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Wyszukujesz frazę "microarray analysis" wg kryterium: Temat


Wyświetlanie 1-10 z 10
Tytuł:
Transcriptome signature of the lactation process, identified by meta-analysis of microarray and RNA-Seq data
Autorzy:
Farhadian, M.
Rafat, S.A.
Hasanpur, K.
Ebrahimie, E.
Powiązania:
https://bibliotekanauki.pl/articles/80629.pdf
Data publikacji:
2018
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
transcriptome
lactation
milk production
microarray
expression analysis
cDNA synthesis
RNA sequence
gene expression
Źródło:
BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology; 2018, 99, 2
0860-7796
Pojawia się w:
BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Pathogenesis of middle ear acquired cholesteatoma in the light of the research using high throughput, “omics”, technologies of molecular biology
Autorzy:
Makuszewska, Maria
Bartoszewicz, Robert
Niemczyk, Kazimierz
Powiązania:
https://bibliotekanauki.pl/articles/1399639.pdf
Data publikacji:
2019
Wydawca:
Index Copernicus International
Tematy:
aquired cholesteatoma
gene expression
microarray
molecular biology
pathogenesis
proteomic analysis
Opis:
Cholesteatoma is described as cystic lesion consisting of keratinizing squamous cell epithelium, filed with keratin debris, surrounded by inflammatory fibrous tissue, gradually expanding in the middle ear and causing destruction of neighboring bones. This paper presents brief review of existing hypotheses explaining its etiology in the light of the researches using high throughput, “omics”, technologies of molecular biology. Classic theories of pathogenesis of acquired cholesteatoma as: immigration, squamous metaplasia, basal cell hyperplasia or invagination theory have not been able to explain fully all pathological processes observed in cholesteatoma tissue. This also concerns the newer concepts that cholesteatoma is a result of mucosal traction generated by interaction of migrating opposing surfaces, a natural attempt by the body to cure the underlying inflammation in the cavity or chronic wound healing process triggered by micro defects in the basement membrane of the epithelium in the retraction pocket. Introduction of high-throughput, “omics”, technologies of molecular biology to the studies under cholesteatoma pathogenesis allowed identification of cholesteatoma-related gene expression signatures using full-genome microarrays as well as proteomic analysis of cholesteatoma. Those studies confirmed known pathological processes observed in cholesteatoma tissue such as: high proliferative activity, decreased signal transduction, active immunological response, alterations in the extracellular matrix, increased expression of proinflammatory cytokines, neovascularization and may others. This technique allows precise and complete insight into molecular mechanisms in those processes. However, it is still unknown what is the cause that trigger epithelial hyperplasia, inhibited migration and inflammatory response in the preexisting retraction pocket.
Źródło:
Polski Przegląd Otorynolaryngologiczny; 2019, 8, 3; 14-19
2084-5308
2300-7338
Pojawia się w:
Polski Przegląd Otorynolaryngologiczny
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Analysis of expression profiles of barley, medicago and soybean galactinol synthase through microarray data integration
Autorzy:
Paukszto, L.
Myszczynski, K.
Gojlo, E.
Jastrzebski, J.P.
Pupel, P.
Podlinski, P.
Powiązania:
https://bibliotekanauki.pl/articles/79948.pdf
Data publikacji:
2013
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
conference
expression analysis
barley
Medicago truncatula
soybean
Hordeum vulgare
Glycine max
galactinol synthase
microarray
biosynthesis
gene expression
Źródło:
BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology; 2013, 94, 3
0860-7796
Pojawia się w:
BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Impact of DNA microarray data transformation on gene expression analysis - comparison of two normalization methods
Autorzy:
Schmidt, Marcin
Handschuh, Luiza
Zyprych, Joanna
Szabelska, Alicja
Olejnik-Schmidt, Agnieszka
Siatkowski, Idzi
Figlerowicz, Marek
Powiązania:
https://bibliotekanauki.pl/articles/1039855.pdf
Data publikacji:
2011
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
microarray
data normalization
enterocyte
transcriptome analysis
probiotic
adhesion
gene expression profiling
Opis:
Two-color DNA microarrays are commonly used for the analysis of global gene expression. They provide information on relative abundance of thousands of mRNAs. However, the generated data need to be normalized to minimize systematic variations so that biologically significant differences can be more easily identified. A large number of normalization procedures have been proposed and many softwares for microarray data analysis are available. Here, we have applied two normalization methods (median and loess) from two packages of microarray data analysis softwares. They were examined using a sample data set. We found that the number of genes identified as differentially expressed varied significantly depending on the method applied. The obtained results, i.e. lists of differentially expressed genes, were consistent only when we used median normalization methods. Loess normalization implemented in the two software packages provided less coherent and for some probes even contradictory results. In general, our results provide an additional piece of evidence that the normalization method can profoundly influence final results of DNA microarray-based analysis. The impact of the normalization method depends greatly on the algorithm employed. Consequently, the normalization procedure must be carefully considered and optimized for each individual data set.
Źródło:
Acta Biochimica Polonica; 2011, 58, 4; 573-580
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
The methods of normalization used in the analysis of two-color microarrays
Metody normalizacji w analizie dwukolorowych mikromacierzy
Autorzy:
Siatkowski, I.
Zyprych, J.
Handschuh, L.
Figlerowicz, M.
Powiązania:
https://bibliotekanauki.pl/articles/9613.pdf
Data publikacji:
2009
Wydawca:
Uniwersytet Przyrodniczy w Lublinie. Katedra Zastosowań Matematyki i Informatyki
Tematy:
normalization method
analysis
microarray analysis
bioconductor
Źródło:
Colloquium Biometricum; 2009, 39
1896-7701
Pojawia się w:
Colloquium Biometricum
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Microarray Inspector: tissue cross contamination detection tool for microarray data
Autorzy:
Stępniak, Piotr
Maycock, Matthew
Wojdan, Konrad
Markowska, Monika
Perun, Serhiy
Srivastava, Aashish
Wyrwicz, Lucjan
Świrski, Konrad
Powiązania:
https://bibliotekanauki.pl/articles/1039460.pdf
Data publikacji:
2013
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
microarray
transcription profiling
contamination analysis
adipose tissue
cancer
data quality
Opis:
Microarray technology changed the landscape of contemporary life sciences by providing vast amounts of expression data. Researchers are building up repositories of experiment results with various conditions and samples which serve the scientific community as a precious resource. Ensuring that the sample is of high quality is of utmost importance to this effort. The task is complicated by the fact that in many cases datasets lack information concerning pre-experimental quality assessment. Transcription profiling of tissue samples may be invalidated by an error caused by heterogeneity of the material. The risk of tissue cross contamination is especially high in oncological studies, where it is often difficult to extract the sample. Therefore, there is a need of developing a method detecting tissue contamination in a post-experimental phase. We propose Microarray Inspector: customizable, user-friendly software that enables easy detection of samples containing mixed tissue types. The advantage of the tool is that it uses raw expression data files and analyses each array independently. In addition, the system allows the user to adjust the criteria of the analysis to conform to individual needs and research requirements. The final output of the program contains comfortable to read reports about tissue contamination assessment with detailed information about the test parameters and results. Microarray Inspector provides a list of contaminant biomarkers needed in the analysis of adipose tissue contamination. Using real data (datasets from public repositories) and our tool, we confirmed high specificity of the software in detecting contamination. The results indicated the presence of adipose tissue admixture in a range from approximately 4% to 13% in several tested surgical samples.
Źródło:
Acta Biochimica Polonica; 2013, 60, 4; 647-655
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Identification of candidate genes related to aroma in rice by analyzing the microarray data of highly aromatic and nonaromatic recombinant inbred line bulks
Autorzy:
Zinati, Z.
Delavari, A.
Powiązania:
https://bibliotekanauki.pl/articles/80716.pdf
Data publikacji:
2019
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
rice
Oryza sativa
aroma
aroma-related gene
gene ontology enrichment analysis
microarray analysis
protein-protein interaction
protein interaction network
inbred line
Źródło:
BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology; 2019, 100, 3
0860-7796
Pojawia się w:
BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Identification of novel genes potentially involved in rice (Oryza sativa L.) drought tolerance
Autorzy:
Zinati, Z.
Powiązania:
https://bibliotekanauki.pl/articles/80145.pdf
Data publikacji:
2017
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
microarray analysis
Oryza sativa
rice
drought tolerance
drought stress
transcription factor
gene encoding
quantitative trait locus
Źródło:
BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology; 2017, 98, 3
0860-7796
Pojawia się w:
BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Elevated CO2 mitigates the impact of a combination of heat wave and drought in Arabidopsis thaliana
Autorzy:
Zinta, G.
AbdElgawad, H.
Domagalska, M.
Vergauwen, L.
Nijs, I.
Beemster, G.
Asard, H.
Janssens, I.
Powiązania:
https://bibliotekanauki.pl/articles/80475.pdf
Data publikacji:
2013
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
conference
carbon dioxide
heat wave
drought stress
Arabidopsis thaliana
photosynthesis
microarray analysis
Źródło:
BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology; 2013, 94, 2
0860-7796
Pojawia się w:
BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Transcriptome sequencing: next generation approach to RNA functional analysis
Autorzy:
Zmienko, A.
Jackowiak, P.
Figlerowicz, M.
Powiązania:
https://bibliotekanauki.pl/articles/81137.pdf
Data publikacji:
2011
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
RNA molecule
functional analysis
RNA sequence
transcriptome
isoform
DNA microarray
qualitative change
quantitative change
gene expression
hybridization
oligonucleotide probe
Źródło:
BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology; 2011, 92, 4
0860-7796
Pojawia się w:
BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology
Dostawca treści:
Biblioteka Nauki
Artykuł
    Wyświetlanie 1-10 z 10

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