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Tytuł:
Complications of radio- and radiochemotherapy in patients undergoing major salivary gland cancer surgery
Autorzy:
Kordzińska-Cisek, Izabela
Grzybowska-Szatkowska, Ludmiła
Powiązania:
https://bibliotekanauki.pl/articles/1397794.pdf
Data publikacji:
2019
Wydawca:
Index Copernicus International
Tematy:
salivary gland tumours
radiotherapy
radiochemotherapy
radiation-induced reaction
Opis:
Purpose: The aim of this retrospective study was to present the prevalence of early and late radiation-induced reaction and factors affecting its formation and severity in patients after adjuvant radio- or radiochemotherapy in salivary gland cancer. Material and methods: A total of 113 patients with early and 91 with late radiation-induced reaction, irradiated in 2006-2016 were enrolled in the study. The frequency of acute mucosal radiation-induced reaction, time of onset, intensity, healing time, as well as the incidence of late radiation-induced reaction from the skin and subcutaneous tissue were analyzed. Factors that could influence the development and intensity of reaction were identified. Results: Acute severity and the presence of late radiation-induced reaction do not affect overall survival. Dosage in the tumor bed site, as well as the dosage in the nodal region, affect the severity of the acute radiation-induced mucosal reaction. The severity of the early radiation-induced reaction is higher in men, more advanced patients (higher T and N+ in TNM classification), irradiated into a larger area, and those in whom two-dimensional planning and complementary chemoradiotherapy were applied. The late reaction of the skin and subcutaneous tissue was dominated by patients irradiated in the nodal regions and those with a higher intensity of early radiation-induced reaction. Conclusions: Supplementary radiotherapy or radiochemotherapy in salivary gland cancer is associated with acceptable toxicity which has no effect on overall survival.
Źródło:
Polish Journal of Otolaryngology; 2019, 73, 3; 26-31
0030-6657
2300-8423
Pojawia się w:
Polish Journal of Otolaryngology
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
First bite syndrome: the complication to keep in mind
Zespół pierwszego ugryzienia: powikłanie o którym warto pamiętać
Autorzy:
Tretiakow, Dmitry
Skorek, Andrzej
Powiązania:
https://bibliotekanauki.pl/articles/1399689.pdf
Data publikacji:
2019-10-25
Wydawca:
Index Copernicus International
Tematy:
headache
infratemporal fossa
painful bite
parapharyngeal space
parotidectomy
postoperative complication
salivary gland tumor
bolesne ugryzienie
ból głowy
dół podskroniowy
guz ślinianki
parotidektomia
powikłanie pooperacyjne
przestrzeń przygardłowa
Opis:
The First Bite Syndrome is a rare late (1-2 months) post operation complication of surgery in the infratemporal fossa, parapharyngeal space and especially involving the deep lobe of parotid gland. Sometimes it can significantly worsen the patient's quality of life. Acute, sudden, short time pain in the parotid gland region with irradiation to the ear during the first bite a meal is a characteristic for this syndrome. The correct diagnosis and individual approach in choosing a treatment method is the key to success in treating this complication. The purpose of our article is to supplement scanty data on this complication in Polish literature.
Zespół pierwszego ugryzienia jest rzadkim powikłaniem występującym w późnym okresie po interwencji chirurgicznej (1-2 miesiące) w dole podskroniowym, przestrzeni przygardłowej oraz szczególnie okolicach głębokiego płata ślinianki przyusznej. Może on jednak istotnie pogorszyć jakość życia pacjenta. Ostry, nagły ból w okolicy ślinianki przyusznej z promieniowaniem do ucha w trakcie pierwszego ugryzienia podczas spożywania posiłku jest charakterystycznym objawem tego zespołu. Prawidłowe jego rozpoznanie oraz indywidualne podejście w wyborze metody leczenia jest kluczem do sukcesu w leczeniu tego powikłania. Celem naszego artykułu jest uzupełnienie skąpych danych na temat tego powikłania w piśmiennictwie polskim.
Źródło:
Polski Przegląd Otorynolaryngologiczny; 2019, 8, 4; 1-3
2084-5308
2300-7338
Pojawia się w:
Polski Przegląd Otorynolaryngologiczny
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Head and neck amyloidosis – a report on five cases
Amyloidoza w rejonie głowy i szyi – opis serii przypadków
Autorzy:
Orłowska, Anna
Mastalerek, Jan
Jaskólska, Magdalena
Rzepakowska, Anna
Grzybowski, Jakub
Gotlib, Tomasz
Niemczyk, Kazimierz
Powiązania:
https://bibliotekanauki.pl/articles/1399353.pdf
Data publikacji:
2020
Wydawca:
Index Copernicus International
Tematy:
amyloidosis
amyloidosis of the nasopharynx
head and neck amyloidosis
larynx amyloidosis
localized amyloidosis
salivary gland amyloidosis
tongue amyloidosis
amyloidoza
amyloidoza głowy i szyi
amyloidoza języka
amyloidoza krtani
amyloidoza miejscowa
amyloidoza nosogardła
amyloidoza ślinianek
Opis:
Background: Amyloidosis is a group of diseases caused by the extracellular accumulation of insoluble fibers called amyloid in the tissues and organs. They have a secondary beta-sheet structure, which makes them resistant to proteolysis. In histological examination amyloid deposits stain with Congo red and show an apple-green birefringence in polarized light. Amyloid deposits disturb the function of organs and cause clinical symptoms. Their formation or accumulation in the system may be acquired or inherited. Due to the location of amyloid deposits we distinguish systemic and localized amyloidosis with the formation of tumors (usually from light chains). Case reports: 5 cases of amyloidosis in the head and neck region are presented in this paper. The locations of the amyloid deposits were as follows: larynx, nasopharynx, sublingual and submandibular gland and the tongue. The initial clinical presentation correlated with location of amyloid tumour in our patients. Two patients had history of local recurrence of the disease. Surgical resection and histopathological examination were performed. Sections stained with Congo red confirmed the diagnosis of amyloidosis. Three patients had potential conditions predisposing to amyloidosis: previous radiotherapy, chronic inflammation due to hepatitis C virus infection and graft versus host disease. Conclusion: Amyloidosis should be considered as the cause of symptoms in pathologies of the head and neck region. The diagnosis requires a histopathological examination. The systemic form of the disease must be ruled out in all patients with head and neck amyloidosis. In localized amyloidosis the surgical resection of the lesions is the procedure of choice, however the organ’s functionality should be taken into account.
Podstawy naukowe: Amyloidoza, czyli skrobawica, to grupa chorób, których wspólną cechą jest pozakomórkowe gromadzenie się w tkankach i narządach nierozpuszczalnych białek o budowie włókienkowej, zwanych amyloidem. Mają one drugorzędową strukturę β-kartki, co czyni je opornymi na proteolizę. W skrawkach histologicznych złogi amyloidu wybarwiają się czerwienią Kongo i wykazują zielone świecenie w świetle spolaryzowanym. Depozyty amyloidu zaburzają funkcje narządów i powodują objawy kliniczne. Ich powstawanie lub gromadzenie się w ustroju może być stanem nabytym lub dziedzicznym. Ze względu na lokalizację złogów amyloidu rozróżniamy: (1) amyloidozę układową, czyli uogólnioną, oraz (2) miejscową z tworzeniem guzów (najczęściej z łańcuchów lekkich immunoglobulin). Opisy przypadków: W niniejszej pracy opisano 5 przypadków amyloidozy w regionie głowy i szyi. Zmiany zlokalizowane były w obrębie: krtani, nosogardła, ślinianki podjęzykowej i podżuchwowej oraz języka. Pacjenci zgłaszali objawy typowe dla procesu rozrostowego obejmującego wymienione narządy. U dwóch osób choroba miała charakter nawrotowy. Zmiany usunięto operacyjnie. Na podstawie badania histopatologicznego pobranych tkanek i charakterystycznego barwienie czerwienią Kongo i Saturna, rozpoznano obecność złogów amyloidu. U trzech pacjentów występowały stany predysponujące do wystąpienia amyloidozy: uprzednia radioterapia, przewlekły stan zapalny związany z zakażeniem wirusem zapalenia wątroby typu C i choroba przeszczep przeciwko gospodarzowi. U chorego z makroglosją rozpoznano postać uogólnioną amyloidozy. Podsumowanie: Amyloidoza może imitować objawy zmian rozrostowych w rejonie głowy i szyi. Jej rozpoznanie wymaga badania histopatologicznego. U każdego chorego z miejscową amyloidozą musi zostać wykluczona postać uogólniona. W przypadku postaci miejscowej, resekcja chirurgiczna zmian jest postępowaniem z wyboru. Należy wziąć pod uwagę zachowanie funkcjonalności narządu.
Źródło:
Polski Przegląd Otorynolaryngologiczny; 2019, 8, 2; 32-37
2084-5308
2300-7338
Pojawia się w:
Polski Przegląd Otorynolaryngologiczny
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Hyalinising clear cell carcinoma of salivary gland: a case report
Autorzy:
Osuchowski, Michał
Bartusik-Aebisher, Dorota
Kaznowska, Ewa
Aebisher, David
Powiązania:
https://bibliotekanauki.pl/articles/2037686.pdf
Data publikacji:
2020-06-30
Wydawca:
Uniwersytet Rzeszowski. Wydawnictwo Uniwersytetu Rzeszowskiego
Tematy:
cancer
hyalinising clear cell carcinoma salivary gland
Opis:
Introduction. Clear cell carcinoma, not otherwise specified/hyalinising clear cell carcinoma of the salivary gland (HCCC) is a malignancy that arises in minor salivary glands. It rarely leads to distant metastases or cancer-related death but has the potential for recurrence and focal metastases. Aim. A case is reported. Description of the case. A 72 years old female patient has reported to the Clinic of Otolaryngology with a tongue lesion. The patient had no history of malignancy. The lymph node has been surgically removed for further examination. Cords and nests of clear cells and cells with eosinophilic cytoplasm in a hyalinized stroma were identified within the lymph node. After the diagnosis the patient has been transferred to another Oncology Hospital for further treatment. Conclusion. The diagnosis of clear cell carcinoma may be challenging because many of it‘s features frequently overlap with other salivary gland lesions.
Źródło:
European Journal of Clinical and Experimental Medicine; 2020, 2; 127-130
2544-2406
2544-1361
Pojawia się w:
European Journal of Clinical and Experimental Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Malignant transformation of the salivary gland pleomorphic adenoma in myoepithelial carcinoma – the report of two cases
Autorzy:
Szabelska, Paulina
Rzepakowska, Anna
Szczepankiewicz, Benedykt
Niemczyk, Elżbieta
Osuch-Wójcikiewicz, Ewa
Niemczyk, Kazimierz
Powiązania:
https://bibliotekanauki.pl/articles/1399613.pdf
Data publikacji:
2019
Wydawca:
Index Copernicus International
Tematy:
salivary gland tumors
carcinoma ex pleomorphic adenoma
pleomorphic adenoma
myoepithelial carcinoma
Opis:
A multiform adenoma is the most commonly diagnosed benign tumor of the salivary glands. In the majority of patients, surgical resection of the tumor with the adequate surrounding tissue of salivary gland allows for complete recovery. A small percentage of the cases is a recurring pleomorphic adenoma. Even more rarely the diagnosis of carcinoma ex pleomorphic adenoma is made. The study presents two clinical cases of the malignant transformation of pleomorphic adenoma into the myoepithelial carcinoma. The surgical treatment and additional radiotherapy were performed in both cases.
Źródło:
Polski Przegląd Otorynolaryngologiczny; 2019, 8, 1; 53-58
2084-5308
2300-7338
Pojawia się w:
Polski Przegląd Otorynolaryngologiczny
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Metastasis of clear cell renal cell carcinoma to the organs of the head and neck – an ongoing problem
Autorzy:
Torchalla, Patrycja
Czesak, Małgorzata
Osuch-Wójcikiewicz, Ewa
Powiązania:
https://bibliotekanauki.pl/articles/1398949.pdf
Data publikacji:
2021
Wydawca:
Index Copernicus International
Tematy:
clear cell renal cancer
renal cell carcinoma
metastases
submandibular salivary gland
Opis:
Renal cell carcinoma accounts for about 2-3% of all malignancies. It is characterized by a high frequency of metastases, which are most often observed in the lungs, bones, liver, brain and regional lymph nodes. Literature highlights the rare occurrence of renal cancer metastases to the head and neck, even though it is the third most common cancer that metastasizes to the head and neck. Below we present a case report of metastases of clear cell carcinoma from a kidney to the organs of the head and neck. The analysis was carried out retrospectively based on medical records of a patient hospitalized at the Department of Otorhinolaryngology, Head and Neck Surgery of the Medical University of Warsaw in the years 2009-2019. We describe an 81-year-old man after left-sided nephrectomy due to clear cell carcinoma, with numerous distant metastases, who was diagnosed with metastases to the left submandibular salivary gland 8 years after primary surgery, followed by a diagnosis of metastasis to the right submandibular salivary gland 3 years later. The patient underwent 2 radical procedures to remove the submandibular salivary glands. Due to the presence of lung metastases, treatment with a tyrosine kinase inhibitor was also implemented.
Źródło:
Polski Przegląd Otorynolaryngologiczny; 2021, 10, 1; 42-48
2084-5308
2300-7338
Pojawia się w:
Polski Przegląd Otorynolaryngologiczny
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Mobile phone use and risk for intracranial tumors and salivary gland tumors – A meta-analysis
Autorzy:
Bortkiewicz, Alicja
Gadzicka, Elżbieta
Szymczak, Wiesław
Powiązania:
https://bibliotekanauki.pl/articles/2161927.pdf
Data publikacji:
2017-02-21
Wydawca:
Instytut Medycyny Pracy im. prof. dra Jerzego Nofera w Łodzi
Tematy:
electromagnetic fields
brain tumors
acoustic neuroma
salivary gland tumors
cellular phone
case-control Studies
Opis:
Results of epidemiological studies on the association between use of mobile phone and brain cancer are ambiguous, as well as the results of 5 meta-analysis studies published to date. Since the last meta-analysis (2009), new case-control studies have been published, which theoretically could affect the conclusions on this relationship. Therefore, we decided to perform a new meta-analysis. We conducted a systematic review of multiple electronic data bases for relevant publications. The inclusion criteria were: original papers, case-control studies, published till the end of March 2014, measures of association (point estimates as odds ratio and confidence interval of the effect measured), data on individual exposure. Twenty four studies (26 846 cases, 50 013 controls) were included into the meta-analysis. A significantly higher risk of an intracranial tumor (all types) was noted for the period of mobile phone use over 10 years (odds ratio (OR) = 1.324, 95% confidence interval (CI): 1.028–1.704), and for the ipsilateral location (OR = 1.249, 95% CI: 1.022–1.526). The results support the hypothesis that long-term use of mobile phone increases risk of intracranial tumors, especially in the case of ipsilateral exposure. Further studies are needed to confirm this relationship. Int J Occup Med Environ Health 2017;30(1):27–43
Źródło:
International Journal of Occupational Medicine and Environmental Health; 2017, 30, 1; 27-43
1232-1087
1896-494X
Pojawia się w:
International Journal of Occupational Medicine and Environmental Health
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Neurological complications and quality of life after submandibular gland resection. A Prospective, non-randomized, single-centre study
Autorzy:
Chiesa Estomba, Carlos
Valldeperes-Vilanova, Ariadna
González-García, Jose
Larruscain-Sarasola, Ekhiñe
Sistiaga-Suarez, Jon
Altuna-Mariezcurrena, Xabier
Powiązania:
https://bibliotekanauki.pl/articles/1397732.pdf
Data publikacji:
2019
Wydawca:
Index Copernicus International
Tematy:
neurological complications
salivary gland
submandibular gland
surgery
Opis:
Introduction: There are different complications related to the submandibular gland resection, like damage to the mandibular branch of the facial nerve, lingual or hypoglossal nerve. Moreover, subjective complaints like dry mouth, altered sensation around the scar and taste alterations were described. Patients and methods: A prospective, non-randomized study was performed including 20 patients treated with submandibular gland resection. Results: The most common etiology was sialolithiasis affecting 9 (45%) patients. One (5%) patient presented a lingual nerve paresis, 2 (10%) patients presented a transient marginal mandibular branch paresis and no hypoglossal nerve alteration was observed. Factors like the size of the lithiasis (P = 0.293), size of the tumor (P = 0.445) or type of pathology (P = 0.694) were not related with neurological complications. Altered sensation in the skin around a scar was the most severely weighted problem (55% and 33.3%), and xerostomia was the second one (33% and 27.3%) at one month and at six months after surgery, respectively. Conclusion: The submandibular gland resection remains to be a safe technique with a low rate of surgical and neurological complications. However, patients should be informed about sequelae like xerostomia, altered sensation in the skin or pain around the scar, which may be discomforting. The cosmetic result can be satisfactory, but a surgical scar can be avoided with another approach. Although rare, the risk of MBFN, lingual and hypoglossal nerve damage should always be included in the preoperative information on surgical risks.
Źródło:
Polish Journal of Otolaryngology; 2019, 73, 6; 32-37
0030-6657
2300-8423
Pojawia się w:
Polish Journal of Otolaryngology
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Parotid gland tumors in Northern Greece: a 7-year retrospective study of 207 patients
Autorzy:
Poutoglidis, Alexandros
Tsetsos, Nikolaos
Sotiroudi, Sotiria
Fyrmpas, Georgios
Poutoglidou, Frideriki
Vlachtsis, Konstantinos
Powiązania:
https://bibliotekanauki.pl/articles/23203217.pdf
Data publikacji:
2020-12-10
Wydawca:
Index Copernicus International
Tematy:
cancer
epidemiology
parotid gland
salivary gland
tumor
Opis:
Introduction: Parotid gland neoplasms represent a heterogenous group of tumors, either benign or malignant. The diagnosis and management of parotid gland tumors is complicated by their relative infrequency and their diverse biologic behavior. Aim: The aim of this study is to investigate the epidemiological characteristics, the recurrence rates and the surgical approach employed for parotid gland tumors in Northern Greece. Material and methods: This is a single-center retrospective study. All patients admitted to the ENT department of “G. Papanikolaou” General Hospital of Thessaloniki from January 2012 to June 2019 with the diagnosis of parotid gland tumor were included in the study. Patients with incomplete charts and patients that underwent revision surgeries were excluded. Chi-squared tests were used to assess the associations between variables. Results: A total of 207 patients with a mean age of 54.97 (range 16–91) were included in the study. Benign neoplasms accounted for 87.9% of the cases. Warthin’s tumor was the most common neoplasm encountered, with an incidence of 46.8%, followed by pleomorphic adenoma (31.9%). There was a higher incidence of parotid gland tumors in males and smokers (P = 0.025, P = 0.001 respectively). The majority of the patients were treated with an extracapsular resection (60.4%) or with a partial superficial parotidectomy (22.6%). In 12 cases (5.7%), there was a recurrence of the lesion. The most common complications encountered were facial nerve injury, Frey’s syndrome and hematoma formation. Conclusions: Parotid gland tumors are typically benign, non-aggressive tumors, more frequently seen in men than women. There is a positive association between smoking and parotid gland tumor development. Comprehensive information regarding recurrence and complication rates is presented.
Źródło:
Polish Journal of Otolaryngology; 2021, 75, 5; 39-43
0030-6657
2300-8423
Pojawia się w:
Polish Journal of Otolaryngology
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Plummer Vinson Syndrome (PVS) with parotid gland squamous cell carcinoma in a young female
Autorzy:
Prasada, Swamy T.
Prasad, Vangala Bramha
Srividya, Lonkala
Powiązania:
https://bibliotekanauki.pl/articles/1112557.pdf
Data publikacji:
2018
Wydawca:
Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
Tematy:
Anaemia
Dysphagia
Plummer Vinson syndrome
Salivary gland
Squamous cell carcinoma
Opis:
Plummer Vinson syndrome, also known as ‘Paterson Brown-Kelly’ syndrome is a syndrome associated with the triad of symptoms comprising microcytic hypochromic anaemia, oesophageal strictures and dysphagia. PVS (Plummer Vinson Syndrome) is commonly found in women of middle age especially in the fourth and fifth decade of life and is rarely reported in males and young females. Symptoms resulting from anaemia predominate the clinical picture, apart from additional features such as glossitis, angular cheilitis, and dysphagia. Dysphagia, however, is the main clinical feature of PVS. PVS carries an increased risk of development of squamous cell carcinoma of oesophagus and pharynx[1]. A classic case report of PVS associated with swelling of the salivary gland with clinical features, oral manifestations, malignant potential, differential diagnosis, investigation, and treatment is discussed here. This article carries the message that oral and pharyngeal manifestations should be considered to rule out malignancy in PVS, moreover, that PVS increases the risk factor of salivary gland squamous cell carcinoma. Early identification and diagnosis improves the prognosis and better chances of survival. We have to be familiar, therefore, with the oral manifestations of anaemia and be able to suspect PVS to aid in early diagnosis and prompt treatment. This case study was taken from Medcare hospital, Karimnagar, Telangana.
Źródło:
World News of Natural Sciences; 2018, 18, 2; 171-179
2543-5426
Pojawia się w:
World News of Natural Sciences
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Przydatność ultrasonografii w diagnostyce zespołu Sjögrena
The usefulness of ultrasound in the diagnostics of Sjögren’s syndrome
Autorzy:
Saied, Fadhil
Włodkowska‑Korytkowska, Monika
Maślińska, Maria
Kwiatkowska, Brygida
Kunisz, Wojciech
Smorawińska, Patrycja
Sudoł‑Szopińska, Iwona
Powiązania:
https://bibliotekanauki.pl/articles/1059021.pdf
Data publikacji:
2013
Wydawca:
Medical Communications
Tematy:
Sjögren’s syndrome
parotid gland
submandibular gland
ultrasound
ultrasound examination of the main salivary glands
ultrasonografia
ultrasonografia głównych gruczołów ślinowych
zespół sjögrena
ślinianka podżuchwowa
ślinianka przyuszna
Opis:
Sjögren’s syndrome is an autoimmune exocrinopathy which manifests itself with dryness of the eyes and the oral cavity. These symptoms comprise a so-called sicca syndrome (xerostomia and xerophthalmia). Two forms of this disease may be distinguished: primary Sjögren’s syndrome which affects salivary glands and secondary Sjögren’s syndrome with other autoimmune diseases present such as rheumatoid arthritis, systemic lupus erythematosus or systemic scleroderma. The diagnosis is based on the classification criteria established in 2002 by a group of American and European scientists (American-European Consensus Group), which involve the interview and physical examination as well as serological, histopathological and radiological tests. Most of these examinations show some limitations such as invasiveness, expensiveness or limited accessibility. The latest research suggests that ultrasound examination may appear promising in the diagnostics of the main salivary glands: submandibular and parotid glands. It is an accessible and relatively cheap examination with high sensitivity and specificity values which are comparable to those obtained via conventional means used in the diagnostics of this disease, i.e. biopsy of the minor salivary glands, sialography and scintigraphy, as well as superior to those obtained in sialometry and Schirmer’s test. Additionally, ultrasonography correlates with the results of magnetic resonance imaging. Therefore, a number of authors claim that US examination should be included in the classification criteria of Sjögren’s syndrome. The aim of this article is to present the diagnostic capacity of the US examination in Sjögren’s syndrome using the current ultrasound classification systems based on the grey-scale, Doppler and contrast-enhanced examinations. The latest research confirms that the most valuable diagnostic criterion in Sjögren’s syndrome is the heterogeneity of the glandular parenchyma. The outcome of the examination greatly depends on the examiner’s experience.
Zespół Sjögrena jest autoimmunologiczną egzokrynopatią, manifestującą się objawami suchości oka i jamy ustnej, składającymi się na tzw. zespół suchości (kserostomia i kseroftalmia). Można wyróżnić dwie postaci choroby: pierwotny zespół Sjögrena, zajmujący głównie gruczoły ślinowe, oraz wtórny zespół Sjögrena, z towarzyszącymi innymi chorobami autoimmunologicznymi, tj. reumatoidalnym zapaleniem stawów, toczniem układowym rumieniowym czy twardziną układową. Rozpoznanie choroby opiera się na kryteriach klasyfikacyjnych opracowanych w 2002 roku przez grupę naukowców z Ameryki i Europy (American‑European Consensus Group), które bazują na badaniach przedmiotowych i podmiotowych, serologicznych, histopatologicznych i radiologicznych. Większość tych badań wykazuje pewne ograniczenia, takie jak inwazyjność, wysoki koszt czy mała dostępność. Ostatnie prace wskazują, że obiecującą metodą w diagnostyce choroby jest badanie ultrasonograficzne głównych gruczołów ślinowych: ślinianek podżuchwowych i przyusznych. Jest to badanie dostępne, stosunkowo niedrogie, wykazujące wysoką czułość i swoistość, na poziomie porównywalnym do konwencjonalnych metod stosowanych w rozpoznawaniu tej choroby, tj. biopsji gruczołów ślinowych mniejszych, sialografii i scyntygrafii, i przewyższającym sialometrię i test Schirmera. Dodatkowo koreluje z wynikami rezonansu magnetycznego. Wielu autorów postuluje zatem włączenie badania ultrasonograficznego do kryteriów klasyfikacyjnych zespołu Sjögrena. Celem pracy jest przedstawienie możliwości diagnostycznych badania ultrasonograficznego w rozpoznawaniu zespołu Sjögrena, z uwzględnieniem dotychczas stosowanych ultrasonograficznych systemów klasyfikacyjnych, opierających się na badaniu w skali szarości, w opcji dopplerowskiej oraz z zastosowaniem środków kontrastujących. Najnowsze badania potwierdzają, że najcenniejszym diagnostycznie kryterium w rozpoznawaniu zespołu Sjögrena jest niejednorodność miąższu gruczołów. Wynik badania w dużej mierze zależy od doświadczenia badającego.
Źródło:
Journal of Ultrasonography; 2013, 13, 53; 202-211
2451-070X
Pojawia się w:
Journal of Ultrasonography
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Review and characteristics of 585 salivary gland neoplasms from a tertiary hospital registered in the Polish National Major Salivary Gland Benign Tumors Registry over a period of 5 years: a prospective study
Autorzy:
Piwowarczyk, Krzysztof
Bartkowiak, Ewelina
Klimza, Hanna
Greczka, Grażyna
Wierzbicka, Małgorzata
Powiązania:
https://bibliotekanauki.pl/articles/1397308.pdf
Data publikacji:
2020
Wydawca:
Index Copernicus International
Tematy:
benign neoplasms
characteristics
pleomorphic adenoma
registry
salivary gland
surgery
Opis:
Introduction: A Polish National Major Salivary Gland Benign Tumors Registry (SGR) is a report of benign salivary gland neoplasms (SGNs) from 26 different centres in Poland, introduced in 2014. The aim of this study is to analyze demographic characteristics and clinico-pathological factors of benign SGNs treated in large tertiary institutions and to determine possible correlations between selected variables. Material and method: Analysis of 585 patients recorded in SGR and operated on for SGNs in the Department of Otolaryngology and Laryngological Surgery, University of Medical Sciences, Poznań, Poland, over a 5-year period. Patient age, sex, occupation, place of residence, tumor location, size, histology, recurrence, facial nerve function after surgery, wound healing, surgery procedure, availability of pre-operative imaging examinations, fine-needle aspiration cytology (FNAC) results were analyzed. Results: 338 females and 247 males with a mean age of 53 years were operated on. In total, 96.2% of tumors originated from the parotid and 3.8% from the submandibular gland. The most frequent primary tumor diameter was 2–4 cm (59.5%) followed by <2 cm (29.2%) and >4 cm (8.4%). Tumors of over 4 cm were frequently removed by partial superficial parotidectomy, while those under 2 cm – by extracapsullar dissection (ECD). Pleomorphic adenomas (PA) were predominant (58.8%), followed by Warthin’s tumor (WT) – 37.1%. Patients with WT were on average 13.3 years older than patients with PA. Discussion: This research can be helpful to better understand the clinico-pathological features of SGNs. Long-termin hospital-based analysis is important for subsequent metaanalyses and comparisons with other centers. The reasons why not all patients’ data are reported to the national SGR should be further precisely analyzed.
Źródło:
Polish Journal of Otolaryngology; 2020, 74, 5; 1-6
0030-6657
2300-8423
Pojawia się w:
Polish Journal of Otolaryngology
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Submandibular salivary gland tumors: a clinicopathologic review of 58 cases
Autorzy:
Oleśna, Aleksandra
Kubiak, Marcin Jarosław
Kaczmarczyk, Dariusz
Morawiec-Sztandera, Alina
Powiązania:
https://bibliotekanauki.pl/articles/1399736.pdf
Data publikacji:
2018
Wydawca:
Index Copernicus International
Tematy:
Fine-needle aspiration cytology
Salivary gland neoplasm
Salivary gland cancer
Opis:
Objectives: Salivary gland tumors account for only 3% of head and neck tumors. Their character is mostly benign, although tumors of the submandibular gland are more often malignant. The purpose of this article was to evaluate the structure of patients operated due to submandibular gland tumor and to study the correlation between fine-needle aspiration cytology and postoperative histopathological examination. Methodology: We retrospectively analyzed the medical records of all patients with submandibular gland tumors. The collected data included the demographic structure, results of preoperative fine-needle aspiration cytology and postoperative histopathologic examination. Results: We analyzed 58 patients – 35 women and 23 men with a mean age of 56.6 years. The character of the lesion was benign in 45 cases and malignant in 13. The most frequent benign tumors were pleomorphic adenoma, inflammatory tumor and Warthin’s tumor, whereas most common malignancies were carcinoma planoepitheliale and lymphoma . There were four recurrences. Moreover, we compared results of preoperative fine-needle aspiration cytology and histopathological findings. The accuracy of this examination was almost 83%; 56% of incorrect results involved nondetection of malignancies. The sensitivity and specificity in the diagnosis of those tumors were 58.3% and 97.5%, respectively. Conclusions: The most common types of submandibular gland tumors are pleomorphic adenoma and carcinoma planoepitheliale and lymphoma amongst malignancies. Fine-needle aspiration cytology is accurate in the preoperative diagnosis, mistakes are mostly caused by underdiagnosis of malignant tumors.
Źródło:
Polski Przegląd Otorynolaryngologiczny; 2018, 7, 1; 31-35
2084-5308
2300-7338
Pojawia się w:
Polski Przegląd Otorynolaryngologiczny
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Surgical treatment results of parapharyngeal space tumors: a report of 22 cases
Autorzy:
Rzepakowska, Anna
Osuch-Wójcikiewicz, Ewa
Krupa, Zuzanna
Durmaj, Aneta
Niemczyk, Kazimierz
Powiązania:
https://bibliotekanauki.pl/articles/1398289.pdf
Data publikacji:
2018
Wydawca:
Index Copernicus International
Tematy:
parapharyngeal space
neck tumor
salivary gland tumor
surgical treatment
Opis:
Introduction: Parapharyngeal space (PPS) is the anatomical area lateral to the upper pharynx and clinically important due to PPS tumors. They account for less than 1% of head and neck neoplasms. Both benign and malignant neoplasms may arise there and typical for this localization is diversity of histological origin. Complete surgical excision is still the basis of treatment. Aim of the study: Evaluation of the results of surgical treatment of PPS tumors in the Department of Otolaryngology at the Medical University over the period 2015–2017. Material and methods: A retrospective analysis of medical records including complaints, physical examination, results of imaging studies, surgical approach, postoperative complication and histopathological results in 22 patients with a diagnosis of a PPS tumors. Results: The most frequent complaints reported by the patients were: discomfort in the throat, dysphagia, hearing disorders and a palpable tumor on the neck. Asymptomatic course of the disease was demonstrated in 4 cases. All patients were treated surgically: 2 with transoral approach, 9 with transparotid-transcervical approach, 11 with transcervical approach. In most cases the tumor was removed radically. In 2 patients intracapsular tumor resection was performed. Based on histopathological examination the benign lesions dominated (18/22). In 4 cases malignant neoplasms were diagnosed: carcinoma ex pleomorphic adenoma, adenoid cystic carcinoma and two cases of squamous cell carcinoma. The most common origin of PPS tumors was deep lobe of parotid gland and for this group 11 patients had diagnosis of pleomorphic adenoma. Other diagnosis included: paraganglioma, neurofibroma, hemangioma, lymphangioma and rhabdomyoma. Postoperative complications occurred in 9 patients and presented as hoarseness and dysphagia due to paresis of the lower group of cranial nerves (IX, X, XII). Significant intraoperative bleeding during surgery occurred in 2 cases and ligation of the external carotid artery was necessary. Conclusion: Due to the anatomical topography of PPS and its content with the essential vessels and the lower group of cranial nerves, the surgical treatment of pathology of this area is still a challenge for head and neck surgeons. The decrease of voice quality and impaired speech and swallowing should always be considered as complications post the surgical resection in PPS.
Źródło:
Polish Journal of Otolaryngology; 2018, 72, 4; 9-16
0030-6657
2300-8423
Pojawia się w:
Polish Journal of Otolaryngology
Dostawca treści:
Biblioteka Nauki
Artykuł
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