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Tytuł:
Argeting neurons overcoming extra and intracellular barriers with biomaterial-based vectors to promote neuroprotection and neuroregeneration
Autorzy:
Pêgo, A. P.
Powiązania:
https://bibliotekanauki.pl/articles/284333.pdf
Data publikacji:
2018
Wydawca:
Akademia Górniczo-Hutnicza im. Stanisława Staszica w Krakowie. Polskie Towarzystwo Biominerałów
Tematy:
neurons
biomaterials
regeneration
Źródło:
Engineering of Biomaterials; 2018, 21, 148; 7
1429-7248
Pojawia się w:
Engineering of Biomaterials
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Increased neurogenesis after ACEA and levetiracetam treatment in mouse pilocarpine model of epilepsy
Autorzy:
Zagaja, Mirosław
Szewczyk, Aleksandra
Haratym-Maj, Agnieszka
Rola, Radosław
Maj, Maciej
Łuszczki, Jarogniew J.
Anders-Mach, Marta
Powiązania:
https://bibliotekanauki.pl/articles/972512.pdf
Data publikacji:
2017
Wydawca:
Instytut Medycyny Wsi
Tematy:
neurogenesis
neurons
astrocytes
pilocarpine
ACEA
Levetiracetam
Opis:
Introduction and objectives. The aim of the study was to asses the impact of long-term therapy with the second generation antiepileptic drug levetiracetam (LEV) with arachidonyl-2’-chloroethylamide (ACEA), a highly selective cannabinoid CB1 receptor agoniston the process of neurogenesis in a mouse pilocarpine model of epilepsy (PILO). Additionally, a relationship was established between the treatment with ACEA in combination with LEV, and hippocampal neurogenesis in mouse PILO brain. Materials and method. All experiments were performed on adolescent male CB57/BL mice injected i.p. with LEV (10 mg/kg), ACEA (10 mg/kg) and PMSF (30 mg/kg) (phenylmethylsulfonyl fluoride — a substance protecting ACEA against degradation by the fatty-acid amidohydrolase), pilocarpine (PILO, a single dose 290 mg/kg) and methylscopolamine (30 min before PILO to stop the peripheral cholinergic effects of the pilocarpine, 1 mg/kg). The process of neurogenesis was evaluated after10 days treatment with LEV and ACEA. Results. Obtained results indicated that the combinations of ACEA+PMSF+LEV and ACEA +PMSF increased the total number of total newborn cells compared to the control. Moreover, ACEA+PMSF administered alone and in combination with LEV had a significant impact on neurogenesis increasing the total number of newborn neurons compared to the control group. Neither LEV nor PMSF had a significant impact on the number of proliferating cells and newborn neurons when compared to the control PILO group. In turn, LEV administered alone decreased significantly the number of astrocytes. However, ACEA+PMSF has demonstrated significant increase of astrocytes compare to control mice. Conclusions. These data provide substantial evidence that the combination of LEV+ACEA significantly increases the level of newborn neurons in the PILO dentate subgranular zone.
Źródło:
Journal of Pre-Clinical and Clinical Research; 2017, 11, 2; 136-141
1898-2395
Pojawia się w:
Journal of Pre-Clinical and Clinical Research
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Immunohistochemical characterization of nerve elements in porcine intrinsic laryngeal ganglia
Autorzy:
Sienkiewicz, W.
Klimczuk, M.
Gulbinowicz-Gowkielewicz, M.
Lepiarczyk, E.
Kaleczyc, J.
Powiązania:
https://bibliotekanauki.pl/articles/16539221.pdf
Data publikacji:
2022
Wydawca:
Polska Akademia Nauk. Czasopisma i Monografie PAN
Tematy:
larynx
intrinsic neurons
pig
immunohistochemistry
biologically active substances
Opis:
The present study investigated the chemical coding of neurons and nerve fibres in local laryngeal ganglia in pigs (n=5) using double-labelling immunohistochemistry. Virtually all the neurons were cholinergic in nature (ChAT- or VAChT-positive). Only very solitary, small nerve cells (presumably representing interneurons) stained intensely for adrenergic marker, DβH. Many neurons also contained immunoreactivity for NOS (91%), VIP (62.7%), NPY (24.7%), galanin (10%), SP (1.3%) and CGRP (5.3%). No neurons expressing somatostatin or Leu-enkephalin were observed. Nearly all the neuronal somata were densely supplied with varicose cholinergic nerve terminals, which presumably represented preganglionic axons, and some of them were also closely apposed with CGRP- and/or SP-positive varicose nerve endings, which were putative collaterals of extrinsic primary sensory fibres. In conclusion, this study has revealed that intrinsic neurons in the porcine larynx, like in many other mammalian species studied, should be classified as parasympathetic cholinergic neurons expressing biologically active substances, predominantly NOS and VIP. Furthermore, they are likely to receive inputs from not only preganglionic neurons but also primary sensory nerve cells. Finally, it appears that the information on the occurrence of the local laryngeal ganglia should be regularly included in textbooks dealing with the cranial portion of the parasympathetic nervous system in mammals.
Źródło:
Polish Journal of Veterinary Sciences; 2022, 25, 2; 325-334
1505-1773
Pojawia się w:
Polish Journal of Veterinary Sciences
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Dispersal and immunohistochemical characteristics of neurons in the stem of the porcine vagus nerve
Autorzy:
Sienkiewicz, W.
Klimczuk, M.
Majewska, M.
Kaleczyc, J.
Powiązania:
https://bibliotekanauki.pl/articles/16647386.pdf
Data publikacji:
2022
Wydawca:
Polska Akademia Nauk. Czasopisma i Monografie PAN
Tematy:
vagus nerve
intravagal neurons
neurotransmitter markers
immunohistochemistry
pig
Opis:
The present study investigated the distribution and chemical properties of nerve cell bodies within the trunk of the vagus nerve in juvenile female pigs (n=4) using double-labelling immunofluorescence. The neurons appeared mostly as single cells or formed streaks of cells or small ganglia. Many of the perikarya were cholinergic (VAChT-positive; VAChT+) or adrenergic (DβH+) in nature and no SP+ or CGRP+ neurons were encountered. There were no distinct left-right differences regarding the number and chemical coding of the neuronal somata, however, these characteristics significantly varied between particular nerve segments investigated. The vagosympathetic trunks, and thoracic and abdominal segments of the vagus nerve contained on average (the numerical values represent the means for both the left and right corresponding nerve segments) 142, 236, and 111 PGP 9.5-positive neurons, respectively. Proportions of cholinergic and adrenergic neurons were as follows: 0% and 100%, 54.2% and 33.2%, and 52.8% and 35.4%, respectively. Relatively many neurons in the thoracic and abdominal segments stained also for NOS (39.2% and 39.9%, respectively). It remains to be determined whether the porcine intravagal neurons represent a developmental relic, or whether they have any specific functional significance.
Źródło:
Polish Journal of Veterinary Sciences; 2022, 25, 4; 617-619
1505-1773
Pojawia się w:
Polish Journal of Veterinary Sciences
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Dense Wireless Network Inspired by the Nervous System
Autorzy:
Kułacz, Łukasz
Kliks, Adrian
Powiązania:
https://bibliotekanauki.pl/articles/226424.pdf
Data publikacji:
2020
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
dense wireless network
nervous system
neurons
glial cells
Opis:
This work presents concepts of the use of algorithms inspired by the functions and properties of the nervous system in dense wireless networks. In particular, selected features of the brain consisting of a large number of nerve connections were analyzed, which is why they are a good model for a dense network. In addition, the action of a selected cells from the nervous system (such as neuron, microglia or astrocyte) as well as phenomena observed in it (e.g. neuroplasticity) are presented.
Źródło:
International Journal of Electronics and Telecommunications; 2020, 66, 1; 93-98
2300-1933
Pojawia się w:
International Journal of Electronics and Telecommunications
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Can we build theories of understanding on the basis of mirror neurons?
Autorzy:
Pacholik-Żuromska, Anita
Powiązania:
https://bibliotekanauki.pl/articles/18687746.pdf
Data publikacji:
2015
Wydawca:
Uniwersytet Łódzki. Wydawnictwo Uniwersytetu Łódzkiego
Tematy:
mirror neurons
understanding
intentionality
self-reflection
concepts
self-knowledge
Opis:
The discovery of mirror neurons and the characterization of their response properties is certainly an important achievement in neurophysiology and cognitive neuroscience. The reference to the role of mirror neurons in ‘reading’ the intentions of other creatures and in the learning process fulfils an explanatory function in understanding many cognitive phenomena beginning from imitating, towards understanding, and finishing with complex social interactions. The focus of this paper is to review selected approaches to the role of mirror neurons in mental activity as understanding, and to conclude with some possible implications for researches on mirror neurons for philosophical theories of understanding.
Źródło:
Internetowy Magazyn Filozoficzny Hybris; 2015, 28, 1; 141-157
1689-4286
Pojawia się w:
Internetowy Magazyn Filozoficzny Hybris
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Neuroplasticity and Microglia Functions Applied in Dense Wireless Networks
Autorzy:
Kułacz, Łukasz
Kliks, Adrian
Powiązania:
https://bibliotekanauki.pl/articles/308840.pdf
Data publikacji:
2019
Wydawca:
Instytut Łączności - Państwowy Instytut Badawczy
Tematy:
ad-hoc network
brain inspired communication
glial cells
neurons
Opis:
This paper presents developments in the area of brain-inspired wireless communications relied upon in dense wireless networks. Classic approaches to network design are complemented, firstly, by the neuroplasticity feature enabling to add the learning ability to the network. Secondly, the microglia ability enabling to repair a network with damaged neurons is considered. When combined, these two functionalities guarantee a certain level of fault-tolerance and self-repair of the network. This work is inspired primarily by observations of extremely energy efficient functions of the brain, and of the role that microglia cells play in the active immune defense system. The concept is verified by computer simulations, where messages are transferred through a dense wireless network based on the assumption of minimized energy consumption. Simulation encompasses three different network topologies which show the impact that the location of microglia nodes and their quantity exerts on network performance. Based on the results achieved, some algorithm improvements and potential future work directions have been identified.
Źródło:
Journal of Telecommunications and Information Technology; 2019, 1; 39-46
1509-4553
1899-8852
Pojawia się w:
Journal of Telecommunications and Information Technology
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Enteric neuronal development in canine small intestine – an immunohistochemical study
Autorzy:
Serzysko, T.
Skwarek, A.
Chudziak, E.
Malina, M.
Kaleczyc, J.
Sienkiewicz, W.
Powiązania:
https://bibliotekanauki.pl/articles/2087175.pdf
Data publikacji:
2021
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
dog
fetus
small intestine
enteric nervous system
development
neurons
immunohistochemistry
Źródło:
Polish Journal of Veterinary Sciences; 2021, 24, 2; 293-301
1505-1773
Pojawia się w:
Polish Journal of Veterinary Sciences
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Application of NucleoCounter for the comprehensive assessment of murine cultured neurons during infection with Equine Herpesvirus type 1 (EHV-1)
Autorzy:
Chodkowski, M.
Serafińska, I.
Brzezicka, J.
Bańbura, M.W.
Cymerys, J.
Powiązania:
https://bibliotekanauki.pl/articles/2087859.pdf
Data publikacji:
2017
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
NucleoCounter NC-3000
viability
cell cycle
apoptosis
neurons
EHV-1
Źródło:
Polish Journal of Veterinary Sciences; 2017, 4; 831-834
1505-1773
Pojawia się w:
Polish Journal of Veterinary Sciences
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Perception-based reasoning: evaluation systems
Autorzy:
Rutkowska, D.
Powiązania:
https://bibliotekanauki.pl/articles/1931577.pdf
Data publikacji:
2003
Wydawca:
Politechnika Gdańska
Tematy:
fuzzy sets
perception-based systems
fuzzy neurons
neural networks
artificial intelligence
Opis:
A perception-based interpretation of evaluation systems is proposed in this paper. Thus, a perception-based approach to create intelligent systems is considered. The evaluation systems can be employed eg. in order to assess student exams, as well as to other applications. Evaluation marks used in these systems are given as perceptions expressed by words. The words play the role of labels of perceptions, and are represented by fuzzy sets. This means that the idea of perception-based systems, introduced by Zadeh, is applied. Various algorithms of overall assessment are suggested in this paper. Overall evaluation is produced as an aggregation of component evaluation marks. Systems of this kind can be obtained using fuzzy neurons, so fuzzy neural networks are also mentioned as a method of perception-based reasoning. The usefulness in artificial intelligence of both fuzzy sets and neural networks, and especially a combination of these, is shown.
Źródło:
TASK Quarterly. Scientific Bulletin of Academic Computer Centre in Gdansk; 2003, 7, 1; 131-145
1428-6394
Pojawia się w:
TASK Quarterly. Scientific Bulletin of Academic Computer Centre in Gdansk
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Poeta zmysłów
A poet of the sence
Autorzy:
Łapiński, Zdzisław
Powiązania:
https://bibliotekanauki.pl/articles/16729485.pdf
Data publikacji:
2020-05-05
Wydawca:
Katolicki Uniwersytet Lubelski Jana Pawła II. Towarzystwo Naukowe KUL
Tematy:
ucieleśnienie
zmysły
neurony lustrzane
symulacja
alegoria
incarnation
senses
mirror neurons
simulation
allegory
Opis:
The article is an attempt to explain sensual depictions that are constantly present in Norwid’s works – albeit they are sometimes hidden – by means of cognitivistic categories. On the example of two texts two different ways are shown, in which these depictions are used by the poet. A fragment from the drama Cleopatra and Caesar illustrates Norwid’s technique of realistic description, and the poem Fate – the technique of allegory.
Źródło:
Studia Norwidiana; 2013, 31; 5-15
0860-0562
Pojawia się w:
Studia Norwidiana
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Does senile impairment of cholinergic system in rats concern only disturbances in cholinergic phenotype or the progressive degeneration of neuronal cell bodies?
Autorzy:
Niewiadomska, Grażyna
Wyrzykowska, Jolanta
Chechłacz, Magdalena
Powiązania:
https://bibliotekanauki.pl/articles/1044354.pdf
Data publikacji:
2000
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
cholinergic neurons morphology and phenotype
aging
nerve growth factor
plasticity
basal forebrain
Opis:
The trophic effect of continuous intraventricular infusion of nerve growth factor (NGF) on morphology of the basal forebrain (BF) cholinergic neurons was tested in 4- and 28-month-old male Wistar rats. All studies were conducted using behaviorally uncharacterized animals from the same breeding colony. Immunohistochemical procedure for choline acetyltransferase (ChAT) and p75NTR receptor has been applied to identify cholinergic cells in the structures of basal forebrain (BF). Using a quantitative image analyzer, morphometric and densitometric parameters of ChAT- and p75NTR-positive cells were measured immediately after cessation of NGF infusion. In 28-month-old non-treated rats the number of intensively ChAT-positive cells in all forebrain structures was reduced by 50-70% as compared with young animals. The remaining ChAT-positive cells appeared shrunken and the neuropil staining was markedly reduced. In contrast, the same neurons when stained for p75NTR were numerous and distinctly visible with perfect morphology. Analysis of Nissl stained sections also showed that 28-month-old rats did not display significant losses of neuronal cell bodies. NGF restored the number of intensely stained ChAT-positive cells to about 90% of that for young controls and caused a significant increase in size of those cells in 28-month-old rats as compared with the control, age-matched group. NGF did not influence the morphology of p75NTR-positive neurons, which were well labeled, irrespective of treatment and age of the rats. In 4-month-old rats, NGF infusion decreased the intensity of both ChAT and p75NTR immunostaining. These data provide some evidence for preservation of BF cholinergic neurons from atrophy during aging and indicate that senile impairment of the cholinergic system in rats concerns decrease in ChAT-protein expression rather than an acute degeneration of neuronal cell bodies. Treatment with NGF resulted in restoration of cholinergic phenotype in the BF neurons of aged rats. However, the present study also rises issue of possible detrimental effects of NGF in young normal animals.
Źródło:
Acta Biochimica Polonica; 2000, 47, 2; 313-330
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Neurophysiological changes in the afferent somatosensory system indices in the case of vertebrogenic spine pathology in miners
Autorzy:
Battakova, Sharbanu
Shraimanov, Bekkair
Powiązania:
https://bibliotekanauki.pl/articles/2179775.pdf
Data publikacji:
2013-04-01
Wydawca:
Instytut Medycyny Pracy im. prof. dra Jerzego Nofera w Łodzi
Tematy:
miners
vertebral pathology
pain syndrome
Somatosensory Stimulated Potential (SSP)
pain reception
afferent neurons
Opis:
Objectives: The aim of the paper was to prove that job conditions impact the state of the afferent part of the somatosensory system in miners. Materials and Methods: Data analysis of the electrophysiological examination of the syndrome in 148 patients, aged from 28 to 55 years, with a mild, moderate and severe degree of the pain syndrome was performed. The control group included 28 people without any pain symptoms. The method used was that of somatosensory stimulated potential (SSP) with the potentials amplitude and latency main components taken into consideration. Results: It was proven that the true decrease of the somatosensory stimulated potential SSP N22 (p < 0.05) component amplitudes by 41%; N30 component amplitude tend to decrease by 26%. This proves that the true N22 (p < 0.01) component latency increase by 63.8% corresponds to afferent excitation wave conductibility under the pain syndrome of vertebral pathology through sensitivity pathways mainly in the posterior spinal cord columns and then, through the parts of the brain stem, involving the cerebral cortex, which is confirmed by the fact that the P38 and P46 components amplitudes tend to decrease. In addition to this, the proven N10–N13 (p < 0.05), N13–N20 (p < 0.05), N10–N20 (p < 0.05) intervals increases by 43.5–41.8–38.7%, respectively, correspond to the nervous impulse conductibility through the peripheral nervous system structures and allow to reveal the subclinical slowdown of impulse conductibility, which indicates that the conducting system is changed even under a mild pain syndrome. Conclusions: It was found that the data obtained allow for the better understanding of how the neuropathological pain syndrome under vertebral spine pathology is formed.
Źródło:
International Journal of Occupational Medicine and Environmental Health; 2013, 26, 2; 230-234
1232-1087
1896-494X
Pojawia się w:
International Journal of Occupational Medicine and Environmental Health
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
What can a mathematician do in neuroscience?
Autorzy:
Karbowski, Jan
Powiązania:
https://bibliotekanauki.pl/articles/748768.pdf
Data publikacji:
2012
Wydawca:
Polskie Towarzystwo Matematyczne
Tematy:
mózg, modelowanie systemu nerwowego, neurobiologia obliczeniowa, neurony, procesy mózgowe
Computational Neuroscience
Brain, Modeling, Neurons
Opis:
Mózg ssaków jest jednym z najbardziej złozonych obiektów we wszechswiecie. Jest odpowiedzialny za sterowanie wszystkimi aspektami zachowan zwierzecia i człowieka. Obecnie usprawiedliwione wydaje sie stwierdzenie, ze nasza wiedza na temat pracy mózgu i jego funkcjach jest dosc ograniczona. Neurobiologia obliczeniowa jest dyscyplina naukowa, która próbuje zrozumiec i opisac mózg w kategoriach modelowania matematycznego. W tej pracy zawarto przyjazny dla czytelnika przeglad zagadnien, który ma na celu wprowadzenie w ten stosunkowo nowy dla matematyków i fizyków obszar badawczy, pokazujac przykłady najnowszych trendów w tej dziedzinie. Artykuł omawia takze krótko przyszłe perspektywy dla budowy zintegrowanej teorii funkcji mózgu.
Mammalian brain is one of the most complex objects in the known universe, as it governs every aspect of animal’s and human behavior. It is fair to say that we have a very limited knowledge of how the brain operates and functions. Computational Neuroscience is a scientific discipline that attempts to understand and describe the brain in terms of mathematical modeling. This user-friendly review tries to introduce this relatively new field to mathematicians and physicists by showing examples of recent trends. It also discusses briefly future prospects for constructing an integrated theory of brain function.
Źródło:
Mathematica Applicanda; 2012, 40, 1
1730-2668
2299-4009
Pojawia się w:
Mathematica Applicanda
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Historia sztuki i medycyna
Art history and medicine
Autorzy:
Kędziora, Łukasz
Powiązania:
https://bibliotekanauki.pl/articles/1041322.pdf
Data publikacji:
2019-01-11
Wydawca:
Uniwersytet im. Adama Mickiewicza w Poznaniu
Tematy:
neuroesthetics
embodied simulation
mirror neurons
Zoe Leonard
Wilhelm Sasnal
art
medicine
art history
empathy
Opis:
The article Art history and medicine concerns selected aspects of the Medicine in art exhibition, taking place at the Museum of Contemporary Art in Kraków (MOCAK) between 22nd April and 22nd October 2016. The author discusses the issue of medicine with regard to its mechanisms that let us create and perceive art. This reflection includes a historical overview of the “medically-oriented” art research. Another significant aspect constitutes the attempt to explain by the tools associated with neuroaesthetics, why the viewers are likely to look at some drastic images created by artists with such willingness and involvement. The analysis refers to texts by D. Freedberg, V. Gallese, A. Damasio, P. Przybysz, and others. It also includes interpretations of the photohraph Seated anatomical model by Zoe Leonard, as well as the Medical Kit installation by Wilhelm Sasnal.
Źródło:
Poznańskie Studia Polonistyczne. Seria Literacka; 2018, 34; 341-356
1233-8680
2450-4947
Pojawia się w:
Poznańskie Studia Polonistyczne. Seria Literacka
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Interactions between art, architecture and CNS functions
Interakcje pomiędzy sztuką i architekturą, a funkcjonowaniem OUN (ośrodkowego układu nerwowego)
Autorzy:
Bil, J. S.
Łabuz-Roszak, B.
Gorczyca, P. W.
Powiązania:
https://bibliotekanauki.pl/articles/370564.pdf
Data publikacji:
2017
Wydawca:
Zachodniopomorski Uniwersytet Technologiczny w Szczecinie. Wydawnictwo Uczelniane ZUT w Szczecinie
Tematy:
architecture
mirror neurons
neuroscience
physiology
Theory of Mind
architektura
fizjologia neuronauka
neurony lustrzane
teoria umysłu
Opis:
The theories, which help to understand a connection between neuroscience and architecture, are the theory of mirror neurons and the Theory of Mind (ToM). They attempt to explain how, the built environment influences human emotions, behavioural and physiological reactions, and also social relations. It helps to understand the origins of empathy and emotions with both social and anthropomorphic environment.
Teorie, które pomagają zrozumieć związek pomiędzy neurobiologią a architekturą, to teorie neuronów lustrzanych i teoria umysłu (ToM). Próbują wytłumaczyć, jak zbudowane środowisko wpływa na ludzkie emocje, reakcje behawioralne i fizjologiczne, a także na stosunki społeczne. Definiują podstawę empatii i emocji oraz relacje z otoczeniem.
Źródło:
Przestrzeń i Forma; 2017, 30; 75-86
1895-3247
2391-7725
Pojawia się w:
Przestrzeń i Forma
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Biologia czy kultura mózgu. W poszukiwaniu uwarunkowań działalności edukacyjnej
Autorzy:
Michalak, Renata
Powiązania:
https://bibliotekanauki.pl/articles/951753.pdf
Data publikacji:
2016
Wydawca:
Uniwersytet im. Adama Mickiewicza w Poznaniu
Tematy:
the biology of the brain
the culture of the brain
intelligence
mind
mirror neurons
education
Opis:
An unusual flowering neuroscience is perceived in many scientific areas and education also. The scientific disciplines such as neuropedagogic, neuroteaching or neuroprogramming are trying to use the data of neuroscience in optimizing educational process for children, teenagers, and adults. Improving the functions of human brain and maintaining its cognitive capacity are very important and attractive activities for both researchers and practitioners of education, now. However, it will not be possible without a good knowledge of the basics and the determinants of development of brain. This article presents neurobiological and cultural context of programming of educational process.
Źródło:
Kultura-Społeczeństwo-Edukacja; 2016, 10, 2; 95-100
2300-0422
Pojawia się w:
Kultura-Społeczeństwo-Edukacja
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
W poszukiwaniu korzeni języka naturalnego – intencjonalna komunikacja u naczelnych różnych od człowieka
Searching for the roots of natural language: intentional communication among non-human primates
Autorzy:
Kwiatek, Łukasz
Powiązania:
https://bibliotekanauki.pl/articles/690826.pdf
Data publikacji:
2014
Wydawca:
Copernicus Center Press
Tematy:
Michael Tomasello
Michael Arbib
language
communication
intentionality
mirror neurons
vocalizations
gestures
cultural evolution
biological evolution
Opis:
Where should we seek the roots of natural language? Common sense suggests that human language should have somehow evolved from primitive vocal communication, which is also, to some extent, present among other animals, especially since primary humans mean of communication is speech. Some biological and psychological evidences, however, both from observation and experiments, indicate that for the missing evolutionary link between human language and animal (apes) communication one should take chimpanzee gestural communication, the only undoubtedly intentional non-human mean of communication. In this paper, I present the evidences for the aforementioned theory and draw some conclusions regarding the issue of two “sources” of language – biological and cultural evolution.
Źródło:
Zagadnienia Filozoficzne w Nauce; 2014, 55; 43-73
0867-8286
2451-0602
Pojawia się w:
Zagadnienia Filozoficzne w Nauce
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Przeciw empatii – Sartre i Gombrowicz, czyli jak filozofia i literatura wyprzedzają koncepcje naukowe
Autorzy:
Cieliczko, Małgorzata
Powiązania:
https://bibliotekanauki.pl/articles/437580.pdf
Data publikacji:
2014
Wydawca:
Uniwersytet Pedagogiczny im. Komisji Edukacji Narodowej w Krakowie. Instytut Filozofii i Socjologii
Tematy:
body
corporeality
being
empathy
compassion
identification
interpersonal relations
mirror neurons
Jean Paul Sartre
Witold Gombrowicz
Opis:
The article presents Jean Paul Sartre’s idea of the human body and the bodiliness described in his book Being and nothingness (1943). In this book, Sartre argued that every human relation is based on the objectification of one human by another, and entering into empathic contactis basically impossible. The author of the article has confronted this thesis with contemporary psychological and neuropsychological thought (mirror neuron theory) and has investigated how the category of empathy functions in literary studies. A very important part of this article is the reflection on the presence and topicality of Sartre’s beliefs in the literature. The author has conducted an interpretation of Witold Gombrowicz’s story Tancerz mecenasa Kraykowskiego (1926) from the collection Bakakaj (1957), and has shown that the ideas presented by Sartre are reflected there in a very interesting way. Sartre’s philosophy turns out to be absolutely up‑to‑date right now, more than many psychological theories — it not only supplies a philosophical base for the analysis of human relations (those also presented in literature), but also gives a certain tool for describing them in the form of specific language and terminology.
Źródło:
ARGUMENT: Biannual Philosophical Journal; 2014, 4, 2; 359-374
2083-6635
2084-1043
Pojawia się w:
ARGUMENT: Biannual Philosophical Journal
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
The expression of androgen receptor in neurons of the anterior pelvic ganglion and celiac-superior mesenteric ganglion in the male pig
Autorzy:
Kaleczyc, J.
Kasica-Jarosz, N.
Pidsudko, Z.
Przyborowska, A.
Sienkiewicz, W.
Powiązania:
https://bibliotekanauki.pl/articles/2087598.pdf
Data publikacji:
2019
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
androgen receptor
neurons
anterior pelvic ganglion
celiac-superior mesenteric ganglion
quantitative real-time PCR
immunohistochemistry
male pig
Źródło:
Polish Journal of Veterinary Sciences; 2019, 1; 151-155
1505-1773
Pojawia się w:
Polish Journal of Veterinary Sciences
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
„Ludzki mózg jest potężną imitującą maszyną”. Teoria mimetyczna a badania nad naturą imitacji w naukach kognitywnych
“Human Brain is a Powerful Imitating Machine” Mimetic Theory and Research on the Nature of Imitation in Cognitive Sciences
Autorzy:
Strączek, Bogumił
Powiązania:
https://bibliotekanauki.pl/articles/495027.pdf
Data publikacji:
2016-09-30
Wydawca:
Towarzystwo Naukowe Franciszka Salezego
Tematy:
mimesis;
teoria mimetyczna;
psychologia rozwojowa;
nauki kognitywne;
neurony lustrzane;
mimetic theory;
developmental psychology;
cognitive science;
mirror neurons;
Opis:
This article attempts to trace the relationship between René Girard’s mimetic theory and re- search on the nature of imitation in cognitive sciences. It is divided into four parts. The first one defines the basic concept of the French thinker’s theory, i.e. that of mimetic desire, in the context of such notions as biological, cultural and psychological mimicry. The second refers to the research conducted in the area of developmental psychology on mimetic behaviours of infants. The third part shows how imitative behaviours are reflected in the activity of neurons. The fourth chapter describes the most recent findings, which directly relate to the theory of René Girard’s mimetic desire.
Źródło:
Seminare. Poszukiwania naukowe; 2016, 37, 3; 47-60
1232-8766
Pojawia się w:
Seminare. Poszukiwania naukowe
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Identification of proteins associated with amyloidosis by polarity index method
Autorzy:
Polanco, Carlos
Samaniego, José
Uversky, Vladimir
Castañón-González, Jorge
Buhse, Thomas
Leopold-Sordo, Marili
Madero-Arteaga, Alejandro
Morales-Reyes, Alicia
Tavera-Sierra, Lourdes
González-Bernal, Jesus
Arias-Estrada, Miguel
Powiązania:
https://bibliotekanauki.pl/articles/1039130.pdf
Data publikacji:
2015
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
Polarity index method
natively unfolded proteins
intrinsically disordered proteins
natively folded proteins
neurons
amyloidosis
amyloid
amyloidogenic protein
Opis:
There is a natural protein form, insoluble and resistant to proteolysis, adopted by many proteins independently of their amino acid sequences via specific misfolding-aggregation process. This dynamic process occurs in parallel with or as an alternative to physiologic folding, generating toxic protein aggregates that are deposited and accumulated in various organs and tissues. These proteinaceous deposits typically represent bundles of β-sheet-enriched fibrillar species known as the amyloid fibrils that are responsible for serious pathological conditions, including but not limited to neurodegenerative diseases, grouped under the term amyloidoses. The proteins that might adopt this fibrillar conformation are some globular proteins and natively unfolded (or intrinsically disordered) proteins. Our work shows that intrinsically disordered and intrinsically ordered proteins can be reliably identified, discriminated, and differentiated by analyzing their polarity profiles generated using a computational tool known as the polarity index method (Polanco & Samaniego, 2009; Polanco et al., 2012; 2013; 2013a; 2014; 2014a; 2014b; 2014c; 2014d). We also show that proteins expressed in neurons can be differentiated from proteins in these two groups based on their polarity profiles, and also that this computational tool can be used to identify proteins associated with amyloidoses. The efficiency of the proposed method is high (i.e. 70%) as evidenced by the analysis of peptides and proteins in the APD2 database (2012), AVPpred database (2013), and CPPsite database (2013), the set of selective antibacterial peptides from del Rio et al. (2001), the sets of natively unfolded and natively folded proteins from Oldfield et al. (2005), the set of human revised proteins expressed in neurons, and non-human revised proteins expressed in neurons, from the Uniprot database (2014), and also the set of amyloidogenic proteins from the AmyPDB database (2014).
Źródło:
Acta Biochimica Polonica; 2015, 62, 1; 41-55
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Application of Neural Networksin the Tests of Hand Grenade Fuses
Zastosowanie sieci neuronowych w badaniach zapalników do granatów ręcznych
Autorzy:
Ampuła, Dariusz
Powiązania:
https://bibliotekanauki.pl/articles/208533.pdf
Data publikacji:
2019
Wydawca:
Wojskowa Akademia Techniczna im. Jarosława Dąbrowskiego
Tematy:
artificial intelligence
neural networks
activation function
hidden neurons
fuse
sztuczna inteligencja
sieci neuronowe
funkcja aktywacji
neurony ukryte
zapalnik
Opis:
The neural networks, which find currently use in the unusually wide range of problems, in such fields as: finance, medicine, geology or physics, were characterized in the article. It was accent, that neural networks are very sophisticated technique of modelling, able to map extremely complex functions. It was noticed particularly, that neural networks had a non-linear character, what very essentially improve the possibilities of their applications. Some previous applications of neural networks were introduced, both in the area of domestic and foreign, including also military applications. The fuse of UZRGM type (Universal Modernized Fuse of Hand Grenades) was characterized, describing his building and way of action, special attention-getting on the tested features during laboratory diagnostic tests. Necessary technical parameters for the first and the second laboratory diagnostic tests, whose purpose was to build two independent neural networks, on the basis of existing test results and undertaken post-diagnostic decisions were designed. A few artificial neural networks were made and finally the best two independent neural networks were chosen. The main parameters of the chosen active neural networks were introduced in the pictures. Concise information, relating to the built artificial neural networks, for the first and the second laboratory diagnostic tests of the fuses of UZRGM type, was presented in the end of the article. In the summary, clearly distinguished are advantages of the applications of the proposed evaluation method, which significantly shortens an evaluation process of new empirical test results and causes complex automatization of an evaluation process of the tested fuses.
W artykule scharakteryzowano sieci neuronowe, które znajdują obecnie zastosowanie w niezwykle wielu problemach, w takich dziedzinach jak: finanse, medycyna, geologia czy fizyka. Podkreślono, że sieci neuronowe są bardzo wyrafinowaną techniką modelowania, zdolną do odwzorowania nadzwyczaj złożonych funkcji. W szczególności zauważono, że sieci te mają charakter nieliniowy, co bardzo istotnie wzbogaca możliwości ich zastosowania. Przedstawiono niektóre dotychczasowe zastosowania sieci neuronowych, zarówno w obszarze krajowym, jak i zagranicznym, włączając w to także zastosowania wojskowe. Scharakteryzowano zapalnik typu UZRGM, opisując jego budowę oraz sposób działania, zwrócono szczególną uwagę na badane cechy podczas laboratoryjnych badań diagnostycznych. Zaprojektowano niezbędne parametry techniczne dla pierwszych i drugich laboratoryjnych badań diagnostycznych, których celem była budowa dwóch niezależnych sieci neuronowych na podstawie istniejących wyników badań oraz podjętych decyzji podiagnostycznych. Zbudowano wiele sztucznych sieci neuronowych, których wynikiem były zaprojektowane i wybrane jako najlepsze dwie niezależne sieci neuronowe. Na rysunkach przedstawiono główne parametry wybranych aktywnych sieci neuronowych. Na końcu artykułu znajdują się zwięzłe informacje dotyczące zbudowanych sztucznych sieci neuronowych dla pierwszych i drugich laboratoryjnych badań diagnostycznych zapalników typu UZRGM. W podsumowaniu jasno wyróżniono zalety stosowania zaproponowanej metody oceny, która znacząco skraca proces oceny nowych empirycznych wyników badań oraz powoduje pełną automatyzację procesu oceny badanych zapalników.
Źródło:
Biuletyn Wojskowej Akademii Technicznej; 2019, 68, 1; 197-212
1234-5865
Pojawia się w:
Biuletyn Wojskowej Akademii Technicznej
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Czy potrzebny jest nowy model neuropoezy?
Do we need a new model of neuropoiesis?
Autorzy:
Rieske, Piotr
Powiązania:
https://bibliotekanauki.pl/articles/1061273.pdf
Data publikacji:
2006
Wydawca:
Medical Communications
Tematy:
astrocytes
astrocyty
neural stem cells
neurons
neuropoiesis
suppression of discordant phenotypes
neurony
neuropoeza
supresja niespójnych fenotypów
neuralne komórki macierzyste
Opis:
Models of neuropoiesis make it possible to determine at what stage of differentiation are neuronal cells. These models reflect our current knowledge about neuropoiesis, but they have also practical significance. In vitro determination whether neuronal stem cells differentiate to neuronal, astrocytic or oligodendrocytic progenitors is of utmost importance for cellular transplantologists. It seems that the use of progenitor cells and not fully differentiated cells or stem cells provides transplantologists with the greatest chance for therapeutic success: stem cells may choose a differentiation pathway other than planned by transplantologist, while mature cell, e.g. neurons, are quite sensitive to environmental changes. Determination of the progenitor type currently requires screening of expression of markers recognized as specific for particular cell type. Studies conducted for several years indicate that in the case of many markers this strategy is not appropriate. For example, the GFAP protein considered until recently a specific marker of astrocytes is also expressed in some neuronal stem cells. This discovery has led to a considerable chaos in the way cells are being defined. Furthermore, results of studies of the team where the author of this publication belongs indicate that stem cells may show coexpression of glial and neuronal markers. For the neuropoiesis model constructed upon this kind of data, a name “model of suppression of discordant phenotypes'’ has been proposed.
Modele neuropoezy pozwalają określać, na jakim etapie różnicowania znajdują się komórki neuralne. Modele te oddają stan naszej wiedzy o neuropoezie, niemniej mają również znaczenie praktyczne. Stwierdzenie w warunkach in vitro, czy neuralne komórki macierzyste różnicują się do progenitorów neuronalnych, astrocytarnych czy oligodendrocytarnych, jest bardzo ważne dla transplantologów komórkowych. Wydaje się bowiem, że stosowanie właśnie progenitorów, a nie komórek w pełni zróżnicowanych czy komórek macierzystych, daje transplantologom największe szanse na sukces terapeutyczny – komórki macierzyste mogą wybrać szlak różnicowania inny niż planowany przez transplantologa, natomiast komórki dojrzałe, takie jak np. neurony, nie są odporne na zmiany środowiska. Ustalenie, z jakim progenitorem mamy do czynienia, wymaga obecnie określenia ekspresji markerów uznawanych za specyficzne dla danych komórek. Badania prowadzone od kilku lat pokazują jednak, iż w przypadku wielu markerów taka strategia nie jest właściwa. Dla przykładu, białko GFAP uznawane do niedawna za marker astrocytów ulega ekspresji także w niektórych nerwowych komórkach macierzystych. Odkrycie to prowadzi do poważnego zamętu w sposobie definiowania komórek. Ponadto wyniki badań zespołu, do którego należy autor niniejszej publikacji, wskazują, że komórki macierzyste mogą wykazywać koekspresję markerów komórek glejowych i neuronalnych. Dla modelu neuropoezy skonstruowanego w oparciu o tego typu wyniki zaproponowano nazwę: „model supresji niespójnych fenotypów”.
Źródło:
Aktualności Neurologiczne; 2006, 6, 3; 164-168
1641-9227
2451-0696
Pojawia się w:
Aktualności Neurologiczne
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Hipoteza rozbitego lustra a trudności rozwijania teorii umysłu u osób ze spektrum autyzmu - przegląd literatury i aktualny stan badań
Hypothesis of a Broken Mirror versus Difficulties of Developing Mind Theory in People Suffering from Autism Spectrum - Literature Review and Current Research Status
Autorzy:
Głowacka, Karolina
Powiązania:
https://bibliotekanauki.pl/articles/2140132.pdf
Data publikacji:
2019-06-30
Wydawca:
Wydawnictwo Naukowe Dolnośląskiej Szkoły Wyższej
Tematy:
autyzm
teoria rozbitego lustra
neurony lustrzane
teoria umysłu
autism
“the theory of a broken mirror”
mirror neurons
mind theory
Opis:
Zaburzenia ze spektrum autyzmu (ASD) są coraz częściej uznawane za ważną przyczynę niepełnosprawności społecznej i były przedmiotem intensywnego rozwoju badań w ostatnim dziesięcioleciu. Zestawienie niektórych odkryć psychologicznych z nowymi odkryciami w dziedzinie neurobiologii daje perspektywę nowego i potencjalnie silnego modelu zarówno wczesnego funkcjonowaniaspołecznego, jak i zaburzeń z nim związanych, między innymi z autyzmem. Zdolność do zrozumienia celów i zamiarów stojących za działaniami innych ludzi ma kluczowe znaczenie dla wielu interakcji społecznych. Wziąwszy pod uwagę głębokie trudności społeczne obserwowane w autyzmie, możemy oczekiwać pogorszenia zrozumienia celów u osób z zaburzeniami autyzmu. Dwie wpływowe teorie, „teoria rozbitego lustra” i teoria mentalizmu mogą przewidzieć ten wynik.
Disorders from autism spectrum are more and more often recognised as an important cause of social disability and they have been a subject of a rapid research development during the last decade. Combining some psychological discoveries with latest discoveries in neurobiology gives a perspective of a new and potentially strong model of both social functioning and disorders connected therewith, amongst others, with autism. The ability to understand aims and plans behind other people’s actions have a crucial meaning for many social interactions. Taking into account deep social difficulties observed in autism one can expect the deterioration of understanding the goals of people suffering from autism disorders. Two influential theories: “the theory of a broken mirror” and the theory of mentalism may predict that result.
Źródło:
Teraźniejszość – Człowiek – Edukacja; 2019, 22, 2(86); 41-56
1505-8808
2450-3428
Pojawia się w:
Teraźniejszość – Człowiek – Edukacja
Dostawca treści:
Biblioteka Nauki
Artykuł
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