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    Wyświetlanie 1-5 z 5
    Tytuł:
    New experimental model of chronic traumatic osteomyelitis for lower jaw
    Autorzy:
    Pohodenko-Chudakova, I. O.
    Powiązania:
    https://bibliotekanauki.pl/articles/285671.pdf
    Data publikacji:
    2008
    Wydawca:
    Akademia Górniczo-Hutnicza im. Stanisława Staszica w Krakowie. Polskie Towarzystwo Biominerałów
    Tematy:
    osteomyelitis
    chronic traumatic
    lower jaw
    Źródło:
    Engineering of Biomaterials; 2008, 11, no. 77-80; 1-2
    1429-7248
    Pojawia się w:
    Engineering of Biomaterials
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Novel strategies for aminoglycoside antibiotic delivery in skeletal tissues - a review
    Autorzy:
    Posadowska, U.
    Pamuła, E.
    Powiązania:
    https://bibliotekanauki.pl/articles/285107.pdf
    Data publikacji:
    2012
    Wydawca:
    Akademia Górniczo-Hutnicza im. Stanisława Staszica w Krakowie. Polskie Towarzystwo Biominerałów
    Tematy:
    aliphatic polyesters
    biopolymers
    gentamicin administration
    microparticles
    osteomyelitis
    Opis:
    This paper reviews recent advances concerning antibiotic-loaded microparticles application in osteomyelitis treatment. We discuss different methods utilized for microparticles' preparation, i.e. double emulsification, simple emulsification and spray drying. Materials comprised of sphere-shaped matrices are also presented. We point out that the most commonly used microsphere-building components are biodegrad¬able aliphatic polyesters such as poly(lactide-co-glicolide) PLGA, poly(sebacic-ricinoleic-ester-anhydride) P(SA-RA) and poly(lactic-co-hydroxymethyl glycolic acid) PLHMGA. Biopolymers like gelatin, starch or chitosan are also applied as antibiotic carriers. Relationship between preparation method, type of material and its crosslinking degree, microparticles' immobilization steps and the amount of loaded antibiotic are reported as the main factors controlling release rate of drugs in osteomyelitis treatment. And finally, several approaches to produce injectable formulations as well as implantable three dimensional scaffolds with the use of microparticles are described. All in all, this proves that antibiotic-loaded microspheres are a versatile form of biomaterials in osteomyelitis therapy.
    Źródło:
    Engineering of Biomaterials; 2012, 15, 114; 3-7
    1429-7248
    Pojawia się w:
    Engineering of Biomaterials
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Comparative study on the usefulness of Gentamycin-containing collagen implants in the treatment of patients with osteitis and osteomyelitis of the craniofacial skeleton
    Autorzy:
    Zawadzki, Paweł J.
    Perkowski, Konrad
    Kotlarski, Michał
    Pietruczuk-Padzik, Anna
    Chomicz, Lidia
    Powiązania:
    https://bibliotekanauki.pl/articles/989759.pdf
    Data publikacji:
    2017
    Wydawca:
    Instytut Medycyny Wsi
    Tematy:
    comparative study
    gentamycin-containing collagen treatment patients
    osteomyelitis
    craniofacial skeleton
    Opis:
    Introduction and objective. A reduction in incidences of peri-surgical complications due to infections is achieved by antibiotic prophylaxis The objective of the study was to assess the usefulness of gentamycin-containing collagen implants (GCCI) in the treatment of patients with osteitis and osteomyelitis of the craniofacial skeleton. Materials and method. The retrospective study included 103 patients with osteitis and osteomyelitis. 54 patients were treated intra-operatively with GCCI (Garamycin, EusaPharma, Europe). 49 patients were treated according to standard procedures. Light microscopy and in vitro culture techniques were applied for bacteria specific identification, and to investigate the resistance of detected microbiota to antibiotics. Patients received one dose of antibiotic pre-operatively. Post-operative antibiotic treatment was administered individually, according to clinical course and microbiological tests. The patients were followed-up on days 3, 7 and 14 after discharge for local complications; radiographic follow-up was performed 3, 6 and 12 months after surgery. Results. The course of post-operative antibiotic therapy was shorter in GCCI patients than in the control group (median 1 vs. 7 days); they also required shorter hospitalization (median 3 vs. 4 days). Implantation of GCCI significantly reduced the incidence of local complications (OR 0.30, 95%CI 0.11–0.83, p<0.0001), independently of the use of postoperative antibiotic therapy. On follow-up after 3–12 months, all patients presented with good soft tissue and bone healing. Conclusions. The results of this comparative study advocate the use of GCCI in osteomyelitis of various origin in oral and maxillofacial surgery, as they seemed to reduce the incidence of local complications, shorten antibiotic administration time and hospital stay.
    Źródło:
    Annals of Agricultural and Environmental Medicine; 2017, 24, 2
    1232-1966
    Pojawia się w:
    Annals of Agricultural and Environmental Medicine
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Cat Scratch Disease in a 1.5-year-old girl - case report
    Autorzy:
    Karski, J.
    Matuszewski, L.
    Okoński, M.
    Pietrzyk, D.
    Karska, K.
    Załuski, M.
    Powiązania:
    https://bibliotekanauki.pl/articles/2081702.pdf
    Data publikacji:
    2018
    Wydawca:
    Instytut Medycyny Wsi
    Tematy:
    Cat Scratch Diseases
    osteolisis
    osteomyelitis
    Opis:
    Introduction. The paper is a case report presenting Cat Scratch Disease (CSD) in a 1.5-year- old girl. Bartoneloses, including CSD, are a group of infectious diseases which are rarely detected, therefore there are no statistical data concerning the aetiology, and the incidence of CSD noted in Poland is low in comparison with other European countries. Objective. The purpose of the paper is to discuss several problems related to CSD. Materials and method. A 1.5-year-old girl who was seen in hospital for the sparing use of her left arm when crawling. X-rays showed osteolytic lesions which radiologists described as multi-ocular cyst or infection. As neither clinical examination nor laboratory investigations found pathological signs, the patient was followed-up on an ambulant basis. Repeated x-ray taken 4 weeks later showed increased periosteal proliferation accompanied by pain. The baby was admitted to the Clinic but additional investigations found no pathologies. The baby was consulted by a rheumatologist and haematologist; however, they did not facilitate a definitive diagnosis. As the baby developed, because of a thickening of the soft tissues on the dorsal side of the distal epiphisis in the forearm the doctors decided to inspect the condition operatively. Macroscopic examination found brownish granulated tissue. Suction drainage was inserted and a tissue sample was tested for aerobic and anaerobic bacteria, tuberculosis and borelliosis. The test results were negative. The baby was in good condition, was not pyrexial and suffered from less pain. The diagnostics was further expanded and the baby tested for yersinia, chlamydia, tuberculosis and bartonella, i.e. CSD. The postoperative wound healed soon and radiological bony lesions began to resolve. After a month, we received a positive bartonella test result, the baby tested positively for Bartonella henselae IgG class, which confirmed past or active infection of CSD. A repeated test for B. henselae taken 6 months later showed a lower level of antibodies. Conclusions. It should be remembered that CSD, which is an extremely rare infection, can be diagnosed despite mediocre clinical and radiological manifestations. Thus, in the case of infections of unexplained aetiology and mediocre manifestations diagnostics should include testing for Bartonella henselae.
    Źródło:
    Annals of Agricultural and Environmental Medicine; 2018, 25, 2; 345-348
    1232-1966
    Pojawia się w:
    Annals of Agricultural and Environmental Medicine
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Review of contemporary knowledge of Osteomyelitis diagnosis
    Autorzy:
    Michno, Adrian
    Nowak, Anna
    Królicki, Leszek
    Powiązania:
    https://bibliotekanauki.pl/articles/1157714.pdf
    Data publikacji:
    2018
    Wydawca:
    Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
    Tematy:
    ct
    inflammation
    mri
    osteomyelitis
    pet
    scintigraphy
    Opis:
    Osteomyelitis is an inflammation of the bone caused by a pyogenic organism that affects about 13 and 90 out of every 10 000 children and adults respectively. Symptoms of osteomyelitis are often nonspecific, including fever, chills, fatigue, lethargy or irritability. The major cause of bone infections is Staphylococcus aureus, however other pathogens may also lead to osteomyelitis. Due to nonspecific clinical picture and pathogenesis of osteomyelitis, the diagnostic process may be difficult, especially in the chronic form of the disease. It is essential to recognize this interdisciplinary malady and carry out a diagnostic process of osteomyelitis. The physical examination is extremely important in recognizing the osteomyelitis. The doctor ought to note scars, wound, erythema or oedema over the involved area and ask for systemic symptoms and bone pain. Subsequently, a physician should commission laboratory tests and microbiological examination, in order to verify the pathogenic organism, which must be treated with antibiotics. To put the right diagnosis, other studies such as plain radiography, magnetic resonance imaging, computed tomography, nuclear modalities must be performed. In differential diagnosis, other diseases such as bone tumours, fractures, Charcot Arthropathy, soft tissue infection, gout, osteonecrosis, and SAPHO syndrome must be considered. When both the diagnosis and the differential diagnosis is done, antimicrobial therapy is a treatment of choice together with an eventual surgical treatment which may be essential in certain cases. The differential diagnosis in patients with bone pain and systemic symptoms may be sometimes misleading and complicated. It is important, both for physician and patient, to recognize, carry out diagnostic and differential process in a way that a proper treatment shall be applied as soon as possible in order to avoid its complications, including even in an amputation of the affected limb.
    Źródło:
    World Scientific News; 2018, 92, 2; 272-282
    2392-2192
    Pojawia się w:
    World Scientific News
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
      Wyświetlanie 1-5 z 5

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