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Tytuł:
Increased neurogenesis after ACEA and levetiracetam treatment in mouse pilocarpine model of epilepsy
Autorzy:
Zagaja, Mirosław
Szewczyk, Aleksandra
Haratym-Maj, Agnieszka
Rola, Radosław
Maj, Maciej
Łuszczki, Jarogniew J.
Anders-Mach, Marta
Powiązania:
https://bibliotekanauki.pl/articles/972512.pdf
Data publikacji:
2017
Wydawca:
Instytut Medycyny Wsi
Tematy:
neurogenesis
neurons
astrocytes
pilocarpine
ACEA
Levetiracetam
Opis:
Introduction and objectives. The aim of the study was to asses the impact of long-term therapy with the second generation antiepileptic drug levetiracetam (LEV) with arachidonyl-2’-chloroethylamide (ACEA), a highly selective cannabinoid CB1 receptor agoniston the process of neurogenesis in a mouse pilocarpine model of epilepsy (PILO). Additionally, a relationship was established between the treatment with ACEA in combination with LEV, and hippocampal neurogenesis in mouse PILO brain. Materials and method. All experiments were performed on adolescent male CB57/BL mice injected i.p. with LEV (10 mg/kg), ACEA (10 mg/kg) and PMSF (30 mg/kg) (phenylmethylsulfonyl fluoride — a substance protecting ACEA against degradation by the fatty-acid amidohydrolase), pilocarpine (PILO, a single dose 290 mg/kg) and methylscopolamine (30 min before PILO to stop the peripheral cholinergic effects of the pilocarpine, 1 mg/kg). The process of neurogenesis was evaluated after10 days treatment with LEV and ACEA. Results. Obtained results indicated that the combinations of ACEA+PMSF+LEV and ACEA +PMSF increased the total number of total newborn cells compared to the control. Moreover, ACEA+PMSF administered alone and in combination with LEV had a significant impact on neurogenesis increasing the total number of newborn neurons compared to the control group. Neither LEV nor PMSF had a significant impact on the number of proliferating cells and newborn neurons when compared to the control PILO group. In turn, LEV administered alone decreased significantly the number of astrocytes. However, ACEA+PMSF has demonstrated significant increase of astrocytes compare to control mice. Conclusions. These data provide substantial evidence that the combination of LEV+ACEA significantly increases the level of newborn neurons in the PILO dentate subgranular zone.
Źródło:
Journal of Pre-Clinical and Clinical Research; 2017, 11, 2; 136-141
1898-2395
Pojawia się w:
Journal of Pre-Clinical and Clinical Research
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
„Ludzki mózg jest potężną imitującą maszyną”. Teoria mimetyczna a badania nad naturą imitacji w naukach kognitywnych
“Human Brain is a Powerful Imitating Machine” Mimetic Theory and Research on the Nature of Imitation in Cognitive Sciences
Autorzy:
Strączek, Bogumił
Powiązania:
https://bibliotekanauki.pl/articles/495027.pdf
Data publikacji:
2016-09-30
Wydawca:
Towarzystwo Naukowe Franciszka Salezego
Tematy:
mimesis;
teoria mimetyczna;
psychologia rozwojowa;
nauki kognitywne;
neurony lustrzane;
mimetic theory;
developmental psychology;
cognitive science;
mirror neurons;
Opis:
This article attempts to trace the relationship between René Girard’s mimetic theory and re- search on the nature of imitation in cognitive sciences. It is divided into four parts. The first one defines the basic concept of the French thinker’s theory, i.e. that of mimetic desire, in the context of such notions as biological, cultural and psychological mimicry. The second refers to the research conducted in the area of developmental psychology on mimetic behaviours of infants. The third part shows how imitative behaviours are reflected in the activity of neurons. The fourth chapter describes the most recent findings, which directly relate to the theory of René Girard’s mimetic desire.
Źródło:
Seminare. Poszukiwania naukowe; 2016, 37, 3; 47-60
1232-8766
Pojawia się w:
Seminare. Poszukiwania naukowe
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Dispersal and immunohistochemical characteristics of neurons in the stem of the porcine vagus nerve
Autorzy:
Sienkiewicz, W.
Klimczuk, M.
Majewska, M.
Kaleczyc, J.
Powiązania:
https://bibliotekanauki.pl/articles/16647386.pdf
Data publikacji:
2022
Wydawca:
Polska Akademia Nauk. Czasopisma i Monografie PAN
Tematy:
vagus nerve
intravagal neurons
neurotransmitter markers
immunohistochemistry
pig
Opis:
The present study investigated the distribution and chemical properties of nerve cell bodies within the trunk of the vagus nerve in juvenile female pigs (n=4) using double-labelling immunofluorescence. The neurons appeared mostly as single cells or formed streaks of cells or small ganglia. Many of the perikarya were cholinergic (VAChT-positive; VAChT+) or adrenergic (DβH+) in nature and no SP+ or CGRP+ neurons were encountered. There were no distinct left-right differences regarding the number and chemical coding of the neuronal somata, however, these characteristics significantly varied between particular nerve segments investigated. The vagosympathetic trunks, and thoracic and abdominal segments of the vagus nerve contained on average (the numerical values represent the means for both the left and right corresponding nerve segments) 142, 236, and 111 PGP 9.5-positive neurons, respectively. Proportions of cholinergic and adrenergic neurons were as follows: 0% and 100%, 54.2% and 33.2%, and 52.8% and 35.4%, respectively. Relatively many neurons in the thoracic and abdominal segments stained also for NOS (39.2% and 39.9%, respectively). It remains to be determined whether the porcine intravagal neurons represent a developmental relic, or whether they have any specific functional significance.
Źródło:
Polish Journal of Veterinary Sciences; 2022, 25, 4; 617-619
1505-1773
Pojawia się w:
Polish Journal of Veterinary Sciences
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Immunohistochemical characterization of nerve elements in porcine intrinsic laryngeal ganglia
Autorzy:
Sienkiewicz, W.
Klimczuk, M.
Gulbinowicz-Gowkielewicz, M.
Lepiarczyk, E.
Kaleczyc, J.
Powiązania:
https://bibliotekanauki.pl/articles/16539221.pdf
Data publikacji:
2022
Wydawca:
Polska Akademia Nauk. Czasopisma i Monografie PAN
Tematy:
larynx
intrinsic neurons
pig
immunohistochemistry
biologically active substances
Opis:
The present study investigated the chemical coding of neurons and nerve fibres in local laryngeal ganglia in pigs (n=5) using double-labelling immunohistochemistry. Virtually all the neurons were cholinergic in nature (ChAT- or VAChT-positive). Only very solitary, small nerve cells (presumably representing interneurons) stained intensely for adrenergic marker, DβH. Many neurons also contained immunoreactivity for NOS (91%), VIP (62.7%), NPY (24.7%), galanin (10%), SP (1.3%) and CGRP (5.3%). No neurons expressing somatostatin or Leu-enkephalin were observed. Nearly all the neuronal somata were densely supplied with varicose cholinergic nerve terminals, which presumably represented preganglionic axons, and some of them were also closely apposed with CGRP- and/or SP-positive varicose nerve endings, which were putative collaterals of extrinsic primary sensory fibres. In conclusion, this study has revealed that intrinsic neurons in the porcine larynx, like in many other mammalian species studied, should be classified as parasympathetic cholinergic neurons expressing biologically active substances, predominantly NOS and VIP. Furthermore, they are likely to receive inputs from not only preganglionic neurons but also primary sensory nerve cells. Finally, it appears that the information on the occurrence of the local laryngeal ganglia should be regularly included in textbooks dealing with the cranial portion of the parasympathetic nervous system in mammals.
Źródło:
Polish Journal of Veterinary Sciences; 2022, 25, 2; 325-334
1505-1773
Pojawia się w:
Polish Journal of Veterinary Sciences
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Enteric neuronal development in canine small intestine – an immunohistochemical study
Autorzy:
Serzysko, T.
Skwarek, A.
Chudziak, E.
Malina, M.
Kaleczyc, J.
Sienkiewicz, W.
Powiązania:
https://bibliotekanauki.pl/articles/2087175.pdf
Data publikacji:
2021
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
dog
fetus
small intestine
enteric nervous system
development
neurons
immunohistochemistry
Źródło:
Polish Journal of Veterinary Sciences; 2021, 24, 2; 293-301
1505-1773
Pojawia się w:
Polish Journal of Veterinary Sciences
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Perception-based reasoning: evaluation systems
Autorzy:
Rutkowska, D.
Powiązania:
https://bibliotekanauki.pl/articles/1931577.pdf
Data publikacji:
2003
Wydawca:
Politechnika Gdańska
Tematy:
fuzzy sets
perception-based systems
fuzzy neurons
neural networks
artificial intelligence
Opis:
A perception-based interpretation of evaluation systems is proposed in this paper. Thus, a perception-based approach to create intelligent systems is considered. The evaluation systems can be employed eg. in order to assess student exams, as well as to other applications. Evaluation marks used in these systems are given as perceptions expressed by words. The words play the role of labels of perceptions, and are represented by fuzzy sets. This means that the idea of perception-based systems, introduced by Zadeh, is applied. Various algorithms of overall assessment are suggested in this paper. Overall evaluation is produced as an aggregation of component evaluation marks. Systems of this kind can be obtained using fuzzy neurons, so fuzzy neural networks are also mentioned as a method of perception-based reasoning. The usefulness in artificial intelligence of both fuzzy sets and neural networks, and especially a combination of these, is shown.
Źródło:
TASK Quarterly. Scientific Bulletin of Academic Computer Centre in Gdansk; 2003, 7, 1; 131-145
1428-6394
Pojawia się w:
TASK Quarterly. Scientific Bulletin of Academic Computer Centre in Gdansk
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Czy potrzebny jest nowy model neuropoezy?
Do we need a new model of neuropoiesis?
Autorzy:
Rieske, Piotr
Powiązania:
https://bibliotekanauki.pl/articles/1061273.pdf
Data publikacji:
2006
Wydawca:
Medical Communications
Tematy:
astrocytes
astrocyty
neural stem cells
neurons
neuropoiesis
suppression of discordant phenotypes
neurony
neuropoeza
supresja niespójnych fenotypów
neuralne komórki macierzyste
Opis:
Models of neuropoiesis make it possible to determine at what stage of differentiation are neuronal cells. These models reflect our current knowledge about neuropoiesis, but they have also practical significance. In vitro determination whether neuronal stem cells differentiate to neuronal, astrocytic or oligodendrocytic progenitors is of utmost importance for cellular transplantologists. It seems that the use of progenitor cells and not fully differentiated cells or stem cells provides transplantologists with the greatest chance for therapeutic success: stem cells may choose a differentiation pathway other than planned by transplantologist, while mature cell, e.g. neurons, are quite sensitive to environmental changes. Determination of the progenitor type currently requires screening of expression of markers recognized as specific for particular cell type. Studies conducted for several years indicate that in the case of many markers this strategy is not appropriate. For example, the GFAP protein considered until recently a specific marker of astrocytes is also expressed in some neuronal stem cells. This discovery has led to a considerable chaos in the way cells are being defined. Furthermore, results of studies of the team where the author of this publication belongs indicate that stem cells may show coexpression of glial and neuronal markers. For the neuropoiesis model constructed upon this kind of data, a name “model of suppression of discordant phenotypes'’ has been proposed.
Modele neuropoezy pozwalają określać, na jakim etapie różnicowania znajdują się komórki neuralne. Modele te oddają stan naszej wiedzy o neuropoezie, niemniej mają również znaczenie praktyczne. Stwierdzenie w warunkach in vitro, czy neuralne komórki macierzyste różnicują się do progenitorów neuronalnych, astrocytarnych czy oligodendrocytarnych, jest bardzo ważne dla transplantologów komórkowych. Wydaje się bowiem, że stosowanie właśnie progenitorów, a nie komórek w pełni zróżnicowanych czy komórek macierzystych, daje transplantologom największe szanse na sukces terapeutyczny – komórki macierzyste mogą wybrać szlak różnicowania inny niż planowany przez transplantologa, natomiast komórki dojrzałe, takie jak np. neurony, nie są odporne na zmiany środowiska. Ustalenie, z jakim progenitorem mamy do czynienia, wymaga obecnie określenia ekspresji markerów uznawanych za specyficzne dla danych komórek. Badania prowadzone od kilku lat pokazują jednak, iż w przypadku wielu markerów taka strategia nie jest właściwa. Dla przykładu, białko GFAP uznawane do niedawna za marker astrocytów ulega ekspresji także w niektórych nerwowych komórkach macierzystych. Odkrycie to prowadzi do poważnego zamętu w sposobie definiowania komórek. Ponadto wyniki badań zespołu, do którego należy autor niniejszej publikacji, wskazują, że komórki macierzyste mogą wykazywać koekspresję markerów komórek glejowych i neuronalnych. Dla modelu neuropoezy skonstruowanego w oparciu o tego typu wyniki zaproponowano nazwę: „model supresji niespójnych fenotypów”.
Źródło:
Aktualności Neurologiczne; 2006, 6, 3; 164-168
1641-9227
2451-0696
Pojawia się w:
Aktualności Neurologiczne
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Identification of proteins associated with amyloidosis by polarity index method
Autorzy:
Polanco, Carlos
Samaniego, José
Uversky, Vladimir
Castañón-González, Jorge
Buhse, Thomas
Leopold-Sordo, Marili
Madero-Arteaga, Alejandro
Morales-Reyes, Alicia
Tavera-Sierra, Lourdes
González-Bernal, Jesus
Arias-Estrada, Miguel
Powiązania:
https://bibliotekanauki.pl/articles/1039130.pdf
Data publikacji:
2015
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
Polarity index method
natively unfolded proteins
intrinsically disordered proteins
natively folded proteins
neurons
amyloidosis
amyloid
amyloidogenic protein
Opis:
There is a natural protein form, insoluble and resistant to proteolysis, adopted by many proteins independently of their amino acid sequences via specific misfolding-aggregation process. This dynamic process occurs in parallel with or as an alternative to physiologic folding, generating toxic protein aggregates that are deposited and accumulated in various organs and tissues. These proteinaceous deposits typically represent bundles of β-sheet-enriched fibrillar species known as the amyloid fibrils that are responsible for serious pathological conditions, including but not limited to neurodegenerative diseases, grouped under the term amyloidoses. The proteins that might adopt this fibrillar conformation are some globular proteins and natively unfolded (or intrinsically disordered) proteins. Our work shows that intrinsically disordered and intrinsically ordered proteins can be reliably identified, discriminated, and differentiated by analyzing their polarity profiles generated using a computational tool known as the polarity index method (Polanco & Samaniego, 2009; Polanco et al., 2012; 2013; 2013a; 2014; 2014a; 2014b; 2014c; 2014d). We also show that proteins expressed in neurons can be differentiated from proteins in these two groups based on their polarity profiles, and also that this computational tool can be used to identify proteins associated with amyloidoses. The efficiency of the proposed method is high (i.e. 70%) as evidenced by the analysis of peptides and proteins in the APD2 database (2012), AVPpred database (2013), and CPPsite database (2013), the set of selective antibacterial peptides from del Rio et al. (2001), the sets of natively unfolded and natively folded proteins from Oldfield et al. (2005), the set of human revised proteins expressed in neurons, and non-human revised proteins expressed in neurons, from the Uniprot database (2014), and also the set of amyloidogenic proteins from the AmyPDB database (2014).
Źródło:
Acta Biochimica Polonica; 2015, 62, 1; 41-55
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Argeting neurons overcoming extra and intracellular barriers with biomaterial-based vectors to promote neuroprotection and neuroregeneration
Autorzy:
Pêgo, A. P.
Powiązania:
https://bibliotekanauki.pl/articles/284333.pdf
Data publikacji:
2018
Wydawca:
Akademia Górniczo-Hutnicza im. Stanisława Staszica w Krakowie. Polskie Towarzystwo Biominerałów
Tematy:
neurons
biomaterials
regeneration
Źródło:
Engineering of Biomaterials; 2018, 21, 148; 7
1429-7248
Pojawia się w:
Engineering of Biomaterials
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Can we build theories of understanding on the basis of mirror neurons?
Autorzy:
Pacholik-Żuromska, Anita
Powiązania:
https://bibliotekanauki.pl/articles/18687746.pdf
Data publikacji:
2015
Wydawca:
Uniwersytet Łódzki. Wydawnictwo Uniwersytetu Łódzkiego
Tematy:
mirror neurons
understanding
intentionality
self-reflection
concepts
self-knowledge
Opis:
The discovery of mirror neurons and the characterization of their response properties is certainly an important achievement in neurophysiology and cognitive neuroscience. The reference to the role of mirror neurons in ‘reading’ the intentions of other creatures and in the learning process fulfils an explanatory function in understanding many cognitive phenomena beginning from imitating, towards understanding, and finishing with complex social interactions. The focus of this paper is to review selected approaches to the role of mirror neurons in mental activity as understanding, and to conclude with some possible implications for researches on mirror neurons for philosophical theories of understanding.
Źródło:
Internetowy Magazyn Filozoficzny Hybris; 2015, 28, 1; 141-157
1689-4286
Pojawia się w:
Internetowy Magazyn Filozoficzny Hybris
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Koncepcja ucieleśnionego poznania w kognitywnej teorii filmu
The Concept of Embodied Cognition in Cognitive Film Theory
Autorzy:
Ostaszewski, Jacek
Powiązania:
https://bibliotekanauki.pl/articles/26850481.pdf
Data publikacji:
2022
Wydawca:
Polska Akademia Nauk. Instytut Sztuki PAN
Tematy:
kognitywna teoria filmu
przetwarzanie informacji
ucieleśnione poznanie
neurony lustrzane
reakcje autonomiczne
empatia
cognitive film theory
information processing
embodied cognition
mirror neurons
autonomic reactions
empathy
Opis:
Autor artykułu wyjaśnia źródła rozwoju kognitywnej teorii filmu. Przedstawia także dwie podstawowe orientacje w ramach nauki o procesach poznawczych – model poznania obliczeniowego i model poznania ucieleśnionego – które w teorii filmu funkcjonują jako dwie kolejne fazy. Model poznania ucieleśnionego jest wyjaśniany w kontekście zarówno tradycji myśli fenomenologicznej, jak i dokonań neuronauki, w tym odkrycia neuronów lustrzanych, które mimo kontrowersji stało się podstawą dla wielokierunkowej refleksji nad odbiorem filmów. Artykuł zawiera omówienie implementacji hipotezy o systemie lustrzanym do wyjaśniania przedpojęciowego odbioru filmu, z uwzględnieniem roli symulacji ucieleśnionej i empatii jako mechanizmów uczestnictwa w poznawczym i estetycznym doświadczaniu filmu. Przedstawione zostało także zagadnienie metodologiczne projektu estetyki naturalistycznej oraz możliwości syntezy podejścia kognitywnego i fenomenologicznego do wyjaśniania estetycznego doświadczania filmu.
The article explains the origins of the development of cognitive film theory. It also presents two basic orientations within cognitive science - the computational model of cognition and the embodied model of cognition – which function in film theory as two consecutive phases. The embodied model of cognition is explained in the context of both the tradition of phenomenological thought and the achievements of neuroscience, including the discovery of mirror neurons, which, despite the surrounding controversy, became the basis for multidirectional reflection on the reception of films. The article discusses the implementation of the mirror system hypothesis in the explication of the pre-conceptual film perception, including the role of embodied simulation and empathy as mechanisms of participation in cognitive and aesthetic film experience. The methodological issue of the naturalized aesthetics project as well as the possibilities of synthesizing the cognitive and phenomenological approach in the elucidation of the aesthetic reception of film are also presented.
Źródło:
Kwartalnik Filmowy; 2022, 119; 6-29
0452-9502
2719-2725
Pojawia się w:
Kwartalnik Filmowy
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Does senile impairment of cholinergic system in rats concern only disturbances in cholinergic phenotype or the progressive degeneration of neuronal cell bodies?
Autorzy:
Niewiadomska, Grażyna
Wyrzykowska, Jolanta
Chechłacz, Magdalena
Powiązania:
https://bibliotekanauki.pl/articles/1044354.pdf
Data publikacji:
2000
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
cholinergic neurons morphology and phenotype
aging
nerve growth factor
plasticity
basal forebrain
Opis:
The trophic effect of continuous intraventricular infusion of nerve growth factor (NGF) on morphology of the basal forebrain (BF) cholinergic neurons was tested in 4- and 28-month-old male Wistar rats. All studies were conducted using behaviorally uncharacterized animals from the same breeding colony. Immunohistochemical procedure for choline acetyltransferase (ChAT) and p75NTR receptor has been applied to identify cholinergic cells in the structures of basal forebrain (BF). Using a quantitative image analyzer, morphometric and densitometric parameters of ChAT- and p75NTR-positive cells were measured immediately after cessation of NGF infusion. In 28-month-old non-treated rats the number of intensively ChAT-positive cells in all forebrain structures was reduced by 50-70% as compared with young animals. The remaining ChAT-positive cells appeared shrunken and the neuropil staining was markedly reduced. In contrast, the same neurons when stained for p75NTR were numerous and distinctly visible with perfect morphology. Analysis of Nissl stained sections also showed that 28-month-old rats did not display significant losses of neuronal cell bodies. NGF restored the number of intensely stained ChAT-positive cells to about 90% of that for young controls and caused a significant increase in size of those cells in 28-month-old rats as compared with the control, age-matched group. NGF did not influence the morphology of p75NTR-positive neurons, which were well labeled, irrespective of treatment and age of the rats. In 4-month-old rats, NGF infusion decreased the intensity of both ChAT and p75NTR immunostaining. These data provide some evidence for preservation of BF cholinergic neurons from atrophy during aging and indicate that senile impairment of the cholinergic system in rats concerns decrease in ChAT-protein expression rather than an acute degeneration of neuronal cell bodies. Treatment with NGF resulted in restoration of cholinergic phenotype in the BF neurons of aged rats. However, the present study also rises issue of possible detrimental effects of NGF in young normal animals.
Źródło:
Acta Biochimica Polonica; 2000, 47, 2; 313-330
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Biologia czy kultura mózgu. W poszukiwaniu uwarunkowań działalności edukacyjnej
Autorzy:
Michalak, Renata
Powiązania:
https://bibliotekanauki.pl/articles/951753.pdf
Data publikacji:
2016
Wydawca:
Uniwersytet im. Adama Mickiewicza w Poznaniu
Tematy:
the biology of the brain
the culture of the brain
intelligence
mind
mirror neurons
education
Opis:
An unusual flowering neuroscience is perceived in many scientific areas and education also. The scientific disciplines such as neuropedagogic, neuroteaching or neuroprogramming are trying to use the data of neuroscience in optimizing educational process for children, teenagers, and adults. Improving the functions of human brain and maintaining its cognitive capacity are very important and attractive activities for both researchers and practitioners of education, now. However, it will not be possible without a good knowledge of the basics and the determinants of development of brain. This article presents neurobiological and cultural context of programming of educational process.
Źródło:
Kultura-Społeczeństwo-Edukacja; 2016, 10, 2; 95-100
2300-0422
Pojawia się w:
Kultura-Społeczeństwo-Edukacja
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Użyteczność modeli parametrycznych i sztucznych sieci neuronowych w prognozowaniu kosztów produkcji
The usefulness of parametric models and artificial neural networks in the estimation of production costs
Autorzy:
Leszczyński, Zbigniew
Jasiński, Tomasz
Powiązania:
https://bibliotekanauki.pl/articles/953077.pdf
Data publikacji:
2017
Wydawca:
Stowarzyszenie Księgowych w Polsce
Tematy:
model prognozowania kosztów
prognozowanie parametryczne
sztuczne sieci neuronowe
koszty prognozowane
model of cost estimation
parametric estimation
artificial neural neurons
estimated costs
Opis:
Celem artykułu jest analiza użyteczności modeli parametrycznych i sztucznych sieci neuronowych w prognozowaniu kosztów produkcji. Prognozowane koszty produkcji stanowią fundamentalną determinantę dla podejmowanych przez inżynierów decyzji technicznych i biznesowych związanych z zarządzaniem produkcją i kosztami produkcyjnymi. W pierwszej części artykułu przedstawiono ramy konceptualne budowy modelu prognozowania parametrycznego kosztów produkcji, wielowymiarowego o zależnościach liniowych i nieliniowych. Następnie omówiono istotę i zastosowanie sztucznych sieci neuronowych jako modelu – nieparametrycznego prognozowania kosztów produkcji. W obu częściach artykułu przeprowadzono badanie empiryczne z wykorzystaniem analizy regresji oraz sztucznych neuronów połączonych w sieci. Badanie empiryczne prezentuje procedury budowy modeli – parametrycznego i nieparametrycznego prognozowania kosztów produkcji oraz ich wady i zalety. W toku procedury badawczej przedstawiono zastosowanie analizowanych modeli prognozowania kosztów produkcji w określonym środowisku przemysłowym.
The aim of the paper is to analyze parametric models and artificial neural networks in terms of their suitability as estimation tools of the production costs. Estimated production costs are a fundamental determinant of the decision-making process by costs engineers relating to design and management costs of new products, infrastructure projects and production lines. The first part of the paper presents a conceptual framework for the construction of a model of production costs parametric estimation, multi-dimensional with linear and nonlinear dependency. It then discusses the nature and use of artificial neural networks as nonparametric estimates of production costs. In both parts of the article, an empirical study is conducted with the use of adequate statistical methods and artificial neurons. This study presents procedures for construction of models of parametric and nonparametric estimation of production costs and discusses their advantages and disadvantages. It also presents the application and usefulness of both models for estimating production costs in production environment.
Źródło:
Zeszyty Teoretyczne Rachunkowości; 2017, 91(147); 87-112
1641-4381
2391-677X
Pojawia się w:
Zeszyty Teoretyczne Rachunkowości
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Poeta zmysłów
A poet of the sence
Autorzy:
Łapiński, Zdzisław
Powiązania:
https://bibliotekanauki.pl/articles/16729485.pdf
Data publikacji:
2020-05-05
Wydawca:
Katolicki Uniwersytet Lubelski Jana Pawła II. Towarzystwo Naukowe KUL
Tematy:
ucieleśnienie
zmysły
neurony lustrzane
symulacja
alegoria
incarnation
senses
mirror neurons
simulation
allegory
Opis:
The article is an attempt to explain sensual depictions that are constantly present in Norwid’s works – albeit they are sometimes hidden – by means of cognitivistic categories. On the example of two texts two different ways are shown, in which these depictions are used by the poet. A fragment from the drama Cleopatra and Caesar illustrates Norwid’s technique of realistic description, and the poem Fate – the technique of allegory.
Źródło:
Studia Norwidiana; 2013, 31; 5-15
0860-0562
Pojawia się w:
Studia Norwidiana
Dostawca treści:
Biblioteka Nauki
Artykuł
Wyświetlanie 1-15 z 28

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