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Tytuł:
Comparative analysis of numerical simulations of blood flow through the segment of an artery in the presence of stenosis
Autorzy:
Shaikh, Fozia
Shaikh, Asif Ali
Hincal, Evren
Qureshi, Sania
Powiązania:
https://bibliotekanauki.pl/articles/24201504.pdf
Data publikacji:
2023
Wydawca:
Politechnika Częstochowska. Wydawnictwo Politechniki Częstochowskiej
Tematy:
incompressible
isothermal
blood flow
stenosis
finite element method
izotermiczność
przepływ krwi
zwężenie
metoda elementów skończonych
Opis:
A mathematical model is developed to study the characteristics of blood flowing through an arterial segment in the presence of a single and a couple of stenoses. The governing equations accompanied by an appropriate choice of initial and boundary conditions are solved numerically by Taylor Galerkin’s time-stepping equation, and the numerical stability is checked. The pressure, velocity, and stream functions have been solved by Cholesky’s method. Furthermore, an in-depth study of the flow pattern reveals the separation of Reynolds number for the 30 and 50% blockage of single stenosis and 30% blockage of multi-stenosis. The present results predict the excess pressure drop across the stenosis site than it does for the inlet of the artery with single and multiple stenosis and the increase in the velocity is observed at the center of the artery.
Źródło:
Journal of Applied Mathematics and Computational Mechanics; 2023, 22, 2; 49--61
2299-9965
Pojawia się w:
Journal of Applied Mathematics and Computational Mechanics
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Wybrane choroby kręgosłupa w praktyce lekarza rodzinnego
Selected spine disorders in a family doctor’s practice
Autorzy:
Citko, Anna
Owsieniuk, Irena
Powiązania:
https://bibliotekanauki.pl/articles/2076838.pdf
Data publikacji:
2022-06-01
Wydawca:
Wydawnictwo Naukowe Medyk sp. z o.o.
Tematy:
choroby kręgosłupa
guzki Schmorla
stenoza kanału kręgowego
zespół ogona końskiego
choroba Baastrupa
spine disorders
Schmorl’s nodes
spinal canal stenosis
cauda equina syndrome
Baastrup’s disease
Opis:
Choroby kręgosłupa i związany z nimi ból są istotnym problemem medycznym, społecznym i ekonomicznym z uwagi na ich powszechne występowanie i ciągle wzrastającą liczbę chorych w ogólnej populacji. Stanowią jedną z najczęstszych przyczyn zgłoszeń do lekarza rodzinnego. Należy zwrócić uwagę na fakt, że społeczeństwo będzie miało coraz większe zapotrzebowanie na leczenie schorzeń kręgosłupa, w tym stenozy kanału kręgowego, a także deformacji kręgosłupa. Należy jednak nie zapominać o rzadszych przyczynach bólów kręgosłupa, na przykład chorobie Baastrupa czy też uogólnionej samoistnej hiperostozie szkieletu. Dlatego podstawowa wiedza na najwyższym poziomie na temat etiopatogenezy, objawów klinicznych, diagnostyki i leczenia chorób kręgosłupa jest niezbędna dla lekarzy rodzinnych. Guzki Schmorla to wklęśnięcia jąder miażdżystych w głąb trzonów kręgowych, tworzące charakterystyczne wpuklenie o sklerotycznym dnie. Mnogie guzki Schmorla są zaliczane do charakterystycznych objawów choroby Scheuermanna. Choroba Scheuermanna jest hiperkifozą piersiową lub piersiowo-lędźwiową spowodowaną sklinowaceniem trzonów kręgowych. Stenoza kanału kręgowego to pojęcie używane dla określenia objawów strukturalnego zwężenia kanału kręgowego. Jednym z głównych czynników ryzyka wystąpienia tego schorzenia jest przepuklina dysku w odcinku lędźwiowo-krzyżowym kręgosłupa. Chory nie toleruje pozycji wyprostu. Dodatkowo zgłasza bolesność (osłabienie siły mięśniowej) kończyn dolnych (tzw. zespół chromania neurogennego). Zespół ogona końskiego to zespół objawów powodowanych przez uszkodzenie korzeni lędźwiowych L2-L5, korzeni krzyżowych i splotu guzicznego. Chory może odczuwać ból krzyża, w tym ból o charakterze korzeniowym. Choroba Baastrupa to entezopatia dotycząca przyczepów więzadeł międzykolcowych, prowadząca do rozwoju zmian zwyrodnieniowych. Uogólniona samoistna hiperostoza szkieletu charakteryzuje się kostnieniem w okolicy przyczepów ścięgnistych, więzadeł oraz w miejscu połączenia torebki stawowej z kością.
Spine disorders and related pain constitute a significant medical, social and economic issue due to the common presence and the constantly increasing number of cases in the general population. These are the major reasons why patients report to a family doctor. Attention should be drawn to the fact that society will require an increasing demand for the treatment of spinal disorders, including spinal canal stenosis and also spine deformations. Causes of dorsalgia should also be borne in mind, for instance, Baastrup disease and diffuse idiopathic skeletal hyperostosis. Therefore, elementary knowledge at the highest level concerning etiopathogenesis, clinical symptoms, diagnostics and the treatment of spinal disorders is necessary for family doctors. Schmorl’s nodes occur when the nucleus pulposus protrudes into the vertebral bodies, thus creating a characteristic bulging of the sclerotic base. Multiple Schmorl’s nodes are characterised as the symptoms of Scheuermann’s disease. Scheuermann’s disease is a thoracic or thoracolumbar hyperkyphosis resulting from vertebral body wedging. Spinal canal stenosis is a term describing the symptoms of structural spinal canal stenosis. A herniated disc in the lumbosacral spine constitutes one of the major risk factors. The patient does not tolerate the upright position. They also report pain (weakened muscle power) in the lower extremities (the so-called neurogenic claudication syndrome). Cauda equina syndrome is a set of symptoms caused by L2-L5 lumbar roots, sacral roots and coccygeal plexus damage. The patient may suffer from sacral pain, including that of a radicular nature. Baastrup’s disease is the enthesopathy of interspinous ligament attachments resulting in degenerative lesions development. Diffuse idiopathic skeletal hyperostosis is characterised by ossification within the tendinous attachments, ligaments and at the place of the joint capsule and bone attachment.
Źródło:
Gabinet Prywatny; 2022, 281, 02; 21-25
2353-8600
Pojawia się w:
Gabinet Prywatny
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Effects of stenosis and dilatation on flow of blood mixed with suspended nanoparticles: a study using homotopy technique
Autorzy:
Sudha, T.
Umadevi, C.
Dhange, M.
Manna, S.
Misra, J. C.
Powiązania:
https://bibliotekanauki.pl/articles/1839885.pdf
Data publikacji:
2021
Wydawca:
Uniwersytet Zielonogórski. Oficyna Wydawnicza
Tematy:
przepływ krwi
zwężenie tętnicy
ciśnienie krwi
stenosis
dilatation
couple stress fluid
impedance
shear stress
Opis:
The paper deals with a theoretical study on blood flow in a stenosed segment of an artery, when blood is mixed with nano-particles. Blood is treated here as a couple stress fluid. Stenosis is known to impede blood flow and to be the cause of different cardiac diseases. Since the arterial wall is weakened due to arterial stenosis, it may lead to dilatation /aneurysm. The homotopy perturbation technique is employed to determine the solution to the problem for the case of mild stenosis. Analytical expressions for velocity, shear stress at the wall, pressure drop, and flow resistance are derived. The impact of different physical constants on the wall shear stress and impedance of the fluid is examined by numerical simulation. Streamline patterns of the nanofluid are investigated for different situations.
Źródło:
International Journal of Applied Mechanics and Engineering; 2021, 26, 1; 251-265
1734-4492
2353-9003
Pojawia się w:
International Journal of Applied Mechanics and Engineering
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Aortic valve stenosis and its recent treatment techniques
Autorzy:
Witkowski, Adam
Powiązania:
https://bibliotekanauki.pl/articles/1916637.pdf
Data publikacji:
2020
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
acquired aortic valve stenosis
transcatheter aortic valve implantation
comorbidities
Opis:
Aortic stenosis is the most common acquired valvular heart disease. Aortic stenosis has growing prevalence in people older than 75 years and natural course of disease is characterized by high mortality rate. According to epidemiological data all patients with aortic stenosis will die after 2–5 years from the first signs of disease if not undergo aortic valve replacement. However, even 40% of patients do not have surgery because of comorbidities related to advanced age. This was the main reason why in 80- and 90-ties of XX century there were intensive attempt to developed an alternative, less invasive treatment methodology for people with aortic stenosis and comorbidities and at high surgical risk. Transcatheter aortic valve implantation (TAVI) was introduced by Dr Alain Cribier in February 2nd, 2002 in Rouen, France. Since that day different aortic transcatheter bioprostheses were used in many randomized clinical trials comparing their safety and effectiveness versus surgical aortic valve replacement. Gradually, it became clear that in all older patients in all risk groups TAVI was equally or even more safe and effective than surgery. Complications after TAVI are relatively rare, but some of them are life-threatening. Heart Team plays a key role in patients selection to TAVI.
Źródło:
Nauka; 2020, 2
1231-8515
Pojawia się w:
Nauka
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Carotid access in Transcatheter Aortic Valve Implantation – an alternative to the gold standard. A single-center experience
Autorzy:
Stańska, Aleksandra
Wierzbowska, Aleksandra
Targoński, Radosław
Karolak, Wojciech
Mickiewicz, Agnieszka
Jaguszewski, Miłosz
Jagielak, Dariusz
Powiązania:
https://bibliotekanauki.pl/articles/895733.pdf
Data publikacji:
2020-01-09
Wydawca:
Gdański Uniwersytet Medyczny
Tematy:
transcatheter aortic valve implantation
aortic stenosis
carotid artery
elderly
Opis:
Background: Transfemoral access is regarded as the TAVI gold standard for the transcatheter aortic valve implantation (TAVI) procedure. However, other options for vascular access have developed in the last few years. Access via the carotid artery is one such alternative. Materials and methods: The study included 9 elderly patients who underwent transcarotid TAVI procedure at the Cardiac and Vascular Surgery Department of the Medical University of Gdańsk. Procedures were performed by a local Heart Team in a hybrid operating room under general anesthesia. Data was collected before the implantation and at discharge. Results: The mean patients’ age was 81 years of age (64-88) and the mean logistic EuroSCORE was 10.8 (7-16). Implantations were performed with 100% device success rate. Intra-operative valve-in-valve procedure was performed in one patient; there were no access-related and valve-related complications during the surgery. Post-procedural complications included minor bleeding, hematoma and pneumothorax. Echocardiographic parameters were significantly improving after the procedure. The mean hospital stay was 5 days (2-7 days). Conclusions: Transcatheter aortic valve implantation via the carotid artery appears to be safe and effective alternative to standard TAVI vascular access.
Źródło:
European Journal of Translational and Clinical Medicine; 2019, 2, 2; 80-84
2657-3148
2657-3156
Pojawia się w:
European Journal of Translational and Clinical Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Endovascular technologies and reconstructive interventions on profound femoral artery at revascularization of multilevel stenotic-occlusive process of infrainguinal arterial channel
Autorzy:
Herasymiuk, Nazar I.
Husak, Mykhailo O.
Venher, Ihor K.
Kovalskyy, Dmytro V.
Loyko, Ihor I.
Selskyy, Boryslav P.
Powiązania:
https://bibliotekanauki.pl/articles/1580660.pdf
Data publikacji:
2020-01-27
Wydawca:
Uniwersytet Mikołaja Kopernika w Toruniu. Wydział Nauk o Ziemi i Gospodarki Przestrzennej. Katedra Kultury Fizycznej
Tematy:
arterial stenosis
revascularization
shunting interventions
Opis:
Introduction. Number of patients with obliterating lesions of the aorta and main arteries of the lower extermities has been steadily increasing every year. When choosing the scope of surgical treatment all the features of the multilevel stenotic-occlusive process of the infrainguinal arterial bed should be taken into account. Purpose. To improve the results of revascularization of the infrainguinal arterial bed by applying surgical intervention on profound femoral artery and endovascular methods to restore permeability of the outflow arteries. Materials and methods. The work is based on the results of examination and surgical treatment of 264 patients with stenotic-occlusive process of the infrainguinal arterial bed. There were four groups of patients. The basis of revascularization interventions on the infranguinal artery was shunt surgery. Bypass surgery was performed using a reverse autovein. The combined shunt was used for localization of the distal anastomosis at the level of the popliteal, shin arteries, tibioperinel trunk. Results. In atherosclerotic stenotic-occlusive lesions of the infrainguinal arterial bed of the lower extremity, the volume of surgical treatment depends on the level of the occlusive process, the functional state of the PFA and the blood flow pathways. And the method of surgical intervention in shunt interventions is determined by the type of distal lesion and the level of imposition of distal and proximal anastomoses. Conclusion. The use of endovascular methods of revascularization and reconstructive interventions on PFA in combination with femoral-distal shunt operations contributes to good and satisfactory results of surgical treatment of stenotic-occlusive processes of the infrainguinal arterial bed.
Źródło:
Journal of Education, Health and Sport; 2021, 11, 1; 153-162
2391-8306
Pojawia się w:
Journal of Education, Health and Sport
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Evaluation of the safety and effects of pregabalin premedication on sleep quality, haemodynamic changes and pain in elderly patients with comorbidities undergoing spinal stenosis
Autorzy:
Kilic, E.T.
Powiązania:
https://bibliotekanauki.pl/articles/2098198.pdf
Data publikacji:
2020
Wydawca:
Instytut Medycyny Wsi
Tematy:
pregabalin
stenosis
intraoperative monitoring
analgesia
sleep quality
hemodynamic change
pain
elderly patient
Opis:
Objective. The aim of the study was to determine the effects of pregabalin premedication on preoperative sleep quality, intraoperative haemodynamic parameters, anesthesia consumption, blood loss, and postoperative pain control in patients over 65 years of age who had undergone surgery for spinal stenosis. The study also aimed to determine whether pregabalin premedication was safe for that age group and compare its effects with those of diazepam. Materials and method. The retrospective study was conducted in a single centre after approval by the local Ethics Committee. The study sample consisted of 95 patients over 65 years of age who had undergone surgery for spinal stenosis. The sample was divided into two groups: Pregabalin premedication patients (PG; n = 45) and Diazepam patients (D; n = 51). Demographic data, American Society of Anesthesiologists (ASA) scores, comorbidities, indications for operation, pre- operative sleep quality, total anaesthesia consumption during surgery, intraoperative haemodynamic parameters and blood loss, time to leaving the post- anaesthetic care unit (Aldrete’s > 9), postoperative visual analog pain scale (VAS), total fentanyl consumption via a patient-controlled analgesia (PCA) device, additional demand for analgesic, first mobilization, first oral intake, and side-effects were recorded. Results. Participants did not significantly differ by demographic data and duration of surgery. The PG group had better sleep quality, lower systolic and diastolic blood pressure, heart rate, intraoperative bleeding, postoperative VAS scores, additional analgesic consumption, and total fentanyl consumption via a PCA, and earlier mobilization and oral intake than the D group. No serious side-effects were observed in the groups. Conclusion. Pregabalin premedication is a safe and effective alternative medication for patients over 65 years of age.
Źródło:
Journal of Pre-Clinical and Clinical Research; 2020, 14, 4; 111-116
1898-2395
Pojawia się w:
Journal of Pre-Clinical and Clinical Research
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Usage of excimer laser in coronary and peripheral artery stenosis – analysis of its safety aspect
Autorzy:
Machowiec, P.A.
Reka, G.
Piecewicz-Szczesna, H.
Powiązania:
https://bibliotekanauki.pl/articles/2098216.pdf
Data publikacji:
2020
Wydawca:
Instytut Medycyny Wsi
Tematy:
excimer laser
stenosis
atherosclerosis
angioplasty
coronary artery disease
Opis:
Introduction. The technology of laser atherectomy has been known for about 20 years. Initial studies were not encouraging due to similar or lower efficacy compared to conventional angioplasty and greater complication rate. The introduction of new, low-profile catheters with high parameters of transmitted energy, a change in the procedure for performing angioplasty and the proper qualification of the lesions resulted in a reduction of adverse effects. Objective. The aim of the study was to present the current state of knowledge regarding the usage of excimer laser in coronary and peripheral arteries stenosis, its indications and contraindications as well as safety aspect. The article reviews 32 recent publications available on the PubMed and Google Scholar databases. Abbreviated description of the state of knowledge. The excimer laser emits ultraviolet energy and ablates the tissue in a vessel. The main indications for the use of the laser include: restenosis in the stent, ostial lesions, long, calcified lesions >20 mm and moderately and severely calcified lesions. There are isolated reports describing the use of ELCA in the treatment of acute coronary syndromes. Excimer laser also can be applied in a treatment of stenosis of peripheral arteries. Conclusion. Excimer laser coronary atherectomy is a safe and feasible technique for the treatment of ISR and is associated with a relatively low recurrent restenosis compared to scoring balloon dilatation alone. It is a very important and safe alternative to classic treatment methods, but further research assessing the usefulness of this procedure is required.
Źródło:
Journal of Pre-Clinical and Clinical Research; 2020, 14, 4; 145-150
1898-2395
Pojawia się w:
Journal of Pre-Clinical and Clinical Research
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Lyell’s syndrome as a factor which escalates the risk of laryngotracheal stenosis and atresia after intubation
Autorzy:
Nowak, Nel
Kotowski, Michał
Sroczyński, Jakub
Szydłowski, Jarosław
Powiązania:
https://bibliotekanauki.pl/articles/1399653.pdf
Data publikacji:
2019
Wydawca:
Index Copernicus International
Tematy:
Lyell’s Syndrome
subglottic stenosis
intubation
laryngotracheal reconstruction
Opis:
Toxic epidermal necrolysis (TEN) also known as Lyell’s Syndrome is a rare, acute hypersensitivity reaction characterized by cutaneous and mucosal necrosis covering more than 30% of surface [1]. Lyell’s syndrome is self limited, but potentially recurrent disease. The mortality for toxic epidermal necrolysis is approaching to 20–66% [2]. Lyell Syndrome is extremely rare diseases with an estimated overall incidence of 1–2 per 1 million inhabitants per year [3]. TEN is more common in women, it can occur at any age, whereas mostly occurs in older patients in their fifth to seventh decades. Death is caused either by sepsis or by respiratory distress which is either due to pneumoniae or damage to the linings of the airway [4]. Subglottic stenosis is the most common anomaly of larynx and trachea requiring tracheostomy in pediatric population [5]. Subglottic part of larynx is the narrowest section of laryngotracheal area of airways in childhood [5]. It is estimated that most of subglottic stenosis cases is acquired and developed as a result of injury caused by long-term use of endotracheal tube,only 5% of subglottic stenosis is congenital [6]. Latest improvements about construction of endotracheal tube and rules of procedures reduced frequency of subglottic stenosis to less than 1%. There are no statistics or medical reports about tracheal atresia caused by intubation or Lyell’s syndrome. This situation forced us to recognise Lyell’s syndrome and endotracheal intubation overlapping on each other as a cause of medical state of our 2 years old patient.
Źródło:
Polski Przegląd Otorynolaryngologiczny; 2019, 8, 3; 50-54
2084-5308
2300-7338
Pojawia się w:
Polski Przegląd Otorynolaryngologiczny
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Radiation effect on MHD blood flow through a tapered porous stenosed artery with thermal and mass diffusion
Autorzy:
Sharma, M.
Gaur, R. K.
Sharma, B. K.
Powiązania:
https://bibliotekanauki.pl/articles/266195.pdf
Data publikacji:
2019
Wydawca:
Uniwersytet Zielonogórski. Oficyna Wydawnicza
Tematy:
przepływ krwi
reakcja chemiczna
magnetohydrodynamika
Soret and Dufour effects
MHD
blood flow
stenosis
chemical reaction
Opis:
A mathematical model for MHD blood flow through a stenosed artery with Soret and Dufour effects in the presence of thermal radiation has been studied. A uniform magnetic field is applied perpendicular to the porous surface. The governing non-linear partial differential equations have been transformed into linear partial differential equations, which are solved numerically by applying the explicit finite difference method. The numerical results are presented graphically in the form of velocity, temperature and concentration profiles. The effects of various parameters such as the Reynolds number, Hartmann number, radiation parameter, Schmidt number and Prandtl number, Soret and Dufour parameter on the velocity, temperature and concentration have been examined with the help of graphs. The present results have an important bearing on the therapeutic procedure of hyperthermia, particularly in understanding/regulating blood flow and heat transfer in capillaries.
Źródło:
International Journal of Applied Mechanics and Engineering; 2019, 24, 2; 411-423
1734-4492
2353-9003
Pojawia się w:
International Journal of Applied Mechanics and Engineering
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Screening test for extracranial carotid lesions’ detection in patients of an outpatient vascular clinic
Autorzy:
Każmierski, Piotr
Pająk, Michał
Kruś-Hadała, Justyna
Jęckowski, Mateusz
Bogusiak, Katarzyna
Powiązania:
https://bibliotekanauki.pl/articles/1392080.pdf
Data publikacji:
2019
Wydawca:
Index Copernicus International
Tematy:
atherosclerotic lesions
abdominal aorta aneurysm
carotid artery stenosis
screening tool
vascular surgery
Opis:
Purpose The objective of the study was to evaluate the frequency and severity of atherosclerotic lesions in extracranial sections of carotid arteries and to determine the level of the correlation between these lesions and symptoms of cerebral ischemia. Secondly, to identify the most common risk factors of ischaemic stroke occurrence in population of patients of vascular outpatient clinic. Material and Methods Prospective study was conducted on a group of 1,000 people (217 women and 783 men), aged 50 to 86 years, the average age was 62 years (± 9.95). Results Atherosclerotic lesions of carotid arteries were observed in 670 examined people (67%). In 63 cases (6.3%) carotid artery occlusion was revealed. Patients with symptomatic carotid artery stenosis more frequently were addicted to cigarettes and suffered from hypertension in comparison to asymptomatic group. A statistically significant correlation between the TIA or ischemic stroke and smoking were noticed, as well as between TIA/ischemic stroke and hypertension Conclusions Among patients with atherosclerosis of peripheral arteries atherosclerotic lesions in the extracranial carotid sections occur with a high frequency. Statistically significant differences in the incidence and severity of atherosclerotic lesions in the carotid arteries were observed in this group. A statistically significant correlation was revealed between the prevalence and severity of atherosclerosis in the carotid arteries in symptomatic patients and smoking and hypertension. Performing screening in patients with atherosclerosis of the abdominal aorta and/or lower limb arteries may detect significant carotid artery stenosis, requiring surgical intervention.
Źródło:
Polish Journal of Surgery; 2019, 91, 5; 5-11
0032-373X
2299-2847
Pojawia się w:
Polish Journal of Surgery
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Regional resting state perfusion variability and delayed cerebrovascular uniform reactivity in subjects with chronic carotid artery stenosis
Autorzy:
Szarmach, Arkadiusz
Kaszubowski, Mariusz
Sabisz, Agnieszka
Frydrychowski, Andrzej
Halena, Grzegorz
Piskunowicz, Maciej
Dzierzanowski, Jarosław
Studniarek, Michał
Szurowska, Edyta
Winklewski, Pawel
Powiązania:
https://bibliotekanauki.pl/articles/1038538.pdf
Data publikacji:
2018
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
chronic carotid artery stenosis
computed tomography perfusion
acetazolamide test
cerebral blood flow
cerebral blood volume
mean transit time
time to peak
Opis:
The aim of this study was to assess regional perfusion at baseline and regional cerebrovascular resistance (CVR) to delayed acetazolamide challenge in subjects with chronic carotid artery stenosis. Sixteen patients (ten males) aged 70.94±7.71 with carotid artery stenosis ≥ 90% on the ipsilateral side and ≤ 50% on the contralateral side were enrolled into the study. In all patients, two computed tomography perfusion examinations were carried out; the first was performed before acetazolamide administration and the second 60 minutes after injection. The differences between mean values were examined by paired two-sample t-test and alternative nonparametric Wilcoxon's test. Normality assumption was examined using W Shapiro-Wilk test. The lowest resting-state cerebral blood flow (CBF) was observed in white matter (ipsilateral side: 18.4±6.2; contralateral side: 19.3±6.6) and brainstem (ipsilateral side: 27.8±8.5; contralateral side: 29.1±10.8). Grey matter (cerebral cortex) resting state CBF was below the normal value for subjects of this age: frontal lobe - ipsilateral side: 30.4±7.0, contralateral side: 33.7±7.1; parietal lobe - ipsilateral side: 36.4±11.3, contralateral side: 42.7±9.9; temporal lobe - ipsilateral side: 32.5±8.6, contralateral side: 39.4±10.8; occipital lobe - ipsilateral side: 24.0±6.0, contralateral side: 26.4±6.6). The highest resting state CBF was observed in the insula (ipsilateral side: 49.2±17.4; contralateral side: 55.3±18.4). A relatively high resting state CBF was also recorded in the thalamus (ipsilateral side: 39.7±16.9; contralateral side: 41.7±14.1) and cerebellum (ipsilateral side: 41.4±12.2; contralateral side: 38.1±11.3). The highest CVR was observed in temporal lobe cortex (ipsilateral side: +27.1%; contralateral side: +26.1%) and cerebellum (ipsilateral side: +27.0%; contralateral side: +34.6%). The lowest CVR was recorded in brain stem (ipsilateral side: +20.2%; contralateral side: +22.2%) and white matter (ipsilateral side: +18.1%; contralateral side: +18.3%). All CBF values were provided in milliliters of blood per minute per 100 g of brain tissue (ml/100g/min). Resting state circulation in subjects with carotid artery stenosis is low in all analysed structures with the exception of insula and cerebellum. Acetazolamide challenge yields relatively uniform response in both hemispheres in the investigated population. Grey matter is more reactive to acetazolamide challenge than white matter or brainstem.
Źródło:
Acta Biochimica Polonica; 2018, 65, 1; 151-162
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Clinical manifestations of granulomatosis with polyangiitis (GPA) in dermatology and otolaryngology
Autorzy:
Ziuzia, Laura
Dobrzyński, Paweł
Sobolewski, Piotr
Walecka-Herniczek, Irena
Powiązania:
https://bibliotekanauki.pl/articles/1400276.pdf
Data publikacji:
2017
Wydawca:
Index Copernicus International
Tematy:
granulomatosis with polyangitis
head and neck
rhinosinusitis
otitis media
sensineurinal leasing loss
subglottic stenosis
cutaneous changes
ocular changes
oral changes
Opis:
The diseases caused by vasculitis are rare. The difficulties in diagnosis may be due to this low frequency, as well as to rather slow development and various symptoms and locations of the symptoms. In the diagnosis of the vasculitis one should consider all of the clinical features, for they may include diagnostic criteria for various clinical entities.
Źródło:
Polski Przegląd Otorynolaryngologiczny; 2017, 6, 2; 8-14
2084-5308
2300-7338
Pojawia się w:
Polski Przegląd Otorynolaryngologiczny
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Large prospective validation and cultural adaptation of the Polish version of the Swiss Spinal Stenosis Questionnaire for patients with lumbar spinal stenosis
Autorzy:
Tomaszewski, Krzysztof Andrzej
Kłosiński, Michał
Henry, Brandon Michael
Skinningsrud, Bendik
Kucharska, Ewa
Dudkiewicz, Zbigniew
Chrzanowski, Robert
Mikos, Marcin
Głowacki, Roman
Pąchalska, Maria
Powiązania:
https://bibliotekanauki.pl/articles/986690.pdf
Data publikacji:
2017
Wydawca:
Instytut Medycyny Wsi
Tematy:
quality of life
lumbar spinal stenosis
swiss spinal stenosis questionnaire
polish validation study
Opis:
Objective. The aim of this prospective cohort study was to translate, validate and perform a cultural adaptation of the Polish version of the Swiss Spinal Stenosis Questionnaire (P-SSSQ), a disease-specific questionnaire for assessing symptom severity, physical function and satisfaction with treatment in patients with lumbar spinal stenosis (LSS). Materials and method. Patients were prospectively recruited at two orthopedic centres in Krakow, Poland, between January 2011 – October 2016. During the interview, each patient completed the P-SSSQ, SF-36 Health Survey, and a demographic data questionnaire. After translation, cross-cultural adaptation, and pilot testing, assessment was made of the internal consistency, test–retest reliability, construct validity, and responsiveness of the P-SSSQ subscales. Results. Finally, 171 consecutive patients were included in the study. Cronbach’s alpha and ICC values were above 0.8 for all three subscales of the P-SSSQ. The symptom severity domain was highly negatively correlated with physical functioning and bodily pain of SF-36, with Pearson correlation coefficients of -0.68 and -0.63, respectively. The physical function domain was highly negatively correlated with physical functioning (r = -0.62). The satisfaction subscale was also highly negatively correlated with the change in the symptom severity (r = −0.61) and physical function scale (r = −0.65). Conclusions. The proposed version of the P-SSSQ showed excellent measurement properties and can be considered validated for use in Polish. It is easy to understand, quick to complete, and the psychometric properties of the original version are maintained.
Źródło:
Annals of Agricultural and Environmental Medicine; 2017, 24, 4
1232-1966
Pojawia się w:
Annals of Agricultural and Environmental Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Statistical evaluation of the efficiency of the two types of protection systems in carotid artery stenting
Statistické vyhodnocení účinnosti dvou typů protekčních zařízení při karotickém stentingu
Autorzy:
Rabasová, M.
Pavlík, O.
Powiązania:
https://bibliotekanauki.pl/articles/113305.pdf
Data publikacji:
2017
Wydawca:
STE GROUP
Tematy:
carotid stenosis
embolic protection devices
statistical tests
Mann-Whitney test
χ2 test
Arcsine test
zwężenie tętnicy szyjnej
urządzenie chroniące przed zatorami
testy statystyczne
test Manna-Whitneya
test χ2
test Arcsine
Opis:
The article deals with the evaluation of the efficiency of the two types of protection systems in carotid artery stenting (CAS). Carotid artery stenting is a treatment of carotid artery stenosis, which is a narrowing of the carotid artery caused by a plaque buildup in the artery wall. Pieces of plaque can break off and block the blood flow in the artery, which leads to a stroke. Carotid artery stenting is an endovascular surgery where a stent is deployed within the lumen of the affected carotid artery to dilate it and prevent a stroke. Two types of embolic protection devices are commonly used during CAS - distal protection devices (filters) and proximal protection devices. The aim of this study was to determine whether the two protection systems differ in the number and in the location of new ischemic lesions after surgery. Statistical analysis was carried out with the programs SPSS and Microsoft Excel. Mann-Whitney test, χ2 test and Arcsine test were used and the value of p = 0.05 was taken as a level of significance.
Tento článek pojednává o vyhodnocení účinnosti dvou protekčních systémů používaných při karotickém stentingu (CAS). Karotický stenting je léčba karotické stenózy, což je zúžení karotické tepny způsobené plakem usazeným na cévní stěně. Kousky plaku se mohou uvolnit a zablokovat průchod krve, což může způsobit mozkovou mrtvici. Karotický stenting je endovaskulární chirurgická metoda, při které se do postižené tepny zavede stent, který má tepnu roztáhnout a zabranit tak mrtvici. V průběhu CAS jsou běžně používány dva typy protekčních zařízení - distální protekční zařízení (filtry) a proximální protekční zařízení. Cílem této studie bylo zjistit, zda se tyto dva protekční systémy liší v počtu a v lokalizaci nových ischemických lézí po operaci. K statistické analýze byly použity MannůvWhitneyův test, χ2 test a arcsinový test (s hladinou významnosti p = 0,05), výpočty byly provedeny pomocí programů SPSS a Microsoft Excel.
Źródło:
Systemy Wspomagania w Inżynierii Produkcji; 2017, 6, 4; 215-221
2391-9361
Pojawia się w:
Systemy Wspomagania w Inżynierii Produkcji
Dostawca treści:
Biblioteka Nauki
Artykuł
Wyświetlanie 1-15 z 33

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