterization of stenosis - occlusion was initially performed with soft guidewire, subsequently exchanged to stiff guidewire. Forced insertion of dilators, peel-off sheath throughout the stenosis or occlusion and finally implantation of the catheter completed the procedure. Our technique does not require pre-procedural angioplasty or stent deployment. Results. In all patients postoperative hemodialysis was managed with satisfactory adequacy. No early or late complications related to the procedure occurred. We did not observe any clinically significant aggravation of symptoms of central vein stenosis or occlusion. Complications, not-related to the procedure included one, late skin entry site infection and one, late catheter thrombosis. These were managed without the necessity of catheter exchange. Conclusions. Our technique of forced implantation of catheters for hemodialysis into critically stenosed or occluded central veins without previous balloon predilatation or stenting is simple and diminishes the total cost of the procedure. Provides quick vascular access for hemodialysis in life threatening situations.
    Źródło:
    Polish Journal of Surgery; 2014, 86, 9; 405-409
    0032-373X
    2299-2847
    Pojawia się w:
    Polish Journal of Surgery
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Zakrzepica w chorobie nowotworowej
    Thrombosis in cancer
    Autorzy:
    Chojnacki, Tomasz
    Rzepecki, Piotr
    Powiązania:
    https://bibliotekanauki.pl/articles/1033769.pdf
    Data publikacji:
    2015
    Wydawca:
    Medical Communications
    Tematy:
    cancer
    deep vein thrombosis
    pulmonary embolism
    venous thromboembolic disease
    żylna choroba zakrzepowo-zatorowa
    choroba nowotworowa
    zakrzepica żył głębokich
    zatorowość płucna
    Opis:
    Malignant tumours are among the strongest risk factors for venous thromboembolism. The probability scores for deep vein thrombosis and pulmonary embolism, which we use in our everyday practice, have not yet been validated in patients with cancer, which is why they should be used with caution. Prevention of thrombosis should always be implemented in patients undergoing surgery and most patients treated conservatively, which results from the application of appropriate probability scores assessing the risk of thrombosis in these patients. The prevention method should be adjusted individually depending on the characteristics of the patient and the existence of contraindications to the use of given methods, bearing in mind their availability, cost and ability to monitor the anticoagulant effect. Treatment of venous thromboembolism in patients with cancer is different from treating it in patients with no concomitant tumour. These differences relate to both the type of treatment (anticoagulant drug selection and dosage) and its duration. Low-molecular-weight heparin is the preferred form of both initial and long-term treatment, which should last at least 6 months. Both oncologists and other health care professionals working in cancer teams should make sure at each time that the patient has at least minimal knowledge about the symptoms ensuring early detection of thrombosis. Good communication with the patient considerably facilitates effective prevention and treatment.
    Nowotwory złośliwe należą do najsilniejszych czynników ryzyka rozwoju żylnej choroby zakrzepowo-zatorowej. Skale oceny prawdopodobieństwa zakrzepicy żył głębokich i zatorowości płucnej, którymi się posługujemy w codziennej praktyce, nie zostały dotychczas zwalidowane u pacjentów z chorobą nowotworową, dlatego należy z nich korzystać z dużą ostrożnością. Profilaktykę przeciwzakrzepową powinno się zastosować każdorazowo w przypadku osób poddawanych zabiegom chirurgicznym oraz u większości leczonych zachowawczo, co wynika z odpowiednich skal oceny ryzyka zakrzepicy u tych chorych. Metodę profilaktyki należy dobierać indywidualnie w zależności od charakterystyki pacjenta oraz istnienia przeciwwskazań do zastosowania danych metod, mając na względzie ich dostępność, koszty oraz możliwości monitorowania efektu przeciwkrzepliwego. Leczenie żylnej choroby zakrzepowo-zatorowej u pacjentów z chorobą nowotworową różni się od leczenia pacjentów bez współistniejącego nowotworu. Różnice te odnoszą się zarówno do rodzaju leczenia (wybór leku przeciwkrzepliwego, jego dawkowanie), jak i czasu trwania terapii. Heparyna drobnocząsteczkowa jest preferowaną formą leczenia wstępnego, a także długoterminowego, które powinno trwać co najmniej 6 miesięcy. Onkolodzy wraz z pozostałym personelem służby zdrowia pracującym w teamach onkologicznych powinni każdorazowo upewnić się, że pacjent posiada przynajmniej minimum wiedzy o objawach umożliwiających wczesne wykrycie zakrzepicy. Dobra komunikacja z pacjentem zdecydowanie ułatwia prowadzenie skutecznej profilaktyki i leczenia.
    Źródło:
    Pediatria i Medycyna Rodzinna; 2015, 11, 1; 48-67
    1734-1531
    2451-0742
    Pojawia się w:
    Pediatria i Medycyna Rodzinna
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Methylenetetrahydrofolate reductase (MTHFR-677 and MTHFR-1298) genotypes and haplotypes and plasma homocysteine levels in patients with occlusive artery disease and deep venous thrombosis
    Autorzy:
    Spiroski, Igor
    Kedev, Sashko
    Antov, Slobodan
    Arsov, Todor
    Krstevska, Marija
    Dzhekova-Stojkova, Sloboda
    Bosilkova, Gordana
    Kostovska, Stojanka
    Trajkov, Dejan
    Petlichkovski, Aleksandar
    Strezova, Ana
    Efinska-Mladenovska, Olivija
    Spiroski, Mirko
    Powiązania:
    https://bibliotekanauki.pl/articles/1040721.pdf
    Data publikacji:
    2008
    Wydawca:
    Polskie Towarzystwo Biochemiczne
    Tematy:
    MTHFR-677
    plasma total homocysteine
    occlusive artery disease
    MTHFR-1298
    deep venous thrombosis
    Opis:
    The aim was to investigate different genotypes and haplotypes of methylenetetrahydrofolate reductase (MTHFR-677, -1298) and plasma concentration of total homocysteine (tHcy) in Macedonian patients with occlusive artery disease (OAD) and deep venous thrombosis (DVT). Investigated groups consists of 80 healthy, 74 patients with OAD, and 63 patients with DVT. Plasma tHcy was measured with Microplate Enzyme Immunoassay. Identification of MTHFR genotypes and haplotypes was done with CVD StripAssay. The probability level (P-value) was evaluated by the Student's t-test. Plasma concentration of tHcy in CC and CT genotypes of MTHFR C677T was significantly increased in patients with OAD and in patients with DVT. Plasma concentration of tHcy in AC genotype of MTHFR A1298C was increased in patients with OAD and in patients with DVT. Plasma concentration of tHcy was significantly increased in AA genotype of patients with OAD, but not in patients with DVT. We found a significant increase of plasma tHcy in patients with OAD in comparison with healthy respondents for normal:heterozygote (CC:AC), heterozygote:normal (CT:AA), and heterozygote:heterozygote (CT:AC) haplotypes. Plasma concentration of tHcy in patients with DVT in comparison with healthy respondents was significantly increased for normal:normal (CC:AA), normal heterozygote (CC:AC), and heterozygote:heterozygote (CT:AC) haplotypes. We conclude that MTHFR C677T and MTHFR A1289C genotypes and haplotypes are connected with tHcy plasma levels in Macedonian patients with OAD and DVT.
    Źródło:
    Acta Biochimica Polonica; 2008, 55, 3; 587-594
    0001-527X
    Pojawia się w:
    Acta Biochimica Polonica
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Acid-base balance parameters and a value of anion gap of arterial and venous blood in Malopolski horses
    Autorzy:
    Slawuta, P.
    Noszczyk-Nowak, A.
    Nowakowski, H.
    Powiązania:
    https://bibliotekanauki.pl/articles/32496.pdf
    Data publikacji:
    2010
    Wydawca:
    Polska Akademia Nauk. Czytelnia Czasopism PAN
    Tematy:
    acid-base balance
    anion gap
    arterial blood
    venous blood
    Malopolska breed
    horse
    pH
    hydrogen carbonate concentration
    carbon dioxide molecule pressure
    respiratory system
    animal disease
    liver
    Opis:
    The comparative study of the acid-base balance (ABB) parameters has been performed on 20 clinically healthy mature Małopolski horses. An arterial blood sample from the facial artery and a sample of venous blood from the external cervical vein were colected from each animal. In the samples tested, the blood pH, pCO₂, tCO₂, HCO₃-, concentration of Na+, K+, Cl-, and a value of the anion gap were determined. The difference among pCO₂, tCO₂, and HCO₃ - in both samples tested was statistically significant, whereas the pH of the arterial blood and the pH of the venous blood did not differ significantly. The anion gap in both types of blood did not differ significantly. Conclusions: 1) ABB parameters such as pCO₂, HCO₃-, and tCO₂ determined in the arterial and venous blood of the Małopolski horses differ from each other significantly. 2) In spite of the lack of the differences between pH of the arterial and venous blood, the ABB parameters in horses should be determined in the arterial blood, because the comparative study performed proves that the analysis of the ABB parameters determined for the venous blood of a healthy horse may lead to a wrong diagnosis of the compensated respiratory acidosis. 3) The mean value of anion gap in horses aged 8-12 years amounts to 20.9 mmol/l for the arterial blood and 19.93 for the venous blood; the difference between the two values is not statistically significant.
    Źródło:
    Polish Journal of Veterinary Sciences; 2010, 13, 4
    1505-1773
    Pojawia się w:
    Polish Journal of Veterinary Sciences
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
      Wyświetlanie 1-6 z 6

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