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    Wyświetlanie 1-3 z 3
    Tytuł:
    SNP panel for evaluation of genetic variability and relationship in roe deer (Capreolus capreolus)
    Autorzy:
    Oleński, K.
    Zalewski, D.
    Kamiński, S.
    Powiązania:
    https://bibliotekanauki.pl/articles/16647455.pdf
    Data publikacji:
    2023
    Wydawca:
    Polska Akademia Nauk. Czasopisma i Monografie PAN
    Tematy:
    Capreolus capreolus
    genetic diversity
    roe deer
    Single Nucleotide Polymorphism marker
    Opis:
    Blood samples from forty-six roe deer (Capreolus capreolus) acquired during officially approved hunting in six hunting divisions throughout Poland were used to isolate the genomic DNA. All individuals were genotyped by MD_Bovine BeadChip (Illumina) for 46.750 Single Nucleotide Polymorphism (SNP) markers. SNPs of inappropriate clusters, with a marker call rate lower than 90% and with a minor allele frequency (MAF) lower than 0.01, located on sex chromosomes and mitochondrial DNA, were removed. Altogether, 21.033 SNP markers were included for further analysis. Observed and expected heterozygosity amounted to 0.098 and 0.119, respectively. Among 21.033 markers, a panel of 148 SNPs were selected for relationship analysis. They were unlinked and had a MAF higher than 0.2. This set of SNPs showed a probability of parentage exclusion of 1.29x10 -6 and 2.37x10 -19 for one, and two known parents, respectively. The probability of identity was estimated at 1.8x10 -40. The probabilities obtained in this study are sufficient for the monitoring and effective management of the genetic diversity of roe deer in Poland and is a cost-effective complementary tool for forensic applications.
    Źródło:
    Polish Journal of Veterinary Sciences; 2023, 26, 1; 29-37
    1505-1773
    Pojawia się w:
    Polish Journal of Veterinary Sciences
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Sampling Properties of Estimators of Nucleotide Diversity at Discovered snp Sites
    Autorzy:
    Renwick, A.
    Bonnen, P. E.
    Trikka, D.
    Nelson, D. L.
    Chakraborty, R.
    Kimmel, M.
    Powiązania:
    https://bibliotekanauki.pl/articles/908150.pdf
    Data publikacji:
    2003
    Wydawca:
    Uniwersytet Zielonogórski. Oficyna Wydawnicza
    Tematy:
    genetyka
    statystyka
    single nucleotide polymorphisms
    ascertainment bias
    nucleotide diversity
    molecular evolution
    Opis:
    SNP sites are generally discovered by sequencing regions of the human genome in a limited number of individuals. This may leave SNP sites present in the region, but containing rare mutant nucleotides, undetected. Consequently, estimates of nucleotide diversity obtained from assays of detected SNP sites are biased. In this research we present a statistical model of the SNP discovery process, which is used to evaluate the extent of this bias. This model involves the symmetric Beta distribution of variant frequencies at SNP sites, with an additional probability that there is no SNP at any given site. Under this model of allele frequency distributions at SNP sites, we show that nucleotide diversity is always underestimated. However, the extent of bias does not seem to exceed 10-15% for the analyzed data. We find that our model of allele frequency distributions at SNP sites is consistent with SNP statistics derived based on new SNP data at ATM, BLM, RQL and WRN gene regions. The application of the theory to these new SNP data as well as to the literature data at the LPL gene region indicates that in spite of ascertainment biases, the observed differences of nucleotide diversity across these gene regions are real. This provides interesting evidence concerning the heterogeneity of the rates of nucleotide substitution across the genome.
    Źródło:
    International Journal of Applied Mathematics and Computer Science; 2003, 13, 3; 385-394
    1641-876X
    2083-8492
    Pojawia się w:
    International Journal of Applied Mathematics and Computer Science
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Genetic diversity in Vernonia amygdalina Delile accessions revealed by random amplified polymorphic DNAs (RAPDs)
    Autorzy:
    Aikpokpodion, P.
    Abebe, J.
    Igwe, D.
    Powiązania:
    https://bibliotekanauki.pl/articles/79809.pdf
    Data publikacji:
    2018
    Wydawca:
    Polska Akademia Nauk. Czytelnia Czasopism PAN
    Tematy:
    genetic diversity
    Vernonia amygdalina
    random amplified polymorphic DNA
    polymorphism
    molecular characteristics
    single-nucleotide polymorphism
    geographic differentiation
    Źródło:
    BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology; 2018, 99, 2
    0860-7796
    Pojawia się w:
    BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
      Wyświetlanie 1-3 z 3

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