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Tytuł:
First-principles study on the adsorption structure of water molecules on a pyrite (100) surface
Autorzy:
Liu, Yingchao
Chen, Jianhua
Li, Yuqiong
Zhang, Junjie
Kang, Duan
Powiązania:
https://bibliotekanauki.pl/articles/1447970.pdf
Data publikacji:
2021
Wydawca:
Politechnika Wrocławska. Oficyna Wydawnicza Politechniki Wrocławskiej
Tematy:
pyrite
water molecules
adsorption
Opis:
The hydration structure of water molecule adsorption at different coverages of a monolayer on a pyrite (100) surface were simulated using the density functional theory (DFT) method. The results demonstrate that the Fe-O interaction weakens and the adsorption energy per water molecule decreases with increasing water coverage, except at a monolayer coverage of 12/12 (i.e., full coverage). H-S and H-O hydrogen bonds were formed on the nearest surface layer. When large amounts of water molecules adsorb onto the surface, the adsorbed water molecules can be divided into three layers: the layer nearest to the surface, the second nearest to the surface, and the layer farthest from the surface. The thickness of the former two layers is approximately 5.5 Å. The three layers have water densities of 1.12 g/cm3, 1.08 g/cm3, and 0.95 g/cm3, respectively, suggesting that there is a strong interaction between the pyrite surface and water molecules and the influence of surface structure on water adsorption reaches a distance of more than 10 Å. Dynamics simulations suggest that the water molecules close to the mineral surfaces are in an orderly arrangement while those far from the surface are disordered.
Źródło:
Physicochemical Problems of Mineral Processing; 2021, 57, 2; 121-130
1643-1049
2084-4735
Pojawia się w:
Physicochemical Problems of Mineral Processing
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Cell adhesion molecules and their possible role in the pathology of the peripheral nerves – a review of the literature
Autorzy:
Niezgoda, Adam
Powiązania:
https://bibliotekanauki.pl/articles/552657.pdf
Data publikacji:
2015
Wydawca:
Stowarzyszenie Przyjaciół Medycyny Rodzinnej i Lekarzy Rodzinnych
Tematy:
cell adhesion molecules
demyelination
polyneuropathies.
Źródło:
Family Medicine & Primary Care Review; 2015, 4; 323-326
1734-3402
Pojawia się w:
Family Medicine & Primary Care Review
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Analitical criteria of homogeneous and heterogeneous detonation of liquid energetic materials
Autorzy:
Kaim, S.
Powiązania:
https://bibliotekanauki.pl/articles/92588.pdf
Data publikacji:
2013
Wydawca:
Sieć Badawcza Łukasiewicz - Instytut Przemysłu Organicznego
Tematy:
mechanism detonation initiation
hot spots
nanopores
emission atoms and molecules
shock dissociation molecules
Opis:
Statistical theory of liquids is used to investigate mechanism of detonation initiation on fronts of flat shock waves in homogeneous liquid and in liquid containing spherical nanopores. We calculated thermodynamic parameters of liquid methane sufficient for shock dissociation of molecules at a front of a shock wave. Calculations of the average single-particle force potential show that at high pressures and temperatures atoms and molecules get emitted from the surface into a nanopore with hyper-thermal speeds. Implosion of spherically symmetric stream of molecules may lead to destruction of the molecules at impact. We explained existence of top and bottom bounds for pressure during detonation initiation in heterogeneous energetic materials. In terms of pair interaction potentials and correlation functions there are formulated criteria for boundary values of thermodynamic parameters which are required for initiation of homogeneous and heterogeneous detonations based on the "hot spot"’ mechanism.
Źródło:
Materiały Wysokoenergetyczne; 2013, T. 5; 5-13
2083-0165
Pojawia się w:
Materiały Wysokoenergetyczne
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Dendrimers: properties and applications.
Autorzy:
Klajnert, Barbara
Bryszewska, Maria
Powiązania:
https://bibliotekanauki.pl/articles/1044187.pdf
Data publikacji:
2001
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
cascade molecules
dendrimers
PAMAM dendrimers
Opis:
Dendrimers are a new class of polymeric materials. They are highly branched, monodisperse macromolecules. The structure of these materials has a great impact on their physical and chemical properties. As a result of their unique behaviour dendrimers are suitable for a wide range of biomedical and industrial applications. The paper gives a concise review of dendrimers' physico-chemical properties and their possible use in various areas of research, technology and treatment.
Źródło:
Acta Biochimica Polonica; 2001, 48, 1; 199-208
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Selected small molecules as inducers of pluripotency
Autorzy:
Baranek, Małgorzata
Markiewicz, Wojciech
Barciszewski, Jan
Powiązania:
https://bibliotekanauki.pl/articles/1038727.pdf
Data publikacji:
2016
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
reprogramming
pluripotency
small molecules
iPSCs
Opis:
The general idea of regenerative medicine is to fix or replace tissues or organs with live and patient-specific implants. Pluripotent stem cells are capable of indefinite self-renewal and differentiation into all cell types of the body. An easily accessible source of induced pluripotent stem cells (iPSCs) may allow obtaining and culturing tissues in vitro. Many approaches in the methods leading to obtain iPSCs have been tested in order to limit immunogenicity and tumorigenesis, and to increase efficiency. One of the approaches causing pluripotency is usage of small molecule compounds. It would be of great importance to assess their specific properties and reveal their new capacity to induce pluripotent stem cells and to improve reprogramming efficiency. Identification of the epigenetic changes during cellular reprogramming will extend our understanding of stem cell biology and many therapeutic applications. In this paper we discuss mainly the nucleotide derivatives, already proven or for now only putative inducers of the cells' pluripotency, that modulate the epigenetic status of the cell.
Źródło:
Acta Biochimica Polonica; 2016, 63, 4; 709-716
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Calcium phosphate nanoparticles for delivering synthetic drug molecules across the cell membrane
Autorzy:
Rotan, O.
Sokolova, V.
Schrader, T.
Epple, M.
Powiązania:
https://bibliotekanauki.pl/articles/285174.pdf
Data publikacji:
2014
Wydawca:
Akademia Górniczo-Hutnicza im. Stanisława Staszica w Krakowie. Polskie Towarzystwo Biominerałów
Tematy:
nanoparticles
cell membranes
drug molecules
Źródło:
Engineering of Biomaterials; 2014, 17, no. 128-129; 77-78
1429-7248
Pojawia się w:
Engineering of Biomaterials
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Na-montmorillonite modified with ammonium salts and azobenzene as a photoactive nanomaterial
Autorzy:
Koteja, A.
Matusik, J.
Powiązania:
https://bibliotekanauki.pl/articles/184535.pdf
Data publikacji:
2016
Wydawca:
Akademia Górniczo-Hutnicza im. Stanisława Staszica w Krakowie. Wydawnictwo AGH
Tematy:
inorganic solid structures
organic molecules
minerals
Opis:
Modification of inorganic solid structures (e.g. minerals) with organic molecules is a constantly developed topic in material sciences. The organic functionalization leads to the production of new materials with integrated properties of both the organic and inorganic component. In the presented study we have modified a Na-montmorillonite with alkylammonium surfactants and subsequently azobenzene, in order to obtain a nanomaterial that shows response to UV radiation. Azobenzene is a photoswitchable organic molecule capable to change its conformation upon UV radiation from the trans- to cis-azobenzene isomer. This reaction is coupled with a change of the molecules shape and dimensions (Klajn 2010). The montmorillonite is a layered aluminosilicate that serves as an excellent host structure for organic guest species. Due to the net negative layer charge it shows the ability to swell and to exchange the originally present interlayer cations. These properties allow the intercalation of bulk organic molecules and to control their arrangement. Much attention has been paid to the possibility of transferring the photoswitching ability of organic molecule into the motion of the whole organo-mineral structure (Heinz et al. 2008). Such nanoswitch is particularly appealing as it is controlled with radiation – remotely and at a precise location. The efficiency of a synthesized nanoswitch depends on an accurate selection of the host and guest component. The target of this study to test a series of organic surfactants and to establish a modification pathway that leads to obtaining a material most promising in the view of its photoresponsive behavior. The montmorillonite modification was performed in a two-step procedure, as the direct intercalation of a nonionic azobenzene is not possible. First, the Na-montmorillonite (denoted SWy) was ion-exchanged with trimethylalkylammonium cations abbreviated C n and benzyldimethylalkylammonium cations – BC n , where n refers to the number of carbon atoms in the alkyl chain and is equal to 12, 14 or 16. In the second step the organo-montmorillonites were reacted with azobenzene (AzBz) for 24 h at 120°C in a hermetically closed teflon vessel. The yellowish products were characterized with the X-Ray diffraction (XRD), the infrared spectroscopy (FTIR) and CHN elemental analysis. In all cases the intercalation of the ammonium cation caused an increase of the montmorillonites basal spacing ( d 001 ). The d 001 values were equal to 16.4 Å, 18.2 Å and 20.5 Å for SWy-C 12 , SWy-C 14 and SWy-C 16 , respectively. The samples modified with the BC n cations showed ~1.5 Å larger basal spacing, due to the presence of the benzyl group in the intercalated molecule. A linear relationship was observed between the d 001 value and the alkyl chain length of the introduced salts. This suggests that the organic cations formed paraffin-type aggregates in the interlayer (Ogawa et al. 1999) where the molecules are inclined to the layer surface. The FTIR spectra of modified SWy sample showed intense bands corresponding to CH 2 vibration modes. Along with the increasing alkyl chain length the CH 2 stretching bands shifted towards lower energies. This is an effect of growing packing density of alkylammonium molecules in the interlayer (He et al. 2004) and it is coupled with straightening of the alkyl chains due to transformation of disordered gauche conformer to the ordered all-trans conformer (Vaia et al. 1994). It can be concluded that the longer alkyl chains (C 16 and BC 16 ) form more ordered, solid-like aggregates in the interlayer space. The molar content of organic molecules was calculated basing on the CHN elemental analysis. The amount of intercalated alkylammonium cations was nearly equal to the cation exchange capacity (CEC) of montmorillonite – 88.9 meq/100 g. The reaction with azobenzene was most effective for montmorillonite modified with the alkylammonium cations having the longest chains as confirmed by the XRD patterns. The d 001 values of SWy-C 16 and SWy-BC 16 samples after reaction with AzBz increased to 36.9 Å and 35.9 Å, respecively. Well resolved and intense (001) peaks as well as the presence of the 2 nd and 3 rd order reflections indicated a highly ordered structure of these intercalates. On the contrary, diffraction peaks were less resolved and broadened for samples prepared with the shorter C 12 , C 14 , BC 12 and BC 14 molecules after reaction with AzBz. Based on these results, it is assumed that the long chain alkylammonium ions are more effective surfactants for the further intercalation of azobenzene into the montmorillonites interlayer space. The obtained highly ordered structures are promising materials for application as photo-actuated nanoswitches.
Źródło:
Geology, Geophysics and Environment; 2016, 42, 1; 87-88
2299-8004
2353-0790
Pojawia się w:
Geology, Geophysics and Environment
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Resonance contributions to low-energy electron collisions with molecular hydrogen
Autorzy:
Horácek, J.
Cížek, M.
Houfek, K.
Kolorenc, P.
Pichl, L.
Powiązania:
https://bibliotekanauki.pl/articles/148461.pdf
Data publikacji:
2003
Wydawca:
Instytut Chemii i Techniki Jądrowej
Tematy:
electron scattering
molecules
attachment
vibrational excitation
Opis:
Calculations of electron dissociative attachment and vibrational excitation of molecular hydrogen by low-energy electrons based on an improved nonlocal resonance model are reported. The role of the rotational excitation of the target molecules is discussed.
Źródło:
Nukleonika; 2003, 48, 2; 109-112
0029-5922
1508-5791
Pojawia się w:
Nukleonika
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Evaluation of neutrophil phagocytic, complement functions, and cytokines expression among diabetic patients in Abuja, Nigeria
Autorzy:
Babandina, Musa Muhammad
Mainasara, Abdullahi Suleiman
Bakare, Mustapha
Emeribe, Anthony Uchenna
Shuwa, Halima Ali
Haruna, Shamsuddeen
Muhammad, Aminu Said
Abdullahi, Idris Nasir
Powiązania:
https://bibliotekanauki.pl/articles/454973.pdf
Data publikacji:
2019
Wydawca:
Uniwersytet Rzeszowski. Wydawnictwo Uniwersytetu Rzeszowskiego
Tematy:
diabetes mellitus
effector molecules
pro-inflammatory markers
Opis:
Introduction. Inflammatory response in Diabetes Mellitus (DM) begins with chronic sub-clinical inflammations as a result of insulin resistance and activation of both innate and adaptive immune system as the disease progresses to complicated diabetes. Hence, the present study investigated the neutrophil phagocytic, complement function (CH50), and some cytokine profiles among diabetic and non-diabetic patients attending the National Hospital in Abuja, Nigeria. Aim. To evaluate the neutrophil phagocytic, complement function (CH50), and some cytokine profiles among post-operative septic diabetic and post-operative septic non-diabetic patients at the National Hospital in Abuja, Nigeria. Material and methods. Subjects were recruited by convenient sampling technique through interviewer-administered questionnaires. Subsequently, blood samples were collected. Fasting blood sugar (FBS) (mmol/L) was determined using glucose oxidase method. Neutrophil function test (Fmol/phag) was assayed using nitroblue tetrazolium reduction test (NBT). Hemolytic complement function (CH 50) test was conducted using serum harvested from sheep sensitized with human group (ORh D +ve) red blood cells. While serum Interleukin-4, -6, -10 and TNF- α were determined using Enzyme Linked Immunosorbent Assay (ELISA). Results. Mean ± Standard deviation (SD) of FBS concentration of 10.5 ± 1.3 (mmol/|L) among diabetic and 4.7 ± 0.9 (mmol/L) among non-diabetics was recorded. There is a decrease in neutrophil phagocytic function with a mean ± SD of 5.4 ± 2.1 (Fmol/ phag) in diabetics compared to 9.2 ± 2.1 (Fmol/phag) in non-diabetics. Similarly, complement (CH 50) function and C-reactive protein were significantly lower in diabetics when compared to non-diabetics (p<0.001). There was a significant difference in IL-6 concentration between diabetics and non-diabetics groups, but no significant difference was observed in TNF-α, IL-4 and IL-10 concentrations between study groups (p>0.05). TNF-α and IL-6 was significantly higher in diabetics with cardiovascular disorders compared to non-diabetics subjects with cardiovascular disorders (p<0.001). Conclusion. Findings from this study revealed the association of complement, neutrophil phagocytic function, CRP and IL-6 among septic diabetic patients,. In addition TNF-α and IL-6 expression was higher in DM patients with cardiovascular disorders.
Źródło:
European Journal of Clinical and Experimental Medicine; 2019, 3; 229-235
2544-2406
2544-1361
Pojawia się w:
European Journal of Clinical and Experimental Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Free electrons: fundamental interactions, applications and data needs
Autorzy:
Christophorou, L.
Powiązania:
https://bibliotekanauki.pl/articles/148509.pdf
Data publikacji:
2003
Wydawca:
Instytut Chemii i Techniki Jądrowej
Tematy:
applications
data
interactions
low-energy electrons
molecules
Opis:
In spite of the important recent advances in the field of low-energy electron interactions with atoms and molecules, there still exist fundamental needs and challenges, some of which are generic in their basic and applied significance. These include measurements of cross sections for a number of fundamental low-energy electron–ground-state molecule interaction processes such as vibrational excitation (direct and indirect) and dissociation into neutral fragments, studies of low-energy electron–excited molecule interactions, investigations of low-energy electron interactions with radicals and transient species, and measurements of electron energy losses in electron–molecule collision processes. They also include studies for linking of knowledge on isolated electron–molecule interactions to that in the condensed phases of matter, and the systematic and quantitative exploration of the interactions of low-energy electrons with molecular and macromolecular biological structures.
Źródło:
Nukleonika; 2003, 48, 2; 67-74
0029-5922
1508-5791
Pojawia się w:
Nukleonika
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Some results of an analysis of polyhydric alcohols effect on detoxication processes
Autorzy:
Konovchuk, V.
Andrushchak, A.
Powiązania:
https://bibliotekanauki.pl/articles/2052425.pdf
Data publikacji:
2015
Wydawca:
Akademia Bialska Nauk Stosowanych im. Jana Pawła II w Białej Podlaskiej
Tematy:
severe sepsis
rheosorbilact
endotoxicosis
medium weight molecules
Opis:
Rheosorbilact action on antitoxic function of the kidneys has been analysed using the values of medium weight molecules in patients with severe sepsis. The study design includes the criteria of inclusion, exclusion and cessation. Patients with pyoceptic complications (mainly surgical abdominal sepsis) with signs of severe endotoxicosis, dopaminergic activity (5-10 mcg/kg min), biochemical criteria of SS (lactate >4 mmole/l, С-reactive protein >2 standard departures from the norm) and other signs of severe sepsis with generalized disorders in homeostasis (assessing the multiple organ damage course by H.Celye-I.A. Yeriuhin scale- 20-27 points, MODS scale – 6-10 points) corresponded to the inclusion criterion. All patients were provided with appropriate debridement and intensive traditional therapy. For control studies we involved patients with systemic inflammatory response syndrome who had 2-3 signs of SIRS in stage A. It was found that rheosorbilact activates the transportation of medium weight molecules out of the extracellular space and increases their excretion by the renal nephrons in patients with severe sepsis. It was established that in severe sepsis rheosorbilact provides a high level of excretion of medium weight molecules by suppressing processes of reabsorption in the proximal nephron portions caused by peptidase dependent metabolism.
Źródło:
Health Problems of Civilization; 2015, 09, 2; 35-38
2353-6942
2354-0265
Pojawia się w:
Health Problems of Civilization
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
The dynamics of biochemical markers of enzymoemia and middle-weight molecules in the early post-traumatic period of brain injury
Autorzy:
Ziablitsev, S. V.
Elskyy, V. N.
Pischulina, S. V.
Strelchenko, U. I.
Antonov, E. V.
Sudilovskaya, U. L.
Khudoley, S. A.
Powiązania:
https://bibliotekanauki.pl/articles/1032378.pdf
Data publikacji:
2014
Wydawca:
Uniwersytet Kazimierza Wielkiego w Bydgoszczy
Tematy:
brain injury
biochemical markers
enzymoemia
middle-weight molecules
Opis:
In the experimental model of brain injury (BI) markers of enzymoemia (aminotransferases ALT and AST, alkaline and acid phosphatase (AlP and AcP), cathepsin D (CD)) and middle-weight molecules (MWM) were estimated. 3 hours after trauma there were increase of all enzymes that evidences about damage of cytoplasmic (ALT, AST, AlF) and lysosomal membranes (AcP, CD). During period of observation different dynamics of enzymatic changes occurred: plateau phase for ALT and CD and progressive increase of concentration with the maximum on the 5th day of the experiment for AlP and AcP. Increase of the level of MWM displayed the development of endogenous intoxication in the post-traumatic period. Relation between particular components of MWM was studied. It was shown that primary accumulation of nucleotide fraction and aromatic peptides is adverse factor of the course of post-traumatic period, development of endotoxicosis, and multiorgan failure.
Źródło:
Journal of Health Sciences; 2014, 4, 1; 297-302
1429-9623
Pojawia się w:
Journal of Health Sciences
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Genetic Variations of the CTNNA1 And The CTNNB1 Genes in Sporadic Colorectal Cancer in Polish Population
Autorzy:
Sygut, Andrzej
Przybyłowska, Karolina
Ferenc, Tomasz
Dziki, Łukasz
Spychalski, Michał
Mik, Michał
Dziki, Adam
Powiązania:
https://bibliotekanauki.pl/articles/1396892.pdf
Data publikacji:
2012-12-01
Wydawca:
Index Copernicus International
Tematy:
sporadic colorectal cancer
muations
catenin gene
adhesion molecules
Opis:
Experimental as well as clinical observations have demonstrated that the E-cadherin/catenin complex is a powerful inhibitor of invasion. Abrogation of this pathway is implicated in the carcinogenesis of several malignancies, especially colorectal cancer. The aim of the study was to determine the CTNNA1 and the CTNNB1 mutations and its relationship to clinical and pathological features of sporadic colorectal cancer (CRC) in Polish patients. Material and methods. Paired tumor and normal tissue samples from 110 sporadic CRC patients undergoing resective surgery were prospectively studied for the alpha catenin (CTNNA1) gene and beta catenin (CTNNB1)gene mutations by PCR/single strand conformation polymorphism (SSCP). Results. The CTNNA1 gene alteration in exon 7 were detected in 4 samples and in exon 3 of CTNNB1 gene were found in 3 samples. There was a trend at the limit of statistical significance associating younger age at diagnosis (<50) with CTNNA1 and the CTNNB1 mutations. The mutation of CTNNB1 seemed to occur more frequently in the proximal colon than distal. The CRC patients with CTNNA1 mutation had a significantly increased lymph node metastasis. On the other hand, there was no correlation between mutations and the other clinical variables (e.g. sex, grade and depth of invasion). Conclusion. Although we found a low frequency of mutations in the CTNNA1 and the CTNNB1 genes, but the analysis the relationship with clinical and pathological features of CRC patients may indicated an association of these mutations with the risk and progression of CRC.
Źródło:
Polish Journal of Surgery; 2012, 84, 11; 560-564
0032-373X
2299-2847
Pojawia się w:
Polish Journal of Surgery
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Cloning and purification of functionally active Fas ligand interfering protein (FIP) expressed in Escherichia coli
Autorzy:
Wisniewski, Pawel
Master, Adam
Kaminska, Bozena
Powiązania:
https://bibliotekanauki.pl/articles/1040813.pdf
Data publikacji:
2008
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
Fas ligand
interfering molecules
recombinant protein purification
Fas
apoptosis
Opis:
This report presents purification and characterization of the extracellular domain of rat Fas protein, called FIP (FasL interfering protein), expressed as inclusion bodies in Escherichia coli. FIP was extracted from the inclusion bodies, solubilized with 8 M urea, purified by a single-step immobilized metal ion (Ni2+) affinity chromatography and refolded. SDS/PAGE and mass spectrometry analysis of the purified protein verified its purity. Fluorescence spectrum analysis showed that the refolding procedure caused structural changes which presumably might have led to oligomerization. The purified FIP has biological activities: it binds specifically soluble Fas ligand and protects human Jurkat lymphocytes against FasL-dependent apoptosis. This efficient procedure of FIP expression in E. coli and renaturation may be useful for production of therapeutically important proteins.
Źródło:
Acta Biochimica Polonica; 2008, 55, 1; 51-56
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Regulatory function of parasites in autoimmune disease – outcome from experimental model infection
Autorzy:
Krawczak, Katarzyna
Donskow-Łysoniewska, Katarzyna
Doligalska, Maria
Powiązania:
https://bibliotekanauki.pl/articles/972241.pdf
Data publikacji:
2017
Wydawca:
Polskie Towarzystwo Parazytologiczne
Tematy:
immunoparasitology
animal model
helminth
autoimmune disorders
parasite driven molecules
Opis:
It is estimated that more than half of the nowadays known species are pathogenic parasites. Among macroparasites gastrointestinal nematodes are one of most common and having significant impact on life and health. Those organisms reveal strong, specific immune response in host, involving primary mechanisms associated with regulatory and Th2 cells. Referring to immunomodulatory abilities of helminths, parasite infections started to be considered as a possible therapy for many autoimmune diseases. Clinical trials on 2nd and 3rd stage are conducted in spite that treatment has not been recognized as safe for common use. Despite that the safety of treatment with parasites is still controversial and widely discussed. Our knowledge about mechanisms used by helminth to moderate immune response is still inadequate to predict possible effect of long lasting parasite infection on individual patients.
Źródło:
Annals of Parasitology; 2017, 63, 1; 7-14
0043-5163
Pojawia się w:
Annals of Parasitology
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Analytical solutions of Schrödinger equation with new solvable potential family V(r)=A/r^2-B/r+Cr^(δ+1) via Nikiforov-Uvarov (NU) method
Autorzy:
Antia, Akaninyene Daniel
Akpan, Ita Okon
Ikot, Akpan Ndem
Maghsoodi, Elham
Zarrinkamar, Saber
Hassanabadi, Hassan
Powiązania:
https://bibliotekanauki.pl/articles/763317.pdf
Data publikacji:
2015
Wydawca:
Uniwersytet Marii Curie-Skłodowskiej. Wydawnictwo Uniwersytetu Marii Curie-Skłodowskiej
Tematy:
Schrödinger equation
Energy eigenvalue
Eigenfunction
Diatomic molecules
Hellmann-Feynmann theorem
Opis:
In this paper, we have presented the exact solutions of the Schrödinger equation with the family of potentials V(r)=A/r^2-B/r+Cr^(δ+1). We have obtained the energy eigenvalues and the corresponding wave functions expressed in terms of the associated Laguerre polynomials for  using the Nikiforov-Uvarov (NU) method. The energy levels for each case is computed for diatomic molecules H2, CO, NO and N2  for various values of and . We have also computed the expectation values of, and the Virial theorem using the Hellmann-Feynmann theorem (HFT).
Źródło:
Annales Universitatis Mariae Curie-Skłodowska, sectio AAA – Physica; 2015, 70
0137-6861
Pojawia się w:
Annales Universitatis Mariae Curie-Skłodowska, sectio AAA – Physica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Markers of endothelial dysfunction in young non-overweight women - effect of serum lipids, body measures and nutrition
Autorzy:
Witkowska, AM.
Zujko, ME.
Powiązania:
https://bibliotekanauki.pl/articles/1916451.pdf
Data publikacji:
2014
Wydawca:
Uniwersytet Medyczny w Białymstoku
Tematy:
endothelial dysfunction
cellular adhesion molecules
lipids
nutrition
body measures,
women
Opis:
Purpose: Since endothelial dysfunction can develop early in the adulthood, the purpose of the study was to determine how serum lipids, body measures and dietary habits affect serum markers of vascular activation in young women. Materials and methods: Twenty five healthy women, aged 19-22 years, were enrolled in the study. Serum lipids profile (total cholesterol, HDL-cholesterol, triglycerides) was assayed with laboratory test kits. Concentrations of sICAM-1, sVCAM-1 and E-selectin were determined with the ELISA technique. Anthropometric measurements were taken including skinfold thickness and waist circumference. Food consumption data were collected using 3 repeats of 24-hour dietary recalls. Dietary habits of the women were assessed with a 9-point alternate Mediterranean Diet score (a-MED). Results: Sixty eight percent of the subjects had their HDL-cholesterol levels below the desirable concentration, 20% had LDL-cholesterol elevated, and 32% demonstrated increased total triacylglycerols (TAG). The levels of serum TAG >199 mg/dL were associated with a significant rise in the VCAM-1 concentration. Dietary wholegrain products seem to reduce the serum E-selectin. Conclusions: The results suggest that young women of normal body mass, but demonstrating increased levels of serum TAG, may be at risk of developing endothelial dysfunction. An implementation of the wholegrain products consumption into their dietary practices would possibly be of health benefit.
Źródło:
Progress in Health Sciences; 2014, 4, 1; 24-30
2083-1617
Pojawia się w:
Progress in Health Sciences
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
The role of cell adhesion molecule in cancer progression and its application in cancer therapy.
Autorzy:
Okegawa, Takatsugu
Pong, Rey-Chen
Li, Yingming
Hsieh, Jer-Tsong
Powiązania:
https://bibliotekanauki.pl/articles/1043281.pdf
Data publikacji:
2004
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
cancer gene therapy
gene
cell adhesion molecules
tumor progression
tumor suppressor
Opis:
Multiple and diverse cell adhesion molecules take part in intercellular and cell-extracellular matrix interactions of cancer. Cancer progression is a multi-step process in which some adhesion molecules play a pivotal role in the development of recurrent, invasive, and distant metastasis. A growing body of evidence indicates that alterations in the adhesion properties of neoplastic cells play a pivotal role in the development and progression of cancer. Loss of intercellular adhesion and the desquamation of cells from the underlying lamina propria allows malignant cells to escape from their site of origin, degrade the extracellular matrix, acquire a more motile and invasion phenotype, and finally, invade and metastasize. In addition to participating in tumor invasiveness and metastasis, adhesion molecules regulate or significantly contribute to a variety of functions including signal transduction, cell growth, differentiation, site-specific gene expression, morphogenesis, immunologic function, cell motility, wound healing, and inflammation. Cell adhesion molecule (CAM), a diverse system of transmembrane glycoproteins has been identified that mediates the cell-cell and cell-extracellular matrix adhesion and also serves as the receptor for different kinds of virus. We summarize recent progress regarding the role of CAM, particularly, immunoglobulin-CAMs and cadherins in the progression of cancer and discuss the potential application of CAMs in the development of cancer therapy mainly on urogenital cancer.
Źródło:
Acta Biochimica Polonica; 2004, 51, 2; 445-457
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Quorum Sensing Materials as New Ligand for Palladium Catalyzed Migita-Kosugi-Stille Polycondensation
Autorzy:
Wang, A.
Toyofuku, M.
Nomura, N.
Goto, H.
Powiązania:
https://bibliotekanauki.pl/articles/412569.pdf
Data publikacji:
2014
Wydawca:
Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
Tematy:
signal molecules
quorum sensing
Migita-Kosugi-Stille coupling
π-conjugated polymers
Opis:
Signal molecules for quorum sensing are employed for ligands to palladium. The complex can be used as a catalyst. Migita-Kosugi-Stille coupling reactions are driven by using a series of N-(3- oxo-acyl)-L-homoserine lactones as ligands coordinating with Pd. Catalysis of [Pd-(signal molecules for quorum sensing), or Pd/QS] allows production of conjugated polymers with light-emitting functions.
Źródło:
International Letters of Chemistry, Physics and Astronomy; 2014, 13, 1; 62-70
2299-3843
Pojawia się w:
International Letters of Chemistry, Physics and Astronomy
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Detonation Performance of Oxygen-rich Trinitromethylsubstituted Pyrazoles: an in-silico Investigation
Autorzy:
Naithani, N.
George, B. K.
Powiązania:
https://bibliotekanauki.pl/articles/358132.pdf
Data publikacji:
2018
Wydawca:
Sieć Badawcza Łukasiewicz - Instytut Przemysłu Organicznego
Tematy:
nitropyrazole
aminonitropyrazoles
detonation velocity
detonation pressure
density functional theory
high energy molecules
Opis:
A new class of high energy molecules was designed and their detonation properties were evaluated using thermo-chemical parameters obtained from quantum chemical calculations at B3LYP/6-31G(d,p) level. The designed molecules exhibited high density, positive oxygen balance and excellent detonation properties. The impact sensitivity of these molecules, in terms of H50 values, was also evaluated from structural correlations. Among these, 3,4,5-tris(trinitromethyl)1H-pyrazol-1-amine (N13) showed the highest detonation pressure (40.67 GPa) and highest detonation velocity (9.17 km/s), though it exhibited high impact sensitive (H50 = 15 cm). Interestingly, 4,5-dinitro-3-(trinitromethyl)-1H-pyrazol-1-amine (N01) (detonation pressure 39.69 GPa; detonation velocity 9.23 km/s) was found to be an ideal high energy molecule with a near zero oxygen balance. The H50 value of N01 was predicted to be 64 cm, which is higher in magnitude, indicating a lower sensitivity than that of the conventionally used RDX (H50 = 26 cm).
Źródło:
Central European Journal of Energetic Materials; 2018, 15, 4; 537-533
1733-7178
Pojawia się w:
Central European Journal of Energetic Materials
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Crystal Structure Prediction and Charge Density Distribution of Highly Energetic Dimethylnitraminotetrazole: a First Step for the Design of High Energy Density Materials
Autorzy:
Arputharaj, D. S.
Srinivasan, P.
Asthana, S. N.
Pawar, R. B.
Kumaradhas, P.
Powiązania:
https://bibliotekanauki.pl/articles/358205.pdf
Data publikacji:
2012
Wydawca:
Sieć Badawcza Łukasiewicz - Instytut Przemysłu Organicznego
Tematy:
energetic materials
crystal structure prediction
charge density analysis
atoms in molecules
electrostatic potential
Opis:
The crystal structure of dimethylnitraminotetrazole has been predicted, based on systematically searching for densely packed structures within common organic crystal coordination types, followed by lattice energy minimization. The predicted crystal structures almost match the reported crystal structure determined by X-ray diffraction analysis. To understand the effect of the initial molecular geometry on the crystal packing, the crystal structure simulation was carried out for molecules taken from different environments, such as the X-ray structure (crystal field) and also from ab initiocalculations (gas phase). The predicted crystal structures from both environments are very similar to the reported X-ray structure with a maximum deviation of 4.5%. The crystal density predicted from both methods is close to that reported. The bond topological, energetic and electrostatic properties of the isolated molecule from the predicted crystal structure have been determined using Bader's theory of atoms in molecules. The bond topological characterization reveals that the C-N bond is the weakest bond in the molecule. A large electronegative potential is found in the vicinity of the NO2group and the nitrogen-rich region of the tetrazole ring; these are probably the reactive sites of this molecule.
Źródło:
Central European Journal of Energetic Materials; 2012, 9, 3; 201-217
1733-7178
Pojawia się w:
Central European Journal of Energetic Materials
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Distribution of gas molecules by their temperatures
Autorzy:
Golovkin, Boris Georgievich
Powiązania:
https://bibliotekanauki.pl/articles/1030475.pdf
Data publikacji:
2020
Wydawca:
Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
Tematy:
Clapeyron equation
Maxwell distribution
distribution of molecules by temperatures
gas density
gas pressure
Opis:
A formula is derived for the distribution of gas molecules over their temperatures depending on the total temperature of the gas. Formulas are proposed for the distribution of velocities and kinetic energies of gas molecules depending on the pressure and density of the gas. It is shown that these formulas are equivalent to the formulas of the corresponding Maxwell distributions, which depend only on temperature. A formula is derived for the distribution of the mean free paths of gas molecules depending only on the gas density. An example of calculating the distribution of gas molecules by their temperatures is given.
Źródło:
World Scientific News; 2020, 144; 89-102
2392-2192
Pojawia się w:
World Scientific News
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Distribution of the lengths of tree paths of gas molecules
Autorzy:
Golovkin, B. G.
Powiązania:
https://bibliotekanauki.pl/articles/1075713.pdf
Data publikacji:
2019
Wydawca:
Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
Tematy:
distribution of molecules
gas
mean free path
pressure
radius of the molecule
temperature
Opis:
It is shown that the formula available in the literature for the distribution of the mean free paths of gas molecules, independent of pressure and temperature, produces obviously incorrect results. Accordingly, a conclusion is given for another formula for a given distribution, which depends on the size of the gas molecules, as well as temperature and pressure. In accordance with this formula, the distribution curve for oxygen at 1000 K and pressures 1 and 0.001 atm has been calculated.
Źródło:
World Scientific News; 2019, 119; 243-247
2392-2192
Pojawia się w:
World Scientific News
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Bending Behaviour of LLDPE Monofilaments Depending on Cold Drawing and Composition of the LLDPEs
Właściwości charakteryzujące zginanie monofilamentów LLDPE w zależności od stopnia zimnego rozciągu i składu polimeru
Autorzy:
Kolgjini, B.
Schoukens, G.
Shehi, E.
Kiekens, P.
Powiązania:
https://bibliotekanauki.pl/articles/232591.pdf
Data publikacji:
2013
Wydawca:
Sieć Badawcza Łukasiewicz - Instytut Biopolimerów i Włókien Chemicznych
Tematy:
polyethylene
draw ratio
resilience
monofilaments
tie molecules
polietylen
współczynnik rozciągania
sprężystość
włókna
cząsteczki krawata
Opis:
The behaviour of the pile layer of artificial turf is an important element for the performance of artificial turf. As a top layer, it is constantly under deformation, with the most possible being bending . The bending behaviour of monofilaments of linear low density polyethylene (LLDPE) is strongly influenced by the processing parameters, the type of polymer, and geometrical factors, which in combination with each other seem to have a strong influence on the behaviour of the final product. From the results obtained, the use of octene instead of hexene as a monomer yields better results for resilience due to a higher concentration of intrafibrillar tie molecules for the same degree of DSC crystallinity of the LLDPEs. The increase in the final cross section of monofilaments based on the same LLPDPEs resulted in a decrease in the intrafibrillar tie molecules due to a slower cooling after melt extrusion.
Badania dotyczyły obróbki wykańczalniczej jedwabiu naturalnego. Mikrostruktura jedwabiu była badana za pomocą skaningowej mikroroskopii elektronowej, a właściwości mechaniczne testowane były klasyczną zrywarką firmy Instron, podczas gdy strukturę krystaliczną analizowano za pomocą spektroskopii w podczerwieni (FTIR) oraz rozproszenia promieniowania rentgenowskiego. Wyniki pozwoliły wytypować najlepszą w danych warunkach metodę obróbki.
Źródło:
Fibres & Textiles in Eastern Europe; 2013, 4 (100); 23-30
1230-3666
2300-7354
Pojawia się w:
Fibres & Textiles in Eastern Europe
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Physical meaning temperature of gas and separate molecule
Autorzy:
Golovkin, B. G.
Powiązania:
https://bibliotekanauki.pl/articles/1157177.pdf
Data publikacji:
2018
Wydawca:
Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
Tematy:
distribution of molecules by temperature
gas cell
mean free path
temperature of a molecule
Opis:
Starting from the equation of state of the Clapeyron gas, it is shown that the temperature of a monatomic molecule of radius and mass moving with velocity is equal to , where: l are the length of a molecule without collisions, the Boltzmann constant, the kinetic energy of the molecule. The physical meaning of the temperature of a molecule should be understood as the kinetic energy that it has in the path without collisions l. The dimension of temperature coincides with the size of energy, but quantitatively the energy differs by the presence of a dimensionless factor , characterizing the motion of a molecule in fractions of its radius. Based on the temperatures of the individual molecules and their relative amounts contained in the gas, a formula is proposed for the overall gas temperature, for any, even nonequilibrium, distribution. The physical meaning of the gas temperature is determined by the product of the mean kinetic energy, the average mean free path of its molecules, and their size.
Źródło:
World Scientific News; 2018, 94, 2; 313-320
2392-2192
Pojawia się w:
World Scientific News
Dostawca treści:
Biblioteka Nauki
Artykuł
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