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Wyszukujesz frazę "microarray analysis" wg kryterium: Temat

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    Tytuł:
    The methods of normalization used in the analysis of two-color microarrays
    Metody normalizacji w analizie dwukolorowych mikromacierzy
    Autorzy:
    Siatkowski, I.
    Zyprych, J.
    Handschuh, L.
    Figlerowicz, M.
    Powiązania:
    https://bibliotekanauki.pl/articles/9613.pdf
    Data publikacji:
    2009
    Wydawca:
    Uniwersytet Przyrodniczy w Lublinie. Katedra Zastosowań Matematyki i Informatyki
    Tematy:
    normalization method
    analysis
    microarray analysis
    bioconductor
    Źródło:
    Colloquium Biometricum; 2009, 39
    1896-7701
    Pojawia się w:
    Colloquium Biometricum
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Elevated CO2 mitigates the impact of a combination of heat wave and drought in Arabidopsis thaliana
    Autorzy:
    Zinta, G.
    AbdElgawad, H.
    Domagalska, M.
    Vergauwen, L.
    Nijs, I.
    Beemster, G.
    Asard, H.
    Janssens, I.
    Powiązania:
    https://bibliotekanauki.pl/articles/80475.pdf
    Data publikacji:
    2013
    Wydawca:
    Polska Akademia Nauk. Czytelnia Czasopism PAN
    Tematy:
    conference
    carbon dioxide
    heat wave
    drought stress
    Arabidopsis thaliana
    photosynthesis
    microarray analysis
    Źródło:
    BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology; 2013, 94, 2
    0860-7796
    Pojawia się w:
    BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Identification of novel genes potentially involved in rice (Oryza sativa L.) drought tolerance
    Autorzy:
    Zinati, Z.
    Powiązania:
    https://bibliotekanauki.pl/articles/80145.pdf
    Data publikacji:
    2017
    Wydawca:
    Polska Akademia Nauk. Czytelnia Czasopism PAN
    Tematy:
    microarray analysis
    Oryza sativa
    rice
    drought tolerance
    drought stress
    transcription factor
    gene encoding
    quantitative trait locus
    Źródło:
    BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology; 2017, 98, 3
    0860-7796
    Pojawia się w:
    BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Identification of candidate genes related to aroma in rice by analyzing the microarray data of highly aromatic and nonaromatic recombinant inbred line bulks
    Autorzy:
    Zinati, Z.
    Delavari, A.
    Powiązania:
    https://bibliotekanauki.pl/articles/80716.pdf
    Data publikacji:
    2019
    Wydawca:
    Polska Akademia Nauk. Czytelnia Czasopism PAN
    Tematy:
    rice
    Oryza sativa
    aroma
    aroma-related gene
    gene ontology enrichment analysis
    microarray analysis
    protein-protein interaction
    protein interaction network
    inbred line
    Źródło:
    BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology; 2019, 100, 3
    0860-7796
    Pojawia się w:
    BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Microarray Inspector: tissue cross contamination detection tool for microarray data
    Autorzy:
    Stępniak, Piotr
    Maycock, Matthew
    Wojdan, Konrad
    Markowska, Monika
    Perun, Serhiy
    Srivastava, Aashish
    Wyrwicz, Lucjan
    Świrski, Konrad
    Powiązania:
    https://bibliotekanauki.pl/articles/1039460.pdf
    Data publikacji:
    2013
    Wydawca:
    Polskie Towarzystwo Biochemiczne
    Tematy:
    microarray
    transcription profiling
    contamination analysis
    adipose tissue
    cancer
    data quality
    Opis:
    Microarray technology changed the landscape of contemporary life sciences by providing vast amounts of expression data. Researchers are building up repositories of experiment results with various conditions and samples which serve the scientific community as a precious resource. Ensuring that the sample is of high quality is of utmost importance to this effort. The task is complicated by the fact that in many cases datasets lack information concerning pre-experimental quality assessment. Transcription profiling of tissue samples may be invalidated by an error caused by heterogeneity of the material. The risk of tissue cross contamination is especially high in oncological studies, where it is often difficult to extract the sample. Therefore, there is a need of developing a method detecting tissue contamination in a post-experimental phase. We propose Microarray Inspector: customizable, user-friendly software that enables easy detection of samples containing mixed tissue types. The advantage of the tool is that it uses raw expression data files and analyses each array independently. In addition, the system allows the user to adjust the criteria of the analysis to conform to individual needs and research requirements. The final output of the program contains comfortable to read reports about tissue contamination assessment with detailed information about the test parameters and results. Microarray Inspector provides a list of contaminant biomarkers needed in the analysis of adipose tissue contamination. Using real data (datasets from public repositories) and our tool, we confirmed high specificity of the software in detecting contamination. The results indicated the presence of adipose tissue admixture in a range from approximately 4% to 13% in several tested surgical samples.
    Źródło:
    Acta Biochimica Polonica; 2013, 60, 4; 647-655
    0001-527X
    Pojawia się w:
    Acta Biochimica Polonica
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Pathogenesis of middle ear acquired cholesteatoma in the light of the research using high throughput, “omics”, technologies of molecular biology
    Autorzy:
    Makuszewska, Maria
    Bartoszewicz, Robert
    Niemczyk, Kazimierz
    Powiązania:
    https://bibliotekanauki.pl/articles/1399639.pdf
    Data publikacji:
    2019
    Wydawca:
    Index Copernicus International
    Tematy:
    aquired cholesteatoma
    gene expression
    microarray
    molecular biology
    pathogenesis
    proteomic analysis
    Opis:
    Cholesteatoma is described as cystic lesion consisting of keratinizing squamous cell epithelium, filed with keratin debris, surrounded by inflammatory fibrous tissue, gradually expanding in the middle ear and causing destruction of neighboring bones. This paper presents brief review of existing hypotheses explaining its etiology in the light of the researches using high throughput, “omics”, technologies of molecular biology. Classic theories of pathogenesis of acquired cholesteatoma as: immigration, squamous metaplasia, basal cell hyperplasia or invagination theory have not been able to explain fully all pathological processes observed in cholesteatoma tissue. This also concerns the newer concepts that cholesteatoma is a result of mucosal traction generated by interaction of migrating opposing surfaces, a natural attempt by the body to cure the underlying inflammation in the cavity or chronic wound healing process triggered by micro defects in the basement membrane of the epithelium in the retraction pocket. Introduction of high-throughput, “omics”, technologies of molecular biology to the studies under cholesteatoma pathogenesis allowed identification of cholesteatoma-related gene expression signatures using full-genome microarrays as well as proteomic analysis of cholesteatoma. Those studies confirmed known pathological processes observed in cholesteatoma tissue such as: high proliferative activity, decreased signal transduction, active immunological response, alterations in the extracellular matrix, increased expression of proinflammatory cytokines, neovascularization and may others. This technique allows precise and complete insight into molecular mechanisms in those processes. However, it is still unknown what is the cause that trigger epithelial hyperplasia, inhibited migration and inflammatory response in the preexisting retraction pocket.
    Źródło:
    Polski Przegląd Otorynolaryngologiczny; 2019, 8, 3; 14-19
    2084-5308
    2300-7338
    Pojawia się w:
    Polski Przegląd Otorynolaryngologiczny
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Impact of DNA microarray data transformation on gene expression analysis - comparison of two normalization methods
    Autorzy:
    Schmidt, Marcin
    Handschuh, Luiza
    Zyprych, Joanna
    Szabelska, Alicja
    Olejnik-Schmidt, Agnieszka
    Siatkowski, Idzi
    Figlerowicz, Marek
    Powiązania:
    https://bibliotekanauki.pl/articles/1039855.pdf
    Data publikacji:
    2011
    Wydawca:
    Polskie Towarzystwo Biochemiczne
    Tematy:
    microarray
    data normalization
    enterocyte
    transcriptome analysis
    probiotic
    adhesion
    gene expression profiling
    Opis:
    Two-color DNA microarrays are commonly used for the analysis of global gene expression. They provide information on relative abundance of thousands of mRNAs. However, the generated data need to be normalized to minimize systematic variations so that biologically significant differences can be more easily identified. A large number of normalization procedures have been proposed and many softwares for microarray data analysis are available. Here, we have applied two normalization methods (median and loess) from two packages of microarray data analysis softwares. They were examined using a sample data set. We found that the number of genes identified as differentially expressed varied significantly depending on the method applied. The obtained results, i.e. lists of differentially expressed genes, were consistent only when we used median normalization methods. Loess normalization implemented in the two software packages provided less coherent and for some probes even contradictory results. In general, our results provide an additional piece of evidence that the normalization method can profoundly influence final results of DNA microarray-based analysis. The impact of the normalization method depends greatly on the algorithm employed. Consequently, the normalization procedure must be carefully considered and optimized for each individual data set.
    Źródło:
    Acta Biochimica Polonica; 2011, 58, 4; 573-580
    0001-527X
    Pojawia się w:
    Acta Biochimica Polonica
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Transcriptome signature of the lactation process, identified by meta-analysis of microarray and RNA-Seq data
    Autorzy:
    Farhadian, M.
    Rafat, S.A.
    Hasanpur, K.
    Ebrahimie, E.
    Powiązania:
    https://bibliotekanauki.pl/articles/80629.pdf
    Data publikacji:
    2018
    Wydawca:
    Polska Akademia Nauk. Czytelnia Czasopism PAN
    Tematy:
    transcriptome
    lactation
    milk production
    microarray
    expression analysis
    cDNA synthesis
    RNA sequence
    gene expression
    Źródło:
    BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology; 2018, 99, 2
    0860-7796
    Pojawia się w:
    BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Analysis of expression profiles of barley, medicago and soybean galactinol synthase through microarray data integration
    Autorzy:
    Paukszto, L.
    Myszczynski, K.
    Gojlo, E.
    Jastrzebski, J.P.
    Pupel, P.
    Podlinski, P.
    Powiązania:
    https://bibliotekanauki.pl/articles/79948.pdf
    Data publikacji:
    2013
    Wydawca:
    Polska Akademia Nauk. Czytelnia Czasopism PAN
    Tematy:
    conference
    expression analysis
    barley
    Medicago truncatula
    soybean
    Hordeum vulgare
    Glycine max
    galactinol synthase
    microarray
    biosynthesis
    gene expression
    Źródło:
    BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology; 2013, 94, 3
    0860-7796
    Pojawia się w:
    BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Transcriptome sequencing: next generation approach to RNA functional analysis
    Autorzy:
    Zmienko, A.
    Jackowiak, P.
    Figlerowicz, M.
    Powiązania:
    https://bibliotekanauki.pl/articles/81137.pdf
    Data publikacji:
    2011
    Wydawca:
    Polska Akademia Nauk. Czytelnia Czasopism PAN
    Tematy:
    RNA molecule
    functional analysis
    RNA sequence
    transcriptome
    isoform
    DNA microarray
    qualitative change
    quantitative change
    gene expression
    hybridization
    oligonucleotide probe
    Źródło:
    BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology; 2011, 92, 4
    0860-7796
    Pojawia się w:
    BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
      Wyświetlanie 1-10 z 10

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