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    Tytuł:
    Biomonitoring and biomarkers of organophosphate pesticides exposure - state of the art
    Autorzy:
    Kapka-Skrzypczak, L.
    Cyranka, M.
    Skrzypczak, M.
    Kruszewski, M.
    Powiązania:
    https://bibliotekanauki.pl/articles/49859.pdf
    Data publikacji:
    2011
    Wydawca:
    Instytut Medycyny Wsi
    Tematy:
    biomonitoring
    biomarker
    organophosphate pesticide
    pesticide exposure
    human organism
    health risk
    exposure risk
    Źródło:
    Annals of Agricultural and Environmental Medicine; 2011, 18, 2
    1232-1966
    Pojawia się w:
    Annals of Agricultural and Environmental Medicine
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Time and temperature dependent sorption behaviour of dimethoate pesticide in various Indian soils
    Autorzy:
    Rani, S.
    Sud, D.
    Powiązania:
    https://bibliotekanauki.pl/articles/25458.pdf
    Data publikacji:
    2014
    Wydawca:
    Polska Akademia Nauk. Instytut Agrofizyki PAN
    Tematy:
    organophosphate pesticide
    dimethoate
    pesticide
    time
    temperature
    sorption
    isotherm
    kinetics
    thermodynamics
    soil
    soil contamination
    Opis:
    Experiments were conducted to study the sorption behaviour of dimethoate in three Indian soils at different temperatures. A kinetic study showed that adsorption equilibrium was reached within 15 h at different initial levels of pesticide concentration. Applicability of the pseudo second order kinetic model suggested that the adsorption process was complex and several mechanisms were involved. The Freundlich model explained the adsorption behaviour adequately and the isotherms were of S-type. The adsorption process was found to be strongly affected by temperature. The Gibbs free energy change, ΔGº values (from -15.81 to -16.60 kJ mol-1) indicated that the process was spontaneous and exothermic in nature. The change in enthalpy of adsorption, ΔH° values (from -17.729 to -21.539 kJ mol-1) suggested that relatively weak H-bond forces were the main driving forces for adsorption. Desorption was found to be concentration- and temperature-depen- dent with higher desorption occurring at higher temperature and concentration levels. The results signify the importance of temperature in controlling the mobility of dimethoate in water bodies.
    Źródło:
    International Agrophysics; 2014, 28, 4
    0236-8722
    Pojawia się w:
    International Agrophysics
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Organophosphate pesticide exposure and dialkyl phosphate urinary metabolites among chili farmers in Northeastern Thailand
    Autorzy:
    Taneepanichskul, N.
    Norkaew, S.
    Siriwong, W.
    Siripattanakul-Ratpukdi, S.
    Perez, H.L.M.
    Robson, M.G.
    Powiązania:
    https://bibliotekanauki.pl/articles/875473.pdf
    Data publikacji:
    2014
    Wydawca:
    Narodowy Instytut Zdrowia Publicznego. Państwowy Zakład Higieny
    Tematy:
    organophosphate pesticide
    pesticide exposure
    urinary metabolite
    chili
    plant cultivation
    farmer
    skin sample
    air sample
    urine sample
    Thailand
    Opis:
    Background. Chlorpyrifos and profenofos are organophosphate pesticides (OPPs), we studied exposure and urinary metabolites in an agricultural area in the northeastern of Thailand during the chili-growing season (March - April) in 2012. Objective. This study was designed to assess pesticide exposure concentration through dermal and inhalation pathways and to find and depict a relationship between urinary metabolites and means of exposure. Materials and methods. To estimate the pesticides exposure concentration, dermal wipes (hand, face, and feet), dermal patches and air samples were collected from 38 chili farmers. The morning void of pre and post application urine samples was an indicator of biological monitoring in the study which derived from 39 chili farmers. Results. Chlorpyrifos and profenofos residues were detected on dermal patches, face wipes, and hand wipe samples, while no significant residues were found on the feet. Using a personal air sampling technique, all air samples detected pesticide residues. However, significant correlation between dermal pesticide exposure concentration and inhalation was not found (p>0.05). For urinary metabolite levels, there was a relationship between the first pre application morning void and post application morning void (p<0.05); similar to the association between the first pre application morning void and the second post application morning void (p<0.05). The main relationship between pesticide exposure and urinary metabolite was found to have been relevant to dermal exposure (r= 0.405; p<0.05). Conclusions. The results of this study could suggested that public health education training programs, including the use of appropriate personal protective equipment (PPE), should be offered for the chili growing farmers in order to improve their ability to properly use pesticides.
    Wprowadzenie. Chlorpiryfos i profenofos należą do pestycydów fosforoorganicznych (OPPs) stosowanych w rolnictwie, dlatego narażenie na te związki badano w północnowschodniej Tajlandii w okresie uprawy chili (marzec – kwiecień) w 2012 roku. Cel. Celem badania była ocena narażenia na pestycydy przez skórę i drogi oddechowe oraz zbadanie zależności pomiędzy stężeniami metabolitów w moczu a drogą narażenia. Materiał i metoda. Do oceny wielkości narażenia wykorzystano wymazy z rąk, twarzy i stóp i naskórne plastry absorpcyjne oraz próbki powietrza pobierane za pomocą indywidualnych próbników u 39 rolników uprawiających chili. Wyniki. Pozostałości chlorpiryfosu i profenofosu stwierdzano na plastrach absorpcyjnych, wymazach z twarzy i rąk, podczas gdy w wymazach ze stóp nie stwierdzano znaczących ilości tych pestycydów. We wszystkich próbkach powietrza stwierdzono obecność pestycydów. Jednakże, nie wykazano znaczącej korelacji pomiędzy wielkością narażenia przez skórę i drogi oddechowe (p>0.05). W przypadku poziomów metabolitów w moczu, wykazano zależność pomiędzy poziomami metabolitów w moczu przed i po pierwszym zabiegu wykonywanym rano (p<0.05). Zależność pomiędzy narażeniem na pestycydy a stwierdzanymi metabolitami w moczu wynikała z narażenia przez skórę (r= 0.405; p<0.05). Wnioski. Wyniki niniejszych badań mogą sugerować potrzebę wprowadzenia programów edukacyjnych z zakresu zdrowia publicznego, uwzględniających stosowanie przez hodowców chili odpowiedniego sprzętu ochrony osobistej, w celu poprawy możliwości właściwego stosowania pestycydów.
    Źródło:
    Roczniki Państwowego Zakładu Higieny; 2014, 65, 4
    0035-7715
    Pojawia się w:
    Roczniki Państwowego Zakładu Higieny
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    An association between organophosphate pesticides exposure and Parkinsonism amongst people in an agricultural area in Ubon Ratchathani Province, Thailand
    Autorzy:
    Norkaew, S.
    Lertmaharit, S.
    Wilaiwan, W.
    Siriwong, W.
    Perez, H.M.
    Robson, M.G.
    Powiązania:
    https://bibliotekanauki.pl/articles/873417.pdf
    Data publikacji:
    2015
    Wydawca:
    Narodowy Instytut Zdrowia Publicznego. Państwowy Zakład Higieny
    Tematy:
    organophosphate pesticide
    human exposure
    human disease
    cholinesterase activity
    Parkinson's disease
    agricultural area
    Ubon Ratchathani province
    Thailand
    Opis:
    Background. Parkinson’s disease (PD) is a ubiquitous disease. However, PDs prevalence in the population of agricultural communities lacks understanding and there has been no epidemiological study on the association between pesticides exposure factors and risk for PD. Objective. To investigate the potential association between organophosphate pesticides exposure and Parkinsonism by using a screening questionnaire in agricultural areas. Material and Methods. Ninety elderly people living in agricultural areas participated in a cross-sectional study conducted at Tambon Hua-Rua Health Promoting Hospital in April 2014. Screening questionnaires for Parkinson’s disease, Test-mate ChE (Model 400) for blood cholinesterase (ChE) levels of both blood enzymes erythrocyte cholinesterase (AChE), and plasma cholinesterase (PChE) were used as measurement tools. Descriptive statistics for frequencies and percentage distributions were used primarily to summarize and describe the data. Sensitivity, specificity, positive and negative predictive values were calculated. Results. The age range of the participants was 50 to 59 years old, with an average age of 53.9+2.87 years. The majority of the participants were female (62.2%), 82.2% of respondents were farmers. Most of participants (76.7%) reported that they applied insecticides in their farms. Ninety persons participated and completed the 11-item questionnaire. Of these, 17 (18.9%) felt that they lost balance when turning or that they needed to take a few steps to turn right around and 16.7% of participants indicated that they felt the need to move slowly or stiffly. The study found the prevalence of abnormal AChE levels was 28.9% (95%CI=19.81-39.40) and 17.8% of PChE levels (95%CI=10.52-27.26). To predict Parkinsonism, AChE, and PChE level, with a cutoff score of 5 or higher there had to be a sensitivity of 0.31, specificity of 1.00, positive predictive value (PPV) of 1.00 and negative predictive value (NPV) of 0.78 for AChE. While PChE, the score value of 5 or more had a sensitivity of 0.19, specificity of 0.93, PPV of 0.38 and NPV of 0.84. Conclusion. This study described an association between pesticides exposure and Parkinsonism. The questionnaire appears to be useful for Thai agriculturists as a screening tool for Parkinsonism and cholinesterase levels regarding to pesticides exposure.
    Źródło:
    Roczniki Państwowego Zakładu Higieny; 2015, 66, 1
    0035-7715
    Pojawia się w:
    Roczniki Państwowego Zakładu Higieny
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Association between blood cholinesterase activity, organophosphate pesticide residues on hands, and health effects among chili farmers in Ubon Ratchathani Province, northeastern Thailand
    Autorzy:
    Nganchamung, T.
    Robson, M.G.
    Siriwong, W.
    Powiązania:
    https://bibliotekanauki.pl/articles/875443.pdf
    Data publikacji:
    2017
    Wydawca:
    Narodowy Instytut Zdrowia Publicznego. Państwowy Zakład Higieny
    Tematy:
    blood
    cholinesterase activity
    organophosphate pesticide
    pesticide residue
    hand
    healthy effect
    human health
    farmer
    chili
    Ubon Ratchathani province
    Thailand
    Opis:
    Background. Use of pesticides has been documented to lead to several adverse health effects. Farmers are likely to be exposed to pesticides through dermal exposure as a result of mixing, loading, and spraying. Organophosphate pesticides (OPs) are widely used in most of the agricultural areas throughout Thailand. OPs are cholinesterase inhibitors and blood cholinesterase activity is used as a biomarker of OP effects. Objective. This study aims to determine the association between blood cholinesterase activity and organophosphate pesticide residues on chili farmer’s hands and their adverse health effects. Materials and Methods. Ninety chili farmers directly involved with pesticide applications (e.g. mixing, loading, spraying) were recruited and were interviewed face to face. Both enzymes, erythrocyte acetylcholinesterase (AChE) and plasma cholinesterase (PChE), were tested with the EQM Test-mate Cholinesterase Test System (Model 400). Hand wipe samples were used for collecting residues on both hands and OP residues for chlorpyrifos and profenofos were quantified using gas chromatography equipped with a flame photometric detector (GC-FPD). Results. The average activity (±SD) of AChE and PChE was 2.73 (±0.88) and 1.58 (±0.56) U/mL, respectively. About 80.0% of the participants had detectable OP residues on hands. The median residues of chlorpyrifos and profenofos were found to be 0.02 and 0.03 mg/kg/two hands, respectively. Half of participants reported having some acute health symptoms within 48 hours after applying pesticides. When adjusted for gender, number of years working in chili farming, and frequency of pesticide use, AChE activity (Adjusted OR = 0.03, 95%CI: 0.01-0.13) and detected OP residues on hands (Adjusted OR = 0.15, 95%CI: 0.02-0.95) were significantly associated with having health effects, but no significant association was found in PChE activity (Adjusted OR = 2.09, 95%CI: 0.63-6.99). Conclusions. This study suggests that regular monitoring for blood cholinesterase and effective interventions to reduce pesticide exposure to prevent health effects should be provided to chili farmers.
    Źródło:
    Roczniki Państwowego Zakładu Higieny; 2017, 68, 2
    0035-7715
    Pojawia się w:
    Roczniki Państwowego Zakładu Higieny
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
      Wyświetlanie 1-5 z 5

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