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    Wyświetlanie 1-7 z 7
    Tytuł:
    Duration of breastfeeding and psychomotor development in 1-year-old children – Polish Mother and Child Cohort Study
    Autorzy:
    Stelmach, Iwona
    Kwarta, Paulina
    Jerzyńska, Joanna
    Stelmach, Włodzimierz
    Krakowiak, Jan
    Karbownik, Michał
    Podlecka, Daniela
    Hanke, Wojciech
    Polańska, Kinga
    Powiązania:
    https://bibliotekanauki.pl/articles/2161996.pdf
    Data publikacji:
    2019-04-03
    Wydawca:
    Instytut Medycyny Pracy im. prof. dra Jerzego Nofera w Łodzi
    Tematy:
    children
    neurodevelopment
    duration of breastfeeding
    child psychomotor development
    Bayley Scales of Infant and Toddler Development
    1-year-old children
    Opis:
    Objectives The objective of this study was to evaluate the association between breastfeeding duration and child neurodevelopment based on the Polish Mother and Child Cohort Study. Material and Methods The current analysis included 501 mother–child pairs. The analysis evaluating the association between the length of breastfeeding and child neurodevelopment considered the following variables: maternal age and body mass index, weight gain during pregnancy, parental level of education, marital status, socioeconomic status, child gender, birthweight, type of delivery, preterm delivery, pre- and postnatal exposure to tobacco constituents and child day care attendance. Psychomotor development was assessed in 1-year-olds on the Bayley Scales of Infant and Toddler Development. Results The length of breastfeeding correlated positively with maternal age at delivery (ρ = 0.13), maternal and paternal level of education (ρ = 0.2 and ρ = 0.14 respectively), birthweight (ρ = 0.1) and marital status (ρ = 0.16) (p < 0.05). A negative correlation between the length of breastfeeding and maternal smoking status during the first year after delivery (ρ = –0.19) and weight gain during pregnancy (r = –0.1) was observed (p < 0.05). The association between the duration of breastfeeding and child development was not statistically significant in the model with the inclusion of confounding variables. A significant association between language development and maternal level of education (p = 0.004), gender of the child (p = 0.0007) and maternal weight gain during pregnancy (p = 0.01) was found. A negative association between cognitive development and maternal salivary cotinine during pregnancy (p = 0.03) and a negative association between motor development and maternal smoking status during the first year after delivery (p = 0.007) were also found. Conclusions This study found no significant association between the duration of breastfeeding and child development after adjustment for confounders. Int J Occup Med Environ Health. 2019;32(2):175–84
    Źródło:
    International Journal of Occupational Medicine and Environmental Health; 2019, 32, 2; 175-184
    1232-1087
    1896-494X
    Pojawia się w:
    International Journal of Occupational Medicine and Environmental Health
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Effects of benzo(a)pyrene exposure on the ATPase activity and calcium concentration in the hippocampus of neonatal rats
    Autorzy:
    Yang, Kai
    Chen, Chengzhi
    Cheng, Shuqun
    Cao, Xianqing
    Tu, Baijie
    Powiązania:
    https://bibliotekanauki.pl/articles/2161850.pdf
    Data publikacji:
    2017-03-30
    Wydawca:
    Instytut Medycyny Pracy im. prof. dra Jerzego Nofera w Łodzi
    Tematy:
    hippocampus
    neurodevelopment
    ATPase activity
    Ca2+ concentration
    neonatal rats
    Benzo(a)pyrene
    Opis:
    Objectives To investigate whether postnatal benzo(a)pyrene (B(a)P) exposure caused the impairments on the process of neurodevelopment and the alteration in the calcium medium in the neonatal rats. Material and Methods Eighty neonatal Sprague Dawley (SD) rats were randomly divided into 5 groups (untreated control group, vehicle group, 0.02 mg/kg, 0.2 mg/kg and 2 mg/kg B(a)P-exposed group). Rats were treated with B(a)P by the intragastric administration from postnatal day (PND) 4 to 25. Morris water maze (MWM) was employed to observe the spatial memory of rats. The activity of calcium adenosine triphosphatase (Ca2+-ATPase), sodium-potassium adenosine triphosphatase (Na+-K+-ATPase) and calcium-magnesium adenosine triphosphatase (Ca2+-Mg2+-ATPase) in the hippocampus were detected by commercial kits. Fura-2 pentakis(acetoxymethyl) (Fura-2/AM) probe and reactive oxygen species (ROS) reagent kit were used for measuring the concentration of Ca2+ and ROS in the hippocampus synapse, respectively. Results Rats exposed to B(a)P resulted in the deficits in the spatial memory manifested by the increased escape latency and decreased number of crossing platform and time spent in target quadrant in comparison with the control groups. Benzo(a)pyrene exposure caused the significant decrease in the ATPase activity in the hippocampus and caused Ca2+ overload in the synaptic, besides, the ROS concentration increased significantly which may further induce neurobehavioral impairment of the neonatal rats. Conclusions Our findings suggest that postnatal B(a)P exposure may cause the neurobehavioral impairments in the neonatal rats, which were mediated by the decreased ATPase activity and elevated Ca2+ concentration. Int J Occup Med Environ Health 2017;30(2):203–211
    Źródło:
    International Journal of Occupational Medicine and Environmental Health; 2017, 30, 2; 203-211
    1232-1087
    1896-494X
    Pojawia się w:
    International Journal of Occupational Medicine and Environmental Health
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Polish Mother and Child Cohort Study (REPRO_PL) – Methodology of the follow-up of the children at the age of 7
    Autorzy:
    Polańska, Kinga
    Hanke, Wojciech
    Król, Anna
    Potocka, Adrianna
    Waszkowska, Małgorzata
    Jacukowicz, Aleksandra
    Gromadzińska, Jolanta
    Wąsowicz, Wojciech
    Jerzyńska, Joanna
    Stelmach, Włodzimierz
    Stelmach, Iwona
    Powiązania:
    https://bibliotekanauki.pl/articles/2168369.pdf
    Data publikacji:
    2016-11-18
    Wydawca:
    Instytut Medycyny Pracy im. prof. dra Jerzego Nofera w Łodzi
    Tematy:
    lifestyle
    exposure
    neurodevelopment
    birth cohort
    follow-up of children
    child’s health
    Opis:
    Effects of environmental exposures in utero and in the first years of life on early life health and development is a growing research area with major public health implications. The main aim of this work has been to provide an overview of the next step of the Polish Mother and Child Cohort Study (REPRO_PL) covering exposure, health and neurodevelopment assessments of children at 7 years of age. Details regarding methodology of the follow-up of the children are crucial for cross-cohort collaboration and a full understanding of the future research questions. Phase III of the REPRO_PL cohort covers a follow-up of 900 children at the age of 7 years old. The questionnaire filled in by the mothers is composed of: socio-demographic, child exposure and home environment information, nutritional status and health data. In the case of 400 children, environmental (including collection of urine, saliva and buccal cells), health status and psychomotor assessments are performed. Health and development check consists of physical measurements, child health status assessment (including lung function tests, skin prick testing, an interview/examination by an allergist) and psychomotor development tests (the Strength and Difficulties Questionnaire and the Intelligence and Development Scales). The results of the study will become available within the next few years. Extension of the REPRO_PL cohort with examinations of children at the age of 7 years old may provide a better understanding of the relationship between environmental and lifestyle-related factors and children’s health and neurodevelopment; and may further strengthen scientific base for policies and interventions promoting healthy lifestyle. Int J Occup Med Environ Health 2016;29(6):883-893
    Źródło:
    International Journal of Occupational Medicine and Environmental Health; 2016, 29, 6; 883-893
    1232-1087
    1896-494X
    Pojawia się w:
    International Journal of Occupational Medicine and Environmental Health
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Bisphenol A – Application, sources of exposure and potential risks in infants, children and pregnant women
    Autorzy:
    Mikołajewska, Karolina
    Stragierowicz, Joanna
    Gromadzińska, Jolanta
    Powiązania:
    https://bibliotekanauki.pl/articles/2177413.pdf
    Data publikacji:
    2015-04-07
    Wydawca:
    Instytut Medycyny Pracy im. prof. dra Jerzego Nofera w Łodzi
    Tematy:
    Bisphenol A
    exposure
    children
    pregnant women
    dietary exposure
    neurodevelopment
    Opis:
    Bisphenol A (BPA) is used in the chemical industry as a monomer in the production of plastics. It belongs to a group of compounds that disturb some of the functions of human body, the endocrine system in particular. Extensive use of BPA in manufacturing products that come in contact with food increases the risk of exposure to this compound, mainly through the digestive tract. Literature data indicate that exposure to bisphenol A even at low doses may result in adverse health effects. The greatest exposure to BPA is estimated among infants, children and pregnant women. The aim of this review is to show potential sources of exposure to bisphenol A and the adverse health effects caused by exposure to this compound in the group of particular risk.
    Źródło:
    International Journal of Occupational Medicine and Environmental Health; 2015, 28, 2; 209-241
    1232-1087
    1896-494X
    Pojawia się w:
    International Journal of Occupational Medicine and Environmental Health
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Smoking and alcohol drinking during pregnancy as the risk factors for poor child neurodevelopment – A review of epidemiological studies
    Autorzy:
    Polańska, Kinga
    Jurewicz, Joanna
    Hanke, Wojciech
    Powiązania:
    https://bibliotekanauki.pl/articles/2177372.pdf
    Data publikacji:
    2015-05-18
    Wydawca:
    Instytut Medycyny Pracy im. prof. dra Jerzego Nofera w Łodzi
    Tematy:
    children
    behavior
    prenatal smoking
    prenatal alcohol
    neurodevelopment
    Opis:
    Maternal active and passive smoking and low or moderate alcohol drinking during pregnancy, taking into account the level of exposure and developmental or behavioral outcomes, are recognized as a significant issue from both a clinical and a public health perspective. The article aims at evaluating the impact of prenatal exposure to tobacco smoke constituents and low or moderate alcohol drinking during pregnancy on children neurodevelopment by reviewing the most recently published literature. Relevant studies were identified by searching the Pubmed, Medline and Ebsco literature databases. This review is restricted to 29 human studies published in English in peer reviewed journals since 2006. The studies published recently continued to show some relationship between tobacco smoke exposure, from active and passive maternal smoking during pregnancy, and children’s psychomotor development independent of other variables, but this relationship is not straightforward. The association is mostly consistent for measures of academic achievements and behavioral problems which require further attention. The results of the studies on low or moderate exposure to alcohol are not fully conclusive, but some of them suggest that consumption of alcohol during pregnancy may adversely affect children’s intelligence quotient (IQ), mental health, memory and verbal or visual performance. As the reviewed studies indicate, maternal lifestyle during pregnancy like alcohol drinking or smoking may affect children neurodevelopment. All effort should be taken to eliminate such exposure to ensure appropriate children’s development.
    Źródło:
    International Journal of Occupational Medicine and Environmental Health; 2015, 28, 3; 419-443
    1232-1087
    1896-494X
    Pojawia się w:
    International Journal of Occupational Medicine and Environmental Health
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Effects of polybrominated diphenyl ethers on thyroid hormone, neurodevelopment and fertility in rodents and humans
    Autorzy:
    Czerska, Marta
    Zieliński, Marek
    Kamińska, Joanna
    Ligocka, Danuta
    Powiązania:
    https://bibliotekanauki.pl/articles/2179114.pdf
    Data publikacji:
    2013-08-01
    Wydawca:
    Instytut Medycyny Pracy im. prof. dra Jerzego Nofera w Łodzi
    Tematy:
    PBDEs
    thyroid hormone
    neurodevelopment
    fertility
    rodents
    humans
    Opis:
    Polybrominated diphenyl ethers (PBDEs) are used as flame retardants. Due to their widespread use in many consumer products, PBDEs can be found in food as well as in the environment. Their presence has also been found in the human serum, human adipose tissue and human breast milk. Results of experimental studies suggest that the presence of PBDE in the environment is not neutral to our health. In rats and mice exposed to PBDE disturbances in thyroid hormone homeostasis and reproductive system such as changes in reproductive organs weight and disorders in sperm motility and motion were found. In rodents, pre- and postnatal exposure to PBDE can cause neurobehavioral effects. Also in humans disturbances in thyroid hormone system, weight of reproductive organs and concentrations of sex hormones associated with PBDEs serum concentrations were found. Exposure to PBDEs during pregnancy may lead to slower mental and psychomotor development in infants. In this paper the results of previous animal a nd human studies are reviewed.
    Źródło:
    International Journal of Occupational Medicine and Environmental Health; 2013, 26, 4; 498-510
    1232-1087
    1896-494X
    Pojawia się w:
    International Journal of Occupational Medicine and Environmental Health
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Polish mother and child cohort study (REPRO_PL) — Methodology of follow-up of the children
    Autorzy:
    Polańska, Kinga
    Hanke, Wojciech
    Jurewicz, Joanna
    Sobala, Wojciech
    Madsen, Christian
    Nafstad, Per
    Magnus, Per
    Powiązania:
    https://bibliotekanauki.pl/articles/2185377.pdf
    Data publikacji:
    2011-12-01
    Wydawca:
    Instytut Medycyny Pracy im. prof. dra Jerzego Nofera w Łodzi
    Tematy:
    birth cohort
    follow-up of children
    child’s health
    neurodevelopment
    Opis:
    Background: A prospective cohort study design gives the opportunity for identifi cation, update of different exposures and their verifi cation by biomarker measurements. The aim of The Polish Mother and Child Cohort Study (REPRO_PL) is to evaluate the impact of exposure to different environmental factors during pregnancy and, after birth, on the pregnancy outcome, children’s health and neurodevelopment. Materials and Methods: REPRO_PL cohort was established in 2007. From the cohort of 1300 mother-child pairs, 300 children are followed-up until they are two years old to asses the exposure, health status and neurodevelopment. Children are examined twice: at one and two years of age by a pediatrician and a psychologist/child development specialist. During each visit, detailed questionnaire is conducted with the mothers and supplemented with the information from the medical charts to have appropriate recognition of the child’s health and development. Additionally, the current health status of the child is checked and his/her biometry is performed. A urine sample is collected from each child for the verifi cation of environmental tobacco smoke (ETS) and polycyclic aromatic hydrocarbons (PAH) exposure. Some children have a blood sample collected for the assessment of the lead and cadmium levels. Child’s neurodevelopment is assessed based on Bayley Scales for Infant and Toddler Development (Bayley-III). Results and Conclusions: The results of the study will become available within the next few years and will help to determine the impact of the environmental exposures on children’s health and neurodevelopment. REPRO_PL cohort is a middle-sized cohort, very much focused on specific research questions with the potential for future extension and cooperation.
    Źródło:
    International Journal of Occupational Medicine and Environmental Health; 2011, 24, 4; 391-398
    1232-1087
    1896-494X
    Pojawia się w:
    International Journal of Occupational Medicine and Environmental Health
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
      Wyświetlanie 1-7 z 7

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