Temat: stress ulcer - Katalog OPAC zbiorów

Skocz do pozycji: 1.

Tytuł:: Histamine in stress ulcer prophylaxis in rats
Autorzy:: Warzecha, Z.
Dembinski, A.
Brzozowski, T.
Ceranowicz, P.
Dembinski, M.
Stachura, J.
Konturek, S.J.
Powiązania:: https://bibliotekanauki.pl/articles/69120.pdf
Data publikacji:: 2001
Wydawca:: Polskie Towarzystwo Fizjologiczne
Tematy:: gastric ulcer
histamine
gastric blood flow
interleukin 1beta
DNA synthesis
gastric acid secretion
prophylaxis
gastroprotection
rat
stress ulcer
gastrin
Źródło:: Journal of Physiology and Pharmacology; 2001, 52, 3
0867-5910
Pojawia się w:: Journal of Physiology and Pharmacology
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 2.

Tytuł:: Ameliorative Effect of Ethanolic Extract of Laportea aestuans (L.) Chew on Gastric Oxidative Damage in Aspirin - Induced Gastric Ulcer in Male Rats
Autorzy:: Onadeko, Akinwande
Akinola, Olusegun
Powiązania:: https://bibliotekanauki.pl/articles/1839808.pdf
Data publikacji:: 2021
Wydawca:: Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
Tematy:: Gastric Ulcer
Oxidative Stress
Cimetedine
Phytochemicals
Aspirin
Laportea aestuans
Opis:: Non-steroidal anti-inflammatory drugs (NSAIDs) are connected with the generation of free radicals and one of its adverse effects is gastric ulceration. Ulceration was induced orally using aspirin. Twenty-four male Wistar rats were used for this study (120-150g). Rats were divided into 6 groups with each group containing 4 rats. Rats were pre-treated orally with cimetidine, a reference drug. Group 1 rats orally received 1% gum acacia solution as the control group, Group 2 rats orally administered 25 mg/kg aspirin and served as the ulcerated, untreated group, rats in groups 3 and 4 were pre-treated orally with 200 mg/kg and 400 mg/kg respectively for 3 days while rats in groups 5 and 6 were pre-treated orally with 50 mg/kg cimetidine and 50 mg/kg catechin respectively for 3 days. The result of this study shows that the ulcerated, untreated rats showed increased concentrations of gastric volume with a concomitant decrease in protein concentration compared to the control group, cimetidine and catechin reversed these observations. Activities of glutathione, catalase were decreased in the ulcerated, untreated group but pre-treatment with different doses, cimetidine and catechin reversed these observations. In conclusion, the ethanoic extract of L. aestuans can be said to be used as an anti-ulcerogenic agent against aspirin-induced gastric ulcer which is due to the presence of phytochemicals in the plant.
Źródło:: World News of Natural Sciences; 2021, 39; 86-94
2543-5426
Pojawia się w:: World News of Natural Sciences
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 3.

Tytuł:: Interval hypoxic training in complex treatment of Helicobacter pylori-associated peptic ulcer disease
Autorzy:: Semen, Khrysyna
Yelisyeyeva, Olha
Kaminskyy, Danylo
Cherkas, Andriy
Zarkovic, Kamelija
Lutsyk, O
Cipak, Ana
Jaganjac, Morana
Zarkovic, Neven
Powiązania:: https://bibliotekanauki.pl/articles/1040404.pdf
Data publikacji:: 2010
Wydawca:: Polskie Towarzystwo Biochemiczne
Tematy:: heart rate variability
peptic ulcer
oxidative homeostasis
interval hypoxic training
oxidative stress
Opis:: This study was aimed to demonstrate the efficacy of interval hypoxic training (IHT) in complex treatment of Helicobacter pylori-associated duodenal peptic ulcer disease (DPUD) by parameters of aerobic metabolism and indexes of heart rate variability (HRV). Eighty patients with H. pylori-associated DPUD were included into the study, mean age 32±1.8 yrs, duration of the disease up to 10 years (66.3 %). IHT was modulated using Frolov's hypoxicator (TDI-01) for 30 days after standard eradication therapy. Daily hypoxic sessions consisted of three one-minute sessions, one two-minute, and one three-minute sessions separated by one-minute intervals of room-air breathing. Use of IHT resulted in more efficient elimination of clinical symptoms, histological hallmarks of inflammation and signs of oxidative stress in glandulocytes of the gastric mucosa as determined by 4-hydroxynonenal accumulation. Moderate prooxidant activity of IHT was demonstrated by the increased level of TBARS and oxidatively modified products, normalization of hydroperoxides, middle mass molecules and atherogenic beta-lipoproteins with simultaneous increase in catalase activity and mild decline of SOD activity. Therefore, IHT appeared to be accompanied by higher intensity of redox reactions and enhanced regeneratory processes in cells and tissues. Significant increase in HRV was also noted. Such changes were associated with reduction of inflammation signs and modulation of the autonomic homeostasis in DPUD patients. In general, use of IHT in complex treatment of H. pylori in DPUD patients can be recommended to increase resistance to oxidative stress and to modulate autonomic balance and oxidative homeostasis.
Źródło:: Acta Biochimica Polonica; 2010, 57, 2; 199-208
0001-527X
Pojawia się w:: Acta Biochimica Polonica
Dostawca treści:: Biblioteka Nauki

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