Temat: steroid - Katalog OPAC zbiorów

Skocz do pozycji: 1.

Tytuł:: SOCS3 is epigenetically up-regulated in steroid resistant nephrotic children
Autorzy:: Zaorska, Katarzyna
Zawierucha, Piotr
Ostalska-Nowicka, Danuta
Nowicki, Michał
Powiązania:: https://bibliotekanauki.pl/articles/1038853.pdf
Data publikacji:: 2016
Wydawca:: Polskie Towarzystwo Biochemiczne
Tematy:: methylation
nephrotic syndrome
single nucleotide polymorphism
steroid resistance
Opis:: Background. The mechanism of steroid resistance in children with the nephrotic syndrome is yet unknown. About 20% of patients demonstrate steroid unresponsiveness and progress to end stage renal disease. Aberrant SOCS3 and SOCS5 expression in steroid resistant and sensitive patients has previously been demonstrated. Here, we investigate genetic and epigenetic mechanisms of regulation of SOCS3 and SOCS5 transcription in nephrotic children. Methods. 76 patients with the nephrotic syndrome (40 steroid resistant and 36 steroid sensitive) and 33 matched controls were included in this study. We performed genotyping of a total of 34 single nucleotide polymorphisms for SOCS3 and SOCS5 promoters and evaluated their methylation status using MS-PCR and QMSP methods. Results. Steroid resistant patients had a significantly lower methylation of one region of SOCS3 promoter in comparison with steroid sensitive patients and controls (p < 0.0001). However, the relative methylation level in the steroid sensitive patients and controls differed significantly even before the first steroid dose (p = 0.001758). Other SOCS3 and SOCS5 promoter regions displayed no differences in methylation or were fully methylated/unmethylated in all study groups, showing site-specific methylation. The allele and genotype distribution for SOCS3 and SOCS5 markers did not differ statistically between the groups. Conclusions. We demonstrate an epigenetic mechanism of SOCS3 up-regulation in steroid resistant children with the nephrotic syndrome. The assessment of methylation/unmethylation of SOCS3 promoter might be an early marker for steroid responsiveness in NS patients.
Źródło:: Acta Biochimica Polonica; 2016, 63, 1; 131-138
0001-527X
Pojawia się w:: Acta Biochimica Polonica
Dostawca treści:: Biblioteka Nauki

Artykuł

Zmień widok

na półce

Skocz do pozycji: 2.

Tytuł:: Qa-SNARE protein SYP22 negatively regulates brassinosteroid signaling in the dark
Autorzy:: Yao, T.S.
Zhu, X.F.
Jung, J.H.
Xuan, Y.H.
Powiązania:: https://bibliotekanauki.pl/articles/19201.pdf
Data publikacji:: 2015
Wydawca:: Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:: SNARE protein
SYP22 gene
brassinosteroid
steroid hormone
signalling
dark
Arabidopsis
Źródło:: Acta Biologica Cracoviensia. Series Botanica; 2015, 57, 2
0001-5296
Pojawia się w:: Acta Biologica Cracoviensia. Series Botanica
Dostawca treści:: Biblioteka Nauki

Artykuł

Zmień widok

na półce

Skocz do pozycji: 3.

Tytuł:: Time dependent and cell-specific action of polychlorinated biphenyls (PCB 153 and PCB 126) on steroid secretion by porcine theca and granulosa cells in mono- and co-culture
Autorzy:: Wojtowicz, A.K.
Gregoraszczuk, E.L.
Lyche, J.L.
Ropstad, E.
Powiązania:: https://bibliotekanauki.pl/articles/70063.pdf
Data publikacji:: 2000
Wydawca:: Polskie Towarzystwo Fizjologiczne
Tematy:: polychlorinated biphenyl
granulosa cell
cell
toxicity
steroid secretion
porcine theca
steroidogenesis
preovulatory follicle
breast milk
Źródło:: Journal of Physiology and Pharmacology; 2000, 51, 3
0867-5910
Pojawia się w:: Journal of Physiology and Pharmacology
Dostawca treści:: Biblioteka Nauki

Artykuł

Zmień widok

na półce

Skocz do pozycji: 4.

Tytuł:: O-GlcNAcylation, steroid hormone receptors and cancer
O-GlcNAcylacja, receptory dla steroidów i nowotwory
Autorzy:: Wilkosz, Jacek
Różański, Waldemar
Bryś, Magdalena
Forma, Ewa
Powiązania:: https://bibliotekanauki.pl/articles/1032739.pdf
Data publikacji:: 2013
Wydawca:: Łódzkie Towarzystwo Naukowe
Tematy:: o-glcnacylation
steroid hormone receptors
cancer
o-glcnacylacja
receptory dla steroidów
nowotwór
Opis:: The addition of a single residue of O-linked N-acetylglucosamine (O-GlcNAc) to serine or threonine is a post-translational modification (O-GlcNAcylation) of proteins found in the cytoplasm or the nucleus. This dynamic modification is dependent on the environmental glucose concentration. O-GlcNAc modification is catalysed by a glycosyltransferase named O-linked N-acetylglucosaminyltransferase (OGT), and O-GlcNAc residue is removed by the antagonistic enzyme β-N-acetylglucosaminidase (O-GlcNAcase; OGA). Cytosolic O-GlcNAcylation is important for the proper transduction of signalling cascades, whereas nuclear O-GlcNAc is crucial for the transcriptional regulation. O-GlcNAcylation is also important in the regulation of the transcriptional activity of steroid hormone receptors. Both O-GlcNAc transferase and O-GlcNAcase are found in all tissues and have been shown to be essential for development in vertebrates, which underscores their fundamental roles in vital processes as well as in pathological conditions such as neoplastic transformation.
Glikozylacja polegająca na przyłączeniu pojedynczych reszt β-N-acetylo- D-glukozaminy do reszt seryny lub treoniny polipeptydu wiązaniem O-glikozydowym (O-GlcNAc), jest powszechną modyfikacją białek jądrowych i cytoplazmatycznych. Modyfikacja ta pozostaje w ścisłym związku z dostępnością glukozy. β-N-acetyloglukozaminylotransferaza (O-GlcNAc transferaza, OGT) jest enzymem odpowiedzialnym za katalityczne przyłączenie reszt O-GlcNAc, natomiast β-N-acetylo-D-glukozaminidaza (OGA) reszty te odłącza. Proces O-GlcNAcylacji zachodzący w cytozolu jest istotny z punktu widzenia transmisji sygnału komórkowego, natomiast przyłączanie reszt O-GlcNAc na terenie jądra wpływa na proces transkrypcji. Wykazano, że proces O-GlcNAcylacji moduluje regulację aktywności transkrypcyjnej receptorów hormonów steroidowych. Oba enzymy, O-GlcNAc transferaza i β-N-acetylo- D-glukozaminidaza wykrywane są we wszystkich tkankach i jak wykazano, niezbędne są dla prawidłowego rozwoju organizmu, jak również mogą uczestniczyć w procesie transformacji nowotworowej.
Źródło:: Folia Medica Lodziensia; 2013, 40, 1; 133-149
0071-6731
Pojawia się w:: Folia Medica Lodziensia
Dostawca treści:: Biblioteka Nauki

Artykuł

Zmień widok

na półce

Skocz do pozycji: 5.

Tytuł:: Hormony steroidowe, leki przeciwzapalne, pigułki antykoncepcyjne. związki i ludzie : notatki historyczne (część I i II)
Hormones, antiinflammatory drugs, contraceptive pills. compounds and the people : historic notes (part I and II)
Autorzy:: Wicha, Jerzy
Powiązania:: https://bibliotekanauki.pl/articles/1409983.pdf
Data publikacji:: 2021
Wydawca:: Polskie Towarzystwo Chemiczne
Tematy:: notatki historyczne
steroidy
hormony płciowe
kortykosteroidy
pigułki antykoncepcyjne
transformacje steroidowe
synteza totalna
historic notes
steroids
sex hormones
corticosteroids
contraceptive pills
steroid transformations
total synthesis
Opis:: A short historical outlook of steroid hormones isolation, structure elucidation and hormonal drugs development following by a survey of contraceptive therapeutics syntheses and advancements is given. Structural evolution of the first pills, “the pill”, to the presently used oral contraceptives for women is scrutinized. Comments on activities of selected major researchers in the field: Josef Fried, Russell E. Marker, Arthur J. Birch, Carl Djerassi, Georgy G. Pincus, M. C. Chang, John Rock, Igor V. Torgov, Zoltan G. Hajos and Herchel Smith from the personal prospect are presented. Steroid sex hormones, estrogens (female), androgens (male) and gestagens (progesterone, pregnancy hormone) were isolated and identified as chemical entities in 20-tiest and 30-ties of the 20th century. Development of partial synthesis of basic hormones from cholesterol made possible the initial steroid drugs production: Testosterone propionate and 17a-Methyltestosterone (Ciba) as well as Proviron, Progynon, Proluton (Schering AG). In 1940th and 1950th corticosteroids were isolated and recognized as “magic” anti-inflammatory and antiarthritic drugs. Growing demand for antiarthritic drugs in 1950th stimulated search for new corticosteroid analogues and new steroid row materials. Exploration of Mexican plant Dioscorea “cabeza” by Synthex SA provided economical starting material, diosgenin, and opened the new prospects for hormonal drug research and the production. Subsequently, highly active corticosteroid analogues were developed by several pharmaceutical companies and 19-norprogesterone analogues of high gestagenic activity were synthesized - Norethisterone (Synthex) and Norethyndrel (Searle). Complex studies on the application of Norethyndrel as oral contraceptive for women were carried out in the Worcester Foundation for Experimental Biology. In 1959 the first drug “the pill”, which was developed on the grounds of Searls’ Norethyndrel - Enovid was registered by Food and Drug Administration in the USA. Shortly after that Norlutin, based upon Synthex’s Norethisterone, had also been approved for application. Commercial success of “the pill”, Enovid and Norlutin, triggered a broad research aimed at the partial synthesis and application of related progesterone analogues. In the end of 1950th and the beginning of 1960th the total synthesis of estrogens and 19-norsteroids gained practical importance. On these grounds Norgestrel and its active enancjomer Levonorgestrel were developed and commercialized by Wyeth Laboratories Inc. in the USA as the first contraceptive products by total synthesis. Starting from 1970th medicinal applications of corticosteroids gradually diminished, whereas growing attention was given to the development of hormonal contraceptives suitable for general application. Several synthetic modifications of Norethisterone and Levonorgestrel were developed and produced in a large scale. Another class of oral contraceptives stem from the steroid total synthesis developed in the Russell Uclaf laboratories. Structurally these compounds are characterized by 19-norsteroid core and the presence of bulky substituent at the position 11ß, as 4-(N,N-dimethylamino)phenyl- in Mifepristone (RU 486). The synthesis of 19-norpregnane derivatives bearing at the position 11ß various large aromatic or alphatic groups, which currently is receiving a great deal of attention, is considered.
Źródło:: Wiadomości Chemiczne; 2021, 75, 5-6; 677-753
0043-5104
2300-0295
Pojawia się w:: Wiadomości Chemiczne
Dostawca treści:: Biblioteka Nauki

Artykuł

Zmień widok

na półce

Skocz do pozycji: 6.

Tytuł:: Prenatal glucocorticoids can programme postnatal development
Autorzy:: Tomaszewska, E.
Dobrowolski, P.
Powiązania:: https://bibliotekanauki.pl/articles/3123.pdf
Data publikacji:: 2011
Wydawca:: Instytut Medycyny Wsi
Tematy:: prenatal glucocorticoid
glucocorticoid
postnatal development
bone
dexamethasone
steroid hormone
Źródło:: Journal of Pre-Clinical and Clinical Research; 2011, 05, 1
1898-2395
Pojawia się w:: Journal of Pre-Clinical and Clinical Research
Dostawca treści:: Biblioteka Nauki

Artykuł

Zmień widok

na półce

Skocz do pozycji: 7.

Tytuł:: The pattern of steroid secretion by perifused preovulatory rat follicles
Autorzy:: Szoltys, M
Powiązania:: https://bibliotekanauki.pl/articles/70002.pdf
Data publikacji:: 1995
Wydawca:: Polskie Towarzystwo Fizjologiczne
Tematy:: radioimmunoassay
steroid production
progesterone
rat follicle
steroid
endocrinology
steroid analysis
ovulation
androgen
animal physiology
gonadotrophin
hormone free
secretion
estradiol
Źródło:: Journal of Physiology and Pharmacology; 1995, 46, 1
0867-5910
Pojawia się w:: Journal of Physiology and Pharmacology
Dostawca treści:: Biblioteka Nauki

Artykuł

Zmień widok

na półce

Skocz do pozycji: 8.

Tytuł:: Molecular basis of mechanisms of steroid resistance in children with nephrotic syndrome
Autorzy:: Świerczewska, Monika
Ostalska-Nowicka, Danuta
Kempisty, Bartosz
Nowicki, Michał
Zabel, Maciej
Powiązania:: https://bibliotekanauki.pl/articles/1039528.pdf
Data publikacji:: 2013
Wydawca:: Polskie Towarzystwo Biochemiczne
Tematy:: nephrotic syndrome
glucocorticoid receptor
steroid resistance
polymorphisms
Opis:: Steroid therapy, due to a wide range of anti-inflammatory properties of steroids, is a basic field of treatment in many human diseases including the nephrotic syndrome in children. However, not all patients respond positively to therapy which divides them into steroid sensitive (SS) and steroid resistance (SR) individuals. Many potential factors associated with steroid resistance have been identified so far. It seems that genetic factors associated with glucocorticoid receptor α (GRα), the structure of heterocomplex of GR as well as glycoprotein P or cytochrome P450 may play a role in the induction of glucocorticoid resistance. Here we described several of the molecular mechanisms, which can regulate glucocorticoid sensitivity and resistance. Moreover, we presented genetic defects, which can lead to various effects of treatment and, in a longer perspective, enable clinicians to individualize therapies.
Źródło:: Acta Biochimica Polonica; 2013, 60, 3; 339-344
0001-527X
Pojawia się w:: Acta Biochimica Polonica
Dostawca treści:: Biblioteka Nauki

Artykuł

Zmień widok

na półce

Skocz do pozycji: 9.

Tytuł:: Polymorphic variants of MIF gene and prognosis in steroid therapy in children with idiopathic nephrotic syndrome
Autorzy:: Świerczewska, Monika
Ostalska-Nowicka, Danuta
Kempisty, Bartosz
Szczepankiewicz, Aleksandra
Nowicki, Michał
Powiązania:: https://bibliotekanauki.pl/articles/1039333.pdf
Data publikacji:: 2014
Wydawca:: Polskie Towarzystwo Biochemiczne
Tematy:: nephrotic syndrome
steroid resistance
MIF gene
single nucleotide polymorphism
short tandem repeat
Opis:: Nephrotic syndrome (NS) is the most common reason of proteinuria in children and can be caused by the pathology of renal glomeruli. Steroid therapy is typically used in this disorder. It has been shown that MIF is a cytokine which counteracts the immunosuppressive properties of glucocorticoids. The aim of this study was looking for a correlation between MIF polymorphisms and genetic susceptibility to steroid resistance in children with INS (Idiopathic NS). Methods: The study was performed in 71 patients with INS including SRNS (steroid resistance nephrotic syndrome) (41) and SSNS (steroid sensitive nephrotic syndrome) (30) and in 30 control subjects. We employed Sanger sequencing and capillary electrophoresis. Linkage disequilibrium was made using Haploview and PHASE. Results: We didn't observe a statistical significance between SNPs detected in patients with INS and controls. Our studies revealed statistical significance for two polymorphisms: rs2070767C > T and rs2000466T > G between patients with SRNS and SSNS. The results for rs34383331T > A are close to being statistically significant. Statistical significance was revealed for CATT5/CATT6 genotype in SRNS group vs SSNS group (OR=4.604, 95%CI=1.356-15.632, p=0.0168). We found that the frequency of 5/X-CATT genotype compared with X/X-CATT genotype was significantly higher in SRNS patients vs SSNS (OR=3.167, 95%CI=1.046-9.585, p=0.0426). In linkage disequilibrium analysis we didn't show involvement in susceptibility to INS and steroid sensitive phenotype. Conclusions: Our results suggest that the role of MIF polymorphisms in the susceptibility to positive response to steroid therapy is still unresolved. It indicates that MIF may be involved in indirect and complex molecular mechanisms of steroid activity in hormone-dependent metabolic pathways in children with INS. Because of ambiguous findings, pleiotropic features of this cytokine require that more research should be undertaken.
Źródło:: Acta Biochimica Polonica; 2014, 61, 1; 67-75
0001-527X
Pojawia się w:: Acta Biochimica Polonica
Dostawca treści:: Biblioteka Nauki

Artykuł

Zmień widok

na półce

Skocz do pozycji: 10.

Tytuł:: The HPV16 E2 transcriptional regulator mode of action depends on the physical state of the viral genome
Autorzy:: Schmidt, Marcin
Olejnik, Agnieszka
Goździcka-Józefiak, Anna
Powiązania:: https://bibliotekanauki.pl/articles/1041324.pdf
Data publikacji:: 2005
Wydawca:: Polskie Towarzystwo Biochemiczne
Tematy:: E2
chromatin
transcription
HPV
retinol
steroid hormones
LCR
Opis:: Human papillomavirus (HPV) infection is a major risk factor for the development of cervical cancer. The HPV-induced immortalization of epithelial cell usually requires integration of the viral DNA into the host cell genome. The integration event causes disruption of the E2 gene and this is followed by overexpression of the E6 and E7 oncoproteins. The E2 protein is a transcription factor that regulates expression of the E6 and E7 oncoproteins by binding to four sites within the viral long control region. We used an in vitro cell culture model to explore the role of the E2 protein in the transcriptional control of the HPV16 long control region. Employing transient and stable transfection experiments we simulated the episomal and integrated states of the viral genome, respectively. We show that the E2 protein up-regulates E6/E7 transcription from episomal DNA but represses it in the case of integrated DNA. The activator function of the E2 protein seems to counteract the repressive chromatin structure formed over episomal DNA. Steroid hormones and retinol also modulate oncogene transcription differently depending on the physical structure of the viral DNA. Our data suggest regulatory mechanisms involving interactions between the E2 protein and nuclear hormone receptors.
Źródło:: Acta Biochimica Polonica; 2005, 52, 4; 823-832
0001-527X
Pojawia się w:: Acta Biochimica Polonica
Dostawca treści:: Biblioteka Nauki

Artykuł

Zmień widok

na półce

Skocz do pozycji: 11.

Tytuł:: Exogenous steroid hormones stimulate full development of autonomous endosperm in Arabidopsis thaliana
Autorzy:: Rojek, J.
Pawelko, L.
Kapusta, M.
Naczk, A.
Bohdanowicz, J.
Powiązania:: https://bibliotekanauki.pl/articles/59176.pdf
Data publikacji:: 2015
Wydawca:: Polskie Towarzystwo Botaniczne
Tematy:: steroid hormone
endosperm
Arabidopsis thaliana
apomixis
DNA methylation
Opis:: Most flowering plants, including important crops, require double fertilization to form an embryo and endosperm, which nourishes it. Independence from fertilization is a feature of apomictic plants that produce seeds, from which the plants that are clones of the mother plant arise. The phenomenon of apomixis occurs in some sexual plants under specific circumstances. Since the launch of a fertilization-independent mechanism is considered a useful tool for plant breeding, there have been efforts to artificially induce apomixis. We have been able to produce fertilization-independent endosperm in vitro in Arabidopsis over the last few years. This paper demonstrates the methods of improving the quality of the endosperm obtained using plant and mammalian steroid hormones. Additionally, it shows the study on the autonomous endosperm (AE) formation mechanism in vitro. This paper examines the effect of exogenous steroid hormones on unfertilized egg and central cell divisions in culture of unpollinated pistils of Arabidopsis Col-0 wild-type andfie-1 mutant. All media with hormones used (estrone, androsterone, progesterone, and epibrassinolide) stimulated central cell divisions and fertilization-independent endosperm development. The stages of AE development followed the pattern of Arabidopsis thaliana wild type after fertilization. Subsequent stages of AE were observed from 2-nuclear up to cellular with the most advanced occurring on medium with 24-epibrassinolide and progesterone. The significant influence of mammalian sex hormones on speed of AE development and differentiation was noticed. Using restriction analysis, the changes in methylation of FIE gene was established under in vitro condition. The authors of this paper showed that Arabidopsis thaliana has a high potency to fertilization-independent development.
Źródło:: Acta Societatis Botanicorum Poloniae; 2015, 84, 2
0001-6977
2083-9480
Pojawia się w:: Acta Societatis Botanicorum Poloniae
Dostawca treści:: Biblioteka Nauki

Artykuł

Zmień widok

na półce

Skocz do pozycji: 12.

Tytuł:: Roux-en-Y gastric bypass as a cure of iatrogenic steroid-induced diabetes
Autorzy:: Poznanska, Grazyna
Hogendorf, Piotr
Czupryniak, Leszek
Smolewski, Piotr
Grząsiak, Oliwia
Szmiel, Aneta
Kasiarz, Anna
Strzelczyk, Janusz
Durczyński, Adam
Powiązania:: https://bibliotekanauki.pl/articles/1392077.pdf
Data publikacji:: 2019
Wydawca:: Index Copernicus International
Tematy:: bariatric surgery
cure
iatrogenic diabetes
Roux-en-Y gastric bypass
steroid induced diabetes
treatment
Opis:: Background: Steroid-induced diabetes (SIDM) is a frequently found clinical condition since steroid-based therapies continue to be widely used in hospital and ambulatory care. Recommended optimal treatment of SIDM includes similar glucose lowering strategies as in type 2 diabetes. This typical management cannot cure the disease, it can only control blood glucose. Recently, bariatric surgery has emerged as an effective treatment for type 2 diabetes mellitus. However, up to now, the usefulness of bariatric surgery in treatment of SIDM has not been evaluated. Case report: A 49-year-old female oncologic patient with steroid induced diabetes was referred for surgical treatment to the Department of General and Transplant Surgery in November 2009. Six years earlier, she underwent successful oncologic treatment with cladribine and high doses of steroids due to hairy cell leukemia. Finally complete hematologic remission with normalization of morphology and reduction of spleen size has been obtained. Prior to steroid treatment, blood glucose and urine examinations were within normal range. The patient was non-obese and had no family history of diabetes. Nevertheless, the patient developed diabetes secondary to corticosteroid therapy, poorly controlled by oral hypoglycemic agent (acarbosum), successfully converted to insulin therapy. Upon admission to the Department of General and Transplant Surgery, the patient was treated with 58 units of insulin per day. The patient was scheduled for Roux-en-Y gastric bypass (RYGB). Insulin was withdrawn immediately after the surgery and within six months after the surgery, plasma glucose and glycated hemoglobin (HbA1c-5.5%) levels reached and remained within normal range. Currently, eight years after surgery, body weight and BMI are 80 kg and 27.68 kg/m2, respectively. Plasma glucose and glycated hemoglobin are also normal. Importantly, from an oncological point of view, the patient has remained in continuous complete remission since October 2003. Conclusions: Our report is the first to our knowledge describing the effect of gastric bypass surgery on SIDM in a patient with prior hematologic malignancy. It proves that surgically altered anatomy of the small intestine improves glucose homeostasis previously disturbed with pro-diabetic medication.
Źródło:: Polish Journal of Surgery; 2019, 91, 5; 52-54
0032-373X
2299-2847
Pojawia się w:: Polish Journal of Surgery
Dostawca treści:: Biblioteka Nauki

Artykuł

Zmień widok

na półce

Skocz do pozycji: 13.

Tytuł:: Enzymatyczne reakcje rozszczepienia wiązania C–C : zastosowanie w syntezie związków zapachowych, farmaceutyków oraz w bioremediacji
Enzymatic reactions of the C–C bond cleavage : applications in synthesis of aroma compounds, pharmaceuticals and in bioremediation
Autorzy:: Panek, A.
Milecka-Tronina, N.
Świzdor, A.
Powiązania:: https://bibliotekanauki.pl/articles/172055.pdf
Data publikacji:: 2015
Wydawca:: Polskie Towarzystwo Chemiczne
Tematy:: β-oksydacja
wanilina
γ-dekalakton
metyloketony
leki steroidowe
bioremediacja
β-oxidation
vanillin
γ-decalactone
methyl ketones
steroid drugs
bioremediation
Opis:: The microorganisms are able to utilize natural and synthetic compounds of broad structural diversity as a source of carbon and energy, converting these substrates into low molecular weight products (mainly H2O, CO2 and NH3). The main role in this metabolism is played by the enzymes that catalyze reactions of the C–C bond cleavage. Such reactions are the key step of the primary metabolism of fatty acids in eukaryotic cells by the β-oxidation. The enzymatic systems associated with the C–C bond cleavage have been applied in the synthesis of valuable natural products and in the bioremediation processes. Microbial transformations of natural compounds, in which the reactions of β-oxidation cycle are used, allow the formation of natural aromatic compounds (used as food additives), pharmaceuticals and ingredients of cosmetic compositions. Using this path one can obtain methyl ketones (e.g. responsible for the characteristic smell of cheeses), γ-lactones determining the scent of several popular fruits, and vanillin. A modification of the natural steroids: saponins, alkaloids, sterols, bile acids to products useful in the synthesis of steroid drugs is the most important area of use of the enzymatic C–C bond cleavage, due to the practical significance of the products. Enzymes that catalyze the C–C bonds cleavage are important in the process of biodegradation of toxic aromatic hydrocarbons and their derivatives (bioremediation).
Źródło:: Wiadomości Chemiczne; 2015, 69, 5-6; 337-368
0043-5104
2300-0295
Pojawia się w:: Wiadomości Chemiczne
Dostawca treści:: Biblioteka Nauki

Artykuł

Zmień widok

na półce

Skocz do pozycji: 14.

Tytuł:: Arbutin in Serratula quinquefolia M.B. [Asteraceae]
Autorzy:: Nowak, G
Nawrot, J.
Latowski, K.
Powiązania:: https://bibliotekanauki.pl/articles/58892.pdf
Data publikacji:: 2009
Wydawca:: Polskie Towarzystwo Botaniczne
Tematy:: arbutin
chemotaxonomy
steroid compound
Compositae
Serratula quinquefolia
Opis:: Genus Serratula is known for the presence of steroid compounds which belong to the group of ecdysones. Former phytochemical works from the late sixties and early seventies indicate, in some Serratula species, the occurrence of a phenolic glycoside-arbutin. This has been confirmed in the present work through finding an α,β-arbutin anomer in Serratula quinquefolia M.B. New botanical data concerning the classification of genus Serratula suggest that the species in question should be regarded as belonging to genus Klasea (currently a section of genus Serratula). There has been an attempt to find a key to the chemical division within the taxons.
Źródło:: Acta Societatis Botanicorum Poloniae; 2009, 78, 2; 137-140
0001-6977
2083-9480
Pojawia się w:: Acta Societatis Botanicorum Poloniae
Dostawca treści:: Biblioteka Nauki

Artykuł

Zmień widok

na półce

Skocz do pozycji: 15.

Tytuł:: Evaluation of changes in the growth and chemical constituents of Anoectochilus formosanus Hayata grown under hydroponic conditions
Autorzy:: Nguyen, H.C.
Nhu, T.Q.M.
Dung, P.V.
Hieu, N.D.
Tuan, T.T.
Huyen, P.X.
Truong, D.-H.
Powiązania:: https://bibliotekanauki.pl/articles/80522.pdf
Data publikacji:: 2018
Wydawca:: Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:: Anoectochilus formosanus
medicinal plant
mineral nutrition
hydroponic cultivation
chemical constituent
antioxidant activity
phytochemical screening
alkaloid content
flavonoids
glycoside
terpenoid
steroid
Źródło:: BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology; 2018, 99, 4
0860-7796
Pojawia się w:: BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology
Dostawca treści:: Biblioteka Nauki

Artykuł

Zmień widok

na półce

Informacja

Wyszukujesz frazę "steroid" wg kryterium: Temat

Źródło danych

Dostawca treści

Kolekcja

Rok wydania

Wydawca

Temat

Autor

Typ dokumentu

Język