Temat: oral cavity cancer - Katalog OPAC zbiorów

Skocz do pozycji: 1.

Tytuł:: VDR gene single nucleotide polymorphisms and their association with risk of oral cavity carcinoma
Autorzy:: Małodobra-Mazur, Małgorzata
Paduch, Agnieszka
Lebioda, Arleta
Konopacka, Maria
Rogoliński, Jacek
Szymczyk, Cezary
Wierzgoń, Janusz
Maciejewski, Adam
Chmielik, Ewa
Jonkisz, Anna
Półtorak, Stanisław
Dobosz, Tadeusz
Powiązania:: https://bibliotekanauki.pl/articles/1039670.pdf
Data publikacji:: 2012
Wydawca:: Polskie Towarzystwo Biochemiczne
Tematy:: VDR gene
SNP
oral cavity cancer
Opis:: Vitamin D3 (1,25(OH)2D3 (1,25-dihydroxyvitamin D3)) is a hormone playing a crucial role in numerous biological processes in the human body, including induction and control of cell proliferation and differentiation. Numerous data relate the vitamin D3 level with various types of cancer. It has been suggested that SNPs in the vitamin D3 receptor (VDR) gene might influence both the risk of cancer occurrence and cancer progression. The aim of this study was to search for genetic correlations between individual SNPs in the VDR gene and the risk of oral cavity carcinoma. Two SNPs were selected based on the literature and our previous results. Seventy-three patients with squamous cell carcinoma of the head and neck and one hundred control subjects were investigated. Two SNPs in the VDR gene were genotyped in minisequencing reactions followed by capillary electrophoresis. Hardy-Weinberg equilibrium (HWE), the χ2 test and logistic regression were used for statistical analysis. The SNP rs2238135 in the VDR gene displayed statistical differences in frequency between the tested groups (p=0,0007). Furthermore, the G/C genotype of the rs2238135 in the VDR gene was characterized by a 3.16 fold increased risk of oral cavity carcinoma. The obtained results provide evidence for a genetic association between rs2238135 in the VDR gene and the occurrence and risk of oral cavity cancer.
Źródło:: Acta Biochimica Polonica; 2012, 59, 4; 627-630
0001-527X
Pojawia się w:: Acta Biochimica Polonica
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 2.

Tytuł:: Fungi of the genus Rhodotorula isolated from the oral cavity of oncologic patients with colorectal cancer
Autorzy:: Troska, Piotr
Sucharzewska, Ewa
Dynowska, Maria
Ejdys, Elżbieta
Powiązania:: https://bibliotekanauki.pl/articles/972215.pdf
Data publikacji:: 2017
Wydawca:: Polskie Towarzystwo Parazytologiczne
Tematy:: Rhodotorula
oral cavity
enzymes
colorectal cancer
Opis:: This paper concerns the frequency of occurrence and enzymatic activity of fungi of the genus Rhodotorula isolated from the oral cavity of patients with colorectal cancer. Swabs from the oral cavity were subjected to standard mycological diagnostic procedures; enzymatic activity of the fungi was evaluated using and API Zym test by BioMereux. The fungi of the genus Rhodotorula were noted in 22.5% positive isolates originating from women and 25.7% positive isolates originating from men. They included mono-species isolates of: Rh. glutinis, Rh. minuta, Rh. mucilaginosa and two-species isolates: Rh. minuta + Candida dubliniensis, Rh. mucilaginosa + C. albicans and Rh. mucilaginosa + Saccharomyces cerevisiae. The enzymatic activity of the isolated fungi was evaluated as high and very high in the case of acidic and alkaline phosphatase, esterase lipase, lipase, as well as leucine, valine and cysteine arylamidase. The highest values were determined in Rh. mucilaginosa with co-occurrence of C. albicans and Rh. minuta with co-occurrence of C. dubliniensis. In the ontosphere of oncologic patients, the increasingly frequent appearance of the species of fungi with high and very high enzymatic activity indicates the progressing risk posed by opportunistic forms, which includes Rhodotorula species.
Źródło:: Annals of Parasitology; 2017, 63, 1; 57-62
0043-5163
Pojawia się w:: Annals of Parasitology
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 3.

Tytuł:: Analysis of risk factors for oral cavity and oropharynx cancer in the authors’ own material
Autorzy:: Nowosielska-Grygiel, Joanna
Owczarek, Kalina
Bielińska, Marzena
Wacławek, Magdalena
Olszewski, Jurek
Powiązania:: https://bibliotekanauki.pl/articles/1398310.pdf
Data publikacji:: 2017
Wydawca:: Index Copernicus International
Tematy:: risk factors
oral cavity
oropharynx cancer
Opis:: Introduction: The aim of the study was to analyse the risk factors for oral cavity and oropharynx cancer in peopled examined under the Head and Neck Cancer Awareness Week in 2016, Lodz. Material and methods. In Lodz, 21st September 2016, under the Head and Neck Cancer Awareness Week, 106 people, including 67 women aged 29–77 and 39 men aged 23–84, underwent preventive examinations in the hospital department. Prior to the laryngological examination, the patients were asked to answer questions that referred to their education, medical case history, symptoms, smoking habits with the number of cigarettes per day, alcohol intake, the number of lifetime sexual partners, oral sex engagement, incidents of head and neck cancer in the family history. Results: The major part of the examined patients were women and men with the secondary and high level of education, 47,76% and 35,82%, and 58,97% and 35,91% respectively. The patients were informed by mass media about the planned preventive medical examinations – 80,60% women and 79,49% men. The most common symptoms reported by women were: hoarse voice in 61,19% cases, dysphagia in 32,84% cases and burning sensation and/or pain in the oral cavity in 29,85% cases. The examined male patients mainly showed hoarse voice (46,15%), other symptoms (43,59%) and dysphagia (25,64%). 28,35% women and 28,20% men smoked cigarettes, while passive smokers were 22,38% and 25,64% respectively. Alcohol consumption was reported by 67,16% women and 82,05% men, rather occasionally. Having oral sex was noted in 25,37% women and 38,46% men, mostly with multiple sexual partners. Among the studied patients, 13,43% women and 5,12% men suffered from malignant cancer, including 2,98% women and 2,56% men who reported head and neck carcinoma in the medical interview. On the basis of the interview and ENT examination, 11,94% women and 17,94% men were qualified for the extended oncological diagnostics. Conclussion. The Fourth Head and Neck Cancer Awareness Week shows the increased interest in preventive screening, especially oncological screening, and thus the necessity of such preventive activities in the future.
Źródło:: Polish Journal of Otolaryngology; 2017, 71, 2; 23-28
0030-6657
2300-8423
Pojawia się w:: Polish Journal of Otolaryngology
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 4.

Tytuł:: Retrospective evaluation of risk factors for oral cavity and oropharynx cancers in patients under the program of head and neck cancers prevention
Autorzy:: Kowalski, Andrzej
Olszewski, Jurek
Zielińska-Bliźniewska, Hanna
Powiązania:: https://bibliotekanauki.pl/articles/1397748.pdf
Data publikacji:: 2019
Wydawca:: Index Copernicus International
Tematy:: Head and Neck Cancer Prophylaxis Program
oral cavity
oropharynx cancer
risk factors
Opis:: Introduction: The aim of the study was to analyze the risk factors for oral cavity and pharyngeal cancer in people examined under the Head and Neck Cancer Prophylaxis Program. Material and methods: The study was conducted in a total of 300 patients, including 186 women and 114 men, as part of the Head and Neck Cancer Prevention Program in 2014–2018. Before the laryngological examination, the patients completed a demographic and medical questionnaire regarding the risk factors of head and neck cancer, including education, reported disease symptoms, smoking addiction, number of cigarettes smoked daily, alcohol consumption, frequency of visits in a dental office, oral hygiene measures, number of sexual partners, oral sex, family medical history of head and neck cancer. Results: The subjects reported the following symptoms: hoarseness 43.33%, difficulty swallowing 21.33%, pain or mouth burning 20.33% and other symptoms were observed in 46.33%. The main dental symptoms were: bleeding from the gums during teeth brushing in 48.89%, dry mouth 45.56%. Currently 20.33% of respondents smoke, whereas 54% of patients smoked in the past. In the analyzed material, the majority (80%) consumed alcoholic beverages. 27.67% of respondents admitted having oral sex, including 24.73% of women and 32.46% of men. After performing the extended diagnostics, the tumor was found in 10% of the subjects. C onclusions: Statistical significance of differences was found: between hoarseness and alcohol consumption, both in women and in men, between hoarseness and smoking in women, between difficulty in swallowing and smoking in women, between burning/pain in the mouth and smoking in men, between hoarseness and the cultivation of oral sex in men, between the difficulty of swallowing and the practice of oral sex in the studied men and between burning/pain in the oral cavity and the occurrence of malignancy.
Źródło:: Polish Journal of Otolaryngology; 2019, 73, 6; 24-31
0030-6657
2300-8423
Pojawia się w:: Polish Journal of Otolaryngology
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 5.

Tytuł:: Acid aspartate proteinase activity in fungal strains isolated from the oral cavity of patients with neoplasms
Autorzy:: Rozga, A.
Kurnatowska, A.J.
Loga, G.
Raczynska-Witonska, G.
Powiązania:: https://bibliotekanauki.pl/articles/841105.pdf
Data publikacji:: 1998
Wydawca:: Polskie Towarzystwo Parazytologiczne
Tematy:: endopeptidase
enzyme
cancer
Candida albicans
fungi
exopeptidase
oral cavity
proteolytic enzyme
patient
pathogenicity
fungal strain
acid aspartate proteinase
Candida
Źródło:: Annals of Parasitology; 1998, 44, 3
0043-5163
Pojawia się w:: Annals of Parasitology
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 6.

Tytuł:: Difficulties associated with the diagnosis of mycosis of the oral cavity and throat in chronic lymphocytic leukemia (CLL)
Autorzy:: Kaczmarczyk, D.
Morawiec-Sztandera, A.
Niedźwiecka, I.
Kurnatowski, P.
Powiązania:: https://bibliotekanauki.pl/articles/2143364.pdf
Data publikacji:: 2011
Wydawca:: Polskie Towarzystwo Parazytologiczne
Tematy:: diagnosis
mycosis
oral cavity
throat
chronic lymphocytic leukemia
fungal infection
disease risk
fungi
cancer formation
neoplastic process
treatment
human disease
disease symptom
immunodeficiency
prevalence
Opis:: Cases of fungal infections are being encountered more often in clinical practice. The factors associated with a high risk of mycoses include, among others, corticosteroidotherapy, the administration antibiotics with wide spectrum of antibacterial properties, neutropenia, neoplasms. Fungi may play a role in cancer formation, may act as a complication in the course of treatment, and may mimic a neoplastic process by giving a similar clinical picture. In the case of fungal throat infection, patients complain of increased body temperature, a general feeling of weakness, malaise, headache, spontaneous pain intensifying during swallowing, a feeling of an obstacle in the throat or a cough. A physical examination may reveal congestion of the mucosa followed by a unilateral crater ulceration often covered with fat, as well as a thick coating, which is accompanied by foetor ex ore. The submandibular and neck lymph nodes are often greatly enlarged and painful. These symptoms may resemble those associated with the neoplastic process and changes in the course of systemic diseases (agranulocytosis). A correct diagnosis in these cases is necessary for adequate therapy. Chronic lymphocytic leukemia (CLL) is the most common type of leukemia among adults in Europe and North America. It is estimated that in Poland, CLL affects approximately 1,400 people per year. In this paper, a case of 62-years old patient with CLL with fungal infection of oral cavity and throat is presented.
Źródło:: Wiadomości Parazytologiczne; 2011, 57, 3; 155-158
0043-5163
Pojawia się w:: Wiadomości Parazytologiczne
Dostawca treści:: Biblioteka Nauki