Temat: test UMU - Katalog OPAC zbiorów

Skocz do pozycji: 1.

Tytuł:: Detection of genotoxicity of atmospheric particles using a high-throughput microplate umu-test system.
Autorzy:: Funasaka, Kunihiro
Kitano, Masaaki
Nakama, Akihiko
Yoshikura, Taro
Oda, Yoshimitsu
Powiązania:: https://bibliotekanauki.pl/articles/1043678.pdf
Data publikacji:: 2003
Wydawca:: Polskie Towarzystwo Biochemiczne
Tematy:: Salmonella typhimurium NM3009
umu-microplate test
nitroarenes
genotoxicity
atmospheric particles
Salmonella typhimurium NM2009
Opis:: A previously developed and highly sensitive umu-microplate test system based on the nitroreductase- and O-acetyltransferase-overproducing strain Salmonella typhimurium NM3009 and the O-acetyltransferase-overproducing strain S. typhimurium NM2009 was applied to the detection of genotoxic activity in atmospheric particles in urban areas using a relatively small sample load. The results showed that the test system was able to detect slight increases in induced genotoxicity in atmospheric particles and that genotoxicity was detected mainly in the fine fraction but also partially in the coarse fraction. The present sensitive microplate test system has potential for application to the screening of various other environmental samples.
Źródło:: Acta Biochimica Polonica; 2003, 50, 1; 291-296
0001-527X
Pojawia się w:: Acta Biochimica Polonica
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 2.

Tytuł:: Genotoksyczność wody do picia w wybranych wodociągach
Genotoxicity of drinking water from some supply systems in Poland
Autorzy:: Podsiadły, T.
Powiązania:: https://bibliotekanauki.pl/articles/237033.pdf
Data publikacji:: 1999
Wydawca:: Polskie Zrzeszenie Inżynierów i Techników Sanitarnych
Tematy:: genotoksyczność wody
woda do picia
wodociągi
test UMU
Opis:: The ever increasing degradation of water sources, as well as the concomitant need of applying chemical disinfectants, has directed the attention of scientists and engineers to the problem of longterm exposure of human organisms to water pollutants with health hazard potential. Considering the specific physico-chemical properties of water, epidemiological studies or long-term experiments on animals are useless. For this reason, our knowledge of the potential mutagenicity of organic water pollutants is based primarily on-bacterial screening tests, such as the UMU test or the Ames test. The need of unifying the investi-gations into the mutagenicity of water gave a spur to DIN and ISO to attempt standardization of the two screening tests mentioned above. For the purpose of the present study, use was made of the Tube UMU test (which resembles the UMU microtest proposed by ISO) to evaluate the genotoxicity of water. The samples under test came from waterworks of choice (which use different treatment methods and different types of water intake), from the water-pipe network, and from oligocenic wells. The present study substantiates the utility of the UMU test in evaluating routinely the genotoxicity of drinking water. Significant genotoxicity levels were detected in the majority of disinfected water samples, and they were found to vary according to the type of intake. More advanced treatment trains (for example those involving carbon beds) bring about a substantial abatement of mutagenicity in drinking water. The genotoxicity ot the disinfected water samples should be attributed to a group of non-volatile pollutants.
Źródło:: Ochrona Środowiska; 1999, 3; 45-48
1230-6169
Pojawia się w:: Ochrona Środowiska
Dostawca treści:: Biblioteka Nauki

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