Temat: thyroid hormone - Katalog OPAC zbiorów

Skocz do pozycji: 1.

Tytuł:: Effects of polybrominated diphenyl ethers on thyroid hormone, neurodevelopment and fertility in rodents and humans
Autorzy:: Czerska, Marta
Zieliński, Marek
Kamińska, Joanna
Ligocka, Danuta
Powiązania:: https://bibliotekanauki.pl/articles/2179114.pdf
Data publikacji:: 2013-08-01
Wydawca:: Instytut Medycyny Pracy im. prof. dra Jerzego Nofera w Łodzi
Tematy:: PBDEs
thyroid hormone
neurodevelopment
fertility
rodents
humans
Opis:: Polybrominated diphenyl ethers (PBDEs) are used as flame retardants. Due to their widespread use in many consumer products, PBDEs can be found in food as well as in the environment. Their presence has also been found in the human serum, human adipose tissue and human breast milk. Results of experimental studies suggest that the presence of PBDE in the environment is not neutral to our health. In rats and mice exposed to PBDE disturbances in thyroid hormone homeostasis and reproductive system such as changes in reproductive organs weight and disorders in sperm motility and motion were found. In rodents, pre- and postnatal exposure to PBDE can cause neurobehavioral effects. Also in humans disturbances in thyroid hormone system, weight of reproductive organs and concentrations of sex hormones associated with PBDEs serum concentrations were found. Exposure to PBDEs during pregnancy may lead to slower mental and psychomotor development in infants. In this paper the results of previous animal a nd human studies are reviewed.
Źródło:: International Journal of Occupational Medicine and Environmental Health; 2013, 26, 4; 498-510
1232-1087
1896-494X
Pojawia się w:: International Journal of Occupational Medicine and Environmental Health
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 2.

Tytuł:: Oxidative stress and antioxidants markers in individuals with thyroid hormones dysfunction
Autorzy:: Omon, Emmanuel Akokhamen
Ajay, Olawale David
Powiązania:: https://bibliotekanauki.pl/articles/29520465.pdf
Data publikacji:: 2023-12-31
Wydawca:: Uniwersytet Rzeszowski. Wydawnictwo Uniwersytetu Rzeszowskiego
Tematy:: antioxidants
dysfunction
malondialdehyde
oxidative stress
thyroid hormone
Opis:: Introduction and aim. Thyroid hormone abnormalities have been associated with oxidative changes in human beings. The aim of the study was to evaluate the oxidative stress marker and antioxidants status in individuals with thyroid hormone dysfunction in Ekiti State. Material and methods. A total of eighty samples were recruited in this study comprising forty subjects with thyroid hormones dysfunction and forty apparently healthy controls. Malondialdehyde (MDA), reduced glutathione (GSH) and catalase were determined spectrophotometerically. Results. MDA was non-significantly higher (p>0.05) in subjects (4.33±0.84 nmol/mL) compared with control (4.12±0.63 nmol/mL), catalase was non-significantly higher (p>0.05) in subjects (199.36±20.21 µm/mL) compared with control (181.55±16.61 µm/mL), while GSH was significantly lower (p<0.05) in subjects (79.31±10.12 µmol/mL) compared with control (127.21±7.29 µmol/mL). Conclusion. It can be concluded that the increase in the reactive oxygen species accompanied with impairment of the antioxidant system occurs in patients with thyroid hormone dysfunction. Hypothyroidism and hyperthyroidism induces disequilibrium of the oxidative/anti-oxidative balance that can lead to subsequent development of inflammation and associated diseases.
Źródło:: European Journal of Clinical and Experimental Medicine; 2023, 4; 768-775
2544-2406
2544-1361
Pojawia się w:: European Journal of Clinical and Experimental Medicine
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 3.

Tytuł:: Plasma thyroid hormones and corticosterone levels in blood of chicken embryos and post hatch chickens exposed during incubation to 1800 MHz electromagnetic field
Autorzy:: Pawlak, Krzysztof
Sechman, Andrzej
Nieckarz, Zenon
Powiązania:: https://bibliotekanauki.pl/articles/2178802.pdf
Data publikacji:: 2014-01-01
Wydawca:: Instytut Medycyny Pracy im. prof. dra Jerzego Nofera w Łodzi
Tematy:: electromagnetic fields
mobile phone
thyroid hormone
corticosterone
chicken embryo
Opis:: Introduction: This study attempted to determine the effect of a 1800 MHz electromagnetic field (EMF) (only carrier frequency) on thyroxine (T₄), triiodothyronine (T₃) and corticosterone (CORT) concentrations in the blood plasma of chick embryos, and to investigate the effect of electromagnetic field (EMF) exposure during embryogenesis on the level of these hormones in birds that are ready for slaughter. Material and Methods: Throughout the incubation period, embryos from the experimental group were exposed to a 1800 MHz EMF with power density of 0.1 W/m², 10 times during 24 h for 4 min. Blood samples were collected to determine T₄, T₃ and CORT concentrations on the 12th (E12) and 18th (E18) day of incubation, from newly hatched chicks (D1) and from birds ready for slaughter (D42). Results: The experiment showed that T₄ and T₃ concentrations decreased markedly and CORT levels increased in the embryos and in the newly hatched chicks exposed to EMF during embryogenesis. However, no changes were found in the level of the analyzed hormones in the birds ready for slaughter. Differences in T₄ and T₃ plasma concentrations between the EMF-exposed group and the embryos incubated without additional EMF were the highest in the newly hatched chicks, which may be indicative of the cumulative effect of electromagnetic field on the hypothalamo-pituitary-thyroid axis (HPT). Discussion: The obtained results suggest that additional 1800 MHz radio frequency electromagnetic field inhibits function of HPT axis, however, it stimulates hypothalamo- pituitary-adrenal axis by inducing adrenal steroidogenic cells to synthesize corticosterone. Further investigations are needed to elucidate the mechanisms by which radio EMFs affect HPT and HPA axis function in the chicken embryos.
Źródło:: International Journal of Occupational Medicine and Environmental Health; 2014, 27, 1; 114-122
1232-1087
1896-494X
Pojawia się w:: International Journal of Occupational Medicine and Environmental Health
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 4.

Tytuł:: Fever induced oxidative stress: the effect on thyroid status and the 5-monodeiodinase activity, protective role of selenium and vitamin E
Autorzy:: Brzezinska-Slebodzinska, E.
Powiązania:: https://bibliotekanauki.pl/articles/70517.pdf
Data publikacji:: 2001
Wydawca:: Polskie Towarzystwo Fizjologiczne
Tematy:: vitamin E
5'-monodeiodinase activity
oxidative stress
thyroid hormone
selenium
Źródło:: Journal of Physiology and Pharmacology; 2001, 52, 2
0867-5910
Pojawia się w:: Journal of Physiology and Pharmacology
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 5.

Tytuł:: Thyroid hormones and their receptors in the regulation of cell proliferation
Autorzy:: Puzianowska-Kuznicka, Monika
Pietrzak, Maciej
Turowska, Olga
Nauman, Alicja
Powiązania:: https://bibliotekanauki.pl/articles/1041151.pdf
Data publikacji:: 2006
Wydawca:: Polskie Towarzystwo Biochemiczne
Tematy:: thyroid hormone nuclear receptors (TRs)
oncoproteins
triiodothyronine (T3)
proliferation
mitogens
Opis:: In the present work, we have reviewed data showing that triiodothyronine and its nuclear receptors modify expression of different genes/proteins involved in cell cycle control beginning from growth factors (such as EGF and TGF-β), to cell surface receptors (EGFR), as well as proteins acting at the cell membrane (Ras), various transcription factors (c-Fos, c-Myc, E2F1), cyclins, Cip/Kip family of cdk2 inhibitors, and p53 inhibitor Mdm2 (Table 1). We have shown how TRs are also able to modify the fate of a cell, thanks to their ability to form complexes with other transcription factors such as p53 - a key regulator of apoptosis and proliferation. Available data show that the function of thyroid hormones and of their receptors on cell proliferation is not homogenous. In fact, it strongly depends on the cell type, its developmental state (progenitor or differentiated), its patho-physiological state (normal or tumor cell), and the so-called 'cellular context'. Therefore, it is not possible to uniformly recommend T3 treatment or T3 depletion to stop or initiate proliferation of all cell types. Instead, a very individual and careful action should be considered.
Źródło:: Acta Biochimica Polonica; 2006, 53, 4; 641-650
0001-527X
Pojawia się w:: Acta Biochimica Polonica
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 6.

Tytuł:: Effect of triiodothyronine on phospholipid metabolism in skeletal muscles of the rat
Autorzy:: Zendzian-Piotrowska, M.
Gorska, M.
Dworakowski, W.
Gorski, J.
Powiązania:: https://bibliotekanauki.pl/articles/69449.pdf
Data publikacji:: 2000
Wydawca:: Polskie Towarzystwo Fizjologiczne
Tematy:: abdominal aorta
phospholipid metabolism
blood
triiodothyronine
thyroid hormone
rat
skeletal muscle
Źródło:: Journal of Physiology and Pharmacology; 2000, 51, 1
0867-5910
Pojawia się w:: Journal of Physiology and Pharmacology
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 7.

Tytuł:: Thyroid hormone and thyreotropin (TSH) association with densitometric parameters in children
Autorzy:: Porwik, E.
Matusik, P.
Drzyzdzyk, K.
Powiązania:: https://bibliotekanauki.pl/articles/333097.pdf
Data publikacji:: 2009
Wydawca:: Uniwersytet Śląski. Wydział Informatyki i Nauki o Materiałach. Instytut Informatyki. Zakład Systemów Komputerowych
Tematy:: tyreotropina
hormon tarczycy
densytometria
gęstość mineralna kości
dzieci
thyrotropin
thyroid hormone
densitometry
bone mineral density
children
Opis:: The influence of TSH on bones is still vastly unknown and the information that is known is considered controversial. This important relationship has not been studied in detail. The aim of our research was to assess the correlation between TSH, thyroid hormone and bone mineral density in children measured by DXA scanning. Our study group included 36 children (16 girls and 20 boys) mean age 12.9 š 3.3 years. Basic anthropometrical measurements were performed (height, weight, body mass index-BMI), in all subjects. Blood was collected and measured for TSH and FT4. Bone mineral density of lumbar spine (L2-L4 BMD) and total body (Total Body BMD) were measured by DXA and expressed as bone mineral content (BMC [g]) and bone mineral density (BMD [g/cm2]). BMD Z-Score was also calculated. Correlation between the parameters obtained by DXA and anthropometrical data, TSH and thyroid hormone concentration were calculated. A statistically significant positive correlation was observed between height, weight and BMI and BMD which was calculated. Weight and BMI also had a statically significant correlation with Z-Score and total bone mineral content (BMC – expressed in grams). There was a statistically significant positive correlation between TSH level and Z-Score for both L2-L4 lumbar spine and for total body. TSH did not correlate significantly with BMD [g/cm2] and BMC [g]. FT4 was negatively and significantly correlated with Z-Score for both L2-L4 lumbar spine and for total body. There was also no significant correlation between FT4 and BMD [g/cm2] and BMC [g]. Conclusion: 1. Thyroid stimulating-hormone (TSH) appears to be associated with maintenance of bone mineral density in children. 2. BMD Z-Score especially from L2-L4 lumbar spine assessed by DXA scanning is correlated best with hormonal and biochemical factors potentially influencing bone mineralization in children.
Źródło:: Journal of Medical Informatics & Technologies; 2009, 13; 141-144
1642-6037
Pojawia się w:: Journal of Medical Informatics & Technologies
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 8.

Tytuł:: Thyroid hormones in the cerebrospinal fluid of the third ventricle of adult female sheep during different periods of reproductive activity
Autorzy:: Skipor, J.
Misztal, T.
Szczepkowska, A.
Powiązania:: https://bibliotekanauki.pl/articles/30646.pdf
Data publikacji:: 2010
Wydawca:: Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:: thyroid hormone
cerebrospinal fluid
ventricle
adult
female
sheep
reproductive activity
reproductive period
ewe
thyroxine
triiodothyronine
breeding season
anoestrus
Opis:: Thyroid hormones (THs) are obligatory for transition from breeding season to anestrus in sheep. In this process, THs act during a very limited time of the year and primarily within the brain. In ewes chronically equipped for sampling cerebrospinal fluid (CSF) from the third ventricle, we have characterized the concentrations of total and free thyroxine (T4), triiodothyronine (T3), and total reverse T3 (rT3) in the CSF during breeding season, anestrus and during a critical period required for transition to anestrus (December-March). The total T4, T3, rT3 and free T3 average concentrations (± SEM) in CSF were 1.5 ± 0.07 ng/ml, 14.5 ± 1.2 pg/ml, 43 ± 7.4 pg/ml, and 0.6 ± 0.05 pg/ml, respectively, and all were significantly lower (p < 0.001) than in blood plasma except free T4 (12.6 ± 1.1 pg/ml), which was similar to that in plasma. There was a seasonal trend (p < 0.05) in the concentration of total T3 (highest in December) and free T4 (highest in November) in the CSF that does not follow that in blood plasma. During the period of transition to anestrus the CSF total T3/TT4 molar ratio and free T3/ T4 ratio were significantly lower (p < 0.05 and p < 0.01, respectively) than in blood plasma, while the total rT3/T4 ratio was significantly higher (p < 0.01) at the end of this period (March). Additionally, the CSF total rT3 concentrations were also significantly correlated with the CSF total T4 levels (r = 0.57; p < 0.05). In conclusion, the CSF in sheep may serve as a considerable source of thyroid hormones for neuroendocrine events. The lack of significant changes in THs concentrations in the CSF during the period of transition to anestrus indicate that neither seasonal changes of THs circulating in the blood plasma nor THs circulating in the CSF actively drive the transition to anestrus.
Źródło:: Polish Journal of Veterinary Sciences; 2010, 13, 4
1505-1773
Pojawia się w:: Polish Journal of Veterinary Sciences
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 9.

Tytuł:: Hormonal changes in dairy cows during periparturient period
Zmiany hormonalne u krów mlecznych w okresie okołoporodowym
Autorzy:: Kurpińska, A.
Skrzypczak, W.
Powiązania:: https://bibliotekanauki.pl/articles/2615881.pdf
Data publikacji:: 2019
Wydawca:: Zachodniopomorski Uniwersytet Technologiczny w Szczecinie. Wydawnictwo Uczelniane ZUT w Szczecinie
Tematy:: dairy cow
hormonal change
periparturient period
prostaglandin F2 alpha
prolactin
human growth hormone
oxytocin
progesterone
estrogen
androgen
glycoprotein
gonadotrophin releasing hormone
luteinizing hormone
follicle stimulating hormone
thyroid hormone
cortisol
insulin
Źródło:: Acta Scientiarum Polonorum. Zootechnica; 2019, 18, 4; 13-21
1644-0714
Pojawia się w:: Acta Scientiarum Polonorum. Zootechnica
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 10.

Tytuł:: Microbiome impact on metabolism and function of sex, thyroid, growth and parathyroid hormones
Autorzy:: Kunc, Michał
Gabrych, Anna
Witkowski, Jacek
Powiązania:: https://bibliotekanauki.pl/articles/1038795.pdf
Data publikacji:: 2016
Wydawca:: Polskie Towarzystwo Biochemiczne
Tematy:: microbiome
lipopolysaccharide
estrogens
thyroid hormones
growth hormone
Opis:: Commensal bacteria and their genes associated with host are known as microbiome. In recent years, microbial influence on host endocrine system has been under detailed investigation. The role of microbiome in the pathogenesis of insulin resistance and obesity, the function of hypothalamic-pituitary-adrenal axis and secretion of hormones regulating appetite is well described in world literature. In this article we discuss poorly reviewed issues: the microbiome role in modulation of non-peptide (sex and thyroid) and peptide (growth hormone and parathyroid hormone) functions. Understanding complex bidirectional relations between host endocrine system and bacteria is of fundamental importance to understanding microbial impact on host reproduction, risk of endocrine-related cancers, pathogenesis of non-thyroidal illness syndrome, growth failure in children and hormonal changes during chronic kidney disease. This article also highlights effects of dietary compounds on microbiome composition and bacterial enzymes activity, and thus host hormonal status.
Źródło:: Acta Biochimica Polonica; 2016, 63, 2; 189-201
0001-527X
Pojawia się w:: Acta Biochimica Polonica
Dostawca treści:: Biblioteka Nauki

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