Temat: psyllium - Katalog OPAC zbiorów

Skocz do pozycji: 1.

Tytuł:: FORMULATION AND IN VITRO EVALUATION OF FLOATING TABLETS OF PSYLLIUM HUSK & TRAGACANTH USING SITAGLIPTIN PHOSPHATE AS A MODEL DRUG
Autorzy:: Ghumman, Shazia A.
Andleeb, Sahrish
Bashir, Sajid
Muhammad, Sarfraz R.
Badshah, Munair
Khattak, Majeedullah
Powiązania:: https://bibliotekanauki.pl/articles/895403.pdf
Data publikacji:: 2018-06-30
Wydawca:: Polskie Towarzystwo Farmaceutyczne
Tematy:: sustained release
Release kinetics
Tragacanth
floating tablets
Sitagliptin phosphate
psyllium husk
Opis:: Abstract A novel floating controlled release drug delivery system of Sitagliptin phosphate was formulated in an effort to increase the gastric retention time of the dosage form and thereby increased drug bioavailability. The tablets were prepared by wet granulation method using Psyllium Husk and tragacanth gum as a release retarding polymers and sodium bicarbonate as a gas generating agent. All the designed nine batches of floating tablets were evaluated for physical characteristics viz. weight variation, thickness, content uniformity, hardness, floating capacity, swelling studies. All formulations had floating lag time of less than 1 min and constantly floated for 12 h except F1, F4 and F7 (that dissolved completely in 8 h or less than 8 h). In vitro drug release studies were carried out for 8 h and release mechanism was further evaluated by linear regression analysis, F9 composed of 30% Psyllium Husk, 10% tragacanth gum and 18% sodium bicarbonate sustained the drug release for longer period. The formulations followed first order kinetics, Higuchi drug release kinetics with diffusion as the dominant mechanism of drug release and the release exponent ranged (0.452-0.635) indicating that the drug release from all formulations was by non-Fickian diffusion mechanism. The prepared floating tablets of STP (F9) might be a promising drug delivery system with sustained release action and improved bioavailability.
Źródło:: Acta Poloniae Pharmaceutica - Drug Research; 2018, 75, 3
0001-6837
2353-5288
Pojawia się w:: Acta Poloniae Pharmaceutica - Drug Research
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 2.

Tytuł:: Physical properties of psyllium seed
Autorzy:: Ahmadi, R.
Kalbasi-Ashtari, A.
Gharibzahedi, S.M.T.
Powiązania:: https://bibliotekanauki.pl/articles/24892.pdf
Data publikacji:: 2012
Wydawca:: Polska Akademia Nauk. Instytut Agrofizyki PAN
Tematy:: physical property
psyllium
seed
postharvest technology
Plantago ovata
India
plant cultivation
Opis:: Physical properties ie dimensions, volume, surface area, sphericity, true density, porosity, angle of repose, terminal velocity, static and dynamic friction coefficients on plywood, stainless steel, glass and galvanized iron sheet, force required for initiating seed rupture in horizontal and vertical orientations of psylliumseed at amoisture content of 7.2%(w.b.)were determined.
Źródło:: International Agrophysics; 2012, 26, 1
0236-8722
Pojawia się w:: International Agrophysics
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 3.

Tytuł:: Preliminary researches on sand accumulation in the alimentary canal of recreational riding horses
Wstępne badania nad zapiaszczeniem przewodu pokarmowego koni użytkowanych rekreacyjnie
Autorzy:: Ciesla, A.
Ignor, J.
Przybylowicz, N.
Pikula, I.
Powiązania:: https://bibliotekanauki.pl/articles/44745.pdf
Data publikacji:: 2011
Wydawca:: Zachodniopomorski Uniwersytet Technologiczny w Szczecinie. Wydawnictwo Uczelniane ZUT w Szczecinie
Tematy:: sand accumulation
sand
gastrointestinal tract
intestine
horse
recreational riding
Plantago psyllium
seed
colic
animal disease
Opis:: Six warm-blooded horses in the age of 6 till 16, were researched. The horses were divided into two groups: experimental and testing (each per 3 horses). In the first stage the trial was taken up to estimate the grade (rank) of sand accumulation in the alimentary canal of all horses with using the floatation test. In the second stage the experimental group with the given foragegot the supplement of Plantago Psyllium seeds in the amount of 210 g per horse per day during 7 days. The researches revealed that preventive supplement of Plantago Psyllium seeds three times increases the amount of sand excreted from the alimentary canal. So using the supplement of Plantago Psyllium seeds can prevent the excessive of sand concentration in horses alimentary canal and this way decreases the risk of occurring the intestinal colic diseases – in the matter.
Badaniami objęto 6 koni gorącokrwistych w wieku od 6 do 16 lat. Konie podzielono na grupę doświadczalną i kontrolną (liczące po trzy konie). Badania przeprowadzono w dwóch etapach. W pierwszym etapie podjęto próbę określenia stopnia zapiaszczenia jelit u wszystkich koni z wykorzystaniem testu flotacji. W drugim etapie grupa doświadczalna wraz z zadawaną paszą przyjmowała dodatek nasion babki płesznik w ilości 210 g na konia na dzień przez 7 kolejnych dni. Badania wykazały, że profilaktyczne podawanie koniom nasion babki płesznik trzykrotnie zwiększa ilość piasku wydalanego z przewodu pokarmowego. Stosowanie dodatku nasion Plantago psyllium może więc zapobiegać nadmiernemu gromadzeniu się piasku w przewodzie pokarmowym koni, a tym samym zmniejsza ryzyko wystąpienia schorzeń kolkowych na tym tle.
Źródło:: Acta Scientiarum Polonorum. Zootechnica; 2011, 10, 2
1644-0714
Pojawia się w:: Acta Scientiarum Polonorum. Zootechnica
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 4.

Tytuł:: Preparation of psyllium husk powder based microporous composite scaffolds for tissue engineering
Autorzy:: Poddar, S.
Agarwal, P. S.
Mahto, S. K.
Powiązania:: https://bibliotekanauki.pl/articles/285978.pdf
Data publikacji:: 2018
Wydawca:: Akademia Górniczo-Hutnicza im. Stanisława Staszica w Krakowie. Polskie Towarzystwo Biominerałów
Tematy:: psyllium husk powder
EDC-NHS coupling reaction
microporous scaffolds
hydrogel
freeze-drying
vacuum desiccation
Opis:: This study demonstrates the comparison in the method of fabrication and thus evaluates the potential of psyllium husk powder and gelatin-based composite microporous scaffolds for tissue engineering applications. The scaffold is being prepared in three different ratios of 50:50, 75:25 and 100 (w/w of psyllium husk powder and gelatin, respectively) by employing a suitable cross-linking agent, EDC-NHS, followed drying. We have demonstrated the use and outcomes of two different methods of scaffold drying, i.e., vacuum desiccation along with liquid nitrogen dip and lyophilization. It was concluded from the SEM micrographs that the scaffolds dried under vacuum accompanied with liquid nitrogen exposure exhibited less porous architecture when compared to those prepared using a lyophilizer, that resulted in pores in the range of 60-110 μm. Scaffolds fabricated using the former technique lost porosity and sponge-like characteristics of a scaffold. In spite of the above fact, water retaining capacity and stability in the cell culture of such scaffolds is significant, nearly 40-50% of its initial dry weight. Cell culture experiments support the potential of the scaffolds prepared from different methods of fabrication for its cytocompatibility and suitability for cell growth and proliferation for a substantial duration. Erosion in the porous design of the scaffolds was observed after 14 days via SEM micrographs. It was inferred that freeze-drying is a better technique than vacuum desiccation for scaffold preparation. The present investigation has been conducted keeping in mind the importance of drying a scaffold. Scaffold drying is a necessary step to increase its shelf-life, makes it easy to transport and much importantly, controlling the pore size of the scaffold.
Źródło:: Engineering of Biomaterials; 2018, 21, 147; 2-6
1429-7248
Pojawia się w:: Engineering of Biomaterials
Dostawca treści:: Biblioteka Nauki

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