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Wyświetlanie 1-15 z 72
Tytuł:
Improved cut flower and corm production by exogenous moringa leaf extract application on gladiolus cultivars
Autorzy:
Younis, A.
Akhtar, M.S.
Riaz, A.
Zulfiqar, F.
Qasim, M.
Farooq, A.
Tariq, U.
Ahsan, M.
Bhatti, Z.M.
Powiązania:
https://bibliotekanauki.pl/articles/11855333.pdf
Data publikacji:
2018
Wydawca:
Uniwersytet Przyrodniczy w Lublinie. Wydawnictwo Uniwersytetu Przyrodniczego w Lublinie
Tematy:
Pakistan
Faisalabad city
ornamental plant
Gladiolus
Gladiolus grandiflorus
Rose Supreme cultivar
White Prosperity cultivar
cut flower
corm
corm size
spike length
vase life
growth regulator
Moringa oleifera
leaf extract
climate condition
Opis:
Bio-stimulants are in excessive demand for the sustainable production of floriculture crops. The current investigation was designed to find out the effect of naturally occurring growth stimulant moringa leaf extract (MLE) on the growth, flowering, post-harvest life and corm production of two gladiolus cultivars (cvs.) ‘Rose Supreme’ and ‘White Prosperity’. The research trial was laid out in the factorial arrangement under randomized complete block design. Corms were grown in the open field under local climatic conditions of Faisalabad, Pakistan. Potential of exogenously applied (MLE; 30 times diluted) was evaluated. Treatments including spraying MLE at 3 leaves, 5 leaves, floral bud stage, one combination of these three stages relative to control with no foliar application. Application of natural bio-stimulant produced maximum height in both cvs. against T4. Both cvs. gave maximum stalk length in response to T4. The number of florets spike–1 found the maximum (13) in T1 compared to control T0 which yield (9) florets. Maximum vase life in sucrose solution (13.33 days) was exhibited by T1 for both cvs. while minimum (10 days) in T0. In cultivar comparison earlier spike emergence was observed in ‘White Prosperity’. In ‘Rose Supreme’ maximum corm weight was attained in response to T3 (43.43 g) while minimum (30.33 g) in T0.‘White Prosperity’ produced maximum weight (40.33 g) against T4 whereas minimum by control. The cultivar mean comparison showed the superiority of cormel diameter in ‘Rose Supreme’ (10.93 mm) than ‘White Prosperity’ (9.13 mm). In treatment comparison, T4 produced maximum diameter (12.04 mm) in ‘Rose Supreme’ moreover, T2 induced maximum (9.57 mm) diameter in ‘White Prosperity’.
Źródło:
Acta Scientiarum Polonorum. Hortorum Cultus; 2018, 17, 4; 25-38
1644-0692
Pojawia się w:
Acta Scientiarum Polonorum. Hortorum Cultus
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Coronaviruses fusion with the membrane and entry to the host cell
Autorzy:
Wędrowska, E.
Wandtke, T.
Senderek, T.
Piskorska, E.
Kopiński, P.
Powiązania:
https://bibliotekanauki.pl/articles/2085559.pdf
Data publikacji:
2020
Wydawca:
Instytut Medycyny Wsi
Tematy:
coronavirus
spike protein
membrane fusion
viral entry
nonstructural proteins
replication complex
Opis:
Introduction. Coronaviruses (CoVs) are positive-strand RNA viruses with the largest genome among all RNA viruses. They are able to infect many host, such as mammals or birds. Whereas CoVs were identified 1930s, they became known again in 2003 as the agents of the Severe Acute Respiratory Syndrome (SARS). The spike protein is thought to be essential in the process of CoVs entry, because it is associated with the binding to the receptor on the host cell. It is also involved in cell tropism and pathogenesis. Receptor recognition is the crucial step in the infection. CoVs are able to bind a variety of receptors, although the selection of receptor remains unclear. Coronaviruses were initially believed to enter cells by fusion with the plasma membrane. Further studies demonstrated that many of them involve endocytosis through clathrin-dependent, caveolae-dependent, clathrin-independent, as well as caveolae-independent mechanisms. Objectives. The aim of this review is to summarise current knowledge about coronaviruses, focussing especially on CoVs entry into the host cell. Advances in understanding coronaviruses replication strategy and the functioning of the replicative structures are also highlighted. The development of host-directed antiviral therapy seems to be a promising way to treat infections with SARS-CoV or other pathogenic coronaviruses. There is still much to be discovered in the inventory of pro-and anti-viral host factors relevant for CoVs replication. The latest pandemic danger, originating from China, has given our previously prepared work even more of topicality.
Źródło:
Annals of Agricultural and Environmental Medicine; 2020, 27, 2; 175-183
1232-1966
Pojawia się w:
Annals of Agricultural and Environmental Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Towards spike-based speech processing: a biologically plausible approach to simple acoustic classification
Autorzy:
Uysal, I.
Sathyendra, H.
Harris, J. G.
Powiązania:
https://bibliotekanauki.pl/articles/907947.pdf
Data publikacji:
2008
Wydawca:
Uniwersytet Zielonogórski. Oficyna Wydawnicza
Tematy:
kodowanie synchroniczne
blokowanie fazowe
percepcja mowy
psychoakustyka
rozpoznawanie mowy
spike coding
synchrony coding
phase locking
speech perception
psychoacoustics
speech recognition
Opis:
Shortcomings of automatic speech recognition (ASR) applications are becoming more evident as they are more widely used in real life. The inherent non-stationarity associated with the timing of speech signals as well as the dynamical changes in the environment make the ensuing analysis and recognition extremely difficult. Researchers often turn to biology seeking clues to make better engineered systems, and ASR is no exception with the usage of feature sets such as Mel frequency cepstral coefficients, which employ filter banks similar to cochlear filter banks in frequency distribution and bandwidth. In this paper, we delve deeper into the mechanics of the human auditory system to take this biological inspiration to the next level. The main goal of this research is to investigate the computation potential of spike trains produced at the early stages of the auditory system for a simple acoustic classification task. First, various spike coding schemes from temporal to rate coding are explored, together with various spike-based encoders with various simplicity levels such as rank order coding and liquid state machine. Based on these findings, a biologically plausible system architecture is proposed for the recognition of phonetically simple acoustic signals which makes exclusive use of spikes for computation. The performance tests show superior performance on a noisy vowel data set when compared with a conventional ASR system.
Źródło:
International Journal of Applied Mathematics and Computer Science; 2008, 18, 2; 129-137
1641-876X
2083-8492
Pojawia się w:
International Journal of Applied Mathematics and Computer Science
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Molecular docking studies on the phytoconstituents as therapeutic leads against SARS-CoV-2
Molekularne badania dokujące nad zastosowaniem fitoskładników w terapii przeciw SARS-CoV-2
Autorzy:
Tiwari, Abhishek
Tiwari, Varsha
Verma, Navneet
Singh, Anita
Kumar, Manish
Saini, Vipin
Sahoo, Biswa Mohan
Kaushik, Deepak
Verma, Ravinder
Sagadevan, Suresh
Powiązania:
https://bibliotekanauki.pl/articles/2202611.pdf
Data publikacji:
2022
Wydawca:
Sieć Badawcza Łukasiewicz - Instytut Chemii Przemysłowej
Tematy:
Covid-19
spike glycoprotein
AutoDock Vina
Mpro
docking
artemisinin
withaferin A
glikoproteina kolca
dokowanie
artemizynina
witaferyna A
Opis:
Because of the present pandemic researchers are seeking for phytocandidates that can inhibit or stop SARS-CoV-2. The main protease (Mpro) of SARS-CoV-2 and spike glycoprotein (S) are both suppressed by bioactive compounds found in plants that work by docking them together. The Mpro proteins 6LU7 (complex with an inhibitor N3) and 5C3N (space group C2221) were employed in docking research. PyRx and AutoDock Vina software were used as docking engine. 22 identified phytoconstituents were selected from IMPPAT, a manually curated database, on the basis of their antiviral effects. Docking studies showed that phytoconstituents β-amyrin (-8.4 kcal/mol), withaferin A (-8.3 kcal/mol), oleanolic acid (-7.8 kcal/mol), and patentiflorin A (-8.1 kcal/mol) had the best results against 5C3N Mpro protein whereas kuwanon L (-7.1 kcal/mol), β-amyrin (-6.9 kcal/mol), oleanolic acid (-6.8 kcal/mol), cucurbitacin D (-6.5 kcal/mol), and quercetin (-6.5 kcal/mol) against 6LU7 Mpro protein. All the compounds were examined for their ADMET characteristics using SwissDock. Present research reports that the phytoconstituents along with docking score will be helpful for future drug development against Covid-19.
W związku z pandemią prowadzone są badania mające na celu znalezienie fitosubstancji, które mogą hamować lub zatrzymywać rozwój SARS-CoV-2. Działanie głównych białek proteazy (Mpro) SARS-CoV-2 i glikoproteiny kolca (S) jest osłabiane przez związki bioaktywne występujące w roślinach poprzez proces dokowania. Do badań dokujących użyto białka Mpro 6LU7 (kompleks z inhibitorem N3) i 5C3N (grupa przestrzenna C2221). Jako silnik dokujący zastosowano PyRx i AutoDock Vina. Zidentyfikowano 22 fitoskładniki wybrane z bazy danych IMPPAT, z uwzględnieniem ich działania przeciwwirusowego. Najbardziej skuteczne w przypadku białka Mpro 5C3N okazały się fitoskładniki β-amyryna (-8,4 kcal/mol), witaferyna A (-8,3 kcal/mol), kwas oleanolowy (-7,8 kcal/mol) i patentifloryna A (-8,1 kcal/mol), a w przypadku białka Mpro 6LU7 kuwanon L (-7,1 kcal/mol), β-amyryna (-6,9 kcal/mol), kwas oleanolowy (-6,8 kcal/mol), kukurbitacyna D (-6,5 kcal/mol) i kwercetyna (-6,5 kcal/mol). Wszystkie substancje zbadano pod kątem ich właściwości ADMET przy użyciu SwissDock. Wykazano, że fitoskładniki mogą być pomocne w pracach nad lekami przeciwko Covid-19.
Źródło:
Polimery; 2022, 67, 7-8; 355---374
0032-2725
Pojawia się w:
Polimery
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Kernel analysis for estimating the connectivity of a network with event sequences
Autorzy:
Tezuka, T.
Claramunt, C.
Powiązania:
https://bibliotekanauki.pl/articles/91880.pdf
Data publikacji:
2017
Wydawca:
Społeczna Akademia Nauk w Łodzi. Polskie Towarzystwo Sieci Neuronowych
Tematy:
connectivity estimation
neural network
kernel methods
spike train
Opis:
Estimating the connectivity of a network from events observed at each node has many applications. One prominent example is found in neuroscience, where spike trains (sequences of action potentials) are observed at each neuron, but the way in which these neurons are connected is unknown. This paper introduces a novel method for estimating connections between nodes using a similarity measure between sequences of event times. Specifically, a normalized positive definite kernel defined on spike trains was used. The proposed method was evaluated using synthetic and real data, by comparing with methods using transfer entropy and the Victor-Purpura distance. Synthetic data was generated using CERM (Coupled Escape-Rate Model), a model that generates various spike trains. Real data recorded from the visual cortex of an anaesthetized cat was analyzed as well. The results showed that the proposed method provides an effective way of estimating the connectivity of a network when the time sequences of events are the only available information.
Źródło:
Journal of Artificial Intelligence and Soft Computing Research; 2017, 7, 1; 17-31
2083-2567
2449-6499
Pojawia się w:
Journal of Artificial Intelligence and Soft Computing Research
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Multiple spike stall cells in low speed axial compressor rotor blade row
Autorzy:
Taghavi-Zenouz, R
Abbasi, S.
Powiązania:
https://bibliotekanauki.pl/articles/279770.pdf
Data publikacji:
2015
Wydawca:
Polskie Towarzystwo Mechaniki Teoretycznej i Stosowanej
Tematy:
axial compressor
spike stall inception
tip leakage flow
frequency spectrum
Opis:
Inception and development of multiple stall cells of short length scales are numerically investigated in an axial compressor rotor blade row. The method of investigation is based on time accurate three-dimensional full annulus simulations. Time dependent flow structure results revealed that there are two criteria responsible for inception of a special kind of stall, introduced as spike stall in the literature. These criteria are defined as leading edge spillage and trailing edge backflow, which occur at specific mass flow rates near to stall conditions. The numerical results revealed that once the spike stall cells appear, they cover roughly two blade passages in the circumferential direction and cover about 25% of the blade height. By further revolution of the blade row, the number of cells tends to increase. For the present case study, the number of stall cells increased to three after 8.5 rotor revolutions from the moment of the initial spike stall occurrence. Even at this moment, both of the above mentioned criteria for the spike stall inception have been observed within the blades passages. These events caused the inlet relative flow angle to the blade rows, and therefore the flow incidence angle and consequent blockage to the main flow, to increase. The tip leakage flow frequency spectrum has been studied through surveying instantaneous static pressure signals imposed on pressure side of the blades and also on the casing walls. These latter results showed that any further revolving of the rotor blade row, exceeding 8.5 revolutions, causes the spike stall to disturb the flow structure significantly.
Źródło:
Journal of Theoretical and Applied Mechanics; 2015, 53, 1; 47-57
1429-2955
Pojawia się w:
Journal of Theoretical and Applied Mechanics
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Being John Malkovich and the Philosophy of Cyberspace Addiction
Autorzy:
Szczypa, Piotr
Powiązania:
https://bibliotekanauki.pl/articles/1804549.pdf
Data publikacji:
2019-10-24
Wydawca:
Katolicki Uniwersytet Lubelski Jana Pawła II. Towarzystwo Naukowe KUL
Tematy:
cyberprzestrzeń; uzależnienie od cyberprzestrzeni; cyberkultura; Spike Jonze; film; Być jak John Malkovich
cyberspace; cyberspace addiction; cyberculture; Spike Jonze; film; Being John Malkovich
Opis:
Być jak John Malkovich i filozofia uzależnienia od cyberprzestrzeni Niniejszy artykuł omawia możliwy przykład symbolicznej interakcji cyberprzestrzeni z przestrzenią rzeczywistą. Jego tematem jest analiza fabuły filmu Spike’a Jonze’a Być jak John Malkovich (oryg. Being John Malkovich) z 1999 roku, a przedstawiona teza dotyczy możliwości interpretacji filmu jako filozoficznej alegorii uzależnienia od cyberprzestrzeni. Analiza filmu skupia się na jego głównych bohaterach oraz różnych formach ich relacji z tytułowym Johnem Malkovichem, który stanowi w filmie uosobienie cyberprzestrzeni.
The present article discusses a possible instance of a symbolic interaction between cyberspace and real-life space, analysing the plot of Spike Jonze’s 1999 film Being John Malkovich, and arguing that it may be interpreted as a philosophical account of an addiction to cyberspace. The analysis focuses on the main characters of the film, discussing various forms of their relationship to John Malkovich, who, as it is claimed, personifies cyberspace in the film.
Źródło:
Roczniki Humanistyczne; 2018, 66, 11; 165-180
0035-7707
Pojawia się w:
Roczniki Humanistyczne
Dostawca treści:
Biblioteka Nauki
Artykuł
Wyświetlanie 1-15 z 72

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