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Wyszukujesz frazę "molecular response" wg kryterium: Temat


Wyświetlanie 1-5 z 5
Tytuł:
Natural variation in ozone induced cell death in Arabidopsis
Autorzy:
Leppala, J.
Brosche, M.
Powiązania:
https://bibliotekanauki.pl/articles/80797.pdf
Data publikacji:
2013
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
conference
natural variation
atmospheric pollutant
ozone
reactive oxygen species
programmed cell death
molecular response
Arabidopsis thaliana
quantitative trait locus
Źródło:
BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology; 2013, 94, 2
0860-7796
Pojawia się w:
BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Immune signalling and vesicular trafficking – intertwining networks regulated by E3 ubiquitin ligases
Autorzy:
Stegmann, M.
Furlan, G.
Anderson, R.G.
Ichimura, K.
McDowell, J.M.
Shirasu, K.
Trujillo, M.
Powiązania:
https://bibliotekanauki.pl/articles/80842.pdf
Data publikacji:
2013
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
conference
pattern recognition receptor
pathogen-associated molecular pattern
ubiquitin ligase
subunit
exocytosis
immune response
vesicular trafficking
Źródło:
BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology; 2013, 94, 3
0860-7796
Pojawia się w:
BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
In silico study by using ProTox-II webserver for oral acute toxicity, organ toxicity, immunotoxicity, genetic toxicity endpoints, nuclear receptor signalling and stress response pathways of synthetic pyrethroids
Autorzy:
Ghosh, Subhasis
Tripathi, Puja
Talukdar, Partha
Talapatra, Soumendra Nath
Powiązania:
https://bibliotekanauki.pl/articles/1065392.pdf
Data publikacji:
2019
Wydawca:
Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
Tematy:
In silico study
Molecular mechanism of toxicity
Nuclear receptor signalling and stress response pathways
Predictive toxicology
Synthetic pyrethroids
Opis:
Till date, it is well-known that synthetic pyrethroids are safe to mammal but toxic to non-mammals. The present objective was an in silico study to detect oral acute toxicity, organ toxicity, immunotoxicity, genetic toxicity endpoints, nuclear receptor signalling, and stress response pathways of common synthetic pyrethroids by using ProTox-II webserver. The chemical compounds especially different synthetic pyrethroids such as pyrethrin I, Cinerin I and Jasmolin I (esters of Chrysanthemic acid), Pyrethrin-II, Cinerin II and Jasmolin II (Esters of Pyrethric acid), type I pyrethroids (esters without alpha-cyano group) such as allethrin, resmethrin, permethrin and bifenthrin and type II pyrethroids (esters with alpha-cyano group) such as fenvalerate, cyhalothrin, cypermethrin and deltamethrinwere selected from available literature. ProTox-II webserver was used for toxicological assessment in organism, organs, cell and gene level along with molecular mechanisms of toxicity. The predictive results for the toxicity of common synthetic pyrethroids compounds, Deltamethrin showed highly toxic compound among 14 compounds as fatal if swallowed as class II followed by Cypermethrin, Cyhalothrin, Bifenthrin, Resmethrin, Fenvalerate and Permethrin but hepatotoxic potential was only Deltamethrin and Fenvalerate while immunotoxic was obtained Permethrin. On the other hand, none of the compounds were obtained cytotoxic and carcinogenic but 9 compounds viz. Pyrethrin I, II Cinerin I, II, Jasmolin I, II, Allethrin, Resmethrin and Permethrin were observed mutagenic active. In case of NR signalling pathways, all compounds were inactive but eight compounds such as Pyrethrin I, II, Cinerin I, II, Jasmolin I, II, Allethrin and Resmethrin were obtained nrf2/ARE and HSE active while MMP active compounds were obtained Fenvalerate, Cyhalothrin and Deltamethrin respectively. For p53 and ATAD5 parameters, all fourteen compounds such as were obtained inactive. In conclusion, the present predictive results are suitable for academician, researchers, industries, etc. those who are making drugs and environmental chemicals. This web server helps faster screening of large numbers of compounds within short duration and no animal testing. This present in silico study easily detects toxin(s), which can be validated in future through in vitro and in vivo experimental assay.
Źródło:
World Scientific News; 2019, 132; 35-51
2392-2192
Pojawia się w:
World Scientific News
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Molecular mechanism of chloroplastic H2O2-mediated stress response in Arabidopsis
Autorzy:
Maruta, T.
Noshi, M.
Toida, E.
Tamoi, M.
Yamato, K.
Sawa, Y.
Ishikawa, T.
Shigeoka, S.
Powiązania:
https://bibliotekanauki.pl/articles/80030.pdf
Data publikacji:
2013
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
conference
hydrogen peroxide
molecular mechanism
stress response
thylakoid membrane
ascorbate peroxidase
Arabidopsis
plant
photooxidative stress
oxidative stress
salicylic acid
Źródło:
BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology; 2013, 94, 2
0860-7796
Pojawia się w:
BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
High-throughput screening of stomatal responses to biotic stresses reveals new components of immune signalling
Autorzy:
McLachlan, D.
Bourdais, G.
Zhou, J.
Robatzek, S.
Powiązania:
https://bibliotekanauki.pl/articles/80863.pdf
Data publikacji:
2013
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
conference
high-throughput screening
stomatal response
biotic stress
abiotic stress
carbon dioxide flux
pathogen-associated molecular pattern
signalling
guard cell
Arabidopsis
Źródło:
BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology; 2013, 94, 2
0860-7796
Pojawia się w:
BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology
Dostawca treści:
Biblioteka Nauki
Artykuł
    Wyświetlanie 1-5 z 5

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