Temat: nerve fibre - Katalog OPAC zbiorów

Skocz do pozycji: 1.

Tytuł:: The influence of botulinum toxin type A (BTX) on the immunohistochemical characteristics of noradrenergic and cholinergic nerve fibres supplying the porcine urinary bladder wall
Autorzy:: Lepiarczyk, E.
Bossowska, A.
Kaleczyc, J.
Majewski, M.
Powiązania:: https://bibliotekanauki.pl/articles/32489.pdf
Data publikacji:: 2011
Wydawca:: Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:: botulinic toxin type A
immunohistochemistry
noradrenergic nerve fibre
cholinergic nerve fibre
nerve fibre
pig
urinary bladder
bladder wall
botulinum toxin
neurotoxin
autonomic neuron
Opis:: Botulinum toxin (BTX) belongs to a family of neurotoxins which strongly influence the function of autonomic neurons supplying the urinary bladder. Accordingly, BTX has been used as an effective drug in experimental therapies of a range of neurogenic bladder disorders. However, there is no detailed information dealing with the influence of BTX on the morphological and chemical properties of nerve fibres supplying the urinary bladder wall. Therefore, the present study investigated, using double-labeling immunohistochemistry, the distribution, relative frequency and chemical coding of cholinergic and noradrenergic nerve fibers supplying the wall of the urinary bladder in normal female pigs (n=6) and in the pigs (n=6) after intravesical BTX injections. In the pigs injected with BTX, the number of adrenergic (DβH-positive) nerve fibers distributed in the bladder wall (urothelium, submucosa and muscle coat) was distinctly higher while the number of cholinergic (VAChT-positive) nerve terminals was lower than that found in the control animals. Moreover, the injections of BTX resulted in some changes dealing with the chemical coding of the adrenergic nerve fibers. In contrast to the normal pigs, in BTX injected animals the number of DβH/NPY- or DβH/CGRP-positive axons was higher in the muscle coat, and some fibres distributed in the urothelium and submucosa expressed immunoreactivity to CGRP. The results obtained suggest that the therapeutic effects of BTX on the urinary bladder might be dependent on changes in the distribution and chemical coding of nerve fibers supplying this organ.
Źródło:: Polish Journal of Veterinary Sciences; 2011, 14, 2
1505-1773
Pojawia się w:: Polish Journal of Veterinary Sciences
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 2.

Tytuł:: Functional studies on sciatic nerve blood flow in respect to its vascular supply and tonic neural activity
Autorzy:: Stolarczyk, A.
Papierski, K.
Adamczyk, G.
Sinski, M.
Sawionek, L.
Przybylski, J.
Powiązania:: https://bibliotekanauki.pl/articles/69564.pdf
Data publikacji:: 2000
Wydawca:: Polskie Towarzystwo Fizjologiczne
Tematy:: blood vessel
nerve fibre
blood flow
peripheral nerve
sciatic nerve
rat
Źródło:: Journal of Physiology and Pharmacology; 2000, 51, 3
0867-5910
Pojawia się w:: Journal of Physiology and Pharmacology
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 3.

Tytuł:: Immunohistochemical characterization of neurons in the vestibular ganglion (Scarpa’s ganglion) of the pig
Autorzy:: Dudek, A.
Sienkiewicz, W.
Kaleczyc, J.
Powiązania:: https://bibliotekanauki.pl/articles/31779.pdf
Data publikacji:: 2012
Wydawca:: Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:: immunohistochemistry
neuron
vestibular ganglion
pig
Scarpa’s ganglion zob.vestibular ganglion
nerve fibre
Opis:: The study was carried out on three 4-month old female pigs. All the animals were deeply anesthetized and transcardially perfused with 4% buffered paraformaldehyde (pH 7.4). Vestibular ganglia (VG) were collected and processed for double-labelling immunofluorescence method. The preparations were examined under the Zeiss LSM 710 confocal microscope equipped with adequate filter blocks. Neurons forming VG were round or oval in shape with a round nucleus in the center. The majority of them (58%) were medium (M) (31-50 μm in diameter) while 28 % and 14% were small (S) (up to 30 μm in diameter) or large (L) (above 50 μm in diameter) in size, respectively. Double-labeling immunofluorescence revealed that VG neurons stained for CGRP (approx. 81%; among them 70.5%, 26.2% and 3.3% were M, S and L in size, respectively), VACHT (57%; 63% M, 24% S, 13% L), Met-Enk (25%; 60% M, 12% S, 28% L), VIP (20%; 88% M, 6% S, L), NPY (15%; 67% M, 20% S, 13% L), GAL (15%; 74% M, 21% S, 5% L), SP (12%; 69% M, 25% S, 6% L) and NOS-positive (12%; 50% S, 50% M). The most abundant populations of intraganglionic nerve fibers were those which stained for CGRP or Met-Enk, whereas only single SP- or NOS-positive nerve terminals were observed.
Źródło:: Polish Journal of Veterinary Sciences; 2012, 15, 3
1505-1773
Pojawia się w:: Polish Journal of Veterinary Sciences
Dostawca treści:: Biblioteka Nauki