- Tytuł:
- Detection of damage-recognition proteins from human lymphocytes.
- Autorzy:
-
Łanuszewska, Joanna
Cudak, Anna
Rzeszowska-Wolny, Joanna
Widłak, Piotr - Powiązania:
- https://bibliotekanauki.pl/articles/1044373.pdf
- Data publikacji:
- 2000
- Wydawca:
- Polskie Towarzystwo Biochemiczne
- Tematy:
-
damage recognition
human lymphocytes
damaged DNA-binding proteins
repair capacity - Opis:
- Proteins recognizing and binding to damaged DNA (DDB-proteins) were analyzed in human lymphocytes obtained from healthy donors. Using an electrophoretic mobility shift assay several complexes between nuclear extract proteins and damaged DNA were detected: a complex specific for DNA damaged by N-acetoxy-N-acetylaminofluorene, another complex specific for UV-irradiated DNA, and two complexes specific for DNA damaged by cis-dichlorodiammine platinum. All the detected complexes differed in electrophoretic mobility and possibly contained different proteins. Complexes specific for free DNA ends were also detected in protein extracts from lymphocytes.
- Źródło:
-
Acta Biochimica Polonica; 2000, 47, 2; 443-450
0001-527X - Pojawia się w:
- Acta Biochimica Polonica
- Dostawca treści:
- Biblioteka Nauki