Temat: steroid - Katalog OPAC zbiorów

Skocz do pozycji: 1.

Tytuł:: The pattern of steroid secretion by perifused preovulatory rat follicles
Autorzy:: Szoltys, M
Powiązania:: https://bibliotekanauki.pl/articles/70002.pdf
Data publikacji:: 1995
Wydawca:: Polskie Towarzystwo Fizjologiczne
Tematy:: radioimmunoassay
steroid production
progesterone
rat follicle
steroid
endocrinology
steroid analysis
ovulation
androgen
animal physiology
gonadotrophin
hormone free
secretion
estradiol
Źródło:: Journal of Physiology and Pharmacology; 1995, 46, 1
0867-5910
Pojawia się w:: Journal of Physiology and Pharmacology
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 2.

Tytuł:: Adrenomyeloneuropathy – a case report
Autorzy:: Leksa, Natalia
Aebisher, David
Galiniak, Sabina
Uberman-Kluz, Dominika
Bartosz, Serweryn
Bartusik-Aebisher, Dorota
Powiązania:: https://bibliotekanauki.pl/articles/454995.pdf
Data publikacji:: 2019
Wydawca:: Uniwersytet Rzeszowski. Wydawnictwo Uniwersytetu Rzeszowskiego
Tematy:: adrenoleukodystrophy
fatty acids
steroid therapy
Opis:: Introduction. Adrenoleukodystrophy is a genetic disorder linked to the X chromosome, in which the peroxisomal beta-oxidation process is disturbed. It is a metabolic disease that results in the accumulation of very long chain fatty acids (VLCFAs - very long chain fatty acids) responsible for the symptoms of damage to the adrenal cortex, gonads and the brain. Aim. A clinical case is reported. Description of case. This article describes the case of a 64-year-old woman who had neurological symptoms for many years, gradually increasing without significant improvement after the treatment (periodic steroid therapy). Conclusion. Based on tests (including the determination of the ABCD1 gene and very long chain fatty acids - VLCFA), adrenoleukodystrophy was suspected.
Źródło:: European Journal of Clinical and Experimental Medicine; 2019, 3; 274-276
2544-2406
2544-1361
Pojawia się w:: European Journal of Clinical and Experimental Medicine
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 3.

Tytuł:: Molecular basis of mechanisms of steroid resistance in children with nephrotic syndrome
Autorzy:: Świerczewska, Monika
Ostalska-Nowicka, Danuta
Kempisty, Bartosz
Nowicki, Michał
Zabel, Maciej
Powiązania:: https://bibliotekanauki.pl/articles/1039528.pdf
Data publikacji:: 2013
Wydawca:: Polskie Towarzystwo Biochemiczne
Tematy:: nephrotic syndrome
glucocorticoid receptor
steroid resistance
polymorphisms
Opis:: Steroid therapy, due to a wide range of anti-inflammatory properties of steroids, is a basic field of treatment in many human diseases including the nephrotic syndrome in children. However, not all patients respond positively to therapy which divides them into steroid sensitive (SS) and steroid resistance (SR) individuals. Many potential factors associated with steroid resistance have been identified so far. It seems that genetic factors associated with glucocorticoid receptor α (GRα), the structure of heterocomplex of GR as well as glycoprotein P or cytochrome P450 may play a role in the induction of glucocorticoid resistance. Here we described several of the molecular mechanisms, which can regulate glucocorticoid sensitivity and resistance. Moreover, we presented genetic defects, which can lead to various effects of treatment and, in a longer perspective, enable clinicians to individualize therapies.
Źródło:: Acta Biochimica Polonica; 2013, 60, 3; 339-344
0001-527X
Pojawia się w:: Acta Biochimica Polonica
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 4.

Tytuł:: Arbutin in Serratula quinquefolia M.B. [Asteraceae]
Autorzy:: Nowak, G
Nawrot, J.
Latowski, K.
Powiązania:: https://bibliotekanauki.pl/articles/58892.pdf
Data publikacji:: 2009
Wydawca:: Polskie Towarzystwo Botaniczne
Tematy:: arbutin
chemotaxonomy
steroid compound
Compositae
Serratula quinquefolia
Opis:: Genus Serratula is known for the presence of steroid compounds which belong to the group of ecdysones. Former phytochemical works from the late sixties and early seventies indicate, in some Serratula species, the occurrence of a phenolic glycoside-arbutin. This has been confirmed in the present work through finding an α,β-arbutin anomer in Serratula quinquefolia M.B. New botanical data concerning the classification of genus Serratula suggest that the species in question should be regarded as belonging to genus Klasea (currently a section of genus Serratula). There has been an attempt to find a key to the chemical division within the taxons.
Źródło:: Acta Societatis Botanicorum Poloniae; 2009, 78, 2; 137-140
0001-6977
2083-9480
Pojawia się w:: Acta Societatis Botanicorum Poloniae
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 5.

Tytuł:: Oznaczanie hormonów steroidowych w materiale biologicznym
Autorzy:: Kotłowska, A.
Szulfer, J.
Kamysz, W.
Powiązania:: https://bibliotekanauki.pl/articles/274307.pdf
Data publikacji:: 2010
Wydawca:: Roble
Tematy:: oznaczanie hormonów steroidowych
hormony steroidowe
steroid hormones marking
Źródło:: LAB Laboratoria, Aparatura, Badania; 2010, 15, 4; 20-23
1427-5619
Pojawia się w:: LAB Laboratoria, Aparatura, Badania
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 6.

Tytuł:: The HPV16 E2 transcriptional regulator mode of action depends on the physical state of the viral genome
Autorzy:: Schmidt, Marcin
Olejnik, Agnieszka
Goździcka-Józefiak, Anna
Powiązania:: https://bibliotekanauki.pl/articles/1041324.pdf
Data publikacji:: 2005
Wydawca:: Polskie Towarzystwo Biochemiczne
Tematy:: E2
chromatin
transcription
HPV
retinol
steroid hormones
LCR
Opis:: Human papillomavirus (HPV) infection is a major risk factor for the development of cervical cancer. The HPV-induced immortalization of epithelial cell usually requires integration of the viral DNA into the host cell genome. The integration event causes disruption of the E2 gene and this is followed by overexpression of the E6 and E7 oncoproteins. The E2 protein is a transcription factor that regulates expression of the E6 and E7 oncoproteins by binding to four sites within the viral long control region. We used an in vitro cell culture model to explore the role of the E2 protein in the transcriptional control of the HPV16 long control region. Employing transient and stable transfection experiments we simulated the episomal and integrated states of the viral genome, respectively. We show that the E2 protein up-regulates E6/E7 transcription from episomal DNA but represses it in the case of integrated DNA. The activator function of the E2 protein seems to counteract the repressive chromatin structure formed over episomal DNA. Steroid hormones and retinol also modulate oncogene transcription differently depending on the physical structure of the viral DNA. Our data suggest regulatory mechanisms involving interactions between the E2 protein and nuclear hormone receptors.
Źródło:: Acta Biochimica Polonica; 2005, 52, 4; 823-832
0001-527X
Pojawia się w:: Acta Biochimica Polonica
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 7.

Tytuł:: SOCS3 is epigenetically up-regulated in steroid resistant nephrotic children
Autorzy:: Zaorska, Katarzyna
Zawierucha, Piotr
Ostalska-Nowicka, Danuta
Nowicki, Michał
Powiązania:: https://bibliotekanauki.pl/articles/1038853.pdf
Data publikacji:: 2016
Wydawca:: Polskie Towarzystwo Biochemiczne
Tematy:: methylation
nephrotic syndrome
single nucleotide polymorphism
steroid resistance
Opis:: Background. The mechanism of steroid resistance in children with the nephrotic syndrome is yet unknown. About 20% of patients demonstrate steroid unresponsiveness and progress to end stage renal disease. Aberrant SOCS3 and SOCS5 expression in steroid resistant and sensitive patients has previously been demonstrated. Here, we investigate genetic and epigenetic mechanisms of regulation of SOCS3 and SOCS5 transcription in nephrotic children. Methods. 76 patients with the nephrotic syndrome (40 steroid resistant and 36 steroid sensitive) and 33 matched controls were included in this study. We performed genotyping of a total of 34 single nucleotide polymorphisms for SOCS3 and SOCS5 promoters and evaluated their methylation status using MS-PCR and QMSP methods. Results. Steroid resistant patients had a significantly lower methylation of one region of SOCS3 promoter in comparison with steroid sensitive patients and controls (p < 0.0001). However, the relative methylation level in the steroid sensitive patients and controls differed significantly even before the first steroid dose (p = 0.001758). Other SOCS3 and SOCS5 promoter regions displayed no differences in methylation or were fully methylated/unmethylated in all study groups, showing site-specific methylation. The allele and genotype distribution for SOCS3 and SOCS5 markers did not differ statistically between the groups. Conclusions. We demonstrate an epigenetic mechanism of SOCS3 up-regulation in steroid resistant children with the nephrotic syndrome. The assessment of methylation/unmethylation of SOCS3 promoter might be an early marker for steroid responsiveness in NS patients.
Źródło:: Acta Biochimica Polonica; 2016, 63, 1; 131-138
0001-527X
Pojawia się w:: Acta Biochimica Polonica
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 8.

Tytuł:: Exogenous steroid hormones stimulate full development of autonomous endosperm in Arabidopsis thaliana
Autorzy:: Rojek, J.
Pawelko, L.
Kapusta, M.
Naczk, A.
Bohdanowicz, J.
Powiązania:: https://bibliotekanauki.pl/articles/59176.pdf
Data publikacji:: 2015
Wydawca:: Polskie Towarzystwo Botaniczne
Tematy:: steroid hormone
endosperm
Arabidopsis thaliana
apomixis
DNA methylation
Opis:: Most flowering plants, including important crops, require double fertilization to form an embryo and endosperm, which nourishes it. Independence from fertilization is a feature of apomictic plants that produce seeds, from which the plants that are clones of the mother plant arise. The phenomenon of apomixis occurs in some sexual plants under specific circumstances. Since the launch of a fertilization-independent mechanism is considered a useful tool for plant breeding, there have been efforts to artificially induce apomixis. We have been able to produce fertilization-independent endosperm in vitro in Arabidopsis over the last few years. This paper demonstrates the methods of improving the quality of the endosperm obtained using plant and mammalian steroid hormones. Additionally, it shows the study on the autonomous endosperm (AE) formation mechanism in vitro. This paper examines the effect of exogenous steroid hormones on unfertilized egg and central cell divisions in culture of unpollinated pistils of Arabidopsis Col-0 wild-type andfie-1 mutant. All media with hormones used (estrone, androsterone, progesterone, and epibrassinolide) stimulated central cell divisions and fertilization-independent endosperm development. The stages of AE development followed the pattern of Arabidopsis thaliana wild type after fertilization. Subsequent stages of AE were observed from 2-nuclear up to cellular with the most advanced occurring on medium with 24-epibrassinolide and progesterone. The significant influence of mammalian sex hormones on speed of AE development and differentiation was noticed. Using restriction analysis, the changes in methylation of FIE gene was established under in vitro condition. The authors of this paper showed that Arabidopsis thaliana has a high potency to fertilization-independent development.
Źródło:: Acta Societatis Botanicorum Poloniae; 2015, 84, 2
0001-6977
2083-9480
Pojawia się w:: Acta Societatis Botanicorum Poloniae
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 9.

Tytuł:: Prenatal glucocorticoids can programme postnatal development
Autorzy:: Tomaszewska, E.
Dobrowolski, P.
Powiązania:: https://bibliotekanauki.pl/articles/3123.pdf
Data publikacji:: 2011
Wydawca:: Instytut Medycyny Wsi
Tematy:: prenatal glucocorticoid
glucocorticoid
postnatal development
bone
dexamethasone
steroid hormone
Źródło:: Journal of Pre-Clinical and Clinical Research; 2011, 05, 1
1898-2395
Pojawia się w:: Journal of Pre-Clinical and Clinical Research
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 10.

Tytuł:: Qa-SNARE protein SYP22 negatively regulates brassinosteroid signaling in the dark
Autorzy:: Yao, T.S.
Zhu, X.F.
Jung, J.H.
Xuan, Y.H.
Powiązania:: https://bibliotekanauki.pl/articles/19201.pdf
Data publikacji:: 2015
Wydawca:: Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:: SNARE protein
SYP22 gene
brassinosteroid
steroid hormone
signalling
dark
Arabidopsis
Źródło:: Acta Biologica Cracoviensia. Series Botanica; 2015, 57, 2
0001-5296
Pojawia się w:: Acta Biologica Cracoviensia. Series Botanica
Dostawca treści:: Biblioteka Nauki

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