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Tytuł:
Delusional Misidentification Syndrome: dissociation between recognition and identification processes
Autorzy:
Leis, Kamil
Mazur, Ewelina
Racinowski, Mariusz
Jamrożek, Tomasz
Gołębiewski, Jakub
Gałązka, Przemysław
Pąchalska, Maria
Powiązania:
https://bibliotekanauki.pl/articles/2106025.pdf
Data publikacji:
2019-12-18
Wydawca:
Fundacja Edukacji Medycznej, Promocji Zdrowia, Sztuki i Kultury Ars Medica
Tematy:
intermetamorphosis syndrome
Fregoli syndrome
Capgras syndrome
delusional misidentification syndromes
schizophrenia
Opis:
Delusional misidentification syndrome (DMS) is an umbrella term for syndromes of intermetamorphosis, Fregoli, and Capgras. DMS) is thought to be related to dissociation between recognition and identification processes. DMS was described for the first time in 1932 as a variant of the Capgras syndrome and is currently on the DSM-V list of diseases as an independent disease entity. Patients affected by DMS believed that people around them, most often family, have changed physically (appearance) and mentally (character). Other symptoms include confabulation, derealization or depersonalization. In patients, aggressive behavior is often observed, aimed at alleged doppelgangers resulting from the sense of being cheated and manipulated. With the intermetamorphosis syndrome, for example, schizophrenia, depression, bipolar disorder or other misidentification syndromes (Fregoli's, Capgras) may coexist. There is also a reverse intermetamorphosis, where the object of the changed appearance or character becomes the patient himself. One of its forms may be lycanthropy. The etiology of the intermetamorphosis has not been fully understood, one of the reasons may be brain damage and changes in the parietal and/or temporal lobes of the right hemisphere. It may then damage long neuronal connections to the frontal areas of the brain, disturbances of working memory (WM) accountable for the keep and online management of data, so that it is available for further processing, and the patient's will be uncritical. The basic method of diagnosis of this delusion is a medical interview with the patient. Other diagnostic methods include computed tomography, magnetic resonance imaging, EEG and ERPs. Experimental methods include searching for the neuromarker of DMS. Currently, there are no treatment guidelines of this delusional disorder, and pharmacotherapy experimental, but the drugs from the group of neuroleptics and lithium seem effective. Some hope for the treatment is created by neurotherapy, but it is also experimental.
Źródło:
Acta Neuropsychologica; 2019, 17(4); 456-467
1730-7503
2084-4298
Pojawia się w:
Acta Neuropsychologica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Sjögrens syndrom – the review of the latest diagnostic guidelines essential for otolaryngologists
Autorzy:
Kruk, Karolina
Rzepakowska, Anna
Osuch-Wójcikiewicz, Ewa
Niemczyk, Kazimierz
Powiązania:
https://bibliotekanauki.pl/articles/1399442.pdf
Data publikacji:
2019
Wydawca:
Index Copernicus International
Tematy:
autoimmune sialadenitis
dry mouth
dryness syndrome
sicca syndrome
Sjögren syndrome
Opis:
Sjogren’s syndrome (SS) is a complex connective tissue disease with autoimmune background and high clinical, radiological and molecular heterogeneity. SS is typically manifested by sicca syndrome, characterized by dry eyes and dry mouth due to autoimmune-induced inflammation of the lacrimal and salivary glands. Complications of sicca syndrome are dental caries, oral candidiasis, dysosmia, dysgeusia, difficulties in swallowing and chewing. SS may coexist with other diseases of rheumatoid and autoimmune etiology. SS is linked to an 16-fold increased risk of non-Hodgkin lymphoma. Early diagnosis results in appropriate treatment and may slow down the course of the disease and limit extraglandular involvement. Due to diverse clinical phenotypes and symptomatology, establishing of the diagnosis is often difficult. In 2016 the AmericanEuropean Consensus Group (AECG) and European League Against Rheumatism (EULAR) proposed a classification system that defines SS as a systemic disease. Diagnostic tools in establishing SS diagnosis are serological tests, ultrasonography, Schirmer’s test, unstimulated whole saliva flow rate and Ocular Staining Score. The complete curing of SS is still not possible. As a complex multisystem disease, SS requires multidisciplinary cooperation and individual diagnostic and therapeutic approaches in patients. Therapy is focused on the treatment of symptoms and prophylaxis of complications. The laryngological treatment of oral cavity symptoms in SS include supervision of proper oral hygiene habits and adequate fluids supplementation. The EULAR Sjögren’s syndrome disease activity index (ESSDAI) and Clinical Oral Dryness Score(CODS) are used to monitor disease progression and treatment effectiveness.
Źródło:
Polski Przegląd Otorynolaryngologiczny; 2019, 8, 2; 1-6
2084-5308
2300-7338
Pojawia się w:
Polski Przegląd Otorynolaryngologiczny
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Sjögrens syndrome - diagnosis and contemporary therapeutic possibilities
Autorzy:
Cwalina, Oliwia
Pandey, Ada
Prokop, Dominika
Czarnacka, Kinga
Gawlak, Małgorzata
Kuźlik, Bartosz
Guzek, Katarzyna
Alsoubie, Ismael
Chmura-Hołyst, Alicja
Roszkowska, Anna
Pawlicka, Ilona
Piskorz, Agnieszka
Kozak, Maciej
Powiązania:
https://bibliotekanauki.pl/articles/22792621.pdf
Data publikacji:
2023-06-30
Wydawca:
Medical Education
Tematy:
Sjögren's syndrome
dry eye syndrome
therapeutic options
Opis:
Dry eye syndrome is a group of medical conditions that can be caused by many factors, as a result of which there is an abnormality in moisturizing of the eye surface by a tear film. One of the causes of this disorder is Sjögren’s syndrome, which is an autoimmune disease in which the body produces antibodies against its own proteins. The glands of external secretion, mainly lacrimal and salivary glands are damaged as a result of inflammation. Associated with this side effects, affect negatively and reduce the quality of life, which is why in the following article we present the available therapeutic options for patients suffering from ophthalmological manifestations of Sjögren’s syndrome.
Źródło:
OphthaTherapy; 2023, 10, 2; 110-115
2353-7175
2543-9987
Pojawia się w:
OphthaTherapy
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Measuring the value of scientific achievements
Autorzy:
Drozdowicz, Zbigniew
Powiązania:
https://bibliotekanauki.pl/articles/704077.pdf
Data publikacji:
2019
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
bibliometrics
expert syndrome
point syndrome
impact factors
Opis:
In these considerations, I undertake a polemic with thinking based on the assumption that the value of scientific achievements can be measured with almost mathematical accuracy and give fully reliable point indicators for them. It is not only part of those who introduce the current reform of higher education and science in Poland, but also experts who support them, as well as some representatives of science and natural sciences. This thinking was called point syndrome and expert syndrome. Although it was diagnosed as a manifestation of academic disease a few years ago, it still not only finds its supporters, but also translates into activities, which in some scholars cause astonishment, in others indignation, and still strong opposition in others.
Źródło:
Nauka; 2019, 2
1231-8515
Pojawia się w:
Nauka
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Assessment of surgical treatment of Eagle’s syndrome
Autorzy:
Czajka, Marcin
Szuta, Mariusz
Zapała, Jan
Janecka, Iga
Powiązania:
https://bibliotekanauki.pl/articles/1397804.pdf
Data publikacji:
2019
Wydawca:
Index Copernicus International
Tematy:
Eagle’s syndrome
odynophagia
stylocarotid syndrome
styloid process
Opis:
Introduction: The aim of the study was to assess the effectiveness of surgical treatment of patients with Eagle’s syndrome, taking into account both early and late results. Material and methods: The study group consisted of 15 patients who underwent resection of the styloid process due to Eagle syndrome in the period of 2005–2017. During the follow-up visit, the patients were asked to fill in a post-operative questionnaire that compared the pre-operative symptoms and their severity with the patients’ current health condition. The VAS pain scale was used to assess each symptom, and the Laitinen scale was used to assess the quality of life. Data from patients’ medical records were also included. The results of the surveys were subjected to statistical analysis. Results: The study showed that in 11 out of 15 cases there was a significant improvement in the level of pain (70.5% on average) and an improvement in quality of life (on average 65%) comparing to the pre-operative condition. The Wilcoxon test for binding pairs, the Mann-Whitney test, the Kruskal-Wallis test and the Spearman correlation coefficient were used in the statistical analysis. There were statistically significant correlations between the recorded improvement rate and the length of the resected styloid process and its setting. Discussion: The study proved that resection of prolonged styloid process from extraoral approach in most cases is an effective method of treatment of Eagle syndrome, that carries low risk of complications.
Źródło:
Polish Journal of Otolaryngology; 2019, 73, 5; 18-24
0030-6657
2300-8423
Pojawia się w:
Polish Journal of Otolaryngology
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Triple negative breast cancer with ACTH-dependent Cushings syndrome - case report
Autorzy:
Hodorowicz-Zaniewska, Diana
Brzuszkiewicz, Karolina
Szpor, Joanna
Powiązania:
https://bibliotekanauki.pl/articles/1392214.pdf
Data publikacji:
2019
Wydawca:
Index Copernicus International
Tematy:
breast cancer
paraneoplastic syndrome
ACTH
adrenocorticotropin
Cushing’s syndrome
Opis:
Introduction: Endocrine and metabolic paraneoplastic syndromes in the course of malignant tumors result from ectopic production of hormones or hormone precursors in tumor cells. Production of hormones by endocrine tumors is relatively frequent, while such production by adenocarcinoma cells is definitely rare. The study presents a case of triple-negative invasive breast cancer, with the ectopic secretion of ACTH (adrenocorticotropic hormone), which provokes serious metabolic disorders. Materials and methods: The patient was admitted to hospital with symptoms of Cushing`s syndrome. Diagnostic tests revealed that the cause of metabolic disorders was breast cancer. After proper preparation, the patient was qualified for surgery. Results: After the mastectomy, the patient’s metabolism stabilized. The patient underwent adjuvant chemotherapy and radiotherapy. Four months after the last cycle of systemic treatment, cancer dissemination was found. The patient was treated with second-line chemotherapy, however, control CT revealed progression. The patient died 20 months after surgery and two months after the last cycle of chemotherapy. Conclusions: The case reported in this study – triple-negative invasive breast cancer, responsible for ectopic production of ACTH and causing Cushing’s syndrome – is a rare phenomenon. Treatment of patients with breast cancer showing hormonal activity should not differ from general rules applied for breast cancer. However, due to accompanying metabolic disturbances, the patients need individualized oncological approach, precise diagnostic tests, and adequate preoperative preparation.
Źródło:
Polish Journal of Surgery; 2019, 91, 2; 45-47
0032-373X
2299-2847
Pojawia się w:
Polish Journal of Surgery
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Comparison of the incidence rates of coincident symptoms in a group of patients with Vertigo
Autorzy:
Šichnárek, Jakub
Vyskotová, Jana
Macháčková, Kateřina
Mrázková, Eva
Powiązania:
https://bibliotekanauki.pl/articles/1398471.pdf
Data publikacji:
2017
Wydawca:
Index Copernicus International
Tematy:
vertigo
vestibular disorders
central vestibular syndrome
peripheral vestibular syndrome
Opis:
ÚVOD: Závrať je druhým nejčastějším příznakem. kvůli kterému pacienti musí vyhledat lékaře. Efektivní léčba závrativých stavů vyžaduje spolupráci mnoha lékařských odvětní. CÍL: Cílem bylo analyzovat údaje z databáze pacientů s vertigem vyšetřených v Centru pro poruchy sluchu a rovnováhy v Ostravě – Porubě, zjistit, zda a v jakých faktorech se od sebe odlišují soubory pacientů s diagnostikovaným centrálním a periferním vestibulárním syndromem. METODIKA: výzkum byl proveden formou retrospektivní studie, která probíhala od října 2012 do února 2013. Data byla sbírána z dokumentace všech pacientů, kteří byli vyšetřeni otoneurologem na základě potíží s vertigem. VÝSLEDKY: Statisticky významný rozdíl byl nalezen mezi soubory s centrálním a periferním vertigem ve výskytu hypertenze, poruchy sluchu, zánětů středního ucha, mírné obezity a výsledky stabilometrického vyšetření. ZÁVĚR: Rozdíl mezi soubory s periferním a centrálním souborem jsou zmíněny výše. Mezi ostatními hledanými příznaky nebyl nalezen rozdíl. Výsledky potvrzují nutnost multioborového přístupu k pacientům s vertigem.
Źródło:
Polish Journal of Otolaryngology; 2017, 71, 1; 34-39
0030-6657
2300-8423
Pojawia się w:
Polish Journal of Otolaryngology
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Porównanie częstości występowania objawów współistniejących w grupie pacjentów z zawrotami głowy
Autorzy:
Šichnárek, Jakub
Vyskotová, Jana
Macháčková, Kateřina
Mrázková, Eva
Powiązania:
https://bibliotekanauki.pl/articles/1398477.pdf
Data publikacji:
2017
Wydawca:
Index Copernicus International
Tematy:
vertigo
vestibular disorders
central vestibular syndrome
peripheral vestibular syndrome.
Opis:
BACKGROUND: Dizziness is the second most frequent symptom that make patients seek specialized examination. The effective solution of dizzy conditions requires treatment in cooperation with different branches of medicine. OBJECTIVE: To analyze data from the database of patients with vertigo examined in the Hearing and Balance Disorder Centre in Ostrava, to find out whether, and in what factors, the sets of patients with diagnosed central and peripheral vestibular syndrom differ from each other. METHODS: Retrospective study that was carried out from October 2012 to February 2013. The data was gathered from documentation of all vertiginous patients who were examined by an otoneurologist. RESULTS: The statistically significant difference between the two sets was found in: occurrence of hypertension and mild obesity, impaired hearing and otitis media, stabilometric testing CONCLUSIONS: There was a statistically significant difference between the sets with the central and peripheral vestibular syndrome in the frequency of occurrence of hypertension, impaired hearing, otitis media, in mild obesity categorization and in balance disorders. There was not any statistically significant difference found in the other observed factors. The results confirm the need of a multidisciplinary approach to patients with vertigo.
Źródło:
Polish Journal of Otolaryngology; 2017, 71, 1; 34-39
0030-6657
2300-8423
Pojawia się w:
Polish Journal of Otolaryngology
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Ascites Index – an attempt to objectify the assessment of ascites
Ascites Index – próba obiektywizacji oceny nasilenia wodobrzusza
Autorzy:
Szkodziak, Piotr
Czuczwar, Piotr
Pyra, Krzysztof
Szkodziak, Filip
Paszkowski, Tomasz
Rio Tinto, Hugo
Woźniak, Sławomir
Powiązania:
https://bibliotekanauki.pl/articles/1033124.pdf
Data publikacji:
2018
Wydawca:
Medical Communications
Tematy:
ovarian hyperstimulation syndrome
Opis:
Introduction: Ascites is observed in cancer patients as well as in other non-neoplastic processes. In some patients, it may cause severe symptoms that can become directly life-threatening. The assessment of the degree of ascites seems useful in the determination of treatment effects as well as in the monitoring of fluid accumulation and early planning of decompression procedures. Aim: Determination of the clinical usefulness of a quantitative method of determining the degree of ascites, so-called Ascites Index. Material and methods: The Ascites Index is an ultrasonographic way of assessing the grade of ascites. The examination result is an index which is analogous to the amniotic fluid index determined in pregnant patients. The Ascites Index was determined in patients with ascites in the course of stage III–IV ovarian carcinoma (7 patients) and ovarian hyperstimulation syndrome (12 patients). Results: The patients with ovarian hyperstimulation syndrome required decompressive paracentesis at the median Ascites Index above 290 mm (range: 216–386 mm). In the patients with ovarian carcinoma, the median value of the Ascites Index at which paracentesis was required was 310 mm (range: 273–389 mm). To avoid complications associated with excessive protein loss, 2000 mL of fluid was evacuated at a single occasion. Following the procedure, the median value of the Ascites Index was 129 mm (range: 121–145 mm) in the patients with ovarian hyperstimulation syndrome and 146 cm (119–220 mm) in cancer patients. Conclusions: The proposed index is simple and rapid to determine. It makes evaluation of the degree of ascites considerably easier. Moreover, it only minimally burdens patients and enables assessment of the effect of decompression or treatment. It seems that this method might be useful also in the assessment of ascites caused by other factors, but this requires further clinical studies.
Wstęp: Wodobrzusze jest objawem występującym u chorych z chorobą nowotworową, obserwowanym także w procesach nienowotworowych. W nielicznej grupie pacjentów wywołuje silne dolegliwości, które mogą bezpośrednio zagrażać życiu. Przydatność oceny wielkości wodobrzusza wydaje się uzasadniona w określaniu efektów leczenia, a także w monitorowaniu narastania płynu i wcześniejszym planowaniu procedur odbarczających. Cel: Wykazanie klinicznej przydatności metody ilościowego oznaczania wielkości wodobrzusza – indeksu wodobrzusza (ascites index). Materiał i metody: Indeks wodobrzuszajest ultrasonograficznym sposobem oceny wielkości wodobrzusza. Badanie wykonuje się, tworząc indeks analogiczny do indeksu płynu owodniowego u ciężarnej. Ascites index oznaczano u pacjentek z wodobrzuszem w przebiegu raka jajnika w stopniu III–IV (7 pacjentek) oraz zespołu hiperstymulacji jajników (12 pacjentek). Wyniki: Przy wartości mediany indeksu wodobrzuszapowyżej 290 mm (zakres: 216–386 mm) pacjentki z zespołem hiperstymulacji jajników wymagały wykonania odbarczającej punkcji jamy otrzewnej. U pacjentek z rakiem jajnika wartość mediany indeksu wodobrzuszawymagająca paracentezy wyniosła 310 mm (zakres: 273–389 mm). Aby uniknąć komplikacji związanych z nadmierną utratą białka, jednorazowo upuszczono 2000 ml płynu. Po paracentezie u pacjentek leczonych z powodu zespołu hiperstymulacji jajników wartość mediany ascites indexwyniosła 129 mm (zakres: 121–145 mm), natomiast u kobiet z rakiem jajnika wartość tę oszacowano na 146 cm (119–220 mm). Wnioski: Zaproponowany indeks jest prosty i szybki do wykonania, znacznie ułatwia oszacowanie wielkości wodobrzusza, minimalnie obciąża osoby badane, a także umożliwia ocenę efektu odbarczenia lub leczenia. Wydaje się, że metoda ta będzie przydatna również w ocenie wielkości wodobrzusza spowodowanego innymi czynnikami niż analizowane, wymaga to jednak dalszych badań klinicznych.
Źródło:
Journal of Ultrasonography; 2018, 18, 73; 140-147
2451-070X
Pojawia się w:
Journal of Ultrasonography
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Skutki przemocy – zespół barona Münchhausena
Effects of violence – Munchhausen syndrome
Autorzy:
Żukowska-Nawrot, Karina
Powiązania:
https://bibliotekanauki.pl/articles/501377.pdf
Data publikacji:
2012
Wydawca:
Instytut Studiów Międzynarodowych i Edukacji Humanum
Tematy:
violence
Munchhausen syndrome
Opis:
Humanistic psychology assumes that a child is by nature good and noble, and what he will become in the future depends on the kind of environment where the processes of upbringing and socialisation have taken place. Violence is beyond any doubt a social phenomenon which does not have any moral, territorial, or religious borders. Experiencing violence in childhood often determines undertaking destructive behaviours by an individual.
Źródło:
Społeczeństwo i Edukacja. Międzynarodowe Studia Humanistyczne; 2012, 2(10); 215-218
1898-0171
Pojawia się w:
Społeczeństwo i Edukacja. Międzynarodowe Studia Humanistyczne
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Differential diagnosis between fibromyalgia syndrome and myofascial pain syndrome
Autorzy:
Chochowska, M.
Szostak, L.
Marcinkowski, J.T.
Jutrzenka-Jesion, J.
Powiązania:
https://bibliotekanauki.pl/articles/3306.pdf
Data publikacji:
2015
Wydawca:
Instytut Medycyny Wsi
Tematy:
diagnosis
fibromyalgia syndrome
myofascial pain syndrome
trigger mechanism
human disease
Opis:
Introduction. Fibromyalgia syndrome (FMS) and myofascial pain syndrome (MFPS) can be ranked among disease entities being difficult to diagnose clinically, manifesting themselves mainly through pain in specific hypersensitivity points. Aim. To present the current state of medical knowledge about pain spots appearing on hypersensitive points of soft tissue in the context of selected disease entities. Summary of the knowledge. MFPS is defined as sensory, motor and autonomic complaints, caused by the occurrence of trigger points (TrP). Yet the FMS is stated during the anamnesis on the basis of generalized pain, and pressure achiness of at least 11 out of 18 tender points (TP) of precisely determined location. Patients with FMS report numerous additional complaints – apart from the above mentioned ones; these are however highly non-specific and are not confirmed during routine medical check-ups. There are also no laboratory tests that can confirm presence of TrP being characteristic to MFPS and differentiating it from other muscles’ disease entities. Such points are identified only with the use of palpation. Unfortunately while examining a patient this way TrP – being symptoms of MFPS – can be quite easily confused with TP – being symptoms of FMS. Patients with MFPS which is developing in consequence of long-lasting global disorder of muscle tension balance and sensitivity of nociceptors as a result of chronically remaining pain, frequently suffer from achiness fulfilling the criteria of generalized pain. Moreover – in effect of static overload of soft tissues (especially of tonic muscles) – there occur hypersensitive palpable areas (points). Stimulating them cause lively reaction of the patient. Described symptoms can suggest a suspicion of FMS – the more so that making a diagnosis of MFPS does not exclude its coexistence. Having this in mind, there is a pretty large group of authors who raise a supposition that the differential diagnosis between TrP and TP should be observed in the quantitative rather than in the qualitative categories, despite the still binding definition and nomenclature. Recapitulation. Looking at the MFPS and at the FMS from the perspective of evolution of knowledge about them and from the point of view of period when scientific researches were conducted and their results published, it must be stated that during last years a considerable progress has been obtained in scope of better understanding of pathogenesis and pathophysiology of pain in specified points of soft tissue hypersensitivity, and the parallel clinical studies – confirming the hypotheses that were made – clearly increased the diagnostic and therapeutic capabilities of clinical practice.
Źródło:
Journal of Pre-Clinical and Clinical Research; 2015, 09, 1
1898-2395
Pojawia się w:
Journal of Pre-Clinical and Clinical Research
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Paraneoplastic syndromes in daily clinical practice
Autorzy:
Wojtowicz, M.
Rekas-Wojcik, A.
Lipa, A.
Prystupa, A.
Dzida, G.
Powiązania:
https://bibliotekanauki.pl/articles/3530.pdf
Data publikacji:
2014
Wydawca:
Instytut Medycyny Wsi
Tematy:
human disease
paraneoplastic syndrome
disease syndrome
clinical practice
cancer
patient
Opis:
Paraneoplastic syndromes consist of disorders that accompany benign and malignant tumours, but are not directly related to mass effects or invasion by the primary tumour or its metastases. The pathophysiology of mostly paraneoplastic syndromes is not well known. The usual mechanism of their development is the aberrant production of substances (protein hormones, hormone precursors or hormone-like substances) by tumour tissue or autoimmune disorder. The neurological paraneoplastic syndromes are autoimmune disorders that can affect almost any part of the nervous system. The endocrine paraneoplastic syndromes are often certain clinical syndromes like paraneoplastic hypercalcaemia or the aberrant production of hormones by cancers. Many haematologic conditions, including anaemia, leucocytosis, thrombocytopenia or thrombocytosis, coagulapathy have been reported in association with cancer. Also paraneoplastic rheumatic syndromes have been reported in association of cancer. Skin can be involved in cancer in different ways: by metastases, as a part of a genetic disorder with a cutaneous component in which there is an inherited predisposition to the later development of malignancy, as a part of an acquired syndrome due to the toxicity of a carcinogen that induces malignant change and accompanying skin changes, as a consequence of immunosuppression, or by the development of specific lesions that occur as a paraneoplastic syndromes The most frequently diagnosed dermatologic conditions include acrokeratosis paraneoplastica, Sweet’s syndrome and paraneoplastic pemphigus. The purpose of this article is to describe the most popular in internal clinical practice neurologic, endocrine, haematologic, rheumatologic and dermatologic paraneoplastic syndromes associated with cancer.
Źródło:
Journal of Pre-Clinical and Clinical Research; 2014, 08, 2
1898-2395
Pojawia się w:
Journal of Pre-Clinical and Clinical Research
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Iron in medicine and treatment
Żelazo w medycynie i lecznictwie
Autorzy:
Luchowska-Kocot, D.
Powiązania:
https://bibliotekanauki.pl/articles/13550.pdf
Data publikacji:
2014
Wydawca:
Uniwersytet Warmińsko-Mazurski w Olsztynie / Polskie Towarzystwo Magnezologiczne im. Prof. Juliana Aleksandrowicza
Tematy:
iron
medicine
treatment
iron deficiency
anaemia
restless legs syndrome
Willis-Ekbom disease zob.restless legs syndrome
Wittmaack-Ekbom syndrome zob.restless legs syndrome
pregnancy
Opis:
Being a component of many proteins and enzymes, iron is an essential microelement for humans. However, this element can also be toxic when present in excess because of its ability to generate reactive oxygen species. This dual nature imposes a strict regulation mechanism of the iron concentration in the body. In humans, systemic iron homeostasis is mainly regulated on the level of intestinal absorption. A patient diagnosed with excess iron in the body should be treated safely and effectively. And the therapy should be consistent with the treatment of concurrent diseases. On the other hand, iron deficiency is one of the most common disorders affecting humans. Iron-deficiency anaemia continues to represent a major public health problem worldwide, being prevalent among pregnant women, where it represents an important risk factor for maternal and infant health. A problem detecetd relatively recently and therefore not fully clarified yet is the iron therapy in patients with restless legs syndrome (RLS). RLS is a common neurological condition defined clinically as the urge to move the legs. Reduced brain iron is strongly associated with restless legs syndrome. RLS can also be a consequence of iron deficiency in the body. This review will focus on iron as an element whose abnormal metabolism or deficiency in the body can lead to diseases e.g. anaemia, restless legs syndrome and iron overload. Here we will describe methods of therapy, paying particular attention to the types and dosages of medications.
Żelazo jest podstawowym mikroelementem organizmu ludzkiego, stanowi bowiem istotny element wielu białek i enzymów. Jednak pierwiastek ten może wykazywać działanie toksyczne, gdy występuje w nadmiarze, ze względu na jego zdolność do generowania reaktywnych form tlenu. Ten podwójny charakter żelaza narzuca ścisłą regulację stężenia żelaza w organizmie. U ludzi homeostaza ustrojowa żelaza jest głównie regulowana na poziomie wchłaniania jelitowego. Pacjent, u którego zdiagnozowano nadmiar żelaza w organizmie, powinien być poddany bezpiecznemu i skutecznemu leczeniu, które jest zgodne z terapią współistniejących schorzeń. Niedobór żelaza jest jednym z najczęstszych zaburzeń dotykających ludzi. Niedokrwistość spowodowana niedoborem żelaza nadal stanowi istotny problem zdrowia publicznego na całym świecie. Szczególnie dotyczy kobiet w ciąży, stanowiąc istotny czynnik ryzyka dla zdrowia matki i dziecka. Stosunkowo nowym i nie do końca wyjaśnionym zagadnieniem jest terapia żelazem chorych na zespół niespokojnych nóg (RLS). Jest to stan neurologiczny klinicznie określany jako przymus poruszania nogami. Z zespołem niespokojnych nóg związana jest ściśle redukcja żelaza w mózgu. RLS może być również konsekwencją niedoboru żelaza w organizmie. W pracy omówiono nieprawidłowy metabolizm żelaza lub jego brak w organizmie, co może prowadzić do ww. jednostek chorobowych. Opisano również metody terapii, zwracając szczególną uwagę na rodzaj i wielkość dawki proponowanych leków.
Źródło:
Journal of Elementology; 2014, 19, 3
1644-2296
Pojawia się w:
Journal of Elementology
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Kounis syndrome associated with Moxifloxacin infusion in a patient with COVID-19 pneumonia: a case report
Autorzy:
Tverdokhlib, Ivan
Skakun, Oleksiy
Fedorov, Sergiy
Verbovska, Olga
Kozlova, Irena
Martyniv, Ilona
Powiązania:
https://bibliotekanauki.pl/articles/29432072.pdf
Data publikacji:
2021-06
Wydawca:
Towarzystwo Pomocy Doraźnej
Tematy:
Kounis syndrome
acute coronary syndrome
COVID-19
coronary vasospasm
case report
Opis:
Kounis syndrome (KS) is an acute coronary syndrome developing as a consequence of an anaphylactic or allergic reaction. Multiple mediators (especially histamine) released by mast cells, platelets, and some immune cells may lead to coronary vasospasm or thrombosis and cause an acute coronary syndrome. A clinical case of the KS in a hospitalized patient being treated for the COVID-19-associated pneumonia is presented. A 62-year-old woman was treated for COVID-19-associated pneumonia. In 15 min after the beginning of the Moxifloxacin infusion, the patient complained of severe headache, crushing chest pain, abdominal pain, severe general weakness, shortness of breath. Hypotension and decrease in SpO2 developed. Immediately performed ECG showed the ST-segment elevation in leads I and aVL. There were reciprocal changes in leads III, aVF, V3-V6. Troponin I was slightly elevated. Coronary angiography showed no hemodynamically significant coronary artery lesions. The KS type 1 was diagnosed. Repeated ECG in 2 hours showed isoelectric ST segments in all leads. It may be difficult to diagnose KS. Clinical signs of an allergic or anaphylactic reaction should raise the suspicion of KS. Moxifloxacin as well as other fluoroquinolones may be associated with the development of KS. We suggest a possible association of COVID-19 with KS. However, this issue requires further observation.
Źródło:
Critical Care Innovations; 2021, 4, 2; 32-37
2545-2533
Pojawia się w:
Critical Care Innovations
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Gall-Stone Ileus – Own Patients And Literature Review
Autorzy:
Kozieł, Sławomir
Papaj, Piotr
Dobija-Kubica, Katarzyna
Śleziński, Przemysław
Wróbel, Józef
Powiązania:
https://bibliotekanauki.pl/articles/1395609.pdf
Data publikacji:
2015-05-01
Wydawca:
Index Copernicus International
Tematy:
gall-stone
gall-stone ileus
Bernard’s syndrome
Bouveret syndrome
cholelitchiasis
Opis:
Cholelithiasis is diagnosed in 10% of the population of the USA and Western Europe. A rare but serious complication of cholelithiasis is the obstruction of the digestive tract caused by a gall-stone (Bernard syndrome). It can add up to 1-4% of the mechanical obstructions of a small intestine among the general population but it can result in nonstriangulational mechanical obstructions of a small intestine in 25% cases among the patients over the age of 65. 5 patients have undergone an operation due to a small intestine gall-stone ileus in years 2011-2013 (within 27 months) in the General Surgery Ward of the Beskid Oncology Center - Municipal Hospital. In 4 patients simple enterotomy with a gall-stone extraction was performed. In the fifth patient enterolitotomy was conducted together with cholecystectomy and fistulotomy.
Źródło:
Polish Journal of Surgery; 2015, 87, 5; 260-267
0032-373X
2299-2847
Pojawia się w:
Polish Journal of Surgery
Dostawca treści:
Biblioteka Nauki
Artykuł

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