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    Wyświetlanie 1-7 z 7
    Tytuł:
    DIPSACUS FULLONUM L. LEAVES AND ROOTS - IDENTIFICATION OF THE COMPONENTS OF THE ESSENTIAL OILS AND ALPHA-AMYLASE INHIBITORY ACTIVITIES OF METHANOLIC EXTRACTS
    Autorzy:
    Witkowska-Banaszczak, Ewa
    Powiązania:
    https://bibliotekanauki.pl/articles/895320.pdf
    Data publikacji:
    2018-08-31
    Wydawca:
    Polskie Towarzystwo Farmaceutyczne
    Tematy:
    essential oil composition
    methanolic extract
    alpha-amylase inhibition
    Opis:
    Abstract: Dipsacus fullonum L. syn. D. sylvestris is a biennial plant from the Dipsacaceae family. It grows in Europe, North Africa and Asia Minor. It has been used in folk medicine mainly to treat Lyme disease. This study was undertaken to identify and compare the components of the essential oils from dried and fresh roots, which are usually applied as medicinal agents, as well as those of the essential oils from dried and fresh leaves, used less frequently. The essential oils from the Dipsacus fullonum leaves and roots were analysed by the GC and GC-MS analysis. 18 components were identified in the essential oil from the fresh leaves, whereas 37 were recognised in the oil from the dried leaves; 10 components were identified in the essential oil from the fresh roots and 40 in that from the dried roots. Phytol was the main component in the essential oil from the leaves, whereas n-hexadecanoic acid was predominant in the roots. The α -amylase inhibition has been proven for methanolic extracts of D. fullonum leaves and roots. The strongest activity was demonstrated by the extract from fresh leaves of D. fullonum and showed an effect about one hundred times weaker than acarbose.
    Źródło:
    Acta Poloniae Pharmaceutica - Drug Research; 2018, 75, 4; 951-957
    0001-6837
    2353-5288
    Pojawia się w:
    Acta Poloniae Pharmaceutica - Drug Research
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Effect of the solvent on the extraction of polyphenols from distillery stillage and on their antioxidant activity
    Autorzy:
    Mikucka, Wioleta
    Zielińska, Magdalena
    Powiązania:
    https://bibliotekanauki.pl/articles/1830630.pdf
    Data publikacji:
    2021-09-29
    Wydawca:
    Uniwersytet Łódzki. Wydawnictwo Uniwersytetu Łódzkiego
    Tematy:
    DPPH assay
    Folin-Ciocalteu
    phenolic content
    methanolic extract
    ethanolic extract
    Opis:
    The increase in the costs of storage and disposal of post-production residues has resulted in the search for new directions for their recycling, which is closely related to the necessity of protecting the natural environment and promoting a circular economy. Moreover, the apparent interest shown by the food market in raw materials with high antioxidant activity implies an increasing use of by-products. The objective of the study was to determine the effect of the type and concentration of the solvent on the efficiency of extracting polyphenols from distillery stillage as well as their antioxidant activity by using several solvents: methanol:water (70:30 v/v), methanol:water (100:0 v/v), ethanol:water (70:30 v/v) or ethanol:water (100:0 v/v). The DPPH radical method was used to determine the antioxidant activity of the obtained extracts. The normalised variable (NV) and statistical measure (MS) were determined, based on which the effectiveness of the solvents was evaluated. The highest polyphenolic content and the antioxidant activity were obtained by using ethanol:water (70:30 v/v) as a solvent in the extraction of polyphenolic compounds from distillery stillage.
    Źródło:
    Acta Universitatis Lodziensis. Folia Biologica et Oecologica; 2021, 17; 54-62
    1730-2366
    2083-8484
    Pojawia się w:
    Acta Universitatis Lodziensis. Folia Biologica et Oecologica
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Berberine from Argemone mexicana L exhibits a broadspectrum antibacterial activity
    Autorzy:
    More, Nilesh
    Kharat, Kiran
    Kharat, Arun
    Powiązania:
    https://bibliotekanauki.pl/articles/1038553.pdf
    Data publikacji:
    2017
    Wydawca:
    Polskie Towarzystwo Biochemiczne
    Tematy:
    antibacterial potentiality
    Argemone mexicana
    aqueous
    methanolic extract
    HPLC
    NMR and phytochemical analysis
    Opis:
    The Argemone mexicana L, commonly found on desolate land in the Marathwada region of Maharashtra state, India, has been used for treating oral cavity infections. We sought to investigate the antimicrobial potential of A. mexicana L. In this study, cold aqueous and methanolic extracts were prepared from the A. mexicana L leaves. These extracts were tested for their antibacterial activities against selected bacterial isolates. The antibacterial activity and MICs were tested using the agar well diffusion method and broth dilution method, respectively. The cold aqueous and methanolic extracts of A. mexicana L leaves inhibited growth of clinical isolates of Staphylococcus aureus, Bacillus cereus, Escherichia coli and Pseudomonas aeruginosa.The antibacterial potentiality of A. mexicana L extracts was compared with Streptomycin - the reference antibiotic used in this study. The active ingredient of antibacterial potentiality within the A. mexicana L extract was purified and characterized by TLC, HPLC and NMR analysis. Structural elucidation of Berberine and its bioactivity both, from the A. mexicana L and commercial preparation, is investigated.
    Źródło:
    Acta Biochimica Polonica; 2017, 64, 4; 653-660
    0001-527X
    Pojawia się w:
    Acta Biochimica Polonica
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Preliminary study on the impact of methanolic extract of Elephantopus scaber Linn. on hair growth promoting effect in rats
    Wstępne badanie wpływu wyciągu metanolowego z Elephantopus scaber Linn. na proces wspomagania wzrostu owłosienia u szczurów
    Autorzy:
    Sahoo, H.B.
    Sagar, R.
    Bhattamisra, S.K.
    Bhaiji, A.
    Powiązania:
    https://bibliotekanauki.pl/articles/72781.pdf
    Data publikacji:
    2013
    Wydawca:
    Instytut Włókien Naturalnych i Roślin Zielarskich
    Tematy:
    methanolic extract
    Elephantopus scaber
    hair growth
    promoting effect
    rat
    hair loss
    baldness zob.alopecia
    alopecia
    Opis:
    Methanolic extract of Elephantopus scaber leaves was investigated for its role in hair growth in experimental rats. The 2% and 5% solution of prepared formulation using methanolic extract was studied for hair growth on wistar rats for 30 days. Minoxidil (2% solution) was taken as a reference standard. The prepared hair oil formulation of methanolic extract significantly (p<0.01) potentiated the hair growth initiation and completion time with dosedependent improvement in skin biopsy, hair length and hair weight. In vitro hair follicles development study showed the significant (p<0.05) improvement in the initiation of new hair follicles. Above mentioned results indicated that the methanolic extract of E. scaber rendered significant hair growth promotive effect.
    Badano wpływ wyciągu metanolowego z liści Elephantopus scaber na wzrost włosów u szczurów laboratoryjnych. Przez 30 dni badano wzrost włosów u szczurów Wistar po podaniu 2% i 5% preparatu sporządzonego z użyciem ekstraktu metanolowego. Substancją kontrolną był minoksidil (roztwór 2 %). Preparat z ekstraktu metanolowego przygotowany na bazie oleju istotnie (p<0,01) zwiększał inicjację wzrostu włosów i przyspieszał jego zakończenie. Podczas biopsji odnotowano też zależną od dawki poprawę stanu skóry, długości włosów i zwiększenie masy włosów. Podczas badaniu in vitro wykazano istotną (p<0,05) poprawę tworzenia się nowych mieszków włosowych. Powyższe wyniki wskazują, że wyciąg metanolowy z E. scaber może istotnie zwiększać porost włosów.
    Źródło:
    Herba Polonica; 2013, 59, 2
    0018-0599
    Pojawia się w:
    Herba Polonica
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Evaluation of antiepileptic activity of methanolic leaves extract of Tragia involucrata Linn. in mice
    Autorzy:
    Varma, G.G.
    Mathai, B.K.
    Das, K.
    Gowda, G.
    Rammohan, S.
    Einstein, J.W.
    Powiązania:
    https://bibliotekanauki.pl/articles/11927.pdf
    Data publikacji:
    2014
    Wydawca:
    Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
    Tematy:
    antiepileptic drug
    antiepileptic activity
    methanolic extract
    leaf
    plant extract
    Tragia involucrata
    Indian stinging nettle
    mice
    mouse
    anticonvulsant action
    pentylenetetrazol
    picrotoxin
    Opis:
    The present investigation was aimed to study an antiepileptic activity of methanolic extract of Tragia involucrata Linn in mice. In vivo screening models like maximal electroshock-induced convulsion (MES), pentylenetetrazole (PTZ) and picrotoxin (PTX) induced models are used to evaluate the antiepileptic effects of the extracts. The biochemical estimation was done by measuring the lipid peroxidation and reduced glutathione (GSH). In the MES induced convulsion, methanolic extract of Tragia involucrata (METI) at high dose (800 mg/kg body weight), showed high significant inhibition on tonic hind limb extension (THLE, 6.83 ±0.30***) and decrease in duration of stupor period (108.7 ±6.53***). In PTZ and PTX induced model METI (400 mg/kg and 800 mg/kg) showed significant delay on the onset of convulsions, decreased duration of convulsion and reduced mortality significantly. It also showed significant decrease in brain MDA level in lipid peroxidation profile, and increase in the brain glutathione levels in mice against PTZ induced convulsion. The results confirmed that Tragia involucrata Linn possesses dose dependent antiepileptic activity.
    Źródło:
    International Letters of Natural Sciences; 2014, 12, 2
    2300-9675
    Pojawia się w:
    International Letters of Natural Sciences
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Effect of heating on antioxidative activity of rapeseed and evening primrose extracts
    Autorzy:
    Zadernowski, R.
    Nowak-Polakowska, H.
    Konopka, I.
    Powiązania:
    https://bibliotekanauki.pl/articles/1372684.pdf
    Data publikacji:
    1996
    Wydawca:
    Instytut Rozrodu Zwierząt i Badań Żywności Polskiej Akademii Nauk w Olsztynie
    Tematy:
    evening primrose
    Oenothera biennis
    heating
    food technology
    methanolic extract
    natural antioxidant
    plant oil
    polyphenol
    antioxidant activity
    phenolic acid
    plant
    rapeseed
    Opis:
    The composition and effect of heating (60°-110°C) on antioxidative activity in plant oil of rapeseed (RE) and evening primrose (EPE) methanolic extracts were studied. Different phenolics characterized the extracts. The EPE contained about 10-fold higher amount of phenolics (862.2 g/kg extract) than RE; flavanols (683.8 g/kg) and proanthocyanidins (760.1 g/kg) prevailed in the former and phenolic acid derivatives in the latter. The phenolic compounds of both extracts differed with the fenolic acids composition. Sinapic acid prevailed in rapeseed phenolics and protocatechic and gentisic acids in evening primrose phenolics. Both extracts had generally similar antioxidative activity in the temperature ranging from 60°C to 80°C with the oil peroxide values from 3.5 mmol O/kg to 5.0 mmol O/kg compared to the range of 6.0-7.0 mmol O/kg in control oils. The temperatures above 80°C decreased the antioxidative activity of both extracts and even made them to be prooxidative.
    Badano skład i wpływ temperatury (60-110°C) na właściwości przeciwutleniające ekstraktów metanolowych nasion rzepaku i wiesiołka. Stwierdzono, że olej tych nasion zawierał tokoferole, głównie α- i y-, w ilości 0,65 g/kg (rzepak) i 0,45 g/kg (wiesiołek) (tab. 1), a ekstrakty metanolowe nasion charakteryzowały się różnymi formami związków fenolowych. W porównaniu z ekstraktem rzepakowym, ekstrakt wiesiołka zawierał około 10-krotnie więcej związków fenolowych, wśród których dominowały flawanole i proantocyjanidyny (tab. 2). Kwasy fenolowe i ich pochodne dominowały w ekstrakcie rzepakowym. Związki fenolowe ekstraktów różniły się składem kwasów fenolowych (rys. 1). Ekstrakty metanolowe obu nasion wykazywały się generalnie taką samą aktywnością przeciwutleniającą (rys. 2). W temperaturze powyżej 80°C aktywność przeciwutleniająca ekstraktów zanikała lub nawet obserwowano przyśpieszenie procesu utleniania oleju roślinnego.
    Źródło:
    Polish Journal of Food and Nutrition Sciences; 1996, 05, 2; 13-21
    1230-0322
    2083-6007
    Pojawia się w:
    Polish Journal of Food and Nutrition Sciences
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Effects of Artemisia annua methanolic extract on the enzymatic components of intermediary metabolism and the antioxidant system of Pseudococcus viburni Signoret
    Autorzy:
    Ramzi, S.
    Seraji, A.
    Gonbad, R.A.
    Mirhaghparast, K.
    Mojib-Haghghadam, Z.
    Powiązania:
    https://bibliotekanauki.pl/articles/65893.pdf
    Data publikacji:
    2018
    Wydawca:
    Polska Akademia Nauk. Czytelnia Czasopism PAN
    Tematy:
    Artemisia annua
    methanolic extract
    enzymatic component
    intermediary metabolism
    antioxidant system
    Pseudococcus viburni
    mealybug
    obscure mealybug
    tuber mealybug zob.obscure mealybug
    plant pest
    Opis:
    Toxicity and physiological alterations were determined in Pseudococcus viburni nymphs treated with Artemisia annua methanolic extract. The leaf dipping bioassay showed LC50 values of 0.287% and 0.194% 24 and 48 hours post-exposure. Activities of general esterases were significantly higher in the control nymphs than in those which had been treated except for the 48 h time interval using α-naphtyl acetate. The activity of glutathione S-transferase using CDNB (1-chloro-2,4-dinitrobenzene) in the control nymphs, was significantly higher than in the control at both time intervals while no significant difference was observed after 24 h in addition to the higher enzymatic activity in the treated nymphs after 48 h. All three aminotransferases were significantly more active in the control nymphs except for time intervals of 24 h for γ-glutamyl transferase and 48 h for alanine aminotransferase. Higher activities of lactate dehydrogenase, acid- and alkaline phosphatase were found in the control nymphs than in treated nymphs for all time intervals. Activities of the enzymes involved in the antioxidant system including catalase, peroxidase, superoxide dismutase, ascorbate peroxidase and glucose-6-phosphate dehydrogenase was increased in the treated nymphs compared to the control. Results of the current study demonstrated toxic effects of A. annua methanolic extract on P. viburni nymphs causing mortality and physiological turbulences.
    Źródło:
    Journal of Plant Protection Research; 2018, 58, 3
    1427-4345
    Pojawia się w:
    Journal of Plant Protection Research
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
      Wyświetlanie 1-7 z 7

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