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Tytuł:
Constant Q-transform-based deep learning architecture for detection of obstructive sleep apnea
Autorzy:
Kandukuri, Usha Rani
Prakash, Allam Jaya
Patro, Kiran Kumar
Neelapu, Bala Chakravarthy
Tadeusiewicz, Ryszard
Pławiak, Paweł
Powiązania:
https://bibliotekanauki.pl/articles/24200694.pdf
Data publikacji:
2023
Wydawca:
Uniwersytet Zielonogórski. Oficyna Wydawnicza
Tematy:
sleep apnea
convolutional neural network
constant Q-transform
deep learning
single lead ECG signal
non apnea
obstructive sleep apnea
bezdech senny
sieć neuronowa konwolucyjna
uczenie głębokie
sygnał EKG
obturacyjny bezdech senny
Opis:
Obstructive sleep apnea (OSA) is a long-term sleep disorder that causes temporary disruption in breathing while sleeping. Polysomnography (PSG) is the technique for monitoring different signals during the patient’s sleep cycle, including electroencephalogram (EEG), electromyography (EMG), electrocardiogram (ECG), and oxygen saturation (SpO2). Due to the high cost and inconvenience of polysomnography, the usefulness of ECG signals in detecting OSA is explored in this work, which proposes a two-dimensional convolutional neural network (2D-CNN) model for detecting OSA using ECG signals. A publicly available apnea ECG database from PhysioNet is used for experimentation. Further, a constant Q-transform (CQT) is applied for segmentation, filtering, and conversion of ECG beats into images. The proposed CNN model demonstrates an average accuracy, sensitivity and specificity of 91.34%, 90.68% and 90.70%, respectively. The findings obtained using the proposed approach are comparable to those of many other existing methods for automatic detection of OSA.
Źródło:
International Journal of Applied Mathematics and Computer Science; 2023, 33, 3; 493--506
1641-876X
2083-8492
Pojawia się w:
International Journal of Applied Mathematics and Computer Science
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Nanomedicine - a boon for respiratory disease management
Autorzy:
Balasubramanian, D.
Lavanya, S.J.
Girigoswami, A.
Girigoswami, K.
Powiązania:
https://bibliotekanauki.pl/articles/24200620.pdf
Data publikacji:
2023
Wydawca:
Stowarzyszenie Komputerowej Nauki o Materiałach i Inżynierii Powierzchni w Gliwicach
Tematy:
nanomedicine
asthma
chronic obstructive pulmonary disease
cystic fibrosis
respiratory diseases
nanomedycyna
astma
przewlekła obturacyjna choroba płuc
mukowiscydoza
choroby układu oddechowego
Opis:
Purpose: Respiratory diseases affect the lungs and other parts of the respiratory system. The respiratory disease affects hundreds of millions of humans, and premature death is observed in nearly four million people yearly. The major cause of the increase in this disease is the increased level of air pollution and higher tobacco usage in public places. Design/methodology/approach: We have used the search engines PubMed and Google Scholar for the keywords Respiratory diseases, Nanomaterials, diagnosis, Nanomedicine, and Target drug delivery; recent and relevant articles are selected for reviewing this paper. Findings: Nanomedicine is a recent field of research that deals with monitoring, repairing, theragnosis, and development of human biological systems at the sub-atomic level, where we utilize engineered nanodevices and nanostructures. The conventional therapeutic strategies designed for respiratory diseases have limited solubility and bioavailability. Moreover, the robust effect of the drugs led to adverse side effects due to their high dose requirement. The local delivery of therapeutic Nanoparticles (NPs) or drug-loaded nano vehicles to the lung is a safe technique for managing various respiratory tract-related diseases like chronic obstructive pulmonary diseases, cystic fibrosis, lung cancer, tuberculosis, asthma, and infection. To overcome the difficulties of conventional treatment with antibiotics and anti-inflammatory drugs, nano-enabled drug delivery, nanoformulations of drugs as well as drug nanoencapsulation have been used recently. In this mini-review, we will discuss the importance and application of nanomedicine for diagnosis, treatment and clinical research involved in the different types of respiratory diseases. Practical implications: Nanomedicine provides an alternative delivery of drugs with the help of various nanocarriers, which enhances controlled drug delivery at the pulmonary region and can be used for treating and diagnosing respiratory diseases in vivo and in vitro studies. Further experiments followed by clinical examination are warranted to prove the potential application of nanomedicine in treating respiratory disease. Originality/value: This mini-review will help the readers and budding scientists apply new methods for developing highly efficient drugs with low side effects and improved targeted sites of action.
Źródło:
Archives of Materials Science and Engineering; 2023, 119, 2; 71--85
1897-2764
Pojawia się w:
Archives of Materials Science and Engineering
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Predictors of hospitalization in patients presenting to emergency department with an acute exacerbation of COPD – a single-center study in Turkey
Autorzy:
Sanalp Menekşe, Tuğba
Taha Sert, Ekrem
Powiązania:
https://bibliotekanauki.pl/articles/29519429.pdf
Data publikacji:
2023-09-30
Wydawca:
Uniwersytet Rzeszowski. Wydawnictwo Uniwersytetu Rzeszowskiego
Tematy:
chronic obstructive pulmonary disease
emergency department
hospitalization
Opis:
Introduction and aim. In this study, we evaluated parameters that might be associated with hospitalization in patients admitted to the emergency department (ED) with an acute exacerbation of chronic obstructive pulmonary disease (AECOPD). Material and methods. Patients with COPD who presented to ED due to AECOPD between January 1, 2020 and December 31, 2021 were included in the study. Patient data were obtained from the hospital database. Univariable and multivariable logistic regression methods were used to identify the relationship between hospitalization and clinical parameters. Results. The study included 237 patients divided into two groups: inpatients (n=124) and outpatients (n=113). We found significant differences between the two groups in terms of temperature, oxygen saturation, respiratory rate, C-reactive protein, white blood cell count, procalcitonin, albumin, arterial blood pH, pCO2, and non-invasive mechanical ventilation (NIMV) requirement. Multivariable logistic regression analysis showed that body temperature [odds ratio (OR):1.62;95% confidence interval (CI):1.21–4.91; p<0.001], oxygen saturation (OR:0.73, 95% CI:0.39-0.94, p<0.001), respiratory rate (OR:1.96; 95% CI: 1.07–6.14; p<0.001), albumin (OR:0.71; 95% CI:0.41–0.93; p=0.042), procalcitonin (OR:2.93; 95% CI:1.22–4.84; p<0.001), arterial blood pH (OR:0.78; 95% CI:0.29-0.91; p=0.038), pCO2 (OR:2.45; 95% CI:1.24–4.65; p<0.001), and NIMV requirement (OR:2.31; 95% CI:1.41–5.13; p<0.001) were the independent predictors of hospitalization. Conclusion. Our findings may help identify patients who will require hospitalization at an early stage.
Źródło:
European Journal of Clinical and Experimental Medicine; 2023, 3; 561-566
2544-2406
2544-1361
Pojawia się w:
European Journal of Clinical and Experimental Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Comorbidities and clinical outcomes of a lung cancer screening trial participants with chronic obstructive pulmonary disease in three-year follow-up
Autorzy:
Undrunas, Aleksandra
Bąk, Agata
Kasprzyk, Piotr
Dziedzic, Robert
Dziurda, Dominik
Rzyman, Witold
Gierlotka, Marek
Kuziemski, Krzysztof
Powiązania:
https://bibliotekanauki.pl/articles/25714585.pdf
Data publikacji:
2022-10-03
Wydawca:
Gdański Uniwersytet Medyczny
Tematy:
chronic obstructive pulmonary disease
diagnostic radiology
oncology
lung cancer
respiratory tract
screening
Opis:
Background To improve the effectiveness of lung cancer screening using low-dose computed tomography (LDCT), the presence of smoking-related comorbidities that may significantly affect mortality in this group should be taken into account. Material and methods A questionnaire survey and spirometry tests were conducted in a group of 730 respondents as part of a lung cancer screening study between 2016 and 2018. People diagnosed with COPD underwent a three-year follow-up to assess the incidence of medical events. Results Our study confirmed that cardiovascular diseases (CVDs) were the most common comorbidities in patients who were diagnosed with COPD and participated in LDCT lung cancer screening. Among the CVDs, the most common were arterial hypertension (45.8%) and coronary artery disease (12.5%). Tobacco-related diseases (e.g. CVD, lung cancer, and exacerbations of COPD) were the leading causes of emergency department visits and hospitalizations. The number of visits due to COPD in specialized clinics more than doubled in the observed period. Conclusions Properly planned screening tests allow not only for the detection of the disease for which they were designed but also for the assessment of comorbidities. In patients undergoing lung cancer screening, it is justified to extend the diagnostics to include spirometry.
Źródło:
European Journal of Translational and Clinical Medicine; 2022, 5, 2; 24-30
2657-3148
2657-3156
Pojawia się w:
European Journal of Translational and Clinical Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Floppy eyelid syndrome as an ocular condition associated with increased body mass index - classification, diagnostics and treatment
Autorzy:
Szabelska, Paulina
Ofman, Wacław
Białas, Dominika
Różycki, Radosław
Gołębiewska, Joanna
Powiązania:
https://bibliotekanauki.pl/articles/2232258.pdf
Data publikacji:
2022-12-31
Wydawca:
Medical Education
Tematy:
oflppy eyelid syndrome
FES
body mass index
obesity
eyelid sur gery
obstructive sleep apnea
OSAHS
Opis:
Floppy eyelid syndrome is a common ophthalmic condition characterized by a sagging eyelid, which causes its spontaneous wrinkling during sleep. It can be a result of local and systemic diseases. A characteristic group of patients who suffer from floppy eyelid syndrome are middle aged men with an increased body mass index. Obesity in this group of patients is recognized as the strongest risk factor for the occurrence of obstructive sleep apnea syndrome. The aim of the article is to review the diagnostic methods that are used in the case of floppy eyelid syndrome. The paper also discusses therapeutic methods including surgical techniques.
Źródło:
OphthaTherapy; 2022, 9, 4; 219-224
2353-7175
2543-9987
Pojawia się w:
OphthaTherapy
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Speech-language therapists’ awareness of the use of orofacial myofunctional therapy as a treatment of obstructive sleep apnoea in Czechia
Świadomość logopedów na temat stosowania terapii miofunkcjonalnej w sferze orofacjalnej jako metody leczenia obturacyjnego bezdechu sennego w Czechach
Autorzy:
Vitásková, Kateřina
Červinková, Karolína
Mironova Tabachová, Jana
Powiązania:
https://bibliotekanauki.pl/articles/24201485.pdf
Data publikacji:
2022-06-30
Wydawca:
Wydawnictwo Uniwersytetu Śląskiego
Tematy:
obturacyjny bezdech senny
zaburzenia miofunkcjonalne
terapia miofunkcjonalna
terapia logopedyczna
podejście interdyscyplinarne
obstructive sleep apnoea
myofunctional disorder
myofunctional therapy
speech-language therapy
interdisciplinary approach
Opis:
Obstructive sleep apnoea is an increasingly frequent lifestyle disease which affects both children and adults, affecting more than 10% of the adult population. The risk factors include unhealthy lifestyle, older age, structural and functional changes in the orofacial area as well as spinal cord injuries. Presently, there is no specific treatment of this disorder. One of the options for supportive treatment to alleviate the occurrence of apnoea during sleep is orofacial myofunctional therapy. The aim of the research presented in the article was to identify speech-language therapists’ awareness of the application of myofunctional therapy as a treatment of obstructive sleep apnoea and their awareness of the therapeutic methods in patients under supervision of a speech-language therapist. The aim of the paper is to emphasize the possibility of using myofunctional therapy among patients with obstructive sleep apnoea.
Obturacyjny bezdech senny jest coraz częściej występującą chorobą cywilizacyjną, diagnozowaną u dzieci i dorosłych, dotyczącą ponad 10% dorosłej populacji. Do czynników ryzyka należą: niezdrowy tryb życia, podeszły wiek, zmiany strukturalne i czynnościowe w sferze orofacjalnej, urazy rdzenia kręgowego. Obecnie nie ma specyficznej metody leczenia tego zaburzenia. Jedną z możliwości leczenia wspomagającego, łagodzącego występowanie bezdechu podczas snu, jest terapia miofunkcjonalna orofacjalna. Celem badań przedstawionych w artykule było określenie świadomości logopedów na temat zastosowania terapii miofunkcjonalnej jako metody leczenia obturacyjnego bezdechu sennego oraz metod prowadzenia terapii u pacjentów pod nadzorem logopedy. Celem pracy jest zwrócenie uwagi na możliwość stosowania terapii miofunkcjonalnej u pacjentów z obturacyjnym bezdechem sennym.
Źródło:
Logopedia Silesiana; 2022, 11, 1; 1-17
2300-5246
2391-4297
Pojawia się w:
Logopedia Silesiana
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Effects of propofol and dexmedetomidine in sleep videoendoscopy: a comparative study in Ukraine
Autorzy:
Denysenko, Roman
Dichtiaruk, Oleksandr
Naumenko, Oleksandr
Powiązania:
https://bibliotekanauki.pl/articles/1399239.pdf
Data publikacji:
2020
Wydawca:
Index Copernicus International
Tematy:
dexmedetomidine
obstructive sleep apnea syndrome
propofol
sleep videoendoscopy
Opis:
Introduction: Snoring and obstructive sleep apnea (OSA) are associate with a high socio-economic burden. According to statistics snoring is found in 44% of men and 28% of women aged 30 to 60 years. Treatment involves several main approaches including uvulopalatopharyngoplasty with or without tonsillectomy. Preparation for this procedure includes sleep videoendoscopy. Currently, we mainly use two effective agents, propofol and dexmedetomidine. That said, there is still no consensus on which one is safer and better. Material and methods: The study involved 50 people aged 18 to 62 with a history of snoring and OSA, previously ineligible or insensitive to CPAP therapy, thus preparing for surgical treatment of these disorders. All patients were randomized to two study groups: group 1 with propofol as a sedative and group 2 with dexmedetomidine. Each treatment was divided into three periods: (1) initial testing before the use of intravenous hypnotic agents, (2) sedation, and (3) regaining consciousness. In each period, we measured the following parameters: minute ventilation, respiratory rate, oxygen saturation, blood concentration of hypnotic agent, BIS index. Statistical analysis was performed on IBM SPSS Statistics v. 22. Results: The OAA/S scale showed that the recovery time after sedation was longer for dexmedetomidine than for propofol: 38 ± 10 min and 27 ± 3 min, respectively (p value = 0.305, which means no statistically significant difference between the groups). Based on monitoring of circulation and respiratory rate, heart rate tended to decrease with dexmedetomidine seda tion and increase with propofol infusion. Blood pressure tended to drop in both groups, more so with dexmedetomidine. In the post-sedation period, blood pressure stabilized faster in the propofol group than in the dexmedetomidine group, but it was not statistically significant. Conclusion: According to the study results, there was no statistically significant difference between the propofol or dexmedetomidine groups. However, the paper presents a small series of cases, therefore extensive clinical research is needed to clarify the problem further.
Źródło:
Polski Przegląd Otorynolaryngologiczny; 2020, 9, 3; 12-16
2084-5308
2300-7338
Pojawia się w:
Polski Przegląd Otorynolaryngologiczny
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Exhaled nitric oxide in smokers and former smokers with chronic obstructive pulmonary disease
Autorzy:
Galiniak, S.
Aebisher, D.
Rachel, M.
Powiązania:
https://bibliotekanauki.pl/articles/2087917.pdf
Data publikacji:
2020
Wydawca:
Uniwersytet Opolski. Instytut Nauk o Zdrowiu
Tematy:
nitric oxide
smoking
respiratory diseases
chronic obstructive pulmonary disease
Opis:
Background: Measurement of fractional exhaled nitric oxide (FeNO) is a useful technique for detection of eosinophilic airway inflammation and assessment of efficiency of corticosteroid treatment in patents with respiratory disease. Generally studies agree that measurement of FeNO is a useful non-invasive biomarker in patients with chronic obstructive pulmonary disease (COPD), however, there are reports that do not confirm such a relationship between FeNO and COPD. Aim of the study: The main objective of this study was to investigate FeNO levels in Polish patients with COPD compared to healthy controls. As a secondary objective, we assessed the influence of smoking on FeNO levels in healthy patients, and patients with COPD. Material and methods: FeNO concentration was measured using an electrochemical analyzer in healthy nonsmokers (n=21), healthy smokers (n=25), and former smokers with COPD (n=30) and smokers with COPD (n=38). General characteristics, hematological variables and serum biochemical parameters were also obtained and analyzed using the Kruskal-Wallis test. Results: FeNO measurement revealed significantly reduced NO levels in healthy smokers compared to healthy non-smokers, former smokers with COPD and smokers with COPD (median [range]: 14 [6–17] vs. 21 [15–29], 25 [15–53], and 19 [11–32] ppb, respectively, p<0.001). Moreover, we found increased FeNO levels in ex-smokers with COPD compared with smokers with COPD (p<0.05). No associations between FeNO and other analyzed parameters were found. Conclusions: Levels of FeNO, measured by with an electrochemical analyzer, were elevated among patients with COPD compared to healthy non-smoking controls. Moreover, our study confirms that smoking results in a reduction in FeNO concentration in both healthy patients and patients with COPD.
Źródło:
Medical Science Pulse; 2020, 14, 2; 36-43
2544-1558
2544-1620
Pojawia się w:
Medical Science Pulse
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Gastro-esophageal reflux and obstructive sleep apnea – is there a link?
Autorzy:
Pardak, Piotr
Pękala, Anna
Jarmakiewicz, Sara
Filip, Rafał
Powiązania:
https://bibliotekanauki.pl/articles/2037608.pdf
Data publikacji:
2020-06-30
Wydawca:
Uniwersytet Rzeszowski. Wydawnictwo Uniwersytetu Rzeszowskiego
Tematy:
gastro-esophageal reflux
ghrelin, obesity
obstructive sleep apnea
Opis:
Introduction. The epidemic of obesity has led to an increase in the occurrence of obstructive sleep apnea and gastro-esophageal reflux disease. The mechanism of development of gastro-esophageal reflux disease is multifactorial, and studies conducted in the last decade have shed new light on the causes of its development in patients with sleep apnea and obesity. Aim. The aim of the study was to discuss the mechanism of development of gastro-esophageal reflux disease is multifactorial, and studies conducted in the last decade have shed new light on the causes of its development in patients with sleep apnea and obesity and the dysfunction of the lower esophageal sphincter. Material and methods. An analysis of literature regarding gastro-esophageal reflux and obstructive sleep apnea. Results. In obstructive sleep apnea and obesity, high levels of cytokines and insulin resistance are observed, resulting in disorders in the levels of ghrelin – a hormone responsible for normal gastrointestinal motility. Conclusion. The effect of deviations in the ghrelin profile on the development of gastro-esophageal reflux disease remains a matter for further research
Źródło:
European Journal of Clinical and Experimental Medicine; 2020, 2; 110-115
2544-2406
2544-1361
Pojawia się w:
European Journal of Clinical and Experimental Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Histological evaluation of soft palate tissues in patients with sleep-disordered breathing
Autorzy:
Panek, Justyna
Reszeć, Joanna
Rogowski, Marek
Olszewska, Ewa
Powiązania:
https://bibliotekanauki.pl/articles/1397297.pdf
Data publikacji:
2020
Wydawca:
Index Copernicus International
Tematy:
CD20
CD3
CD34
S-100 protein
snoring
soft palate
obstructive sleep apnea syndrome
Opis:
Introduction: Sleep is a physiological state essential for the proper functioning of the body. One of the reasons for its disturbance is obstructive sleep apnea syndrome (OSAS). Aim: The aim of this research is the histological evaluation of the soft palate in patients who suffered from various types of OSAS. Material and method: The study group consisted of patients with sleep-disordered breathing (SDB) in the form of primary snoring or OSAS. Patients with chronic tonsillitis, without a history of SDB, were included in the comparative group. Fragments of the mucous of the uvula (study group) and the palatoglossal pillar (comparative group) were obtained during surgery for histological evaluation. Using histological, histochemical and immunohistochemical methods, we assessed the inflammation and its severity (CD3, CD20, CD68), the structure of nerve fibers (S-100) and the size of blood vessels (CD34) in the examined tissue. Results: Patients with OSAS developed a local inflammatory process in the palatal tissues (stronger expression of CD3, CD20, CD68 in patients with OSAS). The severity of the immunohistochemical reaction with CD3 correlated with the stage of OSAS. A higher degree of fibrosis and a higher expression of CD34 and S-100 receptors were observed in patients with OSAS compared to snoring patients and patients from the comparative group. Conclusion: Most likely, snoring due to chronic tissue vibration leads to damage to the nerve fibers in the soft palate, which can intensify episodes of hypopneas during and increase the chance for sleep apneas.
Źródło:
Polish Journal of Otolaryngology; 2020, 74, 1; 6-12
0030-6657
2300-8423
Pojawia się w:
Polish Journal of Otolaryngology
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Postępowanie lekarskie w obturacyjnym bezdechu sennym u osób kierujących pojazdami − zalecenia Polskiego Towarzystwa Medycyny Pracy, Polskiego Towarzystwa Chorób Płuc, Instytutu Medycyny Pracy w Łodzi i Polskiego Towarzystwa Badań nad Snem
The management of obstructive sleep apnea syndrome in drivers − recommendations of the Polish Society Of Occupational Medicine, The Polish Respiratory Society, The Nofer Institute of Occupational Medicine in Lodz and The Polish Sleep Research Society
Autorzy:
Siedlecka, Jadwiga
Rybacki, Marcin
Pływaczewski, Robert
Czajkowska-Malinowska, Małgorzata
Radliński, Jakub
Kania, Aleksander
Śliwiński, Paweł
Powiązania:
https://bibliotekanauki.pl/articles/2085456.pdf
Data publikacji:
2020-03-30
Wydawca:
Instytut Medycyny Pracy im. prof. dra Jerzego Nofera w Łodzi
Tematy:
obturacyjny bezdech senny
kierowcy
algorytm postępowania
Kwestionariusz EuroSAS
Skala senności Epworth
zalecenia
obstructive sleep apnea syndrome
drivers
algorithm of management
EuroSAS Questionnaire
Epworth Sleepiness Scale
recommendations
Opis:
Na podstawie wyników wielu badań i analiz prowadzonych w różnych krajach potwierdzono, że obturacyjny bezdech senny (OBS) negatywnie wpływa na zdolności psychofizyczne kierowców. Dlatego w Dyrektywie Unii Europejskiej z dnia 1 lipca 2014 r. OBS został uznany za jeden z najważniejszych czynników ryzyka wypadków samochodowych. Realizacja postanowień tej dyrektywy w państwach członkowskich ma przyczynić się do jego ograniczenia. Wynikiem jej implementacji w Polsce jest rozporządzenie Ministra Zdrowia z dnia 23 grudnia 2015 r. zmieniające rozporządzenie w sprawie badań lekarskich osób ubiegających się o uprawnienia do kierowania pojazdami i kierowców. Mimo że w załączniku nr 2 tego rozporządzenia podano szczegółowe warunki badania lekarskiego w przypadku podejrzenia OBS, nie uregulowano ani nie wyjaśniono kwestii narzędzi i sposobu pozwalających na powzięcie w przypadku badanego pacjenta podejrzenia umiarkowanej lub ciężkiej postaci choroby. Dlatego konieczne było opracowanie dla lekarzy uprawnionych do badań lekarskich kierowców i osób ubiegających się o prawo jazdy standardów postępowania w przypadku podejrzenia występowania OBS. W artykule przedstawiono usprawniający proces orzeczniczy algorytm postępowania, który został opracowany przez Polskie Towarzystwo Medycyny Pracy, Polskie Towarzystwo Chorób Płuc, Instytut Medycyny Pracy w Łodzi i Polskie Towarzystwo Badań nad Snem. Med. Pr. 2020;71(2):233–243
The findings of numerous studies and analyzes conducted in many countries have proven that obstructive sleep apnea (OSA) negatively affects the psychophysical abilities drivers. Therefore, in Commission Directive 2014/85/EU of July, 1 2014, OSA was recognized as one of the most important risk factors for car accidents. The implementation of said Directive by Member States is to contribute to reducing the risk of such accidents. The implementation of the Directive in Poland has resulted in enacting the Ordinance of the Minister of Health of December 23, 2015 amending the ordinance on medical examinations of applicants for a driving license and drivers. Although Annex 2 to that regulation sets out the detailed conditions for a medical examination for OSA, it does not regulate or clarify the issue of tools and methods for suspecting OSA in a moderate or hard form. Therefore, it was necessary to develop standards of management for doctors authorized to perform medical examinations of drivers and applicants for a driving license in the case of suspected OSA. The paper presents an algorithm of proceedings that streamlines the case-law process in the above-mentioned cases, which was developed by the Polish Society of Occupational Medicine in cooperation with the Polish Respiratory Society, the Nofer Institute of Occupational Medicine in Łódź and the Polish Sleep Research Society. Med Pr. 2020;71(2):233–43
Źródło:
Medycyna Pracy; 2020, 71, 2; 233-243
0465-5893
2353-1339
Pojawia się w:
Medycyna Pracy
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Sleep apnea and dry eye: how sleep apnea affects the eye surface
Autorzy:
Bommert, Catherina M.
Grupcheva, Christina N.
Radeva, Mladena N.
Grupchev, Dimitar I.
Boyadzieva, Maria R.
Powiązania:
https://bibliotekanauki.pl/articles/1927968.pdf
Data publikacji:
2020-06-30
Wydawca:
Medical Education
Tematy:
continuous positive airway pressure
dry eye syndrome
obstructive sleep apnea
Opis:
Purpose: The purpose of this study was to determine the presence of dry eye disease and possible treatment options in patients with obstructive sleep apnea and continuous positive airway pressure. Materials and methods: A total of 72 patients (midlife age) with obstructive sleep apnea and continuous positive airway pressure therapy underwent a comprehensive eye examination. Fluorescein staining of the anterior ocular surface and tear break-up test were performed. All of the patients who were diagnosed with dry eye disease received personalized therapy. One month later, re-examination was performed using the same methodology and clinical settings. Results: On the first examination, 48 of 72 patients (66.67%) were diagnosed with dry eye disease. Floppy eyelid syndrome was reported in 26 patients (54.17%) with dry eye disease. The treatment of 40 patients included artificial tear supplements during the day in combination with high-viscosity topical gels before bedtime. In more severe cases (10.42% of all participants), the application of bandage contact lenses for 3 months was necessary. Because of excessive lid laxity, surgical reconstruction of the eyelids was performed in three patients (6.25%). Conclusions: A multidisciplinary approach is essential for obstructive sleep apnea. Practitioners from different specialties must be well acquainted with risk factors, signs, and symptoms. The early detection of dry eye disease in patients with obstructive sleep apnea and appropriate treatments are important for improving the quality of life in this patient group.
Źródło:
OphthaTherapy; 2020, 7, 2; 103-107
2353-7175
2543-9987
Pojawia się w:
OphthaTherapy
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
The 30-day mortality predictor role of c-reactive protein/albumin ratio in critically ill COPD patients
Autorzy:
Cırık, Mustafa Özgür
Baldemir, Ramazan
Doğanay, Güler Eraslan
Ünver, Meriç
Avcı, Sema
Powiązania:
https://bibliotekanauki.pl/articles/29432111.pdf
Data publikacji:
2020-12
Wydawca:
Towarzystwo Pomocy Doraźnej
Tematy:
C-reactive protein
albumin
chronic obstructive pulmonary disease
mortality
Opis:
INTRODUCTION: Chronic Obstructive Pulmonary Disease (COPD) is a progressive disease that develops due to inflammation in the airways. The aim of this study is to demonstrate the effectiveness of c-reactive protein/albumin ratio (CAR) as a 30-day mortality indicator in COPD patients admitted to ICU. MATERIAL AND METHODS: A total of 235 COPD patients with available data between January 2018 and December 2018 were included in this retrospective cohort study. Demographics, APACHE II, Charlson comorbidity index (CCI), SOFA score, CAR and outcomes were evaluated. RESULTS: 87 (37%) of the cases were female and 148 (63%) were male. Their ages ranged from 26 to 95 years, with an average of 70.9± 11.4. The non-survivors had significantly higher APACHE II, CCI, SOFA score, procalcitonin, creatinine, mechanical ventilation (MV) time, WBC, CRP and CAR compared to the survivors (p˂0.05). Albumin and prealbumin were significantly lower (p˂0.05) in non-survivors. In the univariate model; age, sepsis, inotropic support, APACHE II score, CCI, SOFA, procalcitonin, creatinine, MV time, WBC, CRP, albumin, prealbumin and CAR were observed to be significantly effective (p˂0.05) in predicting 30-day mortality. In the multivariate reduced model; inotropic support, SOFA, WBC and prealbumin value exhibited significant independent (p<0.05) effectiveness in predicting 30-day mortality. Albumin, CRP, CAR, APACHE II, SOFA and CCI value were observed to be significant in predicting mortality (p=0.000). CONCLUSIONS: In the study, the predictive power of APACHE II score, CCI, SOFA score, albumin and prealbumin values alone was found to be significantly higher than that of the CAR.
Źródło:
Critical Care Innovations; 2020, 3, 4; 1-12
2545-2533
Pojawia się w:
Critical Care Innovations
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
The effect of concomitant gastroesophageal reflux disease on clinical course and lung function in patients with chronic obstructive pulmonary disease
Wpływ współistniejącej choroby refluksowej przełyku na przebieg kliniczny i czynność płuc u pacjentów z przewlekłą obstrukcyjną chorobą płuc
Autorzy:
Titkova, A.
Powiązania:
https://bibliotekanauki.pl/articles/2048903.pdf
Data publikacji:
2020
Wydawca:
Akademia Bialska Nauk Stosowanych im. Jana Pawła II w Białej Podlaskiej
Tematy:
gastroesophageal reflux disease
chronic obstructive pulmonary disease
comorbidity
choroba refluksowa przełyku
przewlekła obturacyjna choroba płuc
choroby współistniejące
Opis:
Background. Chronic obstructive pulmonary disease (COPD) is one of the leading causes of morbidity and mortality in modern society and can lead to the development of comorbidities. Among the last, gastroesophageal reflux disease (GERD) is frequently present, but often gets a close attention from doctors in the treatment of pulmonary patients. The aim of the current study was to determine the characteristics of clinical and lung disorders in the pathogenesis of COPD with concomitant GERD. Material and methods. We examined 113 COPD patients with isolated COPD or with COPD and concomitant GERD. All the patients underwent spirography, endoscopy, radiological and pH-metric procedures. Results. Many patients (95%) with concomitant pathology complained of heartburn, dysphagia, especially after meals, burning tongue, hoarseness and a lump in the throat. Among COPD patients without concomitant GERD, both clinical pulmonary manifestations met with almost the same frequency but were less pronounced (p>0.05). During the lung examination, we determined the level of FEV1, VC, FVC, FEF25-75 and FEV1/FVC, which differed significantly in COPD patients (p<0.05) compared to predicted normal values in human of the same sex, age, height and body weight. In the COPD with concomitant GERD cohort, a sharp decrease in spirography indices was found compared to patients with isolated COPD (p<0.001). Conclusions. COPD patients with concomitant GERD had significantly greater extraesophageal manifestations and lung disorders compared with COPD patients without comorbidity.
Wprowadzenie. Przewlekła obturacyjna choroba płuc (POChP) jest jedną z głównych przyczyn umieralności i zachorowań we współczesnym społeczeństwie, co w konsekwencji prowadzi do rozwoju chorób współistniejących. Choroba refluksowa przełyku (GERD) występuje często, ale zazwyczaj jest dokładnie badana u pacjentów z chorobami płuc. Celem badania jest określenie zaburzeń klinicznych i chorób płuc w patogenezie POChP z towarzyszącym GERD. Materiał i metody. Przebadanych zostało 113 pacjentów z POChP z izolowaną POChP oraz z POChP ze współistniejącym GERD. Wszystkich poddano zabiegom, takim jak: spirografia, endoskopia, a także działaniom radiologicznym i pH-metrycznym. Wyniki. Większość pacjentów ( 95%) ze współistniejącą patologią skarżyło się na zgagę, dysfagię, zwłaszcza po spożyciu posiłków, pieczenie języka, chrypkę oraz występowanie guzka w gardle. W tym czasie wśród pacjentów z POChP bez współistniejącej GERD oba objawy kliniczne w płucach spotkały się z prawie taką samą częstością, ale były mniej wyraźne (p>0,05). Podczas badania płuc ustalono poziomy FEV1, VC, FVC, FEF25-75, FEV1/FVC, które znacznie różniły się u pacjentów z POChP (p<0,05) w porównaniu do normalnych wartości u osób tej samej płci, wieku, wzrostu i masy ciała. W grupie pacjentów z POChP z towarzyszącym GERD stwierdzono gwałtowny spadek wskaźników spirograficznych w porównaniu z pacjentami z izolowaną POChP (p<0,001). Wnioski. Pacjenci z POChP ze współistniejącym GERD mieli znacznie większe objawy pozaprzełykowe i choroby płuc w porównaniu z pacjentami z POChP, ale bez chorób współistniejących.
Źródło:
Health Problems of Civilization; 2020, 14, 1; 29-33
2353-6942
2354-0265
Pojawia się w:
Health Problems of Civilization
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Methodologies of inspiratory muscle training techniques in obstructive lung diseases
Metodologie treningu mięśni wdechowych w chorobach obturacyjnych układu oddechowego
Autorzy:
Kaszuba, Marek
Śliwka, Agnieszka
Piliński, Rafał
Nowobilski, Roman
Wloch, Tomasz
Powiązania:
https://bibliotekanauki.pl/articles/1790967.pdf
Data publikacji:
2019-03-29
Wydawca:
Akademia Wychowania Fizycznego im. Bronisława Czecha w Krakowie
Tematy:
inspiratory muscle training
respiratory muscle training
pulmonary rehabilitation
pulmonary disease
chronic obstructive
asthma
trening mięśni wdechowych
trening mięśni oddechowych
rehabilitacja pulmonologiczna
przewlekła obturacyjna choroba
płuc
astma
Opis:
Background: Inspiratory muscle training (IMT) is a non-pharmacological, non-invasive therapeutic method that can improve the quality of life in patients with obstructive lung diseases. The effectiveness of IMT may depends on the type of the device used in the training and the parameters of the training programme. Objectives: The aim of the review was to present different techniques and protocols of IMT used in patients with obstructive lung diseases. Methods: The MEDLINE and EMBASE were searched to identify the potentially eligible publications from the previous 5 years. The various protocols of IMT used in different studies were analysed and described in detail. Results: A database search identified 333 records, of which 22 were included into the final analysis. All of the finally analysed studies were conducted in patients with chronic obstructive pulmonary disease (COPD). The protocols of IMT used in the studies differed in the type of the device used, the duration of the training programme, the number and the duration of training sessions, the initial load, and the rate at which the load was changed during the training. Conclusions: IMT is used mainly in studies on patients with COPD and not with asthma. There is no one approved training programme for IMT. The most predominant type of IMT is a training with threshold loading. The most frequently used devices for IMT are POWERbreath and Threshold IMT. The protocols of IMT used in the studies are very diverse.
WSTĘP: Trening mięśni oddechowych (IMT) należy do niefarmakologicznych, nieinwazyjnych metod terapeutycznych, które mogą prowadzić do poprawy jakości życia pacjentów z chorobami układu oddechowego. Skuteczność IMT może zależeć od rodzaju urządzenia użytego do treningu oraz parametrów programu treningowego. CELE: Celem przeglądu było przedstawienie różnych technik i protokołów IMT stosowanych u pacjentów z obturacyjnymi chorobami płuc. METODY: W celu zidentyfikowania publikacji z ostatnich 5 lat potencjalnie kwalifikujących się do analizy przeszukano elektroniczne bazy MEDLINE i EMBASE. Szczegółowo przeanalizowano i opisano protokoły IMT stosowane w różnych pracach badawczych. WYNIKI: W efekcie wyszukiwania w bazie danych zidentyfikowano 333 rekordy, z których 23 zostały włączone do ostatecznej analizy. Wszystkie finalnie przeanalizowane badania zrealizowano u pacjentów z przewlekłą obturacyjną chorobą płuc (POChP). Protokoły IMT stosowane w badaniach różniły się rodzajem stosowanego urządzenia, czasem trwania programu treningowego, liczbą i czasem trwania sesji treningowych, początkowym obciążeniem oraz szybkością zmiany obciążenia podczas treningu. WNIOSKI: IMT jest ostatnio stosowany głównie w badaniach nad pacjentami z POChP, a nie z astmą. Nie istnieje jeden zatwierdzony program treningowy dla IMT. Najczęściej stosowanym rodzajem IMT jest trening z obciążeniem progowym. Najbardziej rozpowszechnionymi urządzeniami do IMT są POWERbreath i Threshold IMT. Protokoły IMT wykorzystywane w badaniach naukowych są bardzo zróżnicowane.
Źródło:
Medical Rehabilitation; 2018, 22(4); 49-57
1427-9622
1896-3250
Pojawia się w:
Medical Rehabilitation
Dostawca treści:
Biblioteka Nauki
Artykuł
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