- Tytuł:
- Wpływ wykonania kochleostomii na zachowanie słuchu – badania na modelu zwierzęcym
- Autorzy:
-
Stanisławek-Sut, Olimpia
Morawski, Krzysztof
Niemczyk, Kazimierz - Powiązania:
- https://bibliotekanauki.pl/articles/1398683.pdf
- Data publikacji:
- 2010
- Wydawca:
- Index Copernicus International
- Tematy:
-
świnka morska
kochleostomia
próg słuchowy - Opis:
- Introduction: To assess an effect of cochleostomy on hearing threshold in guinea pigs. Material and methods: The authors performed animal experiments using fi ve 3-month-old guinea pigs. Before experiment hearing threshold were evaluated. Surgery involved access to the temporal bone by a post-auricular incision. After a wide opening of the bulla cochleostomy was created (10 000 turn/min, diamond bur of 0,8 mm diameter). Hearing threshold was identifi ed on the basis of presence of wave V in auditory brainstem responses (ABR) for click and frequency-specifi c stimulation. Also morphology and latency changes for wave V for this stimulation was assesed. Hearing status was evaluated before, just after and 1-, 2-, and 4-weeks after surgery. For surgical procedure and ABR examination all animals were anesthetized with an intramuscular injection of ketamine (50 mg/kg) mixed with xylazine (9 mg/kg) in the supplemental doses. After surgery the animal was treated by antibioticoterapy for 3 days – Enrofl oksacyna 0,3 ml subcutaneouly and analgesic – Tolfedine 0,05 mg in second day. Results: Four week observation of ABR morphology and hearing thresholds for click and frequency-specifi c stimulation of 100 dB SPL intensity showed only temporary changes confi rming that cochleostomy did not affect cochlear function. Conclusions: The correctly performed cochleostomy in guinea pigs did not affect persistently the cochlear function indicating that such an option of CI electrode insertion in patients is safe.
- Źródło:
-
Polish Journal of Otolaryngology; 2010, 64, 7; 17-21
0030-6657
2300-8423 - Pojawia się w:
- Polish Journal of Otolaryngology
- Dostawca treści:
- Biblioteka Nauki
Artykuł