- Tytuł:
-
Synteza i aktywność biologiczna pochodnych pirolo[2,3-d]pirydazyny
Synthesis and biological activity of pyrrolo[2,3-d]pyridazine derivatives - Autorzy:
-
Redzicka, A.
Tylińska, B. - Powiązania:
- https://bibliotekanauki.pl/articles/171583.pdf
- Data publikacji:
- 2016
- Wydawca:
- Polskie Towarzystwo Chemiczne
- Tematy:
-
pochodne pirolo[2,3-d]pirydazyny
aktywność biologiczna
synteza
pyrrolo[2,3-d]pyridazine derivatives
biological activity
synthesis - Opis:
- Pyrrolo[2,3-d]pyridazines are one of the four structural isomers of the bicyclic ring system containing pyrrole moiety condensed with a pyridazine ring. This review presents most of the literature data about synthetic pyrrolo[2,3-d]pyridazine derivatives and their biological activity. These 5,6-diazaindole analogues were first synthesized by Fischer et. al. in 1928. Compounds containing the pyrrolo[2,3-d] pyridazine scaffold can be synthesized from different substrates, but the syntheses may be classified into two main categories: annulation of pyrrole ring on to pyridazine derivatives or annulation of pyridazine ring on to pyrrole derivatives. Pyrrolo[2,3-d]pyridazine derivatives have attracted considerable interest, owing to diverse biological activities. Most of them have been studied as antitumor and antiviral. Pyrrolo[2,3-d]pyridazines can also be used as acid pump antagonist.
- Źródło:
-
Wiadomości Chemiczne; 2016, 70, 3-4; 141-161
0043-5104
2300-0295 - Pojawia się w:
- Wiadomości Chemiczne
- Dostawca treści:
- Biblioteka Nauki
Artykuł