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Wyszukujesz frazę "neoplastic cell" wg kryterium: Temat


Wyświetlanie 1-4 z 4
Tytuł:
A clinicopathological study of nasal and paranasal sinus tumours
Autorzy:
Joshi, Ankita
Behera, Subrat
Malik, Junaid
Powiązania:
https://bibliotekanauki.pl/articles/1398946.pdf
Data publikacji:
2021
Wydawca:
Index Copernicus International
Tematy:
histopathology
nasal obstruction
neoplastic lesion
squamous cell carcinom
Opis:
Introduction: A variety of benign and malignant tumours involving the nasal cavity and paranasal sinuses (PNS) are commonly encountered in clinical practice. The presenting features and symptomatology of all sinonasal masses are similar. It is impossible to determine clinically what pathology lies underneath. So a detailed history, clinical examination, proper imaging, and thorough histopathologic evaluation are essential to reach a diagnosis. Objectives The purpose of this study was to classify various types of Benign and malignant lesions presenting as nasal and paranasal mass and characterize their clinico-pathological profile in a tertiary care center. Materials and Methods: This was a prospective study where 120 cases of nasal and paranasal masses were included over a period of 24 months (sep 2013-sep 2015) Clinico-pathological study was carried out in these cases. A provisional diagnosis was made after clinical assessment and radiologic investigations, but final diagnosis was made after histopathologic examination. Results: The number of benign lesions were more than the malignant lesion, 66.66% versus 33.33% respectively. All age groups were involved and the mean age of presentation was benign tumours 29.5 years and malignant tumours 50.25 years. Male to Female ratio was 3:1 for benign tumours and 1.7:1 for malignant tumours. In our study, among benign lesions the occurrence of Angiofibroma was highest seen in 37.5% cases. In malignant lesions, Squamous cell carcinoma was most common seen in 67.5% cases. Carcinoma nasal cavity was the commonest malignant lesion seen in 70% cases. Nasal obstruction was the most common (91.6%) presenting complaint followed by intermittent epistaxis (69.16%) and nasal discharge (58.3%). Conclusion: We concluded that for proper evaluation of a sinonasal mass, clinical, radiologic, and histopathologic evaluation should be carried out conjointly in all the cases. Histopathology always gives a confirmatory diagnosis but in few cases immuno-histocytochemistry becomes the ultimate diagnostic technique for correct and timely intervention.
Źródło:
Polski Przegląd Otorynolaryngologiczny; 2021, 10, 1; 28-35
2084-5308
2300-7338
Pojawia się w:
Polski Przegląd Otorynolaryngologiczny
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Lunasin – a bioactive peptide from triticale (X Triticosecale Wittmack) seeds, inhibits proliferation of cancer HeLa and SK-OV-3 cells
Autorzy:
Galbas, M.E.
Porzucek, F.
Selwet, M.
Nowak, A.
Slomski, R.
Powiązania:
https://bibliotekanauki.pl/articles/80518.pdf
Data publikacji:
2017
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
triticale
Triticosecale
seed
bioactive peptide
lunasin
immunoblotting
proliferation
neoplastic cell
SDS-PAGE electrophoresis
HeLa cell
Źródło:
BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology; 2017, 98, 3
0860-7796
Pojawia się w:
BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Human cytomegalovirus infection as a lifelong health problem
Autorzy:
Figlerowicz, M.
Modlinska-Cwalinska, A.
Mania, A.
Mazur-Melewska, K.
Kemnitz, P.
Jonczyk-Potoczna, K.
Sluzewski, W.
Powiązania:
https://bibliotekanauki.pl/articles/80892.pdf
Data publikacji:
2011
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
human cytomegalovirus
cytomegalovirus
infection
health problem
patient
immune system
peripheral blood cell
atherosclerosis
cardiovascular disease
myocardial ischaemia
myocardial infarction
hypertension
neoplastic transformation
child
Źródło:
BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology; 2011, 92, 4
0860-7796
Pojawia się w:
BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Immunohistochemical study of expression of immunoglobulins in canine B-cell lymphomas
Autorzy:
Sokolowska, J.
Micun, J.
Zabielska, K.
Malicka, E.
Lechowski, R.
Powiązania:
https://bibliotekanauki.pl/articles/31685.pdf
Data publikacji:
2010
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
immunohistochemistry
expression
immunoglobulin
dog
B cell
lymphoma
tumour
neoplastic cell
immunoglobulin light chain
cancer
Opis:
Nineteen canine lymphomas were included in this study. Tumors were classified according to the updated Kiel classification adapted for canine lymphomas by Fournel-Fleury et al. Immunoglobulin light chains (κ and λ) and IgM and IgG expression were determined by immunohistochemical method. In all examined cases neoplastic cells were positive for one of the immunoglobulin light chains. Expression of λ light chains and κ light chains was observed in 18/19 and 1/19 tumors, respectively. In the majority of neoplastic cells in each examined specimen this reaction had a membranous pattern (sκ/sλ). In all examined cases the presence of immunoglobulin light chains was also observed in the cytoplasm of some neoplastic cells (cκ/cλ). These cells were usally rare and never constituted a dominant population. The expression of immunoglobulin was found in 13/19 cases. Most lymphomas were sIgM positive (11/13 cases). In one case expression of IgG was found, and in another lymphoma two populations of neoplastic cells with different expression of examined immunoglobulins (cells with IgM+ and IgG+ phenotypes) were observed. The reaction also had a membranous pattern. The cells containing cytoplasmic immunoglobulins were rare, and in most cases were of the same type as the surface immunoglobulins. Our study has confirmed that canine lymphomas are a monoclonal proliferation of B-cells usually expressing immunoglobulin λ light chains and that the vast majority of tumors deriving from B-cells express IgM. Our study also indicates a possibility of occurence of biclonal lymphomas in canine species.
Źródło:
Polish Journal of Veterinary Sciences; 2010, 13, 4
1505-1773
Pojawia się w:
Polish Journal of Veterinary Sciences
Dostawca treści:
Biblioteka Nauki
Artykuł
    Wyświetlanie 1-4 z 4

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