- Tytuł:
- Thionylchloride catalyzed aldol condensation: Synthesis, spectral correlation and antibacterial activities of some 3,5-dichloro-2-hydroxyphenyl chalcones
- Autorzy:
-
Arulkumaran, R.
Vijayakumar, S.
Sundararajan, R.
Sakthinathan, S. P.
Kamalakkannan, D.
Suresh, R.
Ranganathan, K.
Vanangamudi, G.
Thirunarayanan, G. - Powiązania:
- https://bibliotekanauki.pl/articles/411825.pdf
- Data publikacji:
- 2012
- Wydawca:
- Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
- Tematy:
-
chlorek tionylu
widma IR i NMR
korelacja Hammeta
aktywność antybakteryjna
wpływ podstawników
styrylo 3,5-dichloro-2-hydroksy fenylo ketony
thionyl chloride
styryl 3,5-dichloro-2-hydroxyphenyl ketones
IR and NMR spectra
Hammett correlation
substituent effects
antimicrobial activities - Opis:
- A series of substituted styryl 3,5-dichloro-2-hydroxyphenyl ketones [1-(3, 5-dichloro-2-hydroxy)- 3-phenylprop-2-en-1-one] were synthesized using thionyl chloride assisted Crossed Aldol reaction. The yields of chalcones were more than 80%. The synthesized chalcones were characterized by analytical and spectroscopic data. From the spectroscopic data the group frequencies were correlated with Hammett substituent constants, F and R parameters. From the results of statistical analysis the effect of substituents were discussed. The antibacterial activities of these chalcones have been evaluated using Bauer-Kirby method.
- Źródło:
-
International Letters of Chemistry, Physics and Astronomy; 2012, 4; 17-38
2299-3843 - Pojawia się w:
- International Letters of Chemistry, Physics and Astronomy
- Dostawca treści:
- Biblioteka Nauki
Artykuł