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Tytuł:
Screening colonoscopy tests in acromegaly patients – authors’ observations
Autorzy:
Malicka, Joanna
Kurowska, Maria
Dudzińska, Marta
Smoleń, Agata
Oszywa-Chabros, Anna
Tarach, Jerzy
Powiązania:
https://bibliotekanauki.pl/articles/552976.pdf
Data publikacji:
2016
Wydawca:
Stowarzyszenie Przyjaciół Medycyny Rodzinnej i Lekarzy Rodzinnych
Tematy:
acromegaly
colonoscopy
colon neoplasm.
Źródło:
Family Medicine & Primary Care Review; 2016, 3; 286-290
1734-3402
Pojawia się w:
Family Medicine & Primary Care Review
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Malignant thymoma – the most common neoplasm in goats
Autorzy:
Szaluś-Jordanow, O.
Czopowicz, M.
Witkowski, L.
Mickiewicz, M.
Moroz, A.
Kaba, J.
Sapierzyński, R.
Bonecka, J.
Jońska, I.
Garncarz, M.
Kwiatkowska, M.
Chutorański, D.
Szołkowska, M.
Frymus, T.
Powiązania:
https://bibliotekanauki.pl/articles/2087485.pdf
Data publikacji:
2019
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
goats
thymus
tumor
neoplasm
Źródło:
Polish Journal of Veterinary Sciences; 2019, 3; 475-480
1505-1773
Pojawia się w:
Polish Journal of Veterinary Sciences
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Pancreatic cysts or pancreatic cystic neoplasms? An analysis of 145 cases
Autorzy:
Wlaźlak, Michał
Oleśna, Aleksandra
Danilewicz, Marian
Strzelczyk, Janusz
Powiązania:
https://bibliotekanauki.pl/articles/1392895.pdf
Data publikacji:
2018
Wydawca:
Index Copernicus International
Tematy:
pancreas
cyst
neoplasm
surgery
cancer
Opis:
Introduction: Detection of the frequency of pancreatic cystic lesions has increased in the recent years. The majority are pseudocysts, the remaining cysts are mainly neoplasms. Proven risk of malignancy affects intraductal papillary mucinous neoplasms (IPMN) and mucinous cystic neoplasms (MCN). The aim of this study was to analyze clinical data of patients with pancreatic cysts or pancreatic cystic neoplasms on operate at Department of General and Transplant Surgery in the Barlicki Hospital in Lodz. Material and methods: In 2007-2016, there were 145 patients operated on at the Department of General and Transplant Surgery in Barlicki Hospital in Lodz, due to pancreatic cystic lesion. The type of operation, histopathological diagnosis and basic demographic data were analyzed. Results: Non-neoplastic cyst (mainly pseudocysts) was found in 66.9% of patients, neoplasms were detected in 33.1%. The mean age was significantly higher in patients with neoplasm than without neoplasm (57.06 years vs. 50.88 years, p=0.009). Neoplastic cyst occurred more frequently in women (68.75% of women, 31.25% of men, p=0.001). Malignant tumor was found in 14.58% of neoplasms cases and in 4.83% of all pancreatic cystic lesions. Conclusions: According to the analyzed material, there is a significant risk of malignancy in patients with pancreatic cyst. Neoplastic cysts are more common in women. Discussion: Pancreatic cystic tumors are treated mainly by resections of pancreas. In case of benign lesions with low risk of malignancy, there are less extensive operations performed, such as enucleations of lesions. There are no guidelines that could be used satisfactorily in follow up of patients with pancreatic cysts.
Źródło:
Polish Journal of Surgery; 2018, 90, 5; 22-26
0032-373X
2299-2847
Pojawia się w:
Polish Journal of Surgery
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Laryngeal tumour of neurogenetic origin – case report and review of the literature
Autorzy:
Majszyk, Daniel
Krawczyk, Przemysław
Kloc, Michał
Rytel, Adam
Osuch-Wójcikiewicz, Ewa
Niemczyk, Kazimierz
Powiązania:
https://bibliotekanauki.pl/articles/1399656.pdf
Data publikacji:
2019
Wydawca:
Index Copernicus International
Tematy:
benign neoplasm
hoarseness
larynx
schwannoma
Opis:
Schwann cell tumours are a rare group of benign neoplasms that origin form peripheral nerves. 0.1%–1.5% develops in the larynx causing hoarseness, difficulty swallowing and dyspnoea. The treatment of choice is surgical resection of the tumour during open type surgery or endoscopic procedure. The chosen surgical technique depends on tumour location, size observed in clinical examination and imaging. Also, clinical manifestation of the disease is included in the decision-making process.
Źródło:
Polski Przegląd Otorynolaryngologiczny; 2019, 8, 3; 35-39
2084-5308
2300-7338
Pojawia się w:
Polski Przegląd Otorynolaryngologiczny
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Diagnosis and therapy of neuroendocrine neoplasms of the gastrointestinal tract
Autorzy:
Deptała, Andrzej
Czerw, Aleksandra
Powiązania:
https://bibliotekanauki.pl/articles/551709.pdf
Data publikacji:
2016
Wydawca:
Stowarzyszenie Przyjaciół Medycyny Rodzinnej i Lekarzy Rodzinnych
Tematy:
neuroendocrine neoplasm
overview
symptoms
diagnosis
treatment.
Źródło:
Family Medicine & Primary Care Review; 2016, 3; 377-381
1734-3402
Pojawia się w:
Family Medicine & Primary Care Review
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Ultrasound Elastography in Clinical Diagnostics and in Scientific Research on Muscles
Autorzy:
Rosicka, Katarzyna
Arlet, Jarosław
Bukowska, Dorota
Mierzejewska-Krzyżowska, Barbara
Powiązania:
https://bibliotekanauki.pl/articles/1030765.pdf
Data publikacji:
2019
Wydawca:
Uniwersytet Szczeciński. Wydawnictwo Naukowe Uniwersytetu Szczecińskiego
Tematy:
diagnostic imaging
neoplasm
skeletal muscles
stiffness
Opis:
Ultrasound elastography is a revolutionary medical imaging technique, enabling a quantitative and qualitative evaluation of tissue stiffness. This paper presents, based on published evidence, a wide range of possibilities for this method in clinical trials and scientific research. The use of dynamic elastography avoids the undesired influence of force applied to the tissue by the elastograph probe on the information content of the obtained image. In clinical practice, elastography is used to identify and examine the pathological condition of soft tissues (including cancer lesions and tendonitis) and to diagnose neuromuscular diseases. It is also used in scientific investigations as a non-invasive method to study the structure of skeletal muscle, including muscle thickness, fiber length and pennation angle using standard ultrasonography mode; it is also possible to obtain information about physical properties such as stiffness. Ultrasound elastography could also be a useful tool for physiotherapists monitoring the rehabilitation process. Based on the results of these studies, advances in elastographic imaging technology, and progress in biomedical diagnostic methods, elastography is expected to become a common method used in clinical diagnostics and scientific research.
Źródło:
Central European Journal of Sport Sciences and Medicine; 2019, 27, 3; 75-82
2300-9705
2353-2807
Pojawia się w:
Central European Journal of Sport Sciences and Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
An uncommon breast lump with the diagnosis of schwannoma
Autorzy:
Shiryazdi, Seyed Mostafa
Safi Dahaj, Farzan
Alamdar Yazdi, Arezoo
Shishehbor, Fatemeh
Powiązania:
https://bibliotekanauki.pl/articles/1391894.pdf
Data publikacji:
2020
Wydawca:
Index Copernicus International
Tematy:
breast
neoplasm
palpable breast mass
schwannoma
Opis:
Introduction: Schwannoma (neurilemmoma) is a kind of a slow-growing, benign, and heterogeneous neoplasm originating from Schwann cells. Schwannoma has a predilection for the head, neck, and extremities. However, it can occur in the breast dermis, deep breast parenchyma, and axillary soft tissue. Case report: In this study, a 51-year-old woman is reported with a breast mass suspected of malignancy, who was diagnosed with schwannoma by a pathologist after surgery. In cases with palpable breast masses, Schwannoma should be considered as a part of differential diagnosis. In spite of various imaging modalities used in the diagnostics of breast lesions, excisional or core needle biopsy is suggested for the definitive diagnosis of schwannoma.
Źródło:
Polish Journal of Surgery; 2020, 92, 5; 60-62
0032-373X
2299-2847
Pojawia się w:
Polish Journal of Surgery
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Lipomas – a health condition that cannot be ignored
Autorzy:
Sitarz, Robert
Skierucha, Małgorzata
Jazienicki, Mieczysław
Kurylcio, Andrzej
Wierzbicki, Ryszard
Maciejewski, Ryszard
Polkowski, Wojciech
Powiązania:
https://bibliotekanauki.pl/articles/552891.pdf
Data publikacji:
2016
Wydawca:
Stowarzyszenie Przyjaciół Medycyny Rodzinnej i Lekarzy Rodzinnych
Tematy:
lipoma
lipomatosis
soft tissue neoplasm
general practice.
Źródło:
Family Medicine & Primary Care Review; 2016, 4; 473-476
1734-3402
Pojawia się w:
Family Medicine & Primary Care Review
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Limitations in cardiovascular fitness and rehabilitation of oncologically treated patients
Ograniczenia wydolności układu krąŜenia a rehabilitacja pacjentów leczonych onkologicznie
Autorzy:
Hojan, Katarzyna
Powiązania:
https://bibliotekanauki.pl/articles/1963092.pdf
Data publikacji:
2012
Wydawca:
Akademia Wychowania Fizycznego im. Bronisława Czecha w Krakowie
Tematy:
neoplasm
cardiotoxicity
Physical activity
cardio-pulmonary fitness
Opis:
Introduction: Applying increasingly modern forms of cancer treatment contributes to the higher survival of patients with neoplasm. Nevertheless, every single element of such a treatment, no matter how effective, brings some risk of cardiovascular complications.Objective: The study objective was a review of the clinical research analyzing cardiovascular complications resulting from various forms of oncological treatment and the use of rehabilitation in these patients.Material: The study presents contemporary forms of cancer treatment which may cause negative cardiovascular symptoms.Results: Due to their negative influence on the cardiovascular system oncological drugs can be divided into those: causing heart muscle mass loss, arrhythmia, with a cardio depressive effect, hypertension, heart ischemia as well as those enhancing thrombo-embolic disorders. The cardiotoxicity of oncological treatment is very frequent in patients after combination therapy (using chemotherapy or/and radiotherapy) or with coexisting heart disease. According to the heart failure classification every patient after chemotherapy or/and radiotherapy has a higher risk of its development. Thus it is important to know the type of treatment, its dosages, the time from initiation to the treatment completion, so that the rehabilitation program for this group of patients based on exercise is applied through correct medically supervised physical activities.Conclusions: The oncological benefit of therapy is much higher than the possible cardiological risk but, keeping the patient’s wellbeing in mind, an optimal cardiac diagnostic is necessary so as rehabilitation is based on individual cardiac fitness. In patients with cancer, special attention should be paid to the assessment of the cardio-respiratory endurance rates before rehabilitation and the choice of physical activity, sporting discipline made for this group of patients.
Wstęp: Zastosowanie co raz nowszych form terapii w leczeniu onkologicznym poprawia skutecznie przeżycie chorych na nowotwory. Nadal jednak każdy element tej terapii, jakkolwiek bardzo skuteczny, niesie ryzyko powikłań ze strony układu krążenia. Cel: Celem badań było przedstawienie przeglądu badań klinicznych oceniających powikłania w układzie sercowo-naczyniowym wynikające z zastosowania różnych form leczenia onkologicznego oraz rehabilitacji w tej grupie pacjentów. Materiał: W pracy przedstawiono współczesne leczenie nowotworów, które może powodować objawy niepożądane z zakresu układu sercowo-naczyniowego. Wyniki: Leki onkologiczne ze względu na negatywny wpływ na układ sercowo-naczyniowy podzielono na: powodujące utratę masy mięśnia sercowego, wywołujące zaburzenia rytmu i przewodzenia, o działaniu kardiodepresyjnym, powodujące nadciśnienie, niedokrwienie mięśnia sercowego oraz sprzyjające incydentom zakrzepowo-zatorowym. Kardiotoksyczność terapii onkologicznej jest szczególnie wyrażona u pacjentów po leczeniu skojarzonym (z zastosowaniem chemioterapii i radioterapii) lub współistniejącą chorobą serca. Zgodnie z klasyfikacją niewydolności serca kaŜdy pacjent po chemioterapii i/lub radioterapii ma zwiększone ryzyko jej rozwoju, dlatego ważna jest znajomość rodzaju stosowanego leczenia onkologicznego, jego dawek, cykli i czasu od rozpoczęcia lub zakończenia leczenia, aby program usprawniania dla tej grupy pacjentów, oparty o zastosowanie wysiłku fizycznego, był realizowany poprzez właściwą aktywność fizyczną i pod kontrolą lekarza. Wnioski: Korzyść onkologiczna terapii jest dużo wyższa niż potencjalne ryzyko kardiologiczne, ale mając na uwadze dobro pacjenta, konieczna jest optymalna diagnostyka kardiologiczna i prowadzenie rehabilitacji w zależności od określonej wydolności krążenia. U chorych leczonych onkologicznie należy ze szczególną uwagą ocenić wydolność krążeniowo-oddechową przed rozpoczęciem rehabilitacji oraz zaproponowaniem aktywności fizycznej (np. dyscypliny sportowej) w tej grupie pacjentów.
Źródło:
Medical Rehabilitation; 2012, 16(1); 19-25
1427-9622
1896-3250
Pojawia się w:
Medical Rehabilitation
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Morbidity, Mortality and Survival after Stomach Resection with or without Splenectomy – The Single Centre Observations
Autorzy:
Stojcev, Zoran
Bobowicz, Maciej
Jarząb, Michał
Pawłowska-Stojcev, Tomasz
Banasiewicz, Tomasz
Powiązania:
https://bibliotekanauki.pl/articles/1396190.pdf
Data publikacji:
2013-08-01
Wydawca:
Index Copernicus International
Tematy:
neoplasm
stomach
splenectomy
complications
lymph node excision
Opis:
Over the last decade, gastric cancer treatment has changed from extensive multiorgan resections towards less invasive approaches with limited resections and a more selective lymphadenectomy. Despite all available trials, the conclusions on the extent of necessary resections still remain debatable. The aim of the study was to assess the short term outcomes (morbidity and mortality) of a total gastrectomy depending on the simultaneous splenectomy status. Material and methods. We performed a retrospective analysis of the records of all patients treated with a curative intent using a total gastrectomy for gastric cancer between 1997 and 2003. 49 patients fulfilled the inclusion criteria. Patients were divided into two groups: S(+) gastrectomy with splenectomy group (29 patients) and S(-) total gastrectomy with spleen preservation (20 patients). Results. Survival analysis at one year showed that there was no difference in survival between the two groups (p=0.84). There were six recurrences, one in the group S(+) and five in group S(-) (p>0.05). Dissemination was observed in three patients in group S(-) (p>0.05). Other complications including infectious complications, exenteration, subileus, cardiovascular insufficiency, multiorgan failure were more frequent in the S(+) group (31% v 15%) although the difference was not significant (p=0.17). Conclusions. Splenectomy during gastrectomy for cancer has no statistically significant impact on short-term morbidity and mortality. Even though it does not show benefit in terms of 5-year overall survival rates it might be performed when needed in more advanced cases in properly selected patients (e.g. upper gastric T3/4 gastric cancer)
Źródło:
Polish Journal of Surgery; 2013, 85, 8; 433-437
0032-373X
2299-2847
Pojawia się w:
Polish Journal of Surgery
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Breast fibroadenomas: a review in the light of current literature
Autorzy:
Salati, Sajad Ahmad
Powiązania:
https://bibliotekanauki.pl/articles/1391523.pdf
Data publikacji:
2021
Wydawca:
Index Copernicus International
Tematy:
adolescence
benign breast neoplasm
breast lump
fibroadenoma
observation
Opis:
Introduction: Fibroadenomas are one of the most common benign tumors of the breast in the adolescent females accounting for about 2/3rd of all the breast lumps and more than half of all the biopsied breast lesions. They come into being due to overgrowth of glandular tissue under the influence of hormonal changes that the girls undergo at the time of puberty. Due to the wide prevalence of fibroadenomas and the psychosocial morbidity associated with the finding of a breast mass, it is imperative for physicians treating adolescent patients to be thoroughly familiar and updated with this disease. Aim: The article aims at providing a brief review of the classification, presentation, diagnosis, and update on the management of breast fibroadenomas on the basis of recent literature.
Źródło:
Polish Journal of Surgery; 2021, 93, 1; 40-48
0032-373X
2299-2847
Pojawia się w:
Polish Journal of Surgery
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Clinical manifestation of malignant lymphomas of the head and neck region
Autorzy:
Bojanowska-Poźniak, Katarzyna
Nurkowska, Monika
Danilewicz, Marian
Pietruszewska, Wioletta
Powiązania:
https://bibliotekanauki.pl/articles/1398500.pdf
Data publikacji:
2017
Wydawca:
Index Copernicus International
Tematy:
malignant lymphoma
head and neck neoplasm
extranodal lymphoma
Opis:
Introduction: Malignant lymphoma (ML) is a neoplasm caused by clonal expansion of undifferentiated B, T and NK-lymphoid cells. WHO classification divides lymphomas into two main types, i.e. Hodgkin lymphoma (HL), and non-Hodgkin lymphoma (NHL), with numerous subtypes. The majority of MLs are localized in lymph nodes, but extranodal locations are also possible. MLs represent approximately 3-5% of all malignant neoplasms in Poland, but their incidence has been increasing in recent years, especially in young patients. The objective of the study was to evaluate clinical manifestations and diagnostic process in patients with malignant lymphomas of the head and neck region as diagnosed in the Department of Otorhinolaryngology of the Medical University of Lodz in years 2013-2017. Material and method: 30 patients diagnosed with malignant lymphomas of the head and neck region at the Departbadament of Otorhinolaryngology of the Medical University of Lodz in 2013-2017. Results: The study group consisted of 8 cases of nodal lymphomas and 22 cases of extranodal lymphomas. In 29 cases B-cell lymphomas were diagnosed. The most common symptoms included lymphadenopathy or neck tumor. Other symptoms were associated with the location of tumors in particular body organs. The diagnosis was based on histopathological examination of biopsy (needle or surgical) samples. Conclusion: Malignant lymphomas should be taken into account during differential diagnosis of the tumor or lymphadenopathy of the neck. The diagnosis is difficult because of the nonspecificity of symptoms and the need for interdisciplinary cooperation of many specialists.
Źródło:
Polish Journal of Otolaryngology; 2017, 71, 6; 14-21
0030-6657
2300-8423
Pojawia się w:
Polish Journal of Otolaryngology
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Patient with disseminated malignant tumor of the pancreas. Application of liposomal irinotecan as a new option of palliative treatment
Autorzy:
Galińska, Bogumiła
Becht, Rafał
Powiązania:
https://bibliotekanauki.pl/articles/2047218.pdf
Data publikacji:
2021-07-12
Wydawca:
Medical Education
Tematy:
liposomal irinotecan
malignant neoplasm of the pancreas
pancreatic cancer
Opis:
In palliative treatment of pancreatic neoplasms, chemotherapy regimens with gemcitabine, nab-paclitaxel, oxaliplatin, irinotecan, 5-fluorouracil or combinations of these drugs are used. The registration of liposomal irinotecan in the treatment of stage IV disease in patients with progression after gemcitabine creates new options for the treatment choice. The described case concerns a relatively young patient in whom the use of liposomal irinotecan in the registration indication turned out to be a safe and well-tolerated treatment.
Źródło:
OncoReview; 2021, 11, 3; 73-76
2450-6125
Pojawia się w:
OncoReview
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Gastrojejunocolic Fistula in a 49 Year-Old Male
Autorzy:
Tejedor, Patricia
García-Oria, Miguel
Bodega, Ignacio
Peraza, Jesús
Baquedano, Jesús
Serrano, Ángel
Olmeda, Joaquín
Powiązania:
https://bibliotekanauki.pl/articles/1396623.pdf
Data publikacji:
2012-02-01
Wydawca:
Index Copernicus International
Tematy:
gastrojejunocolic fistula
gastrocolic fistula
colon carcinoma
colon neoplasm
fistula
Opis:
Gastrojejunocolic fistula is an unusual finding in patients with colon neoplams because long evolution time is required for its appearance. The methods of diagnosis have been and continue under discussion, being the barium enema the most accepted nowadays.Gastrocolic fistula is characterized by a declining incidence due to the new methods of diagnosis. An early detection of the tumour is completely necessary to prevent complications like fistulas or malnutrition.We present a case report of gastrojejunocolic fistula in a 49 year-old patient with colon carcinoma.
Źródło:
Polish Journal of Surgery; 2012, 84, 3; 163-166
0032-373X
2299-2847
Pojawia się w:
Polish Journal of Surgery
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Association between clinical stage of oral cancer and expression of immunohistochemical markers
Autorzy:
Świątkowski, Wojciech
Rahnama, Mansur
Tomaszewski, Tomasz
Bigas, Mariola
Świątkowska, Agnieszka
Łobacz, Michał
Wallner, Jan
Powiązania:
https://bibliotekanauki.pl/articles/1393147.pdf
Data publikacji:
2017
Wydawca:
Index Copernicus International
Tematy:
oral cancer
neoplasm markers
squamous cell carcinoma
proliferation markers
Opis:
Aim: The aim of this study is to demonstrate the possible correlation between the expression of examined protein markers - p53, EGFR, PCNA, p44/42 in the mass of the tumor and the clinical stage of disease. Material: 48 patients of the Department and Clinic of Oral and Maxillofacial Surgery, Lublin diagnosed with oral cancer. The control group consisted of 10 patients diagnosed with leukoplakia lesions in the oral cavity. The methods: Immunohistochemical analysis using the detection system DAKO K5007 Cat - Dako REAL ™ Detection System, Peroxidase DAB +, Rabbit / Mouse. Results: Based upon the statistical results, significant correlation between p53 protein and tumor staging; however, a correlation between the level of expression of EGFR, p44/42, PCNA and staging was not likewise revealed. Conclusions: Looking for oral squamous cell carcinoma markers remains an actual issue. Identification of specific markers of oral cancer could be used in screening the population, determining prognosis and response to treatment.
Źródło:
Polish Journal of Surgery; 2017, 89, 6; 17-22
0032-373X
2299-2847
Pojawia się w:
Polish Journal of Surgery
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
The current state of knowledge on small cell and non-small cell lung cancer and the position of durvalumab immunotherapy in lung cancer treatment
Autorzy:
Poboży, Kamil
Domańska, Julia
Domański, Paweł
Powiązania:
https://bibliotekanauki.pl/articles/3200762.pdf
Data publikacji:
2023-01-24
Wydawca:
Medical Education
Tematy:
PD-L1
immunotherapy
durvalumab
neoplasm
oncology
SCLC
NSCLC
Opis:
Lung cancer is the second most frequently diagnosed cancer and the leading cause of cancer-related deaths in the world. These statistics make lung cancer one of the most important targets for modern medicine. The identification of multiple risk factors, including tobacco smoking, has been fundamental in understanding the disease. Late-stage detection is a significant contributor to the high mortality rate of lung cancer. Nonetheless, the role of screening is still debatable. The selection of therapy is primarily based on distinguishing between small-cell and non-small cell lung cancer. Despite the major differences in treatment, in both types in specific situations the treatment involves durvalumab – a monoclonal antibody targeting the programmed cell death ligand 1 molecule, which is often present on tumor cells and protects them against the patient’s immune system. The efficacy of durvalumab has been demonstrated in two randomized, multicenter clinical trials. The aim of this study is to summarize the current state of knowledge about lung cancer and durvalumab. Despite the current 5-year survival rate of 19% in lung cancer, the development of immunotherapeutics such as durvalumab may be the key to improving the unfavorable prognosis of lung cancer in the future.
Źródło:
OncoReview; 2022, 12, 4; 75-82
2450-6125
Pojawia się w:
OncoReview
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Incidentally diagnosed epithelioid trophoblastic tumor immediately after delivery: a case report
Przypadkowe rozpoznanie nowotworu nabłonkowatokomórkowego trofoblastu bezpośrednio po porodzie – opis przypadku
Autorzy:
Kwon, Hyun Young
Park, Jung-Woo
Powiązania:
https://bibliotekanauki.pl/articles/1030115.pdf
Data publikacji:
2016
Wydawca:
Medical Communications
Tematy:
epithelioid trophoblastic tumor
gestational trophoblastic disease
rare tumor
uterine neoplasm
Opis:
Epithelioid trophoblastic tumor is a rare malignant lesion of gestational trophoblastic disease, and constitutes an abnormal proliferation of placental trophoblasts. Patients with epithelioid trophoblastic tumor are usually of reproductive age, and have had previous gestations including full-term deliveries, molar pregnancies and abortions. The interval between antecedent gestational events and the diagnosis of epithelioid trophoblastic tumor usually ranges from 0 to 264 months (mean, 84 months). Herein, we report a 42-year-old Korean woman (gravida 2, para 2). At 38 weeks of gestation, she underwent a repeat cesarean section and then hysterectomy due to uterine atony. She was incidentally diagnosed with epithelioid trophoblastic tumor, and postoperatively no metastatic disease was observed. The patient presented no clinical evidence of tumor recurrence for 5 years after surgery. This case is remarkable because epithelioid trophoblastic tumor is a rare disease, and the diagnosis of epithelioid trophoblastic tumor followed immediately after delivery.
Nowotwór nabłonkowatokomórkowy trofoblastu (epithelioid trophoblastic tumor) to rzadka złośliwa postać ciążowej choroby trofoblastycznej. Charakteryzuje się nieprawidłowym rozrostem komórek trofoblastu. Zmiany tego typu rozpoznaje się u kobiet w wieku rozrodczym z ciążą w wywiadzie, zarówno donoszoną, jak i przedwcześnie zakończoną, również z zaśniadem groniastym. Czas między ciążą a rozpoznaniem nowotworu nabłonkowatokomórkowego trofoblastu wynosi od 0 do 264 miesięcy (średnio 84 miesiące). Przedstawiamy przypadek 42-letniej pacjentki z Korei (gravida 2, para 2), u której w 38. tygodniu ciąży wykonano cięcie cesarskie, a następnie histerektomię ze względu na atonię macicy. Przypadkowo rozpoznano nowotwór nabłonkowatokomórkowy trofoblastu, a po zabiegu nie zaobserwowano przerzutów. Pacjentka nie wykazywała cech nawrotu przez 5 lat po zabiegu. Prezentowany przypadek jest szczególny, ponieważ nowotwór nabłonkowatokomórkowy trofoblastu to rzadkość, a rozpoznano go bezpośrednio po porodzie.
Źródło:
Current Gynecologic Oncology; 2016, 14, 3; 174-177
2451-0750
Pojawia się w:
Current Gynecologic Oncology
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Komunikacja pomiędzy lekarzem i pacjentem u chorych na nowotwory
Autorzy:
Wyszkowska, Zofia
Białczyk, Katarzyna
Michalski, Tomasz
Powiązania:
https://bibliotekanauki.pl/articles/1913322.pdf
Data publikacji:
2021-03-31
Wydawca:
Uniwersytet Rzeszowski. Wydawnictwo Uniwersytetu Rzeszowskiego
Tematy:
komunikacja
lekarz
pacjent
choroby nowotworowe
communication
physician
patient
neoplasm disease
Opis:
Celem głównym pracy była ocena komunikacji lekarza z pacjentem. Cele szczegółowe dotyczyły oceny zadowolenia i satysfakcji ze sposobu komunikowania się lekarza z chorym, oceny stosowanych sposobów komunikacji, długości trwania wizyty u lekarza, zrozumiałości przekazywanych informacji chorym, kultury osobistej lekarza, podmiotowości pacjenta. Korzystano z kwestionariusza ankiety opracowanego specjalnie dla zrealizowania celów pracy. W analizie uwzględniono 238 poprawnie wypełnionych kwestionariuszy przez pacjentów z chorobą nowotworową leczonych w szpitalu specjalistycznym. Bazę danych założono w programie Excel, a obliczenia wykonano w programie Statistica. Zebrane dane i ich analiza pokazały, że komunikacja lekarza z chorym jest bardzo ważnym aspektem procesu leczenia. Nie wszyscy respondenci są zadowoleni ze sposobu przekazywania informacji przez lekarza dotyczących dalszego procesu leczenia, co powoduje wzrost poczucia utraty bezpieczeństwa i utratę zaufania do lekarza. Większość chorych rozumie przekazywane przez lekarza zalecenia i porady, ale jest grupa respondentów, która nie rozumie wszystkich słów wypowiadanych przez lekarza, co może prowadzić do nieprawidłowego stosowania zaleceń. Pacjenci wysoko ocenili kulturę osobistą lekarzy, ale oczekują w ich traktowaniu większej podmiotowości. Analiza zebranych wypowiedzi wskazuje, że oczekiwania pacjentów w zakresie prowadzonej komunikacji lekarz – pacjent wzrastają, co zobowiązuje lekarzy do poszerzania wiedzy z zakresu technik komunikacyjnych.
The main goal of the study was to assess the doctor’s communication with the patient. The detailed goals concerned the assessment of satisfaction with the way the physician communicates with the patient, the assessment of the communication methods used, the duration of the visit to a physician’s office, understanding of the information provided to patients, the physician’s personal culture, and the subjectivity of the patient. A questionnaire developed specifically for the study objectives was used. The analysis used data from 238 questionnaires completed correctly by cancer patients treated in a specialist hospital. The database was created in Excel and the analysis was performed using Statistica software. The analysis of the data shows that the physician’s communication with the patient is a very important aspect in the treatment process. Not all respondents were satisfied with the way the physician communicated information about the further treatment process, which increased the sense of security loss and undermined confidence in the physician’s decisions. Most patients understood the recommendations and advice provided by the physician, but there was a group of respondents who did not understand all the words used by the physician, which may lead to the non-compliance of the patient to the treatment recommendations. Patients highly appreciated the personal culture of physicians but they expected greater subjectivity in their treatment. The analysis of statements indicated that the patients’ expectations in the area of physician – patient communication are growing, which obliges physicians to broaden their knowledge in communication techniques.
Źródło:
Nierówności Społeczne a Wzrost Gospodarczy; 2021, 65; 156-168
1898-5084
2658-0780
Pojawia się w:
Nierówności Społeczne a Wzrost Gospodarczy
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
D-dimery w chemioterapii pierwszego rzutu w raku jajnika
Significance of D-dimers in first-line chemotherapy of ovarian cancer
Autorzy:
Stanisławiak, Joanna
Markowska, Janina
Mądry, Radosław
Powiązania:
https://bibliotekanauki.pl/articles/908506.pdf
Data publikacji:
2009
Wydawca:
Medical Communications
Tematy:
D-dimers
neoplasm
ovarian cancer
rirst-line chemotherapy
thromboembolic complications
Opis:
Background: Ovarian cancer is usually diagnosed late and is one of leading causes of genital malignan-cies-related mortality in women. Thromboembolic events are a frequent complication of neoplastic disease, occurring four-fold more often in patients with this disease and six-fold more often in persons undergoing chemotherapy. The aim of paper was to answer the following questions: What is the impact of first-line chemotherapy on D-dimer level during treatment? Is there any correlation between D-dimer level and FIGO stage of ovarian cancer? Is there a correlation between D-dimer level during chemotherapy and completeness of tumour resection? Is there a correlation between D-dimer level and incidence of thromboembolic complications during chemotherapy of ovarian cancer? Material and method: Study population initially consisted of 20 women with ovarian cancer treated at the Department of Oncologic Gynaecology of the K. Marcinkowski Medical University in Poznan. Each patient underwent cytoreductive surgery with subsequent paclitaxel-plati-num chemotherapy. Peripheral blood has been obtained four times from each patient in order to assess D-dimer level, CA 125 tumour marker and blood count. Results: In persons with ovarian cancer, preoperative D-dimer level several-fold exceeded normal range. Application of chemotherapy significantly (p<0.05) reduced D-dimer level in women with ovarian cancer. Conclusions: Assessment of risk of thromboembolic complications in women with ovarian cancer during chemotherapy based on D-dimer level is not possible.
Rak jajnika jest nowotworem późno diagnozowanym i jedną z głównych przyczyn zgonów z powodu nowotworów złośliwych narządu rodnego kobiet. Incydenty zakrzepowo-zatorowe są częstym powikłaniem choroby nowotworowej, występują cztery razy częściej u pacjentów z tą chorobą i sześć razy częściej u osób leczonych chemioterapią. Cel badania: Celem badania była próba odpowiedzi na pytania: Jak chemioterapia pierwszego rzutu wpływa na stężenie D-dimerów podczas leczenia? Czy istnieje związek pomiędzy: stężeniem D-dimerów a stopniem zaawansowania raka jajnika według FIGO; stężeniem D-dimerów podczas chemioterapii a radykalnością zabiegu operacyjnego; stężeniem D-dimerów a występowaniem zaburzeń zakrzepowo-zatorowych podczas chemioterapii w raku jajnika? Materiały i metody: Grupę badaną początkowo stanowiło 20 kobiet z rozpoznanym rakiem jajnika hospitalizowanych na Oddziale Ginekologii Onkologicznej Uniwersytetu Medycznego im. K. Marcinkowskiego w Poznaniu. Każda pacjentka została poddana operacji cytoredukcyjnej z następową chemioterapią według schematu paklitaksel i pochodna platyny. Każdej pacjentce czterokrotnie pobrano krew obwodową na oznaczenie stężenia D-dimerów, markera CA 125 oraz morfologii. Wyniki: Stężenie D-dimerów u osób z rakiem jajnika przed zabiegiem operacyjnym kilkakrotnie przewyższało wartości prawidłowe. Stosowanie chemioterapii znamiennie statystycznie (p<0,05) wpływa na obniżenie stężenia D-dimerów u kobiet z rakiem jajnika. Wnioski: Ocena ryzyka wystąpienia zaburzeń zakrzepowo-zatorowych u kobiet z rakiem jajnika podczas chemioterapii na podstawie stężenia D-dimerów nie jest możliwa.
Źródło:
Ginekologia Onkologiczna; 2009, 7, 2; 114-122
1731-5379
Pojawia się w:
Ginekologia Onkologiczna
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Management of Giant Hepatic Hemangioma in Atypical Localization; Report of a Case and Literature Review
Autorzy:
Stankiewicz, Rafał
Kobryń, Konrad
Patkowski, Waldemar
Krawczyk, Marek
Powiązania:
https://bibliotekanauki.pl/articles/1395563.pdf
Data publikacji:
2015-03-01
Wydawca:
Index Copernicus International
Tematy:
giant hemangioma
liver benign neoplasm
cholecystectomy
tumor enucleation
liver surgery
Opis:
Hemangiomas are the most common benign primary hepatic neoplasms, often being incidentally discovered. In most of the cases they are small and asymptomatic. It is widely accepted that clinical intervention is indicated only for symptomatic hemangiomas. We present a case of an asymptomatic giant hemangioma managed by enucleation due to its atypical localization. The hemangioma, originally located in segment 5, was now described in Computer Tomography (CT) Imaging as separating the gallbladder from the liver parenchyma. A careful evaluation of images revealed proximity to the portal vein (PV), right hepatic artery (RHA), right hepatic duct (RHD) and right branch of the portal vein (RBPV). Thus, in the case of an emergent operation, surgical maneuvers in the area of the altered hepatic anatomy and proximity to the hemangioma itself, would in fact increase the risk endangering the patient’s life. After patient’s consent, a surgical enucleation en block with the gall-bladder was performed. It is of great importance that specifically selected, asymptomatic patients diagnosed with a giant hemangioma, with the above mentioned or similar localization should be considered for surgical treatment.
Źródło:
Polish Journal of Surgery; 2015, 87, 3; 139-142
0032-373X
2299-2847
Pojawia się w:
Polish Journal of Surgery
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Submandibular salivary gland tumors: a clinicopathologic review of 58 cases
Autorzy:
Oleśna, Aleksandra
Kubiak, Marcin Jarosław
Kaczmarczyk, Dariusz
Morawiec-Sztandera, Alina
Powiązania:
https://bibliotekanauki.pl/articles/1399736.pdf
Data publikacji:
2018
Wydawca:
Index Copernicus International
Tematy:
Fine-needle aspiration cytology
Salivary gland neoplasm
Salivary gland cancer
Opis:
Objectives: Salivary gland tumors account for only 3% of head and neck tumors. Their character is mostly benign, although tumors of the submandibular gland are more often malignant. The purpose of this article was to evaluate the structure of patients operated due to submandibular gland tumor and to study the correlation between fine-needle aspiration cytology and postoperative histopathological examination. Methodology: We retrospectively analyzed the medical records of all patients with submandibular gland tumors. The collected data included the demographic structure, results of preoperative fine-needle aspiration cytology and postoperative histopathologic examination. Results: We analyzed 58 patients – 35 women and 23 men with a mean age of 56.6 years. The character of the lesion was benign in 45 cases and malignant in 13. The most frequent benign tumors were pleomorphic adenoma, inflammatory tumor and Warthin’s tumor, whereas most common malignancies were carcinoma planoepitheliale and lymphoma . There were four recurrences. Moreover, we compared results of preoperative fine-needle aspiration cytology and histopathological findings. The accuracy of this examination was almost 83%; 56% of incorrect results involved nondetection of malignancies. The sensitivity and specificity in the diagnosis of those tumors were 58.3% and 97.5%, respectively. Conclusions: The most common types of submandibular gland tumors are pleomorphic adenoma and carcinoma planoepitheliale and lymphoma amongst malignancies. Fine-needle aspiration cytology is accurate in the preoperative diagnosis, mistakes are mostly caused by underdiagnosis of malignant tumors.
Źródło:
Polski Przegląd Otorynolaryngologiczny; 2018, 7, 1; 31-35
2084-5308
2300-7338
Pojawia się w:
Polski Przegląd Otorynolaryngologiczny
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Patient with metastatic breast cancer presenting as acute cholecystitis with one-year survival on hormonotherapy
Autorzy:
Zamkowski, Mateusz
Kąkol, Michał
Makarewicz, Wojciech
Ropel, Jerzy
Bobowicz, Maciej
Powiązania:
https://bibliotekanauki.pl/articles/1392993.pdf
Data publikacji:
2017
Wydawca:
Index Copernicus International
Tematy:
breast neoplasm
advanced cancer
metastatic disease
Acute cholecystitis
gallbladder
laparoscopic cholecystectomy
Opis:
Breast cancer has high metastatic potential with distant metastases involving mainly lungs, liver and bones. Less frequently it gives distant spread to other organs. Herein we would like to present a very rare case of an acute cholecystitis which turned out to be a metastatic breast cancer in previously healthy woman. A female patient, 64-years old, presented to the emergency department with symptoms of biliary colic and acute abdomen. During the emergency cholecystectomy, we diagnosed the gallbladder empyema with thickened wall. There were also multiple metastatic nodules in the peritoneal cavity and an excessive amount of free fluid. The emergency physicians diagnosing female patient with the acute abdominal symptoms and a breast cancer history might suspect malignant spread into abdominal organs including gallbladder. On the other hand, acute cholecystitis symptoms might be the first symptoms of metastatic process in the gallbladder from the unknown primary source, which may be breast.
Źródło:
Polish Journal of Surgery; 2017, 89, 4; 46-49
0032-373X
2299-2847
Pojawia się w:
Polish Journal of Surgery
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Endoscopic ultrasound for differential diagnosis of malignant pancreatic cystic lesions: case report and review of literature
Autorzy:
Janiszewski, Jacek
Woźniak, Joanna
Kot-Gromuł, Iwona
Michalak, Maciej
Kozielec, Zygmunt
Zadrożny, Dariusz
Grabysa, Radosław
Powiązania:
https://bibliotekanauki.pl/articles/1035923.pdf
Data publikacji:
2020-11-05
Wydawca:
Medical Education
Tematy:
endoscopic ultrasound-guided fine-needle aspiration biopsy
mucinous cystic neoplasm
pancreatic cancer
Opis:
A 63-year-old female patient was admitted to the hospital for an in-depth diagnosis of accidentally found pancreatic cystic lesion. The lesion was detected by computed tomography scan and magnetic resonance imaging of the abdomen and identified as potentially malignant mucinous cystic neoplasm (MCN). Endoscopic ultrasound-guided fine-needle aspiration biopsy with the analysis of the fluid from the cyst was performed as well and it confirmed the malignancy of the cystic lesion. The patient was qualified for surgery and the final diagnosis based on histopathological examination of the surgical material confirmed MCN with the accompanying invasive pancreatic adenocarcinoma.
Źródło:
OncoReview; 2020, 10, 3; 103-107
2450-6125
Pojawia się w:
OncoReview
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
58-year-old woman with pancreatic neuroendocrine tumour
Autorzy:
Kolasińska-Ćwikła, Agnieszka
Powiązania:
https://bibliotekanauki.pl/articles/1065803.pdf
Data publikacji:
2014
Wydawca:
Medical Education
Tematy:
GEP-NET/NEN – gastroeneteropancreatic neuroendocrine tumor/neoplasm
chromogranin A
octreotide LAR
somatostatinoma
Opis:
We reported a 58-year-old woman with tumor in the tail and body of pancreas measuring 70 mm in diameter who underwent distal pancreatectomy and splenectomy. Examination of a specimen of the pancreatic mass obtained histopathological features of a well-differentiated neuroendocrine carcinoma (WHO 2000 r. NECLM group 2, MIB < 2%). Immunohistochemical staining showed that the tumor cells were positive for chromogranin and synaptophysin. The tumor was radical resected; there were 9 lymph nodes without metastases. The patient was attending routine follow-up 3 years after resection, when ultrasonography detected hepatic tumor with a low echoic area, confirmed as at least 3 lesions in CT. The patient presented with symptoms of general malaise, anorexia, weight loss, diarrhea, and diabetes mellitus. The diagnosis including of the histopathological features resected specimen and symptoms suggested a somatostatinoma. The patient denied the surgery treatment so she was treated with good clinical and biochemical (normalization of chromogranin A) response to octreotide LAR. During follow-up 4 months after, Computer Tomography showed progression. The patient refused suggested chemotherapy streptozotocin combined with doxorubicin. We continued treatment with octreotide LAR, taking into consideration lack of symptoms and stabilization in chromogranin A level, with good result and stabilization in following Computer Tomography. Somatostatinoma originates from delta cells and is a rare neoplasm, accounting for about 1% of gastroenteropancreatic endocrine neoplasms. About half of somatostatinomas originate in the pancreas, and the remainders originate in other parts of the gastrointestinal tract, mainly in the duodenum. Measurement of the plasma somatostatin concentration is useful for making a diagnosis of somatostatinoma, however is very difficult to perform this examination in our country. Successful treatment with long-acting somatostatin analogues (octreotide LAR) has been reported after progression.
Źródło:
OncoReview; 2014, 4, 2; A76-82
2450-6125
Pojawia się w:
OncoReview
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Hobnail hemangioma of the skin in a juvenile patient
Autorzy:
Ostrowska, A.
Golonka, A.
Bojar, P.
Pasnik, I.
Szumilo, J.
Powiązania:
https://bibliotekanauki.pl/articles/3353.pdf
Data publikacji:
2015
Wydawca:
Instytut Medycyny Wsi
Tematy:
hobnail hemangioma
skin
juvenile
patient
human disease
hobnail cell
vascular malformation
vascular neoplasm
Opis:
Hobnail hemangioma is a rare, benign, vascular lesion with peculiar but commonly misleading morphology, located mostly on the extremities or trunk, and affects young and middle-aged adults with a slightly male predominance. A new typical case in a 17-year-old girl is presented. A single, small, painless skin lesion appeared in an early childhood on the lateral part of the right thigh, and was linked with scratching a previous pigmented lesion. Microscopic examination of the completely removed lesion revealed typical morphology. Prominent endothelial cells were podoplanin-negative and CD34-positive. There was no recurrence after four years follow-up.
Źródło:
Journal of Pre-Clinical and Clinical Research; 2015, 09, 1
1898-2395
Pojawia się w:
Journal of Pre-Clinical and Clinical Research
Dostawca treści:
Biblioteka Nauki
Artykuł
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