- Tytuł:
- Synthesis and binding properties of deltorphin I analogues containing (R) and (S)-α-hydroxymethylnaphtylalanine.
- Autorzy:
-
Olma, Aleksandra
Gniadzik, Agnieszka
Lipkowski, Andrzej
Łachwa, Magdalena - Powiązania:
- https://bibliotekanauki.pl/articles/1044072.pdf
- Data publikacji:
- 2001
- Wydawca:
- Polskie Towarzystwo Biochemiczne
- Tematy:
-
deltorphin I analogues
amphiphilic amino acids
α,α-disubstituted amino acids
opioid peptides
opioid receptor binding
α-hydroksymethylamino acids - Opis:
- New analogues of deltorphin I (DT I), in which the phenylalanine residue in position 3 is substituted with amphiphilic α,α-disubstituted amino acid enantiomers, (R) and (S)-α-hydroxymethylnaphtylalanine, were synthesized and tested for μ and δ opioid receptor affinity and selectivity. Although both analogues have lower affinity to δ receptors than DT I, they both expressed specificity to δreceptors.
- Źródło:
-
Acta Biochimica Polonica; 2001, 48, 4; 1165-1168
0001-527X - Pojawia się w:
- Acta Biochimica Polonica
- Dostawca treści:
- Biblioteka Nauki
Artykuł