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Wyszukujesz frazę "triiodothyronine" wg kryterium: Temat


Wyświetlanie 1-4 z 4
Tytuł:
Effect of triiodothyronine on phospholipid metabolism in skeletal muscles of the rat
Autorzy:
Zendzian-Piotrowska, M.
Gorska, M.
Dworakowski, W.
Gorski, J.
Powiązania:
https://bibliotekanauki.pl/articles/69449.pdf
Data publikacji:
2000
Wydawca:
Polskie Towarzystwo Fizjologiczne
Tematy:
abdominal aorta
phospholipid metabolism
blood
triiodothyronine
thyroid hormone
rat
skeletal muscle
Źródło:
Journal of Physiology and Pharmacology; 2000, 51, 1
0867-5910
Pojawia się w:
Journal of Physiology and Pharmacology
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Effect of triiodothyronine on the content of phospholipids in the rat liver nuclei
Autorzy:
Bucki, R.
Gorska, M.
Zendzian-Piotrowska, M.
Gorski, J.
Powiązania:
https://bibliotekanauki.pl/articles/69507.pdf
Data publikacji:
2000
Wydawca:
Polskie Towarzystwo Fizjologiczne
Tematy:
phosphatidylethanolamine
serum
cardiolipin
triiodothyronine
rat
phosphatidylinositol
phospholipid
saline
sphingomyelin
liver
nucleus
phosphatidylserine
phosphatidylcholine
Źródło:
Journal of Physiology and Pharmacology; 2000, 51, 3
0867-5910
Pojawia się w:
Journal of Physiology and Pharmacology
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Thyroid hormones and their receptors in the regulation of cell proliferation
Autorzy:
Puzianowska-Kuznicka, Monika
Pietrzak, Maciej
Turowska, Olga
Nauman, Alicja
Powiązania:
https://bibliotekanauki.pl/articles/1041151.pdf
Data publikacji:
2006
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
thyroid hormone nuclear receptors (TRs)
oncoproteins
triiodothyronine (T3)
proliferation
mitogens
Opis:
In the present work, we have reviewed data showing that triiodothyronine and its nuclear receptors modify expression of different genes/proteins involved in cell cycle control beginning from growth factors (such as EGF and TGF-β), to cell surface receptors (EGFR), as well as proteins acting at the cell membrane (Ras), various transcription factors (c-Fos, c-Myc, E2F1), cyclins, Cip/Kip family of cdk2 inhibitors, and p53 inhibitor Mdm2 (Table 1). We have shown how TRs are also able to modify the fate of a cell, thanks to their ability to form complexes with other transcription factors such as p53 - a key regulator of apoptosis and proliferation. Available data show that the function of thyroid hormones and of their receptors on cell proliferation is not homogenous. In fact, it strongly depends on the cell type, its developmental state (progenitor or differentiated), its patho-physiological state (normal or tumor cell), and the so-called 'cellular context'. Therefore, it is not possible to uniformly recommend T3 treatment or T3 depletion to stop or initiate proliferation of all cell types. Instead, a very individual and careful action should be considered.
Źródło:
Acta Biochimica Polonica; 2006, 53, 4; 641-650
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Thyroid hormones in the cerebrospinal fluid of the third ventricle of adult female sheep during different periods of reproductive activity
Autorzy:
Skipor, J.
Misztal, T.
Szczepkowska, A.
Powiązania:
https://bibliotekanauki.pl/articles/30646.pdf
Data publikacji:
2010
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
thyroid hormone
cerebrospinal fluid
ventricle
adult
female
sheep
reproductive activity
reproductive period
ewe
thyroxine
triiodothyronine
breeding season
anoestrus
Opis:
Thyroid hormones (THs) are obligatory for transition from breeding season to anestrus in sheep. In this process, THs act during a very limited time of the year and primarily within the brain. In ewes chronically equipped for sampling cerebrospinal fluid (CSF) from the third ventricle, we have characterized the concentrations of total and free thyroxine (T4), triiodothyronine (T3), and total reverse T3 (rT3) in the CSF during breeding season, anestrus and during a critical period required for transition to anestrus (December-March). The total T4, T3, rT3 and free T3 average concentrations (± SEM) in CSF were 1.5 ± 0.07 ng/ml, 14.5 ± 1.2 pg/ml, 43 ± 7.4 pg/ml, and 0.6 ± 0.05 pg/ml, respectively, and all were significantly lower (p < 0.001) than in blood plasma except free T4 (12.6 ± 1.1 pg/ml), which was similar to that in plasma. There was a seasonal trend (p < 0.05) in the concentration of total T3 (highest in December) and free T4 (highest in November) in the CSF that does not follow that in blood plasma. During the period of transition to anestrus the CSF total T3/TT4 molar ratio and free T3/ T4 ratio were significantly lower (p < 0.05 and p < 0.01, respectively) than in blood plasma, while the total rT3/T4 ratio was significantly higher (p < 0.01) at the end of this period (March). Additionally, the CSF total rT3 concentrations were also significantly correlated with the CSF total T4 levels (r = 0.57; p < 0.05). In conclusion, the CSF in sheep may serve as a considerable source of thyroid hormones for neuroendocrine events. The lack of significant changes in THs concentrations in the CSF during the period of transition to anestrus indicate that neither seasonal changes of THs circulating in the blood plasma nor THs circulating in the CSF actively drive the transition to anestrus.
Źródło:
Polish Journal of Veterinary Sciences; 2010, 13, 4
1505-1773
Pojawia się w:
Polish Journal of Veterinary Sciences
Dostawca treści:
Biblioteka Nauki
Artykuł
    Wyświetlanie 1-4 z 4

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