Temat: rhinosinusitis - Katalog OPAC zbiorów

Skocz do pozycji: 1.

Tytuł:: Chronic rhinosinusitis in children
Autorzy:: Zielnik-Jurkiewicz, Beata
Powiązania:: https://bibliotekanauki.pl/articles/1400060.pdf
Data publikacji:: 2017
Wydawca:: Index Copernicus International
Tematy:: rhinosinusitis
chronic
children
treatment
Opis:: CRS symptoms in children can be mild and uncharacteristic. The disease is multifactorial, and therefore requires a multifaceted, multidisciplinary approach. Treatment of CRS in children is difficult, infections often recur, and treatment methods are often ineffective. In children, surgery is performed infrequently, only when other therapies have failed. The first stage of surgery is adenoidectomy. Functional endoscopic surgery of the paranasal sinuses may be considered if no improvement of the patient after exhausting all possibilities of conservative treatment.
Źródło:: Polski Przegląd Otorynolaryngologiczny; 2017, 6, 1; 26-34
2084-5308
2300-7338
Pojawia się w:: Polski Przegląd Otorynolaryngologiczny
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 2.

Tytuł:: Intranasal steroid therapy – EPOS 2020
Autorzy:: Rot, Piotr
Rapiejko, Piotr
Jurkiewicz, Dariusz
Powiązania:: https://bibliotekanauki.pl/articles/1397321.pdf
Data publikacji:: 2020
Wydawca:: Index Copernicus International
Tematy:: corticosteroids
EPOS 2020
rhinosinusitis
Opis:: Introduction: Due to their strong, multidirectional anti-inflammatory activity, intranasal glucocorticoids are the mainstay of treatment in rhinosinusitis, including acute rhinosinusitis, chronic rhinosinusitis, and chronic rhinosinusitis with nasal polyps, as well as allergic rhinitis. Owing to its high systemic safety and high anti-inflammatory efficacy, mometasone furoate – a new-generation intranasal glucocorticoid – was approved in 2019 as an over-the-counter (OTC) medication for Polish patients diagnosed with allergic rhinitis. Scientific societies and expert groups recommend the use of intranasal glucocorticoids in a much broader range of indications. In February 2020, an updated version of the European Position Paper on Rhinosinusitis and Nasal Polyps (EPOS 2020) was published. Aim: This article discusses the role of nasal glucocorticoids in regimens used in the treatment of nasal sinusitis as published in EPOS 2020 with Polish country-specific realities being taken into account.
Źródło:: Polish Journal of Otolaryngology; 2020, 74, 3; 41-49
0030-6657
2300-8423
Pojawia się w:: Polish Journal of Otolaryngology
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 3.

Tytuł:: The importance of herbal medications in the treatment of rhinosinusitis in adults and children: an example of a five-ingredient herbal medicine
Znaczenie leków roślinnych w leczeniu zapalenia błony śluzowej nosa i zatok przynosowych u dorosłych i dzieci na przykładzie 5-składnikowego leku roślinnego
Autorzy:: Markowski, Jarosław
Powiązania:: https://bibliotekanauki.pl/articles/27320988.pdf
Data publikacji:: 2023-03-10
Wydawca:: Index Copernicus International
Tematy:: acute post-viral rhinosinusitis
acute rhinosinusitis
acute viral rhinosinusitis
bacterial rhinosinusitis
BNO 1016
chronic rhinosinusitis
Sinupret® extract
Sinupret® treatment of rhinosinusitis
bakteryjne zapalenie zatok przynosowych
leczenie zapalenia zatok
ostre powirusowe zapalenie zatok przynosowych
ostre zapalenie zatok przynosowych
przewlekłe zapalnie zatok przynosowych
Sinupret®
Opis:: This review paper presents current recommendations for the treatment of acute and chronic rhinosinusitis according to the European Position Paper on Rhinosinusitis and Nasal Polyps 2020, EPOS 2020. A particularly important and new element of these recommendations is to emphasize the role of phytotherapy as a rational treatment method, documented by a randomized, double-blind placebo-controlled trial (DBPC). An example of rational phytotherapy of rhinosinusitis is the BNO 1016 formulation recommended in EPOS 2020, known under the trade name of Sinupret®. Each of the pharmaceutical forms of BNO 1016 – coated tablets (powdered drug; dry extract) and oral drops (ethanol extract), is produced on the basis of the same combination of 5 herbal substances such as: gentian root (Gentianae radix), primrose flower (Primulae flos), sorrel herb (Rumicis herba), elderflower (Sambuci flos) and verbena herb (Verbenae herba). BNO 1016 has the status of a drug with well-established therapeutic use, with efficacy and safety confirmed in numerous clinical and preclinical studies. Used in the treatment of acute uncomplicated rhinosinusitis BNO 1016 has antiviral, secretolytic, anti-inflammatory and antibacterial effects confirmed in pharmacological studies. Importantly, the drug Sinupret® can be used in different age groups and therapeutic regimens (mono- and polytherapy), at any stage of sinusitis – from cold disease to bacterial rhinosinusitis (in combination with other drugs).
Niniejsza praca przeglądowa przedstawia aktualne zalecenia leczenia ostrego i przewlekłego zapalenia zatok przynosowych wg Europejskich Wytycznych na temat Zapalenia Zatok Przynosowych i Polipów Nosa, które zostały opublikowane na początku 2020 roku (ang. European Position Paper on Rhinosinusitis and Nasal Polyps 2020; EPOS 2020). Szczególnie istotnym i nowym elementem tych wytycznych jest podkreślenie roli fitoterapii jako racjonalnej metody leczenia, udokumentowanej randomizowanymi badaniami klinicznymi z podwójnie ślepą próbą z kontrolą placebo (ang. double-blind placebo-controlled trial; DBPC). Przykładem racjonalnej fitoterapii zapalenia zatok przynosowych jest rekomendowana w EPOS 2020 formulacja BNO 1016, znana pod nazwą handlową Sinupret®. Każda z postaci farmaceutycznych BNO 1016 – tabletki drażowane (sproszkowany lek; suchy wyciąg) oraz krople doustne (wyciąg etanolowy) – wyprodukowana jest na bazie tego samego złożenia 5 substancji roślinnych, takich jak: korzeń goryczki (Gentianae radix), kwiat pierwiosnka (Primulae flos), ziele szczawiu (Rumicis herba), kwiat bzu czarnego (Sambuci flos) i ziele werbeny (Verbenae herba). BNO 1016 ma status leku o ugruntowanym zastosowaniu leczniczym, skuteczności i bezpieczeństwie stosowania potwierdzonych w licznych badaniach klinicznych i przedklinicznych. Stosowany w leczeniu ostrego niepowikłanego zapalenia zatok przynosowych BNO 1016 wykazuje potwierdzone w badaniach farmakologicznych działanie: przeciwwirusowe, sekretolityczne, przeciwzapalne oraz przeciwbakteryjne. Co ważne, lek Sinupret® może być podawany w różnych grupach wiekowych i schematach terapeutycznych (mono- i politerapia), na każdym etapie zapalenia zatok, począwszy od choroby przeziębieniowej, skończywszy na bakteryjnym zapaleniu zatok przynosowych (w skojarzeniu z innymi lekami).
Źródło:: Polish Journal of Otolaryngology; 2023, 77, 1; 1-8
0030-6657
2300-8423
Pojawia się w:: Polish Journal of Otolaryngology
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 4.

Tytuł:: Tissue remodelling in chronic rhinosinusitis – review of literature
Autorzy:: Radajewski, Kamil
Wierzchowska, Małgorzata
Grzanka, Dariusz
Antosik, Paulina
Zdrenka, Marek
Burduk, Paweł
Powiązania:: https://bibliotekanauki.pl/articles/1397806.pdf
Data publikacji:: 2019
Wydawca:: Index Copernicus International
Tematy:: chronic rhinosinusitis
nasal polyps
tissue remodeling
Opis:: CRS is a process involving a number of adverse changes in the mucosa of the paranasal sinuses and nasal polyps, e.g. increased fibroblast proliferation, angiogenesis, increased formation of fibrous tissue (subepithelial fibrosis) and tissue destruction. There are biomarkers whose levels can be increased in chronic inflammation of the paranasal sinuses: peripheral blood eosinophilia, IgE immunoglobulin, cytokines – IL-4, IL-5, IL-13, IL-25, IL-33, periostin, P-glycoprotein, CXCL-12, CXCL-13, INF-Υ, TNFα, TGFβ1, albumins, eotaxin. These biomarkers are not pathognomonic for CRS. The concentration of biomarkers is also increased in bronchial asthma and atopic dermatitis. The TGFβ, in particular the β1 subunit, was identified as the main factor involved in the remodelling of tissue stroma. In conjunction with continuous improvement of tissue testing methods, it is advisable to search for new factors that will more accurately allow the assessment of tissue remodelling in the chronic processes of paranasal sinuses.
Źródło:: Polish Journal of Otolaryngology; 2019, 73, 5; 1-4
0030-6657
2300-8423
Pojawia się w:: Polish Journal of Otolaryngology
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 5.

Tytuł:: EPOS2020: What’s new for physician practitioners?
Autorzy:: Arcimowicz, Magdalena
Niemczyk, Kazimierz
Powiązania:: https://bibliotekanauki.pl/articles/1399060.pdf
Data publikacji:: 2020
Wydawca:: Index Copernicus International
Tematy:: acute rhinosinusitis
chronic rhinosinusitis
diagnostics
epidemiology
integrated care pathways
nasal polyps
rhinitis and paranasal sinusitis
treatment
Opis:: The European Position Paper on Rhinosinusitis and Nasal Polyps 2020 also abbreviated to EPOS2020, is the new edition of the European document devoted to the broadly understood topic of inflammation of the nasal mucosa and paranasal sinuses. The first edition appeared in 2005, followed by further editions in 2007 and 2012. In February 2020, we received the latest version, extended, somewhat modified, expanded to include the latest research and meta-analysis in the fields of: rhinology, rhinosurgery, epidemiology and reports on comorbidities. A completely new division of chronic sinusitis was presented. Recommendations based on the highest quality evaluations, resulting from the publication of the last eight years, also introduce a system based on integrated care pathways, or ICP in sinusitis. Chapters on pediatric aspects and sinus surgery have been expanded. EPOS2020 is addressed not only to doctors, but also to: nurses, pharmacists, other healthcare workers, as well as patients themselves, who often make the first attempts at treatment with OTC preparations, frequently based on the recommendations of pharmacists. The latest EPOS also specifies directions for further lines of research in the broadly understood field of rhinosinusitis.
Źródło:: Polski Przegląd Otorynolaryngologiczny; 2020, 9, 2; 7-17
2084-5308
2300-7338
Pojawia się w:: Polski Przegląd Otorynolaryngologiczny
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 6.

Tytuł:: Current issues in the diagnostics of paediatric chronic rhinosinusitis
Autorzy:: Standylo, A.
Obuchowska, A.
Horoch, T.
Mielnik-Niedzielska, G.
Powiązania:: https://bibliotekanauki.pl/articles/2098538.pdf
Data publikacji:: 2021
Wydawca:: Instytut Medycyny Wsi
Tematy:: pediatrics
diagnostics
chronic rhinosinusitis
child
adolescent
otolaryngology
Opis:: Introduction and objective. Paediatric chronic rhinosinusitis (PCRS) is a common disease in children. It is defined as an ongoing inflammation of the nasal cavity and sinuses lasting for over 12 weeks. Due to prevalence in the population, PCRS is associated with a high healthcare and financial burden. During the examination, attention should be paid to symptoms that may suggest chronic rhinosinusitis (CRS), because it may be underdiagnosed. Due to the chronicity of the inflammatory process and the similarity of symptoms to allergic rhinitis and adenoid hypertrophy, diagnosis and treatment are difficult. In this review, guidelines from The European Position Paper on Rhinosinusitis and Nasal Polyps (EPOS) 2020 and recent literature reports from Medline and Scopus database are analysed. Materials and methods. Information was obtained through a review and analysis of the PubMed Medline and Scopus databases. Brief description of the state of knowledge. Diagnostic difficulties with CRS can be caused by many factors. The EPOS guidelines recommend flexible or rigid nasal endoscopy as a preliminary objective method to assist in the recognition of CRS. Computed tomography (CT) is not recommended for routine management; therefore, CT is the gold standard for imaging when establishing a PCRS diagnosis or preparing for sinus surgery. The use of conventional X-ray imaging for chronic rhinosinusitis is limited and not recommended. Conclusions. Understanding the symptoms of chronic rhinosinusitis is of utmost importance in daily practice. Early initial assessment of symptoms in children with a high probability of CRS allows for early diagnosis and reduces the need for endoscopic and imaging examination.
Źródło:: Journal of Pre-Clinical and Clinical Research; 2021, 15, 3; 134-136
1898-2395
Pojawia się w:: Journal of Pre-Clinical and Clinical Research
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 7.

Tytuł:: Influence of nasal mucosa irritants on the occurrence of chronic rhinosinusitis without /and with polyps
Autorzy:: Olszewska, Aleksandra
Niewiadomski, Piotr
Olszewski, Jurek
Powiązania:: https://bibliotekanauki.pl/articles/1397254.pdf
Data publikacji:: 2021
Wydawca:: Index Copernicus International
Tematy:: chronic rhinosinusitis with/without nasal polyps
irritants
nasal mucosa
Opis:: Introduction: The aim of the study was to assess the effect of nasal mucosa irritants on the occurrence of chronic rhinosinusitis without/and with nasal polyps. Material and methods: The study involved 100 adult participants, including 39 women and 61 men, aged 21–68, diagnosed and treated at the Department of Otolaryngology, ENT Oncology, Audiology and Phoniatrics at the University Clinical Hospital WAM in Łódź. Based on the otorhinolaryngological and imaging (CT) tests they were divided into two groups: I – 50 patients, including 23 women and 27 men, aged 21–64 – with chronic rhinosinusitis without nasal polyps, II – 50 patients, including 16 women and 34 men, aged 22–68 – with chronic rhinosinusitis with nasal polyps. The control group consisted of 50 people (group III), including 25 women and 25 men, aged 18–30, students of the Faculty of Military Medicine at the Medical University of Lodz. All respondents completed a prepared questionnaire consisting of 17 questions addressed in the form of an anonymous interview among patients treated in the Department of Otolaryngology, ENT Oncology, Audiology and Phoniatrics. Results: The conducted surveys indicate the impact of the following factors in pathogenesis of chronic rhinosinusitis without/ with nasal polyps: exogenous factors (viruses, bacteria, fungi, drugs, injuries, toxic substances, environmental pollution), general endogenous factors (allergy, hypersensitivity to acetylsalicylic acid and its derivatives, hormonal disorders, supraesophageal reflux disease, granulation disease, immunity disorders, local endogenous factors. Conclusions: In the examined material, patients with chronic rhinosinusitis without/and nasal polyps in most cases are in the age range 51–60 years and over 60 years, they most often live in large cities over 250 thousand inhabitants, suffer from allergic rhinorhinitis in 38.0% in group I and 36.0% in group II, rapid temperature changes and dry air have a negative impact on comfort of breathing. The conducted surveys confirm that the cause of chronic rhinosinusitis with polyps is multifactorial, but a significant factor affecting typical tissue remodeling in this disease is long-term breathing of polluted atmospheric air.
Źródło:: Polish Journal of Otolaryngology; 2021, 75, 1; 36-44
0030-6657
2300-8423
Pojawia się w:: Polish Journal of Otolaryngology
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 8.

Tytuł:: Functional endoscopic sinus surgery (FESS) in unilateral sinus disease
Autorzy:: Mielcarek-Kuchta, Daniela
Simon, Karolina
Kondratowicz, Dawid
Łukomska, Zofia
Rybak-Korytowska, Aleksandra
Powiązania:: https://bibliotekanauki.pl/articles/1398482.pdf
Data publikacji:: 2017
Wydawca:: Index Copernicus International
Tematy:: unilateral sinus disease
FESS
chronic rhinosinusitis
inverted papilloma
mycosis
Opis:: Background: Unilateral sinus disease (USD) occurs in 23 % of all cases. It is believed that it is mainly associated with cancer development. Retrospective data from large rhinological centers show that the most common USD is chronic rhinosinusitis (CRS), followed by mycosis, inverted papilloma and finally cancer, but only in a small percent of cases. The aim of the study: The analysis of USD in the group of patients who underwent FESS at the secondary referral center. Material and Method: The retrospective study of patients treated for USD in the Department of Otolaryngology in the Provincial Hospital in Poznan between June 2014 and June 2016. The analysis includes age, sex, the localization of lesions, histopathological and microbiological results, an extension of the surgery and treatment results. Results: Over the analyzed period of time, 415 FESS for chronic sinusitis were performed. In this group, 83 patients underwent surgery for USD. There were 35 women and 48 men.CRS was found in 48 cases, mycosis in nine cases, 12 patients were operated for non-malignant tumors, such as inverted papilloma (9), osteoma (2) and fibrosis tumor(1); seven patients had a choanal polyp and two of them had a foreign body in maxillary sinus – a tooth root lying loose. Four patients were diagnosed with a hypoplastic maxillary sinus and one patient suffered from frontal sinus pyocele. One side endoscopic opening of all sinuses was performed in the group with CRS, endoscopic medial maxillectomy was conducted in patients with inverted papilloma, and an isolated opening of the affected sinus was performed in the cases with mycosis. Conclusions: USD must be always suspected of malignant degeneration until proven otherwise. Endoscopic sinus surgery with the use of angled scope allows for the removal of even very extensive lesions. In our opinion, the extent of operation is determined by the nature of pathology. While extensive surgery is recommended in patients with inverted papilloma, a limited procedure should be performed in those with isolated mycosis.
Źródło:: Polish Journal of Otolaryngology; 2017, 71, 5; 29-35
0030-6657
2300-8423
Pojawia się w:: Polish Journal of Otolaryngology
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 9.

Tytuł:: A randomized, double-blind, placebo-controlled study to investigate the use of bacteriophages in patients with chronic rhinosinusitis with nasal polyps
Autorzy:: Dobretsov, Konstantin Grigorievich
Kolenchukova, Oxana
Sipkin, Alexander
Bellussi, Luisa Maria
Ciprandi, Giorgio
Passali, Desiderio
Powiązania:: https://bibliotekanauki.pl/articles/23203235.pdf
Data publikacji:: 2021-06-30
Wydawca:: Index Copernicus International
Tematy:: bacteria
bacteriophages
chronic rhinosinusitis with nasal polyps
cytokines
local treatment
Opis:: Introduction: A randomized, double-blind, placebo-controlled study investigates the use of bacteriophages in the treatment of chronic rhinosinusitis with nasal polyps. Material and methods: 40 adult patients with chronic rhinosinusitis with nasal polyps were examined. All patients underwent functional endoscopic sinus surgery. After the surgery, 20 patients were administered an intranasal gel with bacteriophage mixture (Otofag, Micromir, Russia) twice a day for ten weeks, while 20 other patients received a placebo solution. Results: On the 10th day, IL-1β secretion diminished (63 mg/ml versus 440 mg/ml in control). There was a decrease in the total number of microorganisms and Enterobacteriaceae (5.7 x 10⁶ CFU/ml versus 1.2 x 10⁹ CFU/ml in the control group) and the absence of Streptococci (versus 2.1 x 10⁹ CFU/ml in control) was noted on the 30th day of treatment in the group receiving bacteriophage mixture. On the 10th day, a decrease in the activity of secretory IL-1β and IL-8 strongly and very strongly correlated with a total number of microorganisms (r = 0.7; r = 0.9, respectively), as well as a decrease in the activity of secretory IL-8 correlated with the number of Enterobacteriaceae (r = 0.72) and Staphylococci (r = 0.65) in the experimental group treated with bacteriophages. On the 30th day, the decrease in serum IL-1β significantly correlated with the total number of microorganisms (r = 0.80) and Enterobacteriaceae (r = 0.90) in the experimental group. Conclusions: The administration of bacteriophages restored the balance of microorganisms in the nasal cavity and decreased inflammatory response in chronic rhinosinusitis with nasal polyps. Changes such as an inflammation dampening could potentially contribute to reducing recurrent growth of polyp tissue in the future.
Źródło:: Polish Journal of Otolaryngology; 2021, 75, 6; 33-37
0030-6657
2300-8423
Pojawia się w:: Polish Journal of Otolaryngology
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 10.

Tytuł:: Chronic sphenoid sinusitis with bone destruction – surgical treatment of five patients
Autorzy:: Wardas, Piotr
Piotrowska-Seweryn, Agnieszka
Markowski, Jarosław
Kaspera, Maciej
Symela, Joanna
Ślaska-Kaspera, Aleksandra
Powiązania:: https://bibliotekanauki.pl/articles/1400408.pdf
Data publikacji:: 2017
Wydawca:: Index Copernicus International
Tematy:: sphenoidal sinus
allergic rhinosinusitis
functional endonasal sinus surgery (FESS)
bone destruction
Opis:: Chronic sinusitis of the sphenoid sinus is a disease that can cause a number of complications, mainly intracranial and ophthalmic ones. The proximity of critical anatomical structures such as the internal carotid artery, cranial nerves, cavernous sinus, dura mater and cerebral lobes puts any or all of these at risk and challenge due to the disease process itself and in surgical management as well. Infiltration of bone structures or its damage in the mechanism of compression is recorded in cases of fungal rhinosinusitis (FRS), Wegener's granulomatosis or actinitis with manifestation in the area of the sinuses. The authors present five patients with chronic sinusitis with bone destruction of the sphenoid sinus. Suspicion of fungal etiology in all cases was based on computed tomography (CT) images. The authors pay particular attention to the role of functional endoscopic sinus surgery (FESS) in chronic sinusitis with bone destruction, especially of a fungal etiology.
Źródło:: Polski Przegląd Otorynolaryngologiczny; 2017, 6, 3; 51-58
2084-5308
2300-7338
Pojawia się w:: Polski Przegląd Otorynolaryngologiczny
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 11.

Tytuł:: Development of bacterial resistance during treatment with topical gentamicin for chronic rhinosinusitis in patients with cystic fibrosis and primary ciliary dyskinesis. Retrospective case series
Autorzy:: Kisiel, Marta
Sjölander, Isabella
Klar, Agnes
Asplund Stenkvist, Monika
Laurell, Göran
Powiązania:: https://bibliotekanauki.pl/articles/1397315.pdf
Data publikacji:: 2020
Wydawca:: Index Copernicus International
Tematy:: chronic rhinosinusitis
cystic fibrosis
gentamycin nasal spray
gentamycin resistance
primary ciliary dyskinesis
Opis:: Background: The management of chronic rhinosinusitis (CRS) in patients with cystic fibrosis (CF) and primary ciliary dyskinesia (PCD) is still a challenge. At our institution we have used gentamycin nasal spray, extemporaneously produced, for prophylactic treatment of moderate-to-severe CRS. The aim of this study was to investigate the gentamycin susceptibility of bacteria in sputum samples in CF and PCD patients treated for CRS. Methodology: Patients with CF and PCD who were prescribed gentamycin nasal spray for CRS and had sputum bacterial cultures taken pre-treatment and followed-up at least once after ≥6 months were retrospectively included. Microbiological data were descriptively analysed in terms of bacterial species and resistance to gentamycin. Results: A case series of 17 CF and 12 PCD patients passed the inclusion criteria. Of those cases, three (18%) CF patients and one (8%) PCD patient developed resistance to gentamycin during treatment with gentamycin nasal spray. In all four cases, the resistant bacterial isolates were P. aeruginosa. Additionally, two CF patients already had P. aeruginosa isolates resistant to gentamycin in the pre-treatment culture. In further two CF patients, the multi-resistant Burgdorferi cepacia complex, including gentamycin resistance, was identified. P. aeruginosa and S. aureus in CF and P. aeruginosa and H. influenza in PCD were the predominant bacterial species. Conclusions: The study showed that there was moderate incidence of gentamycin resistance in CF and PCD patients at our institution. However, further prospective studies are needed to confirm the outcomes.
Źródło:: Polish Journal of Otolaryngology; 2020, 74, 3; 33-40
0030-6657
2300-8423
Pojawia się w:: Polish Journal of Otolaryngology
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 12.

Tytuł:: Antibiotic therapy of acute upper respiratory tract infections and otitis media in adults
Autorzy:: Paź, Aleksandra
Arcimowicz, Magdalena
Powiązania:: https://bibliotekanauki.pl/articles/1399732.pdf
Data publikacji:: 2018
Wydawca:: Index Copernicus International
Tematy:: antibiotics
drug resistance
acute rhinosinusitis
acute pharyngitis
acute laryngitis
acute otitis media
Opis:: An estimated 50% of antibiotic prescriptions may be unjustified in the outpatient setting. Viruses are responsible for most acute respiratory tract infections. The viral infections are often self-limiting and only symptomatic treatment remains effective. Bacteria are involved in a small percentage of infections etiology in this area. In the case of a justified or documented suspicion of a bacterial infection, antibiotic therapy may be indicated. Based on the Polish „Recommendations for the management of non-hospital respiratory infections 2016”, the indications, the rules of choice, the appropriate dosing schedules and the therapy duration, in the most frequent upper respiratory tract infections in adults, have been presented. Implementation of the presented recommendations regarding our Polish epidemiological situation, will significantly reduce the tendency to abuse antibiotics, and thus will limit the spread of drug-resistant microorganisms.
Źródło:: Polski Przegląd Otorynolaryngologiczny; 2018, 7, 1; 1-7
2084-5308
2300-7338
Pojawia się w:: Polski Przegląd Otorynolaryngologiczny
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 13.

Tytuł:: Recommendation for use of Sinupret extract in acute rhinosinusitis
Autorzy:: Wysocki, Jarosław
Powiązania:: https://bibliotekanauki.pl/articles/1400396.pdf
Data publikacji:: 2017
Wydawca:: Index Copernicus International
Tematy:: acute rhinosinusitis
sinupret
sinupret extract
bioactive ingredients
mechanism of action
documented therapeutic effect
Opis:: Acute and chronic rhinosinusitis is the most common problem encountered in ENT practice. Nearly all cases of acute rhinosinusitis are of viral background. Further course of the disease is determined by the condition of mucosal membranes, systemic immune strength, virulence of the infectious agent and the morphology of paranasal sinuses. Medications used in acute rhinosinusitis provide symptomatic treatment, their effect being aimed at reduction of inflammation and swelling. Products obtained from medicinal plants may provide an alternative to these medications. In vitro studies have shown that these products demonstrate anti-inflammatory, immunostimulating, anti-edemic, and antiviral effects. With the market placement of Sinupret extract, the armamentarium of therapeutic has been extended by a concentrated product characterized by strength comparable to that of synthetic analgesic and anti-inflammatory drug as well as by additional, documented antiviral effect. The article discusses the composition of Sinupret extract, the mechanisms of action of its active substances, and the results of preclinical and clinical studies of Sinupret and Sinupret extract.
Źródło:: Polski Przegląd Otorynolaryngologiczny; 2017, 6, 3; 59-66
2084-5308
2300-7338
Pojawia się w:: Polski Przegląd Otorynolaryngologiczny
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 14.

Tytuł:: Assessment of the effect of inflammatory changes and allergic reaction on TAS2R38 receptor expression in patients with chronic sinusitis (CRS)
Autorzy:: Piskadło-Zborowska, Karolina
Stachowiak, Małgorzata
Sarnowska, Elżbieta
Jowik, Rafał
Dżaman, Karolina
Powiązania:: https://bibliotekanauki.pl/articles/1397310.pdf
Data publikacji:: 2020
Wydawca:: Index Copernicus International
Tematy:: bitter taste receptor
chronic rhinosinusitis
TAS2R38 gene
TAS2R38 receptor
Opis:: Background: Chronic rhinosinusitis (CRS) is one of the most common health complaints affecting 15% of the world’s population. Recent reports confirm the participation of sensory organs in the defense process against pathogenic microorganisms. The bitter taste receptor TAS2R38 is described to play a role in the upper airway defense system. Purpose: The purpose of this study was to assess the function of the bitter taste receptor in correlation with the severity of CRS, sensory organ disorders and allergic reaction. Material and method: The study contained 100 patients undergoing nasal surgery, divided into two groups: CRS with and without nasal polyps. The control group consisted of patients undergoing septoplasty after excluding rhinosinusitis. Sinus mucosa samples obtained during surgery were used to assess TAS2R38 expression using immunohistochemistry. The IgE level was indicated from blood samples collected from patients. The Sniffin’ Sticks Test was performed. Results: CRS patients had higher expression of TAS2R38 receptor compared to controls (p = 0.0175). A statistically significantly higher TAS2R38 H-score in nasal mucosa was found among patients with a higher inflammation process in CT scan (p = 0.001), higher IgE level (p = 0,04) and an abnormal result of the Sniffin’ Sticks Test. Conclusions: Patients with CRS had significant TAS2R38 receptor overexpression correlating with the severity of inflammatory changes in CT scans, abnormal perception of smells and higher IgE level. A cumulative impact was found between the inflammatory changes, smell disfunction and the severity of subjective symptoms of CRS (according to EPOS) and the intensity of cell staining (index H-score).
Źródło:: Polish Journal of Otolaryngology; 2020, 74, 5; 17-23
0030-6657
2300-8423
Pojawia się w:: Polish Journal of Otolaryngology
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 15.

Tytuł:: Place of phytotherapy in the treatment of acute infections of upper respiratory tract and upper gastrointestinal tract
Autorzy:: Pietruszewska, Wioletta
Barańska, Magda
Wielgat, Jakub
Powiązania:: https://bibliotekanauki.pl/articles/1398294.pdf
Data publikacji:: 2018
Wydawca:: Index Copernicus International
Tematy:: acute rhinosinusitis
acute pharyngitis
phytotherapy
acute infections of an upper respiratory tract and upper gastrointestinal tract
Opis:: Acute infections of the upper respiratory tract and upper gastrointestinal tract (mouth and throat) are still the most common reason for reporting to the general practitioner or ENT specialist. Despite the fact that the most common causative agent of these diseases is a virus, antibiotics are still flavored in about 60-80% of patients who report to the doctor. In consensuses such as EPOS, WHO reports and other local/ / national reports, there is a need to limit antibacterial treatment for and to replace it with symptomatic and anti-inflammatory drugs. In addition to intranasal steroids and mucocutaneous decongestants, supplementary treatment should be considered which resolves persistent symptoms. Plant preparations are used here. The growing role of rational phytotherapy is emphasized, especially due to the most frequent the etiological factor of these infections, i.e. viruses. Modern phytotherapy is a part of pharmacology, and all preparations based on plants meet the standards for of medicines and are subject to standard registration procedures. The article discusses the use and mechanism of action of selected herbs, among others: sorrel, elderberry, yarrow, and horsetail in the treatment of upper respiratory tract infections and upper gastrointestinal tract. The phytotherapy shows good efficacy and tolerance and can be used both in children and adults in recurrent infections of the upper respiratory tract. It is worth paying attention to the combined preparations, the components of which have the effects confirmed by randomized trials and long-term registration for use in treatment, both during the first signs of cold and its further duration, and supportive as support in chronic inflammation especially of the paranasal sinuses.
Źródło:: Polish Journal of Otolaryngology; 2018, 72, 4; 42-50
0030-6657
2300-8423
Pojawia się w:: Polish Journal of Otolaryngology
Dostawca treści:: Biblioteka Nauki

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