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Tytuł:
Early diagnosis and treatment of rheumatoid arthritis in primary health care
Autorzy:
Kanecki, Krzysztof
Tyszko, Piotr
Powiązania:
https://bibliotekanauki.pl/articles/552635.pdf
Data publikacji:
2014
Wydawca:
Stowarzyszenie Przyjaciół Medycyny Rodzinnej i Lekarzy Rodzinnych
Tematy:
rheumatoid arthritis
primary health care
family medicine
Źródło:
Family Medicine & Primary Care Review; 2014, 4; 365-369
1734-3402
Pojawia się w:
Family Medicine & Primary Care Review
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Simplified vs modified (reduced) ultrasound 6 joint score in assessing disease activity in rheumatoid arthritis patients
Autorzy:
Gabal, Mervat Mamdouh Abo
Eldin, Amina Badr
Elserwy, Maha Ahmed
Mohammed, Mostafa Adel
Powiązania:
https://bibliotekanauki.pl/articles/36146164.pdf
Data publikacji:
2024-03-30
Wydawca:
Uniwersytet Rzeszowski. Wydawnictwo Uniwersytetu Rzeszowskiego
Tematy:
activity
6-joint score
rheumatoid arthritis
ultrasound
Opis:
Introduction and aim. With increasing ultrasound US assessment opportunities for tight rheumatoid arthritis (RA) management, more simplified accurate US-assessment is desired in clinical practice. Aim of the work is assessing modified vs simplified ultrasound 6-joint scores relevance in assessing rheumatoid arthritis disease activity. Material and methods. Fifty-five RA patients were subjected to detailed history, clinical, and musculoskeletal examination with disease activity assessment by clinical disease activity index, simple disease activity index and disease activity score in 28 joints. Complete blood count, erythrocyte sedimentation rate, C-reactive protein, rheumatoid factor, anti-cyclic citrullinated peptide antibodies were done. Patients underwent US examination (gray-scale and power Doppler) for wrist, 2nd and 3rd metacarpophalangeal and knee joints bilaterally. Synovitis composite score was added. Two US indices were constructed: simplified S6 and modified M6 joint scores. Results. Statistical significant positive correlations were high between S6/M6 score parameters (total, grey-scale (GS), power doppler (PD), Composite) and disease activity markers. Both M6 and S6 scores differentiated mild-moderate and moderate-severe disease activity patients. However, only S6 score differentiated remission from mild disease activity patients. Conclusion. Ultrasound 6-joint scores (especially simplified S6) were rapid, easy and sensitive ultrasound tools assessing rheumatoid arthritis disease activity in clinical practice.
Źródło:
European Journal of Clinical and Experimental Medicine; 2024, 22, 1; 36-44
2544-2406
2544-1361
Pojawia się w:
European Journal of Clinical and Experimental Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Wpływ czasu trwania RZS na temperaturę stawów objętych stanem zapalnym
The influence of duration of rheumatoid arthritis on the temperature of inflammed joints
Autorzy:
Wasilewska, A.
Chwiećko, J.
Domysławska, I.
Powiązania:
https://bibliotekanauki.pl/articles/98960.pdf
Data publikacji:
2017
Wydawca:
Politechnika Śląska. Katedra Biomechatroniki
Tematy:
reumatoidalne zapalenie stawów
termowizja
rheumatoid arthritis
termovision
Opis:
Reumatoidalne Zapalenie Stawów (RZS) jest przewlekłą, zapalną chorobą układową tkanki łącznej. Celem niniejszej pracy była ocena wpływu czasu trwania choroby, od momentu postawienia diagnozy RZS, na temperaturę stawów objętych procesem zapalnym. Za pomocą kamery termowizyjnej przebadano następujące stawy: stawy nadgarstka, stawy śródręczno-paliczkowe, stawy międzypaliczkowe bliższe, stawy międzypaliczkowe dalsze dłoni prawej i lewej oraz stawy: skokowo goleniowy i śródstopno-paliczkowy stopy prawej i lewej. Zaobserwowano istotnie niższą temperaturę stawu skokowo-goleniowego stopy prawej u pacjentów chorujących dłużej niż 10 lat w porównaniu z osobami zdrowymi.
Rheumatoid Arthritis (RA) is a chronic inflammatory disease of human connective tissue. The aim of the study was to assess the impact of RA duration on the temperature of inflamed joints. Temperatures of the following joints were measured: wrist joints, metacarophalangeal joints, proximal interphalangeal joints, distal interphalangeal joints of left and right hand as well as ankle joints and metatarsophalangeal joints of right and left foot. Significantly lower right ankle joint temperature was observed for patients of more than 10 years’ disease duration compared to healthy subjects
Źródło:
Aktualne Problemy Biomechaniki; 2017, 12; 81-88
1898-763X
Pojawia się w:
Aktualne Problemy Biomechaniki
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Coping strategies observed in women with rheumatoid arthritis
Autorzy:
Janiszewska, M.
Barańska, A.
Kanecki, K.
Karpińska, A.
Firlej, E.
Bogdan, M.
Powiązania:
https://bibliotekanauki.pl/articles/2085883.pdf
Data publikacji:
2020
Wydawca:
Instytut Medycyny Wsi
Tematy:
rheumatoid arthritis
pain
psychological stress
coping strategies
Opis:
When faced with a chronic disease such as rheumatoid arthritis, the patient attempts to cope with the stressful situation by applying coping strategies. The main aim of rheumatoid treatment is not only improving health but also increasing the quality of life. The research objective was to determine the relationship among socio-demographic factors, duration of the disease and its associated ailments, attitude to the disease, self-assessment of one’s knowledge of RA, and the application of coping strategies in stressful situations by women with rheumatoid arthritis. The study involved 193 patients of the Clinic of Rheumatology and Systemic Connective Tissue Diseases, and the Rheumatology Unit of the Specialist Outpatient Clinic of the Independent Public Teaching Hospital No. 4 in Lublin, from November 2016 – June 2017. The Coping Orientations to Problems Experienced Inventory (COPE) Questionnaire and an author’s Original Questionnaire were used in the study. Analysis of variance (ANOVA) and Tukey’s range test were applied for statistical analysis. A p-value<0.05 defined the statistical differences. Analysis was performed using the commercial SPSS Statistics 19 software (IBM Corp., Armonk, NY, USA). The respondents usually use instrumental social support (11.5±1.7), focus on and vent emotions (11.4±1.9), use emotional social support (11.4±1.8), employ active coping (11.4±2.1) and positive reinterpretation and growth (11.2±1.8), and least often rely on their sense of humour (5.5±1.4) or use alcohol or drugs (5±1.1). The factors which determine the types of strategy used are age, education, the duration of the disease, ailments experienced, and attitude towards the disease. Those respondents who declared a greater knowledge of RA more often applied positive reinterpretation and growth, and more rarely used alcohol or drugs. In the treatment and rehabilitation processes it is important to reinforce in the patient positive expectations for the treatment, seek advantages and benefits in one’s present health status, and educate patients about the disease, its therapy and appropriate coping strategies.
Źródło:
Annals of Agricultural and Environmental Medicine; 2020, 27, 3; 401-406
1232-1966
Pojawia się w:
Annals of Agricultural and Environmental Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Cytokines of the Th1 and Th2 type in sera of rheumatoid arthritis patients; correlations with anti-Hsp40 immune response and diagnostic markers
Autorzy:
Tukaj, Stefan
Kotlarz, Agnieszka
Jóźwik, Agnieszka
Smoleńska, Żaneta
Bryl, Ewa
Witkowski, Jacek
Lipińska, Barbara
Powiązania:
https://bibliotekanauki.pl/articles/1040376.pdf
Data publikacji:
2010
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
rheumatoid arthritis
Hsp40
cytokines
heat shock proteins
Opis:
Rheumatoid arthritis (RA) is a chronic, systemic inflammatory disease which affects approximately 1% of the population worldwide. Recent research on the role of heat shock proteins (Hsps) in RA development indicates that they may have pro- or anti-inflammatory effect, most probably via modulating cytokine secretion. We investigated type Th1 (INFγ, TNFα, IL-2) and type Th2 (IL-10, IL-6, IL-4) cytokine levels in sera of RA patients and healthy controls, using flow cytometric bead array assay, and searched for correlations between the cytokine levels and serum antibodies against bacterial (DnaJ) and human (Hdj1, Hdj2 and Hdj3) Hsp40 proteins, as well as clinical and laboratory parameters. The levels of all cytokines studied were significantly increased in RA patients; the highest increase relative to healthy controls (7-fold) was observed for IL-6 and its levels correlated positively with the antibodies directed to DnaJ and to the C-terminal domain of Hdj2, and with diagnostic parameters (DAS 28, Steinbrocker RTG criteria, ARA/7, ESR, TEN, SW and GH). INFγ levels correlated negatively with DAS 28, ESR, TEN and SW. No correlations were found for TNFα, IL-2 or IL-4. Our results support the hypothesis of Hsp40 involvement in RA as well as indicate that IL-6 serum level is a good marker of the RA activity.
Źródło:
Acta Biochimica Polonica; 2010, 57, 3; 327-332
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Collagen type II modification by hypochlorite.
Autorzy:
Olszowski, Sławomir
Mak, Paweł
Olszowska, Ewa
Marcinkiewicz, Janusz
Powiązania:
https://bibliotekanauki.pl/articles/1043624.pdf
Data publikacji:
2003
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
rheumatoid arthritis
hypochlorite
collagen
taurine chloramine
oxidative modification
Opis:
Oxidation of proteins is a common phenomenon in the inflammatory process mediated by highly reactive agents such as hypochlorite (HOCl/OCl-) produced by activated neutrophils. For instance, in rheumatoid arthritis hypochlorite plays an important role in joint destruction. One of the major targets for HOCl/OCl- is collagen type II (CII) - the primary cartilage protein. In our study, HOCl/OCl- mediated collagen II modifications were tested using various methods: circular dichroism (CD), HPLC, ELISA, dynamic light scattering (DLS), fluorimetry and spectrophotometry. It was shown that hypochlorite action causes deamination with consecutive carbonyl group formation and transformation of tyrosine residues to dichlorotyrosine. Moreover, it was shown that ammonium chloramine (NH2Cl) formed in the reaction mixture reacts with CII. However, in this case the yield of carbonyl groups and dichlorotyrosine is lower than that observed for HOCl/OCl- by 50%. CD data revealed that collagen II exists as a random coil in the samples and that chlorination is followed by CII fragmentation. In the range of low HOCl/OCl- concentrations (up to 1 mM) 10-90 kDa peptides are predominant whereas massive production of shorter peptides was observed for high (5 mM) hypochlorite concentration. DLS measurements showed that chlorination with HOCl/OCl- decreases the radius of collagen II aggregates from 30 to 6.8 nm. Taking into account the fact that chlorinated collagen is partially degraded, the DLS results suggest that smaller micelles are formed of the 10-90 kDa peptide fraction. Moreover, collagen chlorination results in epitope modification which affects CII recognition by anti-CII antibodies. Finally, since in the synovial fluid the plausible hypochlorite concentration is smaller than that used in the model the change of size of molecular aggregates seems to be the best marker of hypochlorite-mediated collagen oxidation.
Źródło:
Acta Biochimica Polonica; 2003, 50, 2; 471-479
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Correlation between rheumatoid arthritis and periodontitis
Autorzy:
Zielińska, Anna
Tabarkiewicz, Jacek
Powiązania:
https://bibliotekanauki.pl/articles/2216798.pdf
Data publikacji:
2022-12-30
Wydawca:
Uniwersytet Rzeszowski. Wydawnictwo Uniwersytetu Rzeszowskiego
Tematy:
Aggregatibacter actinomycetemcomitans
periodontitis
Porphyromonas gingivalis
rheumatoid arthritis
risk factors
Opis:
Introduction and aim. The association between periodontitis (PD) and rheumatoid arthritis (RA) has been analyzed and described in literature. Periodontal pathogens, such as Porphyromonas gingivalis and Aggregatibacter actinomycetemcomitans are pointed as the common factors for both diseases. In this work we demonstrate that treatment of dental and oral diseases is an unconditional requirement for patients with RA. Material and methods. PubMed was searched with the keyword “rheumatoid arthritis” and “periodontitis” from May 1999 to January 2022, showed 181 articles. Ultimately 72 articles were included in the review. Analysis of the literature. The above mentioned pathogens exhibit multiple mechanisms that disturb immune and inflammatory responses of the human organism. Those mechanisms lead to the periodontal disease (PD) that may activate the systematic reactions which in turn lead to intensification of systematic diseases such as rheumatoid arthritis (RA). P. gingivalis has the ability to expresses PAD enzyme (peptidylarginine deiminase) and activates the citrullization process. Moreover, the bacterium produces gingipain cysteine proteinases, which degrade the mechanisms of immunological system. The latter pathogen, A. actinomycetemcomitans, expresses hypercitrullization in neutrophils. Conclusion. Both pathogens influence inflammatory response of the organism, through the common pro-inflammatory mediators for periodontitis and rheumatoid arthritis, intensify the clinical manifestations of both diseases.
Źródło:
European Journal of Clinical and Experimental Medicine; 2022, 4; 451-458
2544-2406
2544-1361
Pojawia się w:
European Journal of Clinical and Experimental Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
The effect of a physical therapy programme on the condition of upper limb muscles in patients with rheumatoid arthritis
Autorzy:
Grygus, Igor
Nogas, Anzhela
Powiązania:
https://bibliotekanauki.pl/articles/29520458.pdf
Data publikacji:
2023-12-31
Wydawca:
Uniwersytet Rzeszowski. Wydawnictwo Uniwersytetu Rzeszowskiego
Tematy:
dynamometry
muscles strength
physical therapy
rheumatoid arthritis
strength index
Opis:
Introduction and aim. Rheumatoid arthritis is a chronic progressive systemic disease of the connective tissue affecting the joints, mainly small, of the erosive-destructive polyarthritis type, and frequent systemic inflammatory damage to internal organs. The purpose of the research is to evaluate the effectiveness of physical therapy on the muscles of upper limbs in patients with rheumatoid arthritis by the dynamics of muscle strength and strength index. Material and methods. To determine the strength of the muscles of the affected upper limbs were used dynamometry, calculated strength index as a percentage to assess the functional ability of the affected limb. All patients were divided into control (n=92) and main (n=96) groups, taking into account the functional insufficiency of the joints. Results. After 6 months of physical therapy, muscle strength indicators in the main group of patients with 1st degree of functional joints insufficiency (FJI) in the affected right limb increased by 3.1 kg, in the left by 3 kg; with 2nd degree FJI – in the right limb by 4.2 kg, in the left – by 3.7 kg, significantly exceeded the same indicators in patients of the control group (р<0.05). Similarly, there was an increase in the strength index in the patients of the main group. Conclusion. Physical therapy technology has been developed and implemented effectively influenced the increase in muscle strength and strength index of affected upper limbs of the main group of patients with rheumatoid arthritis.
Źródło:
European Journal of Clinical and Experimental Medicine; 2023, 4; 723-729
2544-2406
2544-1361
Pojawia się w:
European Journal of Clinical and Experimental Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Czynniki wpływające na pomiar termowizyjny w reumatoidalnym zapaleniu stawów
Factors influencing thermographic measurment in rheumatoid arthritis
Autorzy:
Wasilewska, A.
Powiązania:
https://bibliotekanauki.pl/articles/98795.pdf
Data publikacji:
2016
Wydawca:
Politechnika Śląska. Katedra Biomechatroniki
Tematy:
Reumatoidalne Zapalenie Stawów
termowizja
temperatura
rheumatoid arthritis
thermovision
temperature
Opis:
Reumatoidalne Zapalenie Stawów (RZS) jest chorobą o podłożu autoimmunologicznym obejmującą wiele stawów, która objawia się między innymi w postaci hipertermii powierzchni skóry. Celem pracy było zbadanie czynników wpływających na termowizyjny pomiar temperatury stawów pacjentów z RZS. Istotne statystycznie różnice zaobserwowano dla takich czynników jak: wiek, płeć i czas trwania choroby.
Rheumatoid arthritis is a chronic autoimmune disease affecting multiple joints, which manifests itself by hyperthermia of skin surfaces. The aim of the current study was to examine factors that influence thermovisual measurement in RA patients. Statistically significant differences were found for age, gender,and disease duration.
Źródło:
Aktualne Problemy Biomechaniki; 2016, 10; 81-84
1898-763X
Pojawia się w:
Aktualne Problemy Biomechaniki
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Pain and mobility improvement and MDA plasma levels in degenerative osteoarthritis, low back pain, and rheumatoid arthritis after infrared A-irradiation
Autorzy:
Siems, Werner
Bresgen, Nikolaus
Brenke, Rainer
Siems, Renate
Kitzing, Manfred
Harting, Heike
Eckl, Peter
Powiązania:
https://bibliotekanauki.pl/articles/1040373.pdf
Data publikacji:
2010
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
rheumatoid arthritis
infrared
malondialdehyde (MDA)
lipid peroxidation
pain
osteoarthritis
Opis:
Infrared (IR)-A irradiation can be useful in back and musculoskeletal pain therapy. In this study joint and vertebral column pain and mobility were measured during two weeks of IR-A irradiation treatment of patients suffering from degenerative osteoarthritis of hip and knee, low back pain, or rheumatoid arthritis. Additionally, before and after IR-A treatment MDA serum levels were measured to check if MDA variations accompany changes in pain intensity and mobility. Two-hundred and seven patients were divided into verum groups getting IR-irradiation, placebo groups getting visible, but not IR irradiation, and groups getting no irradiation. In osteoarthritis significant pain reduction according to Visual Analogue Scale and mobility improvements occurred in the verum group. Even though beneficial mean value changes occurred in the placebo group, the improvements in the placebo and No Irradiation groups were without statistical significance. In low back pain, pain and mobility improvements (by 35-40%) in the verum group were found, too. A delayed (2nd week) mobility improvement in rheumatoid arthritis was seen. However, pain relief was seen immediately. In patients suffering from low back pain or rheumatoid arthritis, the pain and mobility improvements were accompanied by significant changes of MDA serum levels. However, MDA appears not a sensitive biofactor for changes of the pain intensity in degenerative osteoarthritis. Nevertheless, unaffected or lowered MDA levels during intensive IR-A therapy argue against previous reports on free radical formation upon infrared. In conclusion, rapid beneficial effects of IR-A towards musculoskeletal pain and joint mobility loss were demonstrated.
Źródło:
Acta Biochimica Polonica; 2010, 57, 3; 313-319
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Quality of life and methods of coping with stress depending on the used form of therapy of rheumatoid arthritis treatment
Autorzy:
Jankowska-Polanska, B.
Nawrocka, A.
Uchmanowicz, I.
Rosinczuk, J.
Polanski, J.
Powiązania:
https://bibliotekanauki.pl/articles/1916577.pdf
Data publikacji:
2014
Wydawca:
Uniwersytet Medyczny w Białymstoku
Tematy:
Quality life
SF-36; rheumatoid arthritis
coping with stress
Opis:
Introduction: There are studies, which prove a positive influence of biological drugs on effects of medical therapy but there are few of them, which focus on aspects of quality of life and coping with stress. Purpose: To assess quality of life (QoL) and methods of coping with stress depending on the used form of therapy of rheumatoid arthritis (RA) treatment. Materials and methods: Comparative analysis included 64 patients: I group B – treated with the method of biological agents; II group T - treated according to rheumatologic standards. The study used: Short Form 36 (SF–36)- general questionnaire use for assessment QoL, HAQ (Health Assessment Questionnaire) scale of functional efficiency, Mini-COPE inventory for coping with stress. Results: Assessment of QoL with the use of the SF-36 questionnaire showed low QoL of patients in both groups. Higher QoL was observed in group B in all domains except PF domain where group T got a higher score. Analysis of QoL within total physical and mental health assessment also indicated higher QoL of patients from group B relatively PCS (39.8% vs. 33.5%) and MCS (56.9% vs. 40.9%; p<0.001). Analysis of coping with stress showed that the most common strategies of coping with stress in group B are positive: sense of humour (1.06 vs. 0.61; p=0.008) and planning (1.95 vs. 1.81), positive redefinition (1.59 vs. 1.48), acceptance (2.00 vs. 1.95). Whereas among patients in group T the strategy ‘turn to religion’ prevails (1.44 vs. 0.91; p=0.014). Conclusions: Biological agents favourably affect assessment of QoL and a degree of functional disability in patients with significant intensification of the disease symptoms. In patients treated with biological drugs using positive strategies of coping with stress, and difficult situation is observed. Patients treated with biological drugs show better satisfaction from treatment and fewer unfavourable symptoms resulting from the used therapy.
Źródło:
Progress in Health Sciences; 2014, 4, 2; 102-110
2083-1617
Pojawia się w:
Progress in Health Sciences
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Association between body mass and physical activity with quality of life in patients with rheumatoid arthritis
Autorzy:
Świtała, Anna
Wyszyńska, Justyna
Czerwińska, Kinga
Dereń, Katarzyna
Podgórska-Bednarz, Justyna
Guzik, Agnieszka
Powiązania:
https://bibliotekanauki.pl/articles/454682.pdf
Data publikacji:
2017
Wydawca:
Uniwersytet Rzeszowski. Wydawnictwo Uniwersytetu Rzeszowskiego
Tematy:
body mass index
quality of life
physical activity
rheumatoid arthritis
Opis:
Introduction. Rheumatoid arthritis (RA) is a progressive joint condition that leads to joints destruction and complications in the internal organs and significantly affects the a patient’s functional, physical, psychological and social condition. Over the last few years, research into the quality of life (QoL) in people with chronic disease has been conducted to assess the results of treatment. Aim. The aim of the study was to assess QoL in various areas of life in regards to physical and mental functioning, social relations, and environmental influences in people with RA. Material and methods. The study group (subjects with RA) and the control group (subjects without RA) consisted of 48 people each. Subject age ranged from 19 to 68. In order to assess QoL, the WHOQOL-BREF questionnaire was used, while socio-demographic data were assessed with a questionnaire developed by the authors. Results. QoL in people with RA was lower than that of healthy individuals. The worst QoL was observed in the physical domain. No statistically significant association was found between BMI and QoL. It was found, however, that subjects with RA and a higher level of physical activity had a better QoL than those with a lower level of physical activity. Conclusion. There was no association between the body mass of RA patients and QoL assessment. However, an association was found between the level of physical activity in people with RA and QoL in the physical and environmental domain.
Źródło:
European Journal of Clinical and Experimental Medicine; 2017, 3; 200-205
2544-2406
2544-1361
Pojawia się w:
European Journal of Clinical and Experimental Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Influence of ω-3 polyunsaturated fatty acids on the structure of immunocompetent cell membranes and the parameters of cellular and humoral immunity in children with rheumatoid arthritis
Autorzy:
Yarema, Natalia
Fedortsiv, Olga
Palasiuk, Bohdan
Powiązania:
https://bibliotekanauki.pl/articles/552188.pdf
Data publikacji:
2018
Wydawca:
Stowarzyszenie Przyjaciół Medycyny Rodzinnej i Lekarzy Rodzinnych
Tematy:
rheumatoid arthritis (RA)
fatty acids
immune system
cel membrane
child.
Źródło:
Family Medicine & Primary Care Review; 2018, 1; 78-82
1734-3402
Pojawia się w:
Family Medicine & Primary Care Review
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Vitamin D status in patients with rheumatoid arthritis: a correlation analysis with disease activity and progression, as well as serum IL-6 levels
Autorzy:
Polasik, Kinga
Piotrowska, Ewa
Lipińska, Barbara
Witkowski, Jacek
Bryl, Ewa
Tukaj, Stefan
Powiązania:
https://bibliotekanauki.pl/articles/1038556.pdf
Data publikacji:
2017
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
rheumatoid arthritis
vitamin D deficiency
25(OH)D
IL-6
Opis:
Objectives. Recent epidemiological studies suggested an association between a poor vitamin D [25(OH)D] status, inflammatory mediators, and rheumatoid arthritis (RA). We have recently proposed that pro-inflammatory interleukin 6 (IL-6) may represent a good marker for disease activity of RA. The aim of this study was to investigate the relationship between serum 25(OH)D levels and disease activity, joint damage, as well as serum IL-6 levels in a Polish RA population. Materials and Methods. Serum 25(OH)D levels were measured in 35 female RA patients and 38 age- and gender-matched healthy controls. Statistical correlations between 25(OH)D levels and the disease activity score 28 (DAS 28), joint damage based on the Steinbrocker criteria, as well as serum IL-6 levels were performed. Results. There was no statistically significant difference between levels of 25(OH)D in RA (16.89±8.57 ng/ml) and healthy controls (14.12±7.51 ng/ml), and the vitamin D deficiency (<20 ng/ml) was found in 71.43% of RA patients and 73.68 % of healthy controls. While vitamin D status did not correlate with DAS 28 (r=0.265, p=0.149) and joint damage based on the Steinbrocker criteria (r=0.367, p=0.065), a positive correlation between 25(OH)D and IL-6 (r=0.537, p=0.002) was observed in RA. Conclusion. Although further studies on a larger group of patients will be needed to confirm the data presented here, it seems that hypovitaminosis D is common in the RA patients and middle-aged non-RA healthy women in the Polish population. 25(OH)D levels were similar in the RA patients and age- and gender-matched healthy controls, and were not associated with joint damage and disease activity in patients.
Źródło:
Acta Biochimica Polonica; 2017, 64, 4; 667-670
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Mapowanie pojęć ICNP® na przykładzie procesu pielęgnowania pacjenta z reumatoidalnym zapaleniem stawów
The ICNP® terms cross-mapping on the example of nursing care of patient with rheumatoid arthritis
Autorzy:
Zawidzka, Magdalena
Haor, Beata
Powiązania:
https://bibliotekanauki.pl/articles/1179202.pdf
Data publikacji:
2019-03-25
Wydawca:
Państwowa Uczelnia Zawodowa we Włocławku
Tematy:
proces pielęgnowania
icnp®
reumatoidalne zapalenie stawów
nursing process
rheumatoid arthritis
Opis:
Wstęp. Reumatoidalne zapalenie stawów (RZS) to choroba autoimmunologiczna, wywołująca głównie stany zapalne tkanki łącznej. Jej przebieg związany jest z symetrycznym zajęciem stawów oraz pozastawowymi zmianami, które prowadzą do dysfunkcji wielu narządów. Cel. Celem niniejszej pracy było mapowanie najczęściej występujących u pacjentów z RZS problemów pielęgnacyjnych, działań pielęgniarskich i ich ewaluacji z frazami opisującymi diagnozy, wyniki i interwencje wg ICNP® Materiały i metody. W pracy zastosowano metodę analizy piśmiennictwa poświęconego zagadnieniom opieki nad chorym z RZS oraz mapowanie diagnoz i interwencji przy użyciu słownika ICNP®. Wyniki i wnioski. Zastosowanie klasyfikacji ICNP® pozwala na stosowanie ujednoliconej, referencyjnej terminologii w praktyce pielęgniarskiej. Usprawnia to komunikację oraz umożliwia harmonizację oraz porównywanie danych. Korzystanie z ujednoliconej terminologii zawodowej jest jednym z wyznaczników autonomii zawodu.
Introduction. Rheumatoid arthritis is an autoimmune disease which mainly causes connective tissue inflammation and affects joints.. Its course is related to the symmetrical involvement of joints and non-articular changes that lead to dysfunction of many organs. Aim. The aim of this study was to map the most frequent nursing problems, nursing activities and their evaluation with the phrases describing diagnoses, results and interventions according to ICNP® in RA patients. Material and methods. The study uses the method of analysis of existing literature devoted to the issues of caring for a patient with RA and mapping diagnoses and interventions using the ICNP® vocabulary. Results and conclusion. The use of ICNP® classification allows the use of unified, reference terminology in nursing practice. It facilitates communication and enables harmonization and comparison of data. The use of unified vocational terminology is one of the determinants of the autonomy of the profession.
Źródło:
Innowacje w Pielęgniarstwie i Naukach o Zdrowiu; 2019, 4, 1; 107-119
2451-1846
Pojawia się w:
Innowacje w Pielęgniarstwie i Naukach o Zdrowiu
Dostawca treści:
Biblioteka Nauki
Artykuł
Wyświetlanie 1-15 z 42

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