Temat: markers - Katalog OPAC zbiorów

Skocz do pozycji: 1.

Tytuł:: Стилистика в свете типов речевой культуры
Autorzy:: Сиротинина, Ольга O.
Powiązania:: https://bibliotekanauki.pl/articles/1925911.pdf
Data publikacji:: 2005
Wydawca:: Uniwersytet Opolski
Tematy:: stylistics
functional stylistics
literaiy stylistics
practical stylistics
types of speech culture
speech culture markers
Opis:: The рарег is focused оп different aspects of the соггеlatioп between stylistics аnd types of speech сulture. It is argued that апу kind of stylistics studies оnlу the highest type of speech culture common to people who have a perfect command of all language varieties. In other words, stylistics always deals exclusively with the accepted model of good speech. The first part of the paper concentrates on the essence of three branches of stylistics: functional stylistics, literary stylistics, and practical stylistics. Functional stylistics studies functional differentiation of standard language (the Russian equivalent of the English term standard language is numepamypmrn язык). Practical stylistics is aimed at choosing the best synonym.Literary stylistics analyses fictional texts whose authors make a maximum use of language resources. Only people of the fully functional type of speech culture can cope with the above-mentioned tasks.The second part of the paper is devoted to a study of the peculiarities of speech culture markers manifestation in different language varieties. A close analysis of extensive factual data has led the author to the conclusion that speech culture markers are most active in public and fiction discourse and least active in standardized documents and casual everyday conversation.
Źródło:: Stylistyka; 2005, 14; 209-218
1230-2287
2545-1669
Pojawia się w:: Stylistyka
Dostawca treści:: Biblioteka Nauki

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Tytuł:: Лексические средства семантики невыразимого в современном газетном дискурсе
Lexical means of the semantics of the inexpressible in modern newspaper discourse
Autorzy:: Немич, Наталья
Powiązania:: https://bibliotekanauki.pl/articles/1409593.pdf
Data publikacji:: 2020-06-30
Wydawca:: Uniwersytet Łódzki. Wydawnictwo Uniwersytetu Łódzkiego
Tematy:: семантика
лексические средства
невыразимое
непередаваемо
современный газетный дискурс
маркеры отрицания
semantics
lexical means
inexpressible
indescribable
modern newspaper discourse
markers of negation
Opis:: В статье рассматриваются лексические средства семантики невыразимого. Невыразимое – это функционально-семантическая категория русского языка, которая служит для передачи невозможности выразить участниками речи объект речи. Динамичное развитие печатных средств массовой информации оказывает огромное влияние на процесс производства и распространения газетных текстов. Актуальность нашего исследования обусловлена тем, что тексты газет являются сегодня одной из самых распространeнных форм бытования языка. В современном газетном дискурсе усилилась активная оценочно-воздействующая направленность. Сегодня можно говорить об особой прагматической интенсивности газетного текста, его насыщенности. Одной из смысловых составляющих интенсивности является семантика невыразимого, которая и вызывает интерес. Цель статьи – выявление бытования семантики невыразимого в современных газетных текстах. Принимая во внимание богатый потенциал газетного дискурса как сферы, продуцирующей всe новые приeмы реализации категории образности, полагаем, что изучение семантических и функциональных свойств невыразимого является актуальной научной задачей. В современном газетном дискурсе авторами используются понятия «невыразимое» и его лексико-семантическая группа как критерий невозможности выразить словами. В текстах газет семантика невыразимого выражается широким набором лексических средств: это имена прилагательные с приставкой, передающей семантику отрицания, лишения (невыразимый, непередаваемый, неописуемый, неизречeнный и др.), их дериваты: непередаваемо, несказанно, неописуемо, неизъяснимо и др.; глагольные словосочетания: невозможно выразить (передать, сказать); оксюморон: выразить невыразимое; фразеологические единицы: нет слов (чтобы выразить). Наиболее частотны в современном газетном дискурсе в плане передачи значения невыразимого прилагательные невыразимый, непередаваемый и их дериваты, среднечастотны – наречия, грамматические и лексические варианты фразеологизмов-предложений нет слов, не находить слов, словами не передать и глагольные перифразы с отрицанием не могу выразить, не могу передать словами, сказать не могу.
The article studies the lexical means of the semantics of the inexpressible. The inexpressible is a functional and semantic category of the Russian language which serves to convey the impossibility of expressing an object of speech by speech participants. The dynamic development of the printed media has a huge impact on the production and distribution of newspaper texts. The relevance of our research lies in the fact that newspaper texts are contemporarily one of the most common forms of language existence. The modern newspaper discourse has been dominated by the evaluative and influencing orientation. Today we can talk about a special pragmatic intensity of newspaper texts and their saturation. One of the semantic components of intensity is the semantics of the inexpressible. The purpose of the article is to identify the existence of unspeakable semantics in modern newspaper texts. Taking into account the rich potential of newspaper discourse as a sphere that produces all new methods of implementing the category of imagery, we believe that the study of the semantic and functional properties of the inexpressible is an urgent research objective. In the modern newspaper discourse, authors use the concept of ‘inexpressible’ and its lexical-semantic group as a criterion for the impossibility of expressing things in words. In newspaper texts, the semantics of the inexpressible is expressed by a wide range of lexical means: adjectives with a prefix that conveys the semantics of negation, deprivation (inexpressible, indescribable, indescribable, unspeakable, etc.) and their derivatives, such as indescribable, unspeakable, indescribable, inexplicable, etc.; verb phrases that it is impossible to express (convey say); oxymoron as an expression of the inexpressible; phraseological units with no words (to express). The most frequent in the modern newspaper discourse, in terms of the transfer values of unspeakable, are the adjectives unspeakable, indescribable and their derivatives, mid-adverb, grammatical and lexical variants of phraseological units-sentences, such as no words, not finding words, words cannot describe and paraphrased verbs with negation, such a can’t tell, not words, I cannot say.
Źródło:: Acta Universitatis Lodziensis. Folia Linguistica Rossica; 2020, 19; 113-123
1731-8025
2353-9623
Pojawia się w:: Acta Universitatis Lodziensis. Folia Linguistica Rossica
Dostawca treści:: Biblioteka Nauki

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Tytuł:: Про лінгвістичні показники взаємодії мова – культура на прикладі аналізу польсько- українського пограниччя XV-XIXст.
Autorzy:: Маtsyuk, Halyna
Powiązania:: https://bibliotekanauki.pl/articles/1788625.pdf
Data publikacji:: 2020-08-31
Wydawca:: Uniwersytet Warszawski. Wydawnictwa Uniwersytetu Warszawskiego
Tematy:: culture of the Polish-Ukrainian border territories
onymic systems
linguistic knowledge
linguistic markers of language and culture interaction
культура польсько-українського пограниччя
ономастичні системи
лінгвістичне знання
лінгвістичні маркери взаємодії мови та культури.
Opis:: The article is devoted to the formation of a linguistic interpretation of the interaction of language and culture of the Polish-Ukrainian border territories. The material for the analysis includes nomic systems of Ukrainian and Polish languages, which are considered as a cultural product of interpersonal and interethnic communication and an element of the language system, as well as invariant scientifi c theory created in the works of Polish onomastics (according to key theoretical concepts, tradition of analysis, and continuity in linguistic knowledge). The analysis performed in the article allows us to single out the linguistic indicators of the interaction of language and culture typical for the subject fi eld of sociolinguistics. These are connections and concepts: language-territory, language-social strata, language-gender, language-ethnicity, social functions of the Polish language, and non-standardized spelling systems. Linguistic indicators reveal the peculiar mechanisms of the border in the historical memory and collective consciousness, marking the role of languages in these areas as a factor of space and cultural marker and bringing us closer to understanding the social relations of native speakers in the fifteenth-nineteenth centuries.
Źródło:: Studia Ucrainica Varsoviensia; 2020, 8; 129-148
2299-7237
Pojawia się w:: Studia Ucrainica Varsoviensia
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 4.

Tytuł:: Някои особени лексеми в старобългарския превод на Иполитовото тълкувание на Книга на пророк Даниил
Autorzy:: Илиев [Iliev], Иван [Ivan] И. [I.]
Powiązania:: https://bibliotekanauki.pl/articles/677380.pdf
Data publikacji:: 2016
Wydawca:: Polska Akademia Nauk. Instytut Slawistyki PAN
Tematy:: Book of Daniel
Hippolytus of Rome
commentary
Old Bulgarian translation
lexical markers
Opis:: Some specific lexemes in the Old Bulgarian translation of Hippolytus of Rome’s Commentaries on the Book of Prophet DanielThe object of the current research is Talkovanie na Kniga na propok Daniil – the Slavonic version of the Commentaries on the Book of Prophet Daniel (Commentarii in Danielem, CPG 1873) by Hippolytus of Rome (c. 170–235), the earliest and most profound commentaries on this Old Testament book. They were written round 204 and their translation into Old Bulgarian can be counted among the earliest works of Bulgarian literature. The time of the Commentaries’ translation is under discussion, its dating ranging from the last decades of the ninth to the middle of the tenth century. Some linguistic facts of the Commentaries have sporadically been compared with the partial translation of the Book of the Prophet Daniel, included in the Prophetologion. Also, some comparisons have been made between the Slavonic translation of the Commentaries and the so-called Talkovni proroci – a translation of Old Testament books of prophets with commentaries. The analysis is based on a 1519 manuscript of the Commentaries (No. 486 from the Volokolamsk Collection, Russian State Library, Moscow), which follows the tradition of the earlier copies and most profoundly keeps the content of the Commentaries. In addition to morphological particularities, in the text there are many lexical idiosyncrasies, which can facilitate the dating and localization of the translation. Among these lexical markers can be singled out which show more interesting data. Many lexemes can be found which are particular to the early written codices and testify to the antiquity of the translation. For instance, some specific lexemes match with words, used in the Codex Suprasliensis and the First Miscellany of Tsar Simeon (Izbornik of 1073), which shows that the Commentaries are one of the earliest translated works of the Old Bulgarian literature. Wybrane charakterystyczne leksemy w starobułgarskim przekładzie Komentarzy do Księgi Proroka Daniela Hipolita RzymskiegoPrzedmiotem artykułu jest słowiańska wersja Komentarzy do Księgi Proroka Daniela (Commentarii in Danielem, CPG 1873) autorstwa Hipolita Rzymskiego (ok. 170–235), najwcześniejszych i najbardziej wnikliwych komentarzy do tej starotestamentowej księgi. Zostały one napisane około 204 roku, a ich przekład na język starobułgarski sytuuje się wśród najstarszych dzieł literatury bułgarskiej. Wciąż dyskutowany jest czas jego powstania: od ostatnich dekad wieku IX do połowy X. Niektóre fakty językowe związane z Komentarzami były sporadycznie porównywane z częściowym przekładem Księgi Proroka Daniela, zawartym w paremejniku. Porównywano także słowiański przekład Komentarzy z tak zwaną Księgą Proroków Starego Testamentu wraz z komentarzami. Artykuł koncentruje się na rękopisie z 1519 roku (Nr 486 w Zbiorze z Biblioteki Wołokołamska, Rosyjska Biblioteka Państwowa, Moskwa), który śledzi tradycję wcześniejszych kopii i najdokładniej zachowuje zawartość Komentarzy. Oprócz ich morfologicznej specyfiki w tekście znajduje się wiele cech leksykalnych, które pomagają określić datę i miejsce powstania przekładu. Wśród nich znajdują się markery leksykalne, które zasługują na uwagę, gdyż prowadzą do ciekawych odkryć. Wiele leksemów zawartych w tekście odnosi się do wczesnych kodeksów i świadczy o starożytności przekładu. Niektóre charakterystyczne leksemy łączą się ze słowami użytymi w Codex Suprasliensis i Pierwszym Zborniku Cara Symeona (Izbornik, 1073 rok), co dowodzi, że Komentarze są jedną z najwcześniejszych przetłumaczonych prac w obrębie literatury starobułgarskiej.
Źródło:: Slavia Meridionalis; 2016, 16
1233-6173
2392-2400
Pojawia się w:: Slavia Meridionalis
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 5.

Tytuł:: Ситуация как фактор стиля
Situation as a Style Factor
Autorzy:: ГОНЧАРОВА, ЕВГЕНИЯ A.
Powiązania:: https://bibliotekanauki.pl/articles/953946.pdf
Data publikacji:: 2010
Wydawca:: Uniwersytet Opolski
Tematy:: style
situation
text formulating modus
speech competence
stylistic information
extralinguistic factors
‘external’ situation
‘internal’speech-contextual style determinant
situational style factors
linguostylistic markers of situation
Opis:: There is no unanimous point of view concerning the organic relationship between ‘style’ and ‘situation’, mainly because o f different definitions and interpretations of the concept o f ‘style’. As a quality of an integral text, style presents a text formulating modus, which characterizes new textual qualities that appear as optional to the basic necessary criteria o f textuality (e.g. integrality, coherence, etc.) as a result o f altering the ‘situation’ of making and perceiving the text. Making a ‘style’ means formulating that kind of a text structure which would accommodate to the ‘situation’ of presenting (new) information to the communication partners. As a subject o f a philological description ‘situation’ can be interpreted both in the broad and in the narrow sense. It can take into account extralinguistic factors of making and perce ■ mg the text, which influence the style as well as proper linguistic mechanisms that define the nature of stylistic information of a particular text. In the textual structure one can differentiate a certain system of relations between separate situational style factors as well as their linguostylistic markers. The character of such hierarchy may vary in different text classes and types. This proves the fact that both the ‘situation’ as a (text) style factor and the elements, which function as linguistic markers of stylistic information, are o f a gradient character.
Źródło:: Stylistyka; 2010, 19; 7-22
1230-2287
2545-1669
Pojawia się w:: Stylistyka
Dostawca treści:: Biblioteka Nauki

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Tytuł:: Advanced oxidation protein products and inflammatory markers in liver cirrhosis: a comparison between alcohol-related and HCV-related cirrhosis
Autorzy:: Zuwała-Jagiełło, Jolanta
Pazgan-Simon, Monika
Simon, Krzysztof
Warwas, Maria
Powiązania:: https://bibliotekanauki.pl/articles/1039949.pdf
Data publikacji:: 2011
Wydawca:: Polskie Towarzystwo Biochemiczne
Tematy:: advanced oxidation protein products
cirrhosis
inflammatory markers
Opis:: Advanced oxidation protein products (AOPPs) are protein markers of oxidative stress with pro-inflammatory properties that accumulated in liver cirrhosis. In the present study, we investigated the association between chronic inflammatory response triggered by AOPPs and the severity of liver disease as assessed by the Child-Pugh score. Plasma concentrations of AOPPs and inflammatory markers such as C-reactive protein, tumor necrosis factor-α, and interleukin-6 were measured in 41 patients with HCV-related cirrhosis, 43 patients with alcohol-related liver cirrhosis (ALC), and in 30 age and sex matched controls. In comparison with controls, AOPPs were increased in HCV-related compensated (Child-Pugh A) and decompensated (Child-Pugh B-C) cirrhosis and in alcohol-related compensated cirrhosis. AOPPs level positively correlated with Child-Pugh score in alcohol-related cirrhosis but not in HCV-related cirrhosis and the correlation with the indices of chronic inflammation was stronger in ALC. In turn, AOPPs in HCV-related cirrhosis was related to inflammation to a lesser extent, but a significant correlation with antioxidant defense could be noted. In summary, liver cirrhosis was associated with increased formation of AOPPs, which differed between alcohol-related and HCV-related cirrhosis with respect to the relationship between AOPPs and antioxidant defense, stage of liver cirrhosis, and inflammatory response. The significant correlation between AOPPs accumulation and indices of chronic inflammation, more specifically TNF-α, suggests that oxidative stress may be a mediator of chronic inflammatory state in the early stage of alcohol-related cirrhosis.
Źródło:: Acta Biochimica Polonica; 2011, 58, 1; 59-65
0001-527X
Pojawia się w:: Acta Biochimica Polonica
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 7.

Tytuł:: Selekcja genomowa w hodowli drzew leśnych - podstawowe założenia, problemy i perspektywy
Genomic selection in forest tree breeding - basic principles, problems and future prospects
Autorzy:: Żukowska, W.B.
Wójkiewicz, B.
Lewandowski, A.
Powiązania:: https://bibliotekanauki.pl/articles/978931.pdf
Data publikacji:: 2020
Wydawca:: Polskie Towarzystwo Leśne
Tematy:: breeding value
genetic gain
genetic markers
marker−assisted selection
quantitative trait locus
single
nucleotide polymorphism
Opis:: All tree breeders cope with the same challenge of the very long time interval of a single breeding cycle. What is more, trees are long−lived, with desirable breeding traits expressing late during their life cycle. Increasing problems with climate change, globalization or economic growth have forced us to accelerate tree breeding and improve selection precision, both of which can be achieved by genomic selection (GS). The idea of GS was introduced nearly 20 years ago as an extension of marker−assisted selection (MAS) in order to advance breeding technologies using genetic markers. Unlike MAS, which exploits only a set of marker−trait associations, GS relies on a high number of genetic markers that are spread throughout the entire length of the genome. All markers effects are assessed simultaneously in order to build a precise model that allows prediction of genetic estimated breeding value of a particular individual using genetic data only. GS has already revolutionized dairy cattle breeding resulting in remarkable improvements across multiple traits and is becoming more and more common in crop production. We now know that genetic architecture of quantitative traits is complex, but recent advances in genomics have made it possible to deal with this problem in an unprecedented way. There are certain concerns regarding GS in forest tree species that include genotype−environment (G×E) interaction and the usefulness of the predictive model built up by GS in the next generation of trees. Nevertheless, experimental results obtained so far have shown that the genetic gain per unit time as well as selection precision can be substantially increased. Here we present the basic principles of GS for forest tree species, giving examples of studies carried out so far and discussing problems and future possibilities that GS may soon open up for forest tree breeders.
Źródło:: Sylwan; 2020, 164, 05; 384-391
0039-7660
Pojawia się w:: Sylwan
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 8.

Tytuł:: Wykorzystanie biotechnologii przez polską hodowlę roślin
Exploitation of biotechnology by Polish plant breeding
Autorzy:: Zimnoch-Guzowska, Ewa
Gołębiewska, Małgorzata
Powiązania:: https://bibliotekanauki.pl/articles/2198015.pdf
Data publikacji:: 2011-03-31
Wydawca:: Instytut Hodowli i Aklimatyzacji Roślin
Tematy:: kierunki hodowli
ograniczenia postępu hodowlanego
wykorzystanie markerów molekularnych
hodowla wstępna
usługi biotechnologiczne
breeding directions
difficulties in breeding
use of molecular markers
pre-breeding
biotechnological services
Opis:: W ramach koordynacji projektu badawczego zamawianego PBZ-MNiSW-2/3/2006 pt. „Nowe metody genetyki molekularnej i genomiki służące doskonaleniu odmian roślin uprawnych” przeprowadzono badania ankietowe wśród krajowych ośrodków hodowli roślin na temat wykorzystania biotechnologii w procesie hodowlanym roślin uprawnych. W badaniach wzięło udział 18 krajowych ośrodków hodowli roślin. Ankieta obejmowała 14 rozbudowanych pytań, ukazujących obecny stan wykorzystania biotechnologii w hodowli twórczej, trudności w uzyskaniu oczekiwanego postępu hodowlanego, znacznie pożądanych kierunków hodowli w poszczególnych gatunkach, obecne i przyszłe zastosowanie markerów molekularnych, zainteresowanie firm hodowlanych w szkoleniu własnego personelu, celowości prowadzenia programu hodowli wstępnej przez wyspecjalizowane ośrodki oraz korzystania z usług biotechnologicznych oferowanych hodowcom.
Survey on application of biotechnology in the breeding process of cultivated plants was organized in the frame of coordination of the PBZ-MNiSW-2/3/2006 project entitled: “New methods of molecular genetics and genomics served to variety improvement in cultivated plants”. All of the eighteen invited domestic breeding centers took part in the survey. Fourteen extended questions were focused on current status of biotechnology application to plant breeding, difficulties in achieving expected breeding progress, importance of desired directions in breeding of respective plant species, use of molecular markers — currently and in the future, interest of breeding companies in training of their own staff, necessity of pre-breeding program realization by specialized centers and use of biotechnological services offered to breeders.
Źródło:: Biuletyn Instytutu Hodowli i Aklimatyzacji Roślin; 2011, 259; 121-129
0373-7837
2657-8913
Pojawia się w:: Biuletyn Instytutu Hodowli i Aklimatyzacji Roślin
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 9.

Tytuł:: The concentration of urea in hemolymph as a marker of health in Lissachatina fulica and Cornu aspersum edible snails – a preliminary study
Autorzy:: Ziętek, J.
Guz, L.
Wójcik, A.
Winiarczyk, S.
Adaszek, Ł.
Powiązania:: https://bibliotekanauki.pl/articles/2087559.pdf
Data publikacji:: 2019
Wydawca:: Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:: Lissachatina fulica
Cornu aspersum
hemolymph
urea
markers
Źródło:: Polish Journal of Veterinary Sciences; 2019, 2; 259-262
1505-1773
Pojawia się w:: Polish Journal of Veterinary Sciences
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 10.

Tytuł:: The dynamics of biochemical markers of enzymoemia and middle-weight molecules in the early post-traumatic period of brain injury
Autorzy:: Ziablitsev, S. V.
Elskyy, V. N.
Pischulina, S. V.
Strelchenko, U. I.
Antonov, E. V.
Sudilovskaya, U. L.
Khudoley, S. A.
Powiązania:: https://bibliotekanauki.pl/articles/1032378.pdf
Data publikacji:: 2014
Wydawca:: Uniwersytet Kazimierza Wielkiego w Bydgoszczy
Tematy:: brain injury
biochemical markers
enzymoemia
middle-weight molecules
Opis:: In the experimental model of brain injury (BI) markers of enzymoemia (aminotransferases ALT and AST, alkaline and acid phosphatase (AlP and AcP), cathepsin D (CD)) and middle-weight molecules (MWM) were estimated. 3 hours after trauma there were increase of all enzymes that evidences about damage of cytoplasmic (ALT, AST, AlF) and lysosomal membranes (AcP, CD). During period of observation different dynamics of enzymatic changes occurred: plateau phase for ALT and CD and progressive increase of concentration with the maximum on the 5th day of the experiment for AlP and AcP. Increase of the level of MWM displayed the development of endogenous intoxication in the post-traumatic period. Relation between particular components of MWM was studied. It was shown that primary accumulation of nucleotide fraction and aromatic peptides is adverse factor of the course of post-traumatic period, development of endotoxicosis, and multiorgan failure.
Źródło:: Journal of Health Sciences; 2014, 4, 1; 297-302
1429-9623
Pojawia się w:: Journal of Health Sciences
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 11.

Tytuł:: Fast and cheap identification of elite aspen clones in the North-West of Russia using ISSR markers
Autorzy:: Zhigunov, Anatoly V.
Shabunin, Dmitrii A.
Butenko, Olesia Yu.
Lebedeva, Marina V.
Powiązania:: https://bibliotekanauki.pl/articles/2045732.pdf
Data publikacji:: 2018
Wydawca:: Instytut Badawczy Leśnictwa
Tematy:: aspen
elite clones
molecular markers
ISSR
clonal plantations
Opis:: In 2001–2006, several experimental aspen plantations were established in the North-West of Russia (Leningrad region). Three in vitro propagated elite aspen (Populus tremula L.) clones from the Kostroma Forest Research Station were used as the planting stock for plantations. The planting plans of some experimental plantations were lost, which made it impossible to identify the genetic lineages. 13-years old unknown aspen clones demonstrated prominent growth rates, and reliably overtook natural aspen coppice. ISSR markers were used for fast and cheap restoring of the missing planting plan of the experimental aspen plantation under study; as a result, progenies of three elite aspen clones were recognized. The best fast-growing and stem rot resistant aspen clones was identified and called “Kostroma”.
Źródło:: Folia Forestalia Polonica. Series A . Forestry; 2018, 60, 4; 207-213
0071-6677
Pojawia się w:: Folia Forestalia Polonica. Series A . Forestry
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 12.

Tytuł:: Occupational daily walking steps have inverse relationship with papillary thyroid cancer risk and progression: a retrospective analysis
Autorzy:: Zhang, Chunling
Zhang, Li
Su, Yan
Xiang, Lei
Zhang, Qin
Zhang, Chunhong
Huan, Qin
Powiązania:: https://bibliotekanauki.pl/articles/28761990.pdf
Data publikacji:: 2024-03-05
Wydawca:: Instytut Medycyny Pracy im. prof. dra Jerzego Nofera w Łodzi
Tematy:: biochemical markers
office workers
construction workers
papillary thyroid cancer
daily step counts
PTC stages
Opis:: Objectives Investigate the impact of daily occupational walking steps on the progression of papillary thyroid cancer (PTC), a topic hitherto underresearched. Material and Methods The authors analyzed the data from 800 individuals with PTC across stages 0–IV. Participants were evenly divided into 2 distinct occupational groups: office workers and construction workers (N = 400 each). Data included comprehensive records of daily walking steps, demographic information, and clinical indicators. Pearson’s correlation coefficients or analysis of variance (ANOVA) were employed to assess the linkage between daily walking steps and PTC risk and stage, as well as associated biochemical markers. Results The analysis revealed a significant inverse relationship between daily walking steps and PTC risk. A higher frequency of daily steps was associated with reduced chances of PTC onset and a lower diagnostic stage of the disease. This protective effect of physical activity was particularly pronounced in the construction worker cohort. Subsequent evaluations showed that construction workers who consistently logged higher daily steps had markedly lower levels of thyroid-stimulating hormone (TSH), free triiodothyronine, free thyroxine, thyroid peroxidase antibody, thyroglobulin antibody, and thyroglobulin (Tg). Notably, daily walking steps exhibited a strong inverse correlation with body mass index (BMI), age, PTC volumes, and levels of TSH and Tg across both occupational groups (ρ < –0.37). The increase in daily steps was associated with the reduction in PTC stages (p < 0.001). Conclusions The research underscores the potential benefits of increased daily walking steps, suggesting that they may play a protective role in reducing PTC risk and moderating its progression.
Źródło:: International Journal of Occupational Medicine and Environmental Health; 2024, 37, 1; 58-71
1232-1087
1896-494X
Pojawia się w:: International Journal of Occupational Medicine and Environmental Health
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 13.

Tytuł:: Cytochrome P4502C9 genotype in Southeast Anatolia and possible relation with some serum tumour markers and cytokines.
Autorzy:: Yılmaz, Necat
Erbağcı, Ayşe
Aynacioğlu, A
Powiązania:: https://bibliotekanauki.pl/articles/1044109.pdf
Data publikacji:: 2001
Wydawca:: Polskie Towarzystwo Biochemiczne
Tematy:: CYP2C9 polymorphism
Anatolia
cytokines
tumour markers
Opis:: Substrates for CYP2C9 include fluoxetine, phenytoin, warfarin, losartam and numerous nonsteroidal anti-inflammatory drugs. Polymorphisms in the coding region of the CYP2C9 gene produce variants at amino-acid residues 144 Arg/Cys and 359 Ile/Leu of the CYP2C9 protein. Individuals homozygous for Leu359 have markedly diminished metabolic capacities for most CYP2C9 substrates, the frequency of this allele is, however, rather low. Consistently with the modulation of enzyme activity by genetic and other factors, wide interindividual variability occurs in the elimination and/or dosage requirements of prototypic CYP2C9 substrates. The polymorphic enzyme CYP2C9 takes part in the metabolism of alkylating agents and polycyclic aromatic hydrocarbons like benzo(a)pyrene, a carcinogen present in tobacco smoke. Although the impact of impaired enzyme activity in metabolism of carcinogens and procarcinogens has not been fully defined, an association of CYP2C9 variant alleles to DNA adduct levels in lung tissues as well as to lung cancer risk have been reported. In this study 64 healthy subjects (44M/22F) were analysed for CYP2C9 genotype with PCR-RFLP and for serum carcinoembryonic antigen (CEA), α-fetoprotein (AFP), CA 19-9, CA 15-3, ferritin, IL-6, IL-8 concentrations by chemiluminescence or electrochemiluminescence methods. CYP2C9*1 was found to be the most prevalent allele and CYP2C9*1/CYP2C9*1 was the most frequent genotype represented in 64% of the population in southeastern Anatolia (Gaziantep). Although slight differences in serum tumour marker and cytokine concentrations were observed for CYP2C9 genotypes the differences were statistically insignificant (P >0.05). This could be due to the complexity of the role of CYP2C9 in benzo(a)pyrene metabolism as well as from other contributing factors like interindividual variability of diverse enzymes participating in the same metabolic pathway, unequal expression of the variant alleles and differences in exposure to carcinogens. However, determination of CYP2C9 phenotypes in a larger group of subjects might clarify these slight differences.
Źródło:: Acta Biochimica Polonica; 2001, 48, 3; 775-782
0001-527X
Pojawia się w:: Acta Biochimica Polonica
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 14.

Tytuł:: Multiplexed Immunobead-Based Cytokine Profiling in patients with ovarian cancer
Autorzy:: Wyciszkiewicz, Aleksandra
Lach, Michał
Kalinowska, Alicja
Michalak, Sławomir
Nowakowski, Błażej
Powiązania:: https://bibliotekanauki.pl/articles/1890964.pdf
Data publikacji:: 2021-12-02
Wydawca:: Gdański Uniwersytet Medyczny
Tematy:: ovarian cancer
cytokines
metalloproteinases
inflammation markers
endometriosis
Opis:: Due to late diagnosis, ovarian cancer is the most deadly gynecologic malignancy. Inflammation is one of the risk factors of ovarian cancer and the inflammatory response implicates all stages of tumorigenesis. The purpose of this study was to analyze the concentration of molecules, which can take part in malignant processes. We analyzed patients with ovarian cancer, with endometriosis and healthy controls. Thirty-seven analytes were measured in serum using BioPlex Pro Human Inflammation Panel. We were able to detect 28 of the proteins among the studied groups. We found a significant increase in 22 of the tested molecules (BAFF, Chitinase3-like 1, IFN-alpha2, IFN-beta, IFN-gamma, IFN-lambda2, IFN-lambda1, gp130, IL-2, IL-12 (p40), IL-11, IL-32, IL-35, MMP3, Osteocalcin, Pantraxin-3, sCD163, TNFRSF8, sIL-6Ralpha, STNF-R1, STNF-R2, and TSLP) in the ovarian cancer group in comparison to the healthy controls. Two of them (IL-20, MMP1) did not show significant differences between groups. Moreover, we identified decreased concentrations of APRIL and osteopontin in ovarian cancer vs. healthy controls. While this study is a preliminary report, we hope this will encourage a further use of multiplex analysis in ovarian cancer biomarker research.
Źródło:: European Journal of Translational and Clinical Medicine; 2021, 4, 2; 31-43
2657-3148
2657-3156
Pojawia się w:: European Journal of Translational and Clinical Medicine
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 15.

Tytuł:: Das Schwache Verb und seine Exponenten vom Mittel- bis zum Neuhochdeutschen
Autorzy:: Woźnicka, Marta
Powiązania:: https://bibliotekanauki.pl/articles/2076083.pdf
Data publikacji:: 2015
Wydawca:: Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:: verb
verb components
inflection markers
tense markers
mode markers
Opis:: In the article a new method of determining the so-called markers of inflexion, tense and mode of synthetic forms within the group of weak verbs was presented, and the whole concept is based on the innovative model of a linguistic analysis developed by Jozef Darski (1987; 22004). The model mentioned above is adapted for diachronic analysis, which allows to depict the development of the markers enumerated above from mid- to new-high-German.
Źródło:: Kwartalnik Neofilologiczny; 2015, 4; 703-713
0023-5911
Pojawia się w:: Kwartalnik Neofilologiczny
Dostawca treści:: Biblioteka Nauki

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