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    Wyświetlanie 1-15 z 15
    Tytuł:
    Total Laryngectomy for Treatment of T4 Laryngeal Cancer: Trends and Survival Outcomes
    Autorzy:
    Badwal, Jaspreet Singh
    Powiązania:
    https://bibliotekanauki.pl/articles/1391950.pdf
    Data publikacji:
    2019
    Wydawca:
    Index Copernicus International
    Tematy:
    Total laryngectomy
    laryngeal cancer
    T4 laryngeal cancer
    Opis:
    Introduction: Management of advanced laryngeal cancer has shown fluctuating trends during the last few decades. Though many extensive reports are available in the literature regarding survival outcomes for advanced laryngeal cancer, there is a paucity of elaborate systematic reviews giving a complete picture of facts and figures. The present analysis brings to attention the most relevant data in a focused and up to date format, for simpler interpretation of evidence-based inference. Objective: To present the trends in the treatment of T4 laryngeal cancer over the past few decades and analyze survival outcomes for different treatment modalities in the management of T4 laryngeal cancer by way of systematic review. Methods : An electronic search was conducted using the terms “total laryngectomy”, “T4 laryngeal cancer”, “survival outcomes” in combination with the following search strategy : Search block Laryngeal cancer - "Laryngeal Neoplasms"[Mesh] OR ((Laryngeal[tiab] OR larynx[tiab] OR "Larynx"[Mesh]) AND (“Neoplasms”[Mesh] OR neoplasm* [tiab] OR tumor* [tiab] OR tumour* [tiab] OR cancer* [tiab] OR malignancy* [tiab] OR carcinoma* [tiab] OR neoplasm* [tiab] OR oncology* [tiab])); Search block Total laryngectomy - "Laryngectomy"[Mesh] OR total laryngectomy*[tiab] OR total laryngopharyngectomy*[tiab] OR total pharyngolaryngectomy*[tiab]; Search block T4 - t4[tiab]. Clinical studies were retrieved from the electronic databases of PubMed, EMBASE, SCOPUS and Cochrane Library. 304 articles had been published till June 2017, which included prospective studies, randomized controlled trials, retrospective studies, and smaller descriptive studies. References of the selected studies were further searched for relevant articles. Apart from this, a search was conducted on Google Scholar to obtain related articles. Results: Numerous studies, as mentioned in this review, provide authentic evidence in relation to the efficacy and outcome of surgical treatment for T4 laryngeal cancer. To address the problem of heterogeneity with regards to patient selection, numerous reports pertaining to T4 patients exclusively have been included. Conclusion: Total laryngectomy remains the gold standard for management of T4a laryngeal cancer. After the unparalleled oncological outcomes of more than a century, the technique has stood the test of time. An exhaustive review of the literature has been presented, discussing the trends in the treatment of advanced laryngeal cancer across different continents. However, it must be specified that the purpose of the study is not to prove one treatment protocol to be superior to the other but to bring out patterns of adherence to protocols and guidelines as suggested by multidisciplinary consensus reports and the consequent outcomes.
    Źródło:
    Polish Journal of Surgery; 2019, 91, 3; 30-37
    0032-373X
    2299-2847
    Pojawia się w:
    Polish Journal of Surgery
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Comparative analysis of the incidence of Oropharyngeal cancer and Laryngeal cancer in the region of south-eastern Poland from 1980 to 2013
    Autorzy:
    Gawełko, Jan
    Cierpiał-Wolan, Marek
    Kawecki, Andrzej
    Podgórska-Bednarz, Justyna
    Powiązania:
    https://bibliotekanauki.pl/articles/454937.pdf
    Data publikacji:
    2017
    Wydawca:
    Uniwersytet Rzeszowski. Wydawnictwo Uniwersytetu Rzeszowskiego
    Tematy:
    oropharyngeal cancer
    laryngeal cancer
    incidence
    Opis:
    Introduction. The incidence of head and neck cancers in Poland demonstrated a general tendency to stabilize in the last two decades. However, a global phenomenon in the change of morbidity structure in terms of the specific anatomical location is observed, which will probably increasingly apply also to Poland. Aim. The aim of the study was to present the changes that have occurred in the structure of the incidence of oropharyngeal cancer in comparison to laryngeal cancer in the period from 1980 to 2013, in the region of south-eastern Poland and the whole country. Material and methods. A retrospective analysis of the incidence due to the head and neck organ cancer in 1980-2013 in the region of south-eastern Poland and the whole country was performed based on demographic data from the Provincial Statistical Office in Rzeszow and Podkarpackie Cancer Register as well as the Department of Epidemiology, Oncology Centre in Warsaw. Results and conclusion. In the last three decades, the percentage of laryngeal cancer incidence in women (13% vs 18%) as well as oropharyngeal cancer (18.2 % vs 21.6%) was lower in Podkarpacie than in Poland overall. The incidence of oropharyngeal cancer in men in Podkarpacie was lower in the analyzed period than in Poland overall, and only in the last 3 years of observation has it reached a value close to the average for the country. The incidence of laryngeal cancer in men showed a dramatic downward trend both in Poland and in the Podkarpacie province, whereby both in terms of incidence rates and standardized rates and percentages – it is far more pronounced in the analyzed province.
    Źródło:
    European Journal of Clinical and Experimental Medicine; 2017, 1; 39-44
    2544-2406
    2544-1361
    Pojawia się w:
    European Journal of Clinical and Experimental Medicine
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Nicotinism and the knowledge of consequences of laryngectomy among university students
    Autorzy:
    Hamerlińska, Agnieszka
    Powiązania:
    https://bibliotekanauki.pl/articles/930320.pdf
    Data publikacji:
    2020-12-15
    Wydawca:
    Uniwersytet im. Adama Mickiewicza w Poznaniu
    Tematy:
    nicotinism
    knowledge
    laryngeal cancer
    health
    Opis:
    Nicotine addiction is currently one of the most serious health and social problems worldwide, which contributes to the development of numerous diseases, including, above all, laryngeal cancer, which may lead to laryngectomy. The consequences of losing one’s larynx are irreversible. The objective of the study presented in this paper was to describe the knowledge of the consequences of radical laryngectomy among students pursuing a variety of majors. The study covered 194 people (119 non-smokers and 75 smokers), who took part in diagnostic survey based on a bespoke questionnaire. Based on the study in question, the author determined that the level of knowledge about the consequences of laryngectomy among the majority of students is average to low, while smoking students have an average awareness of these consequences. Moreover, it turned out that age, gender, major and the number of smokers in students’ closest circles do not determine the knowledge about the subject at hand. The results of the study indicate that the anti-smoking public service campaigns addressed to youth should include information about both the risk of diseases and their consequences, which may significantly reduce the quality of life and hinder everyday functioning.
    Źródło:
    Interdyscyplinarne Konteksty Pedagogiki Specjalnej; 2020, 30; 67-87
    2300-391X
    Pojawia się w:
    Interdyscyplinarne Konteksty Pedagogiki Specjalnej
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Surgical voice rehabilitation performed by means of voice prosthesis post laryngectomy
    Autorzy:
    Kamiński, Bartłomiej
    Powiązania:
    https://bibliotekanauki.pl/articles/454923.pdf
    Data publikacji:
    2017
    Wydawca:
    Uniwersytet Rzeszowski. Wydawnictwo Uniwersytetu Rzeszowskiego
    Tematy:
    laryngeal cancer
    voice prosthesis
    tracheoesophageal fistula
    Opis:
    Introduction. In 1972, in Poland, Professor Erwin Mozolewski presented a pioneering thesis concerning the creation of intubated voice fistula in a group of 24 patients. It was undoubtedly the prototype of today’s voice prosthesis. Materials and method. The study involved 33 men after total laryngectomy due to advanced squamous cell carcinoma, treated in the Otolaryngology Ward of the District Hospital in Skarżysko-Kamienna between the years 2012–2017, who were implanted with a voice prosthesis Provox II and Provox Vega. Results. During the analyzed period, 127 voice prosthesis were replaced in 33 patients. This paper focuses on complications connected with the implantation of voice prosthesis. The most common reason for replacement of a voice prosthesis was fluid leakage through the voice prosthesis channel – 95 cases. Spontaneous prolapse of the voice prosthesis occurred in 11 patients, and after re-insertion of the prosthesis, the correct fistula voice was obtained. The voice prosthesis was replaced due to difficulty in creating the prosthetic speech in 8 patients. A much more serious complication is the occurrence of leakage around the voice prosthesis. In the examined group, leakage around the prosthesis occurred in 5 patients. An inflammatory plaque was formed around the prosthesis, which was removed in case of significant prosthetic cover or at the request of an alarmed patient – in 4 patients. The prosthesis protruded and rotated in the trachea and hung on a fragment of mucous membrane of the trachea in 1 patient.
    Źródło:
    European Journal of Clinical and Experimental Medicine; 2017, 4; 338-341
    2544-2406
    2544-1361
    Pojawia się w:
    European Journal of Clinical and Experimental Medicine
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Treatment of advanced laryngeal and laryngeal throat cancer - review of literature and own experience
    Autorzy:
    Krawczyk, Przemysław
    Osuch-Wójcikiewicz, Ewa
    Majszyk, Daniel
    Bruzgielewicz, Antoni
    Niemczyk, Kazimierz
    Powiązania:
    https://bibliotekanauki.pl/articles/1399901.pdf
    Data publikacji:
    2018
    Wydawca:
    Index Copernicus International
    Tematy:
    radiotherapy
    histopathology
    dyspnea
    laryngeal cancer
    monoclonal antibodies
    Opis:
    As many as 70-85% of laryngeal and laryngopharyngeal cancers are diagnosed at a high staging, comprising a great diagnostic and therapeutic challenge with influence on poor treatment results. Patients with advanced lesions, that is, stages III and IV, qualify for primary surgical treatment or chemoradiotherapy, depending on the clinical stage, poor prognostic factors and preferences of the patient. Reliable qualifications standards for treatment that would allow to establish homogenous therapeutic recommendations and improvement of treatment results in the group of patients have not yet been developed.
    Źródło:
    Polski Przegląd Otorynolaryngologiczny; 2018, 7, 2; 25-30
    2084-5308
    2300-7338
    Pojawia się w:
    Polski Przegląd Otorynolaryngologiczny
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    The value of pedigrees and clinical assessment in identification of a high risk cancer group – our experience
    Autorzy:
    Jaworowska, Ewa
    Powiązania:
    https://bibliotekanauki.pl/articles/1400526.pdf
    Data publikacji:
    2016
    Wydawca:
    Index Copernicus International
    Tematy:
    laryngeal cancer
    genetic susceptibility
    risk factors
    pedegrees
    Opis:
    Pedigree and clinical data are still very important diagnostic tool useful in estimation of a high risk of a cancer devel-opment, molecular basis research and also determining optimal screening for a single family. In this study the own experience was presented in identification of the risk of cancer prevalence with different organ location among the first degree relatives of 760 patients with laryngeal cancer.
    Źródło:
    Polski Przegląd Otorynolaryngologiczny; 2016, 5, 2; 51-56
    2084-5308
    2300-7338
    Pojawia się w:
    Polski Przegląd Otorynolaryngologiczny
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Evaluation of surgical treatment outcomes in patients with laryngeal cancer during a 5-year follow-up
    Autorzy:
    Morshed, Kamal
    Lewicki, Marcin
    Bojarczuk, Katarzyna
    Tarasiuk-Staniak, Agnieszka
    Smoleń, Agata
    Powiązania:
    https://bibliotekanauki.pl/articles/552324.pdf
    Data publikacji:
    2016
    Wydawca:
    Stowarzyszenie Przyjaciół Medycyny Rodzinnej i Lekarzy Rodzinnych
    Tematy:
    laryngeal cancer
    surgical treatment
    5-year follow-up.
    Źródło:
    Family Medicine & Primary Care Review; 2016, 3; 302-307
    1734-3402
    Pojawia się w:
    Family Medicine & Primary Care Review
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Gender-related incidence, risk factors exposure and survival rates of laryngeal cancers – the 10-years analysis of trends from one institution
    Autorzy:
    Majszyk, Daniel
    Bruzgielewicz, Antoni
    Osuch-Wójcikiewicz, Ewa
    Rzepakowska, Anna
    Niemczyk, Kazimierz
    Powiązania:
    https://bibliotekanauki.pl/articles/1397790.pdf
    Data publikacji:
    2019
    Wydawca:
    Index Copernicus International
    Tematy:
    laryngeal cancer
    epidemiology
    men and women
    risk factors
    Opis:
    Objectives: The aim of the study was the analysis of the epidemiology of laryngeal cancer over 10 years in relation to known risk factors and to assess the current survival rates in this group of patients. Methods: The data were retrospectively collected from patients’ medical records, then entered in the database using dedicated software and a statistical analysis was performed. Results: 512 subjects - 443 men (86.5%) and 69 women (13.5%) were enrolled into the study. The male-to-female ratio was 6.4:1. There were 97.1% smoking women and 98% smoking men, however the history of more than 20 cigarettes per day smoking admitted 81.1 % of women and 94.6% of men. Heavy alcohol consumption was the case in 14 (20.3%) women and in 307 (69.3%) men. For both the size of heavy alcohol consumption and the size of excessive tobacco use, there was found statistically significant difference between women and men with laryngeal cancer (p<0.05). In the majority of male and female subjects, the tumour was located in the supraglottis/glottis area. Apparently this tumour location was much more common among women, accounting for 60.9% of cases , while in men was confirmed in 39.3% of cases. The stages of the laryngeal cancer were similarly of high advancement for both the men and women - stages III and IV were confirmed in 82.6% of women and in 77.6% of men. The over 5-year survival rate was 39.1% among women and 37.2% among men. Conclusions Contradictory to decreased exposure to risk factors and the shorter period for diagnosis, the higher stages of cancer were observed in women. Although in women the advancement was higher and the majority of cases were located in unfavourable supraglottic area, the survival rates were higher. Key words: laryngeal cancer, epidemiology, men and women, risk factors
    Źródło:
    Polish Journal of Otolaryngology; 2019, 73, 3; 6-10
    0030-6657
    2300-8423
    Pojawia się w:
    Polish Journal of Otolaryngology
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Clinical experience of narrow band imaging (NBI) usage in diagnosis of laryngeal lesions
    Autorzy:
    Popek, Barbara
    Bojanowska-Poźniak, Katarzyna
    Tomasik, Bartłomiej
    Fendler, Wojciech
    Jeruzal-Świątecka, Joanna
    Pietruszewska, Wioletta
    Powiązania:
    https://bibliotekanauki.pl/articles/1397688.pdf
    Data publikacji:
    2019
    Wydawca:
    Index Copernicus International
    Tematy:
    laryngeal cancer
    narrow band imaging
    premalignant laryngeal lesions
    white light endoscopy
    Opis:
    Introduction: One of the most recent methods used in imaging of the larynx is NBI. NBI allows to detect specific patterns of pathological angiogenesis suggestive of premalignant or neoplastic lesions. Aim: The aim of the study was to compare imaging of laryngeal lesions in WLE and NBI in relation to histopathological examination. Material and methods: 333 patients with laryngeal lesions underwent endoscopic evaluation in WLE and NBI. Sensitivity, specificity, PPV, NPV for both methods were calculated. The diagnostic value for WLE and NBI was evaluated for two assumptions: a positive result indicates (1) severe dysplasia and cancer, or (2) only cancer. Results: Sensitivity, specificity, PPV, NPV for the first assumption were, respectively for white light compared to NBI: 95.4% vs 98.5%; 84.2% vs 98.5%; 79.6% vs 97.7% and 96.6% vs 99.0%. The values for the second assumption were: 97.4% vs 100%; 79.3% vs 93.5%; 72.6% vs 89.4% and 98.2% vs 100.0%. Higher sensitivity was observed for the second assumption, while higher specificity was recorded for the first assumption. Specificity was significantly higher for NBI than for WLE (p < 0.001). Conclusions: NBI allows to detect and differentiate laryngeal lesions, which are invisible in WLE. Endoscopic examination, especially in NBI mode, is non-invasive, repeatable and remains a useful tool in the daily practice and diagnosis of patients with pathological lesions in the larynx.
    Źródło:
    Polish Journal of Otolaryngology; 2019, 73, 6; 18-23
    0030-6657
    2300-8423
    Pojawia się w:
    Polish Journal of Otolaryngology
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Functional Results after Larynx-Preserving Treatment of Laryngeal Cancer. Suggestions for follow-up
    Autorzy:
    Vlčková, Katarína
    Tedla, Miroslav
    Powiązania:
    https://bibliotekanauki.pl/articles/1397828.pdf
    Data publikacji:
    2019
    Wydawca:
    Index Copernicus International
    Tematy:
    dysphagia
    dysphonia
    functional results
    laryngeal cancer
    post-treatment follow-up
    Opis:
    Introduction: Laryngeal cancer and its treatment are associated with both short- and long-term side effects, affecting laryngeal functions and having an impact on the quality of life. Material and methods: Retrospective analysis of the medical records of patients receiving surgical or non-surgical, larynx- -preserving treatment for laryngeal cancer. Results: After termination of the treatment, the highest proportion of patients with bad voice quality was in the glottic carcinoma group (both in early and late phase), with swallowing dysfunction in the transglottic carcinoma group. Compared to the situation before the treatment, the proportion of patients with impaired voice quality (bad voice quality and loss of voice) initially decreased among all groups (except for supraglottic carcinomas), and during the first post-treatment year either increased or did not change. The proportion of patients with no swallowing dysfunction increased in the supraglottic, subglottic and transglottic carcinoma groups. D iscussion: We consider necessary the implementation of a standard pre- and post-treatment monitoring of the voice and swallowing function in the management of patients with laryngeal cancer.
    Źródło:
    Polish Journal of Otolaryngology; 2019, 73, 5; 31-36
    0030-6657
    2300-8423
    Pojawia się w:
    Polish Journal of Otolaryngology
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Pielęgnacja pacjenta z nowotworem krtani, przebywającego w środowisku domowym
    Care of a patient with laryngeal cancer in the home environment
    Autorzy:
    Przystaś, Beata Joanna
    Powiązania:
    https://bibliotekanauki.pl/articles/20217852.pdf
    Data publikacji:
    2021-09-28
    Wydawca:
    Państwowa Akademia Nauk Stosowanych we Włocławku
    Tematy:
    nowotwór krtani
    proces pielęgnowania
    samoopieka
    laryngeal cancer
    care process
    self-care
    Opis:
    Wstęp. Nowotwory krtani to najczęstsze guzy złośliwe głowy, szyi, a także dróg oddechowych. Częściej dotyczą mężczyzn, rzadziej kobiet. Zachorowalność wzrasta po 50-tym roku życia i rośnie z każdą dekadą. Najczęstszą odmianą histopatologiczną jest rak płaskonabłonkowy. Cel. Celem pracy jest analiza zadań pielęgniarki w pielęgnacji pacjenta z nowotworem krtani, przebywającego w środowisku domowym. Prezentacja przypadku. Mężczyzna lat 59 po zabiegu tracheostomii z powodu choroby nowotworowej, przebywający w warunkach domowych, będący pod opieką pielęgniarki poz. Dyskusja. Operacja całkowitego usunięcia krtani stanowi głębokie okaleczenie, które pływa zarówno na zmianę funkcji fizjologicznych, jak również pozbawia chorego możliwości werbalnej komunikacji z otoczeniem, co rzutuje na stan psychiczny i socjalny pacjenta. Wnioski. Przed pielęgniarką w ramach podstawowej opieki zdrowotnej stoją zadania z obszaru wsparcia informacyjnego, instrumentalnego, a także emocjonalnego. Celem nadrzędnym opieki pielęgniarskiej w środowisku domowym chorego onkologicznie jest mobilizowanie jego sił i zasobów do sprawowania samoopieki i samopielęgnacji w stosunku do własnej osoby, oraz asystowanie na różnych etapach przebiegu procesu chorobowego. Słowa kluczowe: nowotwór krtani, proces pielęgnowania, samoopieka.
    Introduction. Laryngeal cancers are the most common malignant tumours of the head, neck, as well as the respiratory tract. They are more likely to affect men, less often women. Morbidity increases after the age of 50 and increases with each decade. The most common histopathological variant is squamous cell carcinoma. The aim. The aim of the work is to analyse the tasks of the nurse in the care of a patient with laryngeal cancer, located in the home environment. A patient case presentation. A man of 59 years after surgery for a tracheostomia due to cancer, staying at home, under the care of a primary health care nurse. Discussion. The operation to completely remove the larynx constitutes a deep mutilation, which affects both the change in physiological functions, as well as deprives the patient of the possibility of verbal communication with the environment, which affects the mental and social state of the patient. Conclusions. Primary health care nurses face tasks in the area of information, instrumental and emotional support. The overarching goal of nursing care in the oncological patient's home environment is to mobilize his forces and resources to self-care and self-care in relation to his own person, and to assist at different stages of the course of the disease process.
    Źródło:
    Innowacje w Pielęgniarstwie i Naukach o Zdrowiu; 2021, 6, 3; 80-89
    2451-1846
    Pojawia się w:
    Innowacje w Pielęgniarstwie i Naukach o Zdrowiu
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Dysphagia among patients after total laryngectomy: diagnostic and therapeutic procedures
    Autorzy:
    Jamróz, Barbara
    Chmielewska-Walczak, Joanna
    Milewska, Magdalna
    Powiązania:
    https://bibliotekanauki.pl/articles/1399294.pdf
    Data publikacji:
    2020
    Wydawca:
    Index Copernicus International
    Tematy:
    cricopharyngeal muscle
    dilation
    dysphagia
    FEES
    laryngeal cancer
    myotomy
    pharyngoesophageal segment
    substitute speech
    total laryngectomy
    videofluoroscopy
    Opis:
    Dysphagia concerns 10–89% patients after total laryngectomy; to a greater extent it regards patients receiving complementary radiotherapy. The disease mechanism is associated with anatomical changes after surgery (typeof surgery) or complications of adjuvant therapy (xerostomia, neuropathy, swelling of tissue, etc.). The above changes lead to: decreased mobility of the lateral walls of the pharynx and tongue retraction, the occurrence of tounge pumping movements, decreased swallowing reflex, weakening of the upper esophageal sphincter opening, contraction of the cricopharyngeal muscle, tissue fibrosis, formation of pharyngeal pseudodiverticulum, etc. As a result: regurgitation of food through the nose and oral cavity, food sticking in middle and lower pharynx, prolongation of bolus transit time. Upon the formation of tracheoesophageal fistula, there may be aspiration of gastric contents. The above changes considerably reduce patients’ quality of life after surgery. The diagnostic protocol includes: medical interview (questionnaires such as EAT 10, SSQ, MDADI, DHI can be helpful), clinical swallowing assessment and instrumental examinations: primarily videofluoroscopy but also endoscopic evaluation of swallowing. Selected cases also require high frequency manometry. The treatment options include: surgical methods (e.g. balloon dilatation of the upper esophageal sphincter, cricopharyngeal myotomy, pharyngeal plexus neurectomy, removal of the pharyngeal pseudodiverticulum), pharmacological treatment or conservative methods (e.g. botulinum toxin injection of the upper esophageal sphincter, speech therapy, nutritional treatment) and supportive methods such as consultation with a psychologist, physiotherapist, clinical dietitian). The selection of a specific treatment method should be preceded by a diagnostic process in which the mechanism of functional disorders related to voice formation and swallowing will be established.
    Źródło:
    Polski Przegląd Otorynolaryngologiczny; 2020, 9, 4; 23-28
    2084-5308
    2300-7338
    Pojawia się w:
    Polski Przegląd Otorynolaryngologiczny
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Proces komunikowania się pacjenta po laryngektomii całkowitej. Studium przypadku
    Communication process of the patient after total laryngectomy: a case study
    Autorzy:
    Ślęzak, Daria
    Powiązania:
    https://bibliotekanauki.pl/articles/28408944.pdf
    Data publikacji:
    2023
    Wydawca:
    Uniwersytet Łódzki. Wydawnictwo Uniwersytetu Łódzkiego
    Tematy:
    komunikowanie się
    mowa
    rak krtani
    mowa zastępcza
    mowa przełykowa
    laryngektomia całkowita
    diagnoza logopedyczna
    communication
    speech
    laryngeal cancer
    replacement speech
    esophageal speech
    total laryngectomy
    Opis:
    W niniejszym artykule przedstawiono kompleksowe omówienie zagadnień związanych z rakiem krtani, jednym z najczęstszych nowotworów złośliwych rejonu głowy i szyi. Omówiona została rola czynników genetycznych, środowiskowych oraz szkodliwego stylu życia w rozwoju tej choroby. Przedstawiono zarówno chirurgiczne, jak i niechirurgiczne metody leczenia raka krtani. Szczególną uwagę poświęcono zabiegowi laryngektomii całkowitej. W dalszej części artykułu omówiono możliwości komunikacji werbalnej i niewerbalnej pacjentów po operacyjnym usunięciu krtani oraz opisano procedurę badawczą i studium przypadku pacjenta po laryngektomii całkowitej.
    This article presents a comprehensive discussion of issues related to laryngeal cancer, one of the most common malignancies of the head and neck region. The author discusses the role of genetic, environmental, and harmful lifestyle factors in the development of this disease. Treatment methods for laryngeal cancer, both surgical and non‑surgical, are presented. Special attention was paid to the procedure of total laryngectomy. The following part of the article discusses the possibilities of verbal and non‑verbal communication and describes non‑verbal communication of patients after surgical removal of the larynx, as well as the research procedure and a case study of a patient after total laryngectomy.
    Źródło:
    Logopaedica Lodziensia; 2023, 7; 215-227
    2544-7238
    2657-4381
    Pojawia się w:
    Logopaedica Lodziensia
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Serum concentration of total sialic acids in patients with primary laryngeal carcinoma
    Poziom całkowitego kwasu sjalowego w surowicy pacjentów z pierwotnym rakiem krtani
    Autorzy:
    Bronikowska, Izabela
    Świętochowska, Elżbieta
    Morawski, Robert
    Ścierski, Wojciech
    Czecior, Eugeniusz
    Powiązania:
    https://bibliotekanauki.pl/articles/27320993.pdf
    Data publikacji:
    2022-11-23
    Wydawca:
    Index Copernicus International
    Tematy:
    markers in laryngeal cancer
    N-acetyl-5-neuraminic acid
    sialic acids
    squamous cell carcinoma of the larynx
    kwas N-acetylo-5-neuraminowy
    kwas sjalowy
    markery raka krtani
    rak płaskonabłonkowy krtani
    Opis:
    Aim: The aim of the study was to evaluate serum concentrations of total sialic acids (TSA) in patients with squamous cell carcinoma of the larynx preoperatively and 4 years postoperatively and to compare the results with the serum concentration of sialic acids in patients with non-neoplastic laryngeal lesions. Material and methods: The study comprised 52 patients with squamous cell carcinoma of the larynx and 25 patients with non-neoplastic laryngeal lesions. Serum TSA concentrations were assessed in all patients preoperatively. 4 years after surgery, serum TSA concentrations were assessed again in 21 patients from the study group in whom recurrence was not detected. Results: Significantly higher serum concentrations of TSA were found in patients with laryngeal cancer compared to the control group (P < 0.05). Changes in TSA concentrations in the study group depended only on cancer grade (G). Significantly higher TSA concentrations were found in G3 patients. Such a relationship was not found for other parameters assessed. Alcohol consumption was the only important factor that affected TSA concentration in the control group. Significantly higher TSA concentrations were found in patients who admitted alcohol abuse. Significantly lower TSA concentrations were observed in patients with laryngeal cancer who were assessed 4 years postoperatively (P < 0.05). Conclusion: Serum concentration of TSA was increased significantly in laryngeal cancer and decreased significantly after several years of successful treatment. Further studies are warranted to assess the possibility of using sialic acids as a marker or target for immunotherapy.
    Cel: Celem pracy była ocena poziomu całkowitego kwasu sjalowego (TSA) w surowicy pacjentów z rakiem płaskonabłonkowym krtani przed leczeniem operacyjnym oraz 4 lata po leczeniu operacyjnym, a także porównanie uzyskanych wyników z poziomami kwasu sjalowego w surowicy pacjentów z nienowotworowymi zmianami w obrębie krtani. Materiał i metody: Badaniem objęto 52 pacjentów z płaskonabłonkowym rakiem krtani oraz 25 chorych z nienowotworowymi zmianami w krtani. U wszystkich pacjentów dokonano pomiaru stężenia TSA w surowicy przed leczeniem chirurgicznym. Po upływie 4 lat od leczenia chirurgicznego dokonano ponownej oceny poziomu TSA w surowicy 21 pacjentów z grupy badanej, u których nie stwierdzono nawrotu choroby. Wyniki: Zaobserwowano istotnie wyższe stężenia TSA w surowicy pacjentów z rakiem krtani, w porównaniu z pacjentami z grupy kontrolnej (p<0,05). Zmiany w stężeniach TSA w grupie badanej zależały jedynie od stopnia złośliwości nowotworu (G). Istotnie wyższe stężenia TSA odnotowano u pacjentów z nowotworami stopnia G3. Nie stwierdzono jednak podobnej zależności dla pozostałych ocenianych parametrów. Jedynym istotnym czynnikiem wpływającym na stężenie TSA było spożywanie alkoholu. Istotnie wyższe stężenia TSA obserwowano u pacjentów przyznających się do nadużywania alkoholu. U pacjentów z rakiem krtani, badanych 4 lata po leczeniu chirurgicznym, stwierdzono znaczne obniżenie stężeń TSA (p <0,05). Wnioski: Stężenie TSA w surowicy ulega znacznemu zwiększeniu w przebiegu raka krtani i znacznie obniża się w ciągu kilku lat od zastosowania skutecznego leczenia. Ocena możliwości wykorzystywania kwasu sjalowego jako markera lub punktu uchwytu immunoterapii wymaga przeprowadzenia dalszych badań.
    Źródło:
    Polish Journal of Otolaryngology; 2023, 77, 2; 12-17
    0030-6657
    2300-8423
    Pojawia się w:
    Polish Journal of Otolaryngology
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Phonatory compensation in patients with larynx cancer after CO2 laser cordectomy
    Autorzy:
    Kosztyła-Hojna, Bożena
    Łuczaj, Jarosław
    Berger, Greta
    Duchnowska, Emilia
    Zdrojkowski, Maciej
    Łobaczuk-Sitnik, Anna
    Biszewska, Jolanta
    Powiązania:
    https://bibliotekanauki.pl/articles/1397494.pdf
    Data publikacji:
    2020
    Wydawca:
    Index Copernicus International
    Tematy:
    cordectomy
    glottis cancer
    high speed digital imaging
    laryngeal compensation
    Opis:
    Introduction: CO2 laser endoscopic cordectomy is the method of laryngeal cancer treatment. The type of cordectomy (I–VI) depends on the extent of the tumor. Endoscopic laser surgery provides more satisfactory phonation conditions in comparison to open surgical procedures. The aim: The aim of the study was to classify phonatory compensation mechanisms after CO2 laser cordectomy using the HSDI. M aterial and methods: The study included 30 men treated and diagnosed at the Department of Otolaryngology and Department of Clinical Phonoaudiology and Logopedics, Medical University of Bialystok. The control included 30 men with no pathological changes in the larynx. Type III, IV and Va CO2 laser cordectomy have been for glottis cancer treatment. Postoperative evaluation has been conducted 6 months after the surgery. HSDI has been used in larynx visualization. R esults: Type I compensation occurs most frequently in patients after type III cordectomy. Advanced glottis cancer, as an indication for type IV and V cordectomy, leads to epiglottic hyperfunction and phonation involving vestibular folds – type II and III compensation. Type IV compensation is most frequent in type IV cordectomy. C onclusions: The type compensation is connected with the extent of glottis resection. In cordectomy including anterior commissure and the part of opposite fold (type Va), supraglottic hyperfunction with the participation of vestibular folds (type II and III compensation) has been recorded. Transmuscular cordectomy (type III) most often resulted in type I compensation. Type III-Va cordectomy caused reduction or absence of MW, decrease in amplitude and aperiodicity of vibrations in HSDI.
    Źródło:
    Polish Journal of Otolaryngology; 2020, 74, 2; 31-35
    0030-6657
    2300-8423
    Pojawia się w:
    Polish Journal of Otolaryngology
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
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