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Wyszukujesz frazę "keratitis" wg kryterium: Temat


Tytuł:
A 3-year retrospective review of corneal ulcers in Hospital Universiti Sains Malaysia
Autorzy:
Yap, Jin Yi
Voon Tan, Kaai
Khairy-Shamel, Sonny-Teo
Powiązania:
https://bibliotekanauki.pl/articles/552069.pdf
Data publikacji:
2019
Wydawca:
Stowarzyszenie Przyjaciół Medycyny Rodzinnej i Lekarzy Rodzinnych
Tematy:
keratitis
cornea
Malaysia.
Opis:
Background. Microbial keratitis which is also known as corneal ulcer, is a common ocular infection that can result in debilitating monocular visual impairment. Identifying the prevalence and the latest trend of the causative agents will be useful in the management of corneal ulcer. Objectives. To evaluate the demographic and epidemiology factors of microbial keratitis at a tertiary hospital in a rural state of Malaysia. Material and methods. This is a retrospective review with a total recruit of 137 patients who were admitted to the Ophthalmology ward in Hospital Universiti Sains Malaysia. A retrospective review of the demographic data and results of corneal tissue sampling were documented. Results. Demographic data showed similarity to other studies where it affected most commonly in the productive age. It was also more commonly seen in male patients than in female. Bacterial keratitis (51.1%) was found to be more common than fungal keratitis (24.8%). In cases of bacterial keratitis, Pseudomonas spp. was the commonest causative agent, while in cases of fungal keratitis, Fusarium spp. was the commonest fungus microbial agent. Conclusions. With the knowledge of the demographical and epidemiological factors of microbial keratitis of a region, clinicians will be able to initiate prompt treatment at the early stages of the disease. Thus, less complications will arise from the disease and a better visual outcome provided.
Źródło:
Family Medicine & Primary Care Review; 2019, 1; 62-65
1734-3402
Pojawia się w:
Family Medicine & Primary Care Review
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Feline ocular toxoplasmosis: seroprevalence, diagnosis and treatment outcome of 60 clinical cases
Autorzy:
Ali, K.M.
Abu-Seida, A.M.
Abuowarda, M.
Powiązania:
https://bibliotekanauki.pl/articles/2087214.pdf
Data publikacji:
2021
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
cats
chorioretinitis
keratitis
seroprevalence
Toxoplasma gondii
uveitis
Źródło:
Polish Journal of Veterinary Sciences; 2021, 24, 1; 51-61
1505-1773
Pojawia się w:
Polish Journal of Veterinary Sciences
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Acanthamoeba in the Domestic Water Supply of Huntington, West Virginia, U.S.A.
Autorzy:
Trzyna, Wendy
Mbugua, Margaret W.
Rogerson, Andrew
Powiązania:
https://bibliotekanauki.pl/articles/763579.pdf
Data publikacji:
2010
Wydawca:
Uniwersytet Jagielloński. Wydawnictwo Uniwersytetu Jagiellońskiego
Tematy:
Amoebic Keratitis, amoebae, tap water, Acanthamoeba, chlorine tolerance
Opis:
The aim of this study was to determine the prevalence of Acanthamoeba in the domestic water supply in Huntington, West Virginia (U.S.A.) and the factors that may contribute to their presence or absence. One hundred sixty-two one liter tap water samples were collected over eight months. Amoebae in the samples (cysts or trophozoites) were harvested by passively filtering onto 5 μm pore size filters and enriching for amoebae on non-nutrient amoeba saline agar plates seeded with Escherichia coli for cultivation. Thirteen percent of all samples were positive for amoebae and 9.3% were positive for the amoeba of interest, Acanthamoeba. Chlorine levels were determined for samples at the time of collection, yielding a mean level of 1.56 mg l–1 chlorine in the distribution system ca. 8 kilometers from the water treatment plant. Cysts and trophozoites of Acanthamoeba clonal isolates were found to tolerate up to 50 mg l–1 and 4 mg l–1 chlorine respectively. This study showed that Acanthamoeba were present in the domestic water supply in Huntington, WV and although no attempt was made to count cells in liter samples, their frequency of occurrence (9.3%) and failure to be present in all replicates, suggests they were present at background levels of perhaps a few cells per five liters. This is only the second U.S. study to consider amoebae in tap water and is unique since the source water was river water. Acanthamoeba trophozoites and cysts were able to withstand levels of chlorine higher than those typically found in tap water suggesting they may be present in either form in the distribution system. Acanthamoeba are opportunistic pathogens capable of causing eye infections and their presence in tap water is a potential risk factor for susceptible individuals, particularly contact lens wearers who may use tap water to clean lenses and storage cases.
Źródło:
Acta Protozoologica; 2010, 49, 1
1689-0027
Pojawia się w:
Acta Protozoologica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Clinical study on the application of dexamethasone and cyclosporine/dimethyl sulfoxide combination eye drops in the initial therapy of chronic superficial keratitis in dogs
Autorzy:
Balicki, I.
Szadkowski, M.
Balicka, A.
Zwolska, J.
Powiązania:
https://bibliotekanauki.pl/articles/2087091.pdf
Data publikacji:
2021
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
chronic superficial keratitis
German Shepherd
cyclosporine
DMSO
Źródło:
Polish Journal of Veterinary Sciences; 2021, 24, 3; 415-423
1505-1773
Pojawia się w:
Polish Journal of Veterinary Sciences
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Tolerance of Naked Amoebae to Low Oxygen Levels with an Emphasis on the Genus Acanthamoeba
Autorzy:
Cometa, Ivan
Schatz, Scott
Trzyna, Wendy
Rogerson, Andrew
Powiązania:
https://bibliotekanauki.pl/articles/763676.pdf
Data publikacji:
2011
Wydawca:
Uniwersytet Jagielloński. Wydawnictwo Uniwersytetu Jagiellońskiego
Tematy:
Amoebic Keratitis, microaerophilic, naked amoebae, migration, biofilms
Opis:
Amoebae feed on attached bacteria within, and below, bacterial biofilms where they experience reduced oxygen levels. The implications of this were examined by comparing the migration (an index of growth) of thirteen strains of Acanthamoeba and five species of naked amoebae grown under microaerophilic and aerobic conditions. All amoebae replicated well under both conditions and twelve isolates migrated significantly faster under low oxygen. Only one isolate, Vannella sp., migrated further (presumably grew faster) under aerobic conditions. The data show most amoebae prefer low oxygen as befits the biofilm habitat. Interestingly, the eleven acanthamoeba strains that replicated faster under microaerophilic conditions were all T4 genotypes and included four strains isolated from patients with amoeba keratitis (AK) infections. This genotype is most frequently found in AK cases and it is suggested that strains of Acanthamoeba capable of rapid growth in a biofilm of a poorly cleansed contact lens may enable amoebae to multiply and provide an infective dos e when placed onthe cornea.
Źródło:
Acta Protozoologica; 2011, 50, 1
1689-0027
Pojawia się w:
Acta Protozoologica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
The most common eye disease in cat
Choroby oczu występujące często u kotów
Autorzy:
Trbolova, A.
Powiązania:
https://bibliotekanauki.pl/articles/9971.pdf
Data publikacji:
2011
Wydawca:
Okulistyka Weterynaryjna
Tematy:
cat
animal disease
eye disease
agenesia
ankyloblepharon
coloboma
neoplasia
cornea disease
herpetic keratitis
keratitis
sequestrum
uveitis
hypertension
taurine deficiency retinopathy
Opis:
Wiele chorób oczu kotów różni się od tych które spotykamy u inny gatunków zwierząt. Typowo kocim schorzeniem jest sequestrum czyli martwak rogówki. Ogólne objawy ze strony oczu kota są zwykle powiązane z istnieniem choroby systemowej, toczącej się w całym organizmie (choroby tła wirusowego, pasożytnicze, grzybice, nadciśnienie). Oczy kotów wrażliwe są na niedobory tauryny  czy też tiaminy, które to powodują zmiany chorobowe dna oka prowadzące do ślepoty. Bardzo często spotykamy u kotów nowotwory, które są zwykle bardziej agresywne niż u innych gatunków zwierząt. Ponadto występują też schorzenia o podłożu genetycznym i wady rozwojowe.
Źródło:
Okulistyka Weterynaryjna. e-kwartalnik dla lekarzy i studentów weterynarii; 2011, 2
2082-9256
Pojawia się w:
Okulistyka Weterynaryjna. e-kwartalnik dla lekarzy i studentów weterynarii
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
In vivo confocal microscopy and in vitro culture techniques as tools for evaluation of severe Acanthamoeba keratitis incidents
Autorzy:
Padzik, Monika
Szaflik, Jacek P.
Baltaza, Wanda
Perkowski, Konrad
Dybycz, Monika
Chomicz, Lidia
Powiązania:
https://bibliotekanauki.pl/articles/972158.pdf
Data publikacji:
2017
Wydawca:
Polskie Towarzystwo Parazytologiczne
Tematy:
Acanthamoeba keratitis
in vitro cultivation
in vivo confocal microscopy
Opis:
Amphizoic amoebae belonging to the genus Acanthamoeba are known as etiological agents of sightthreatening Acanthamoeba keratitis. The leading risk factor for the development of this serious human disease is contact lens wearing which popularity increases worldwide, also in Poland. The disease with active epithelial inflammations, corneal ulcers, including loss of the visual acuity is a serious medical problem as an emerging threat for the public health related to improper contact lens hygiene. The treatment of the amoebic keratitis is difficult, often unsuccessful due to delayed proper diagnosis. The clinical picture of the disease, often with severe course is nonspecific, similar to that occurring in viral, fungal or bacterial keratitis, thus clinical symptoms alone are not sufficient to identify the causative agent of the amoebic infection. Early diagnosis is decisive for the suitable therapeutic management and the treatment efficacy. In our studies, several complicated, difficult to treat Acanthamoeba keratitis incidences pertaining Polish patients using contact lenses have been retrospectively analyzed in terms of the usefulness of non-invasive methods of in vivo confocal microscopy and in vitro culture techniques applied for diagnosis. Hyper-reflective double-walled spherical Acanthamoeba cysts, with a more reflective outer wall were detected in the epithelium and anterior layers of the corneal stroma. In vivo confocal microscopy, if available, may be a valuable, sensitive tool for diagnosis in late identified severe infections mainly with strong viability strains, however confoscan may offer limited value at lowintensity amoebic infections. The microscopic visualization of amoebae in slides prepared directly from corneal scraping and laboratory examinations of specimens from in vitro cultivated corneal isolates allow to confirm or verify results of in vivo examinations, furthermore to identify directly the pathogens and to clarify previous misdiagnoses.
Źródło:
Annals of Parasitology; 2017, 63, 4; 341-346
0043-5163
Pojawia się w:
Annals of Parasitology
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
A single-centre retrospective observational study of fungal keratitis in Poland with a review of findings in Europe
Autorzy:
Nowik, K.E.
Wylęgała, A.
Nowik, K.
Wylęgała, E.
Powiązania:
https://bibliotekanauki.pl/articles/2085863.pdf
Data publikacji:
2020
Wydawca:
Instytut Medycyny Wsi
Tematy:
fungal keratitis
keratomycosis
confocal microscopy
keratoplasty
yeast
filamentous
Opis:
Introduction. Fungal keratitis is a severe condition which may lead to blindness. Fungal keratitis, also known mycotic keratitis or keratomycosis, has worldwide distribution, but is more common in tropical climates compared to moderate zones. In recent years, there have been several studies suggesting an increase in the number of mycotic keratitis cases in countries with a moderate climate. There is little data available with no literature review concerning fungal keratitis in European countries. Objective. To analyse the causes, presentation, and clinico-pathological associations of fungal keratitis in a retrospective series of patients referred to the Department of Ophthalmology of the Railway Hospital in Katowice, south-west Poland, and comparing the findings to previously published studies in peer reviewed articles from other European countries published between 2000–2019. Materials and method. Data were collected using the medical records of patients with fungal keratitis. Risk factors, clinical manifestation and treatment results were analysed from 45 patients (45 eyes) with fungal keratitis treated in the Department of Ophthalmology of Railway Hospital in Katowice between January 2013 – December 2017. The factors affecting the development of infection, visual acuity at baseline and at the end of treatment, as well as treatment method selection, were analysed. Literature review was performed using the Medline, Pubmed, Embase databases and Google scholar. The inclusion criteria were peer reviewed papers published between 2000–2019 which reported data from patients with fungal keratitis in at least one European country. 11 peer reviewed articles which matched the inclusion criteria were analysed. Results. The mean BCVA of patients treated in the Department of Ophthalmology of the Railway Hospital in Katowice upon diagnosis was 2.3 (logMAR), compared to 1.95 (logMAR) at the end of treatment. Pearson’s chi-squared test was used to establish the final mean BCVA in eyes with keratitis caused by Candida spp. compared with keratitis caused by Filamentous spp. The reviewed articles showed poor results of treatment and diagnostic difficulties in fungal keratitis. Conclusions. Fungal keratitis is a significant diagnostic and therapeutic challenge and may occur in rural and urban areas. Early and accurate diagnosis followed by proper antifungal treatment can prevent blindness and improve BCVA results.
Źródło:
Annals of Agricultural and Environmental Medicine; 2020, 27, 3; 343-347
1232-1966
Pojawia się w:
Annals of Agricultural and Environmental Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Contact lens-related combined Pseudomonas aeruginosa, Acanthamoeba and Candida keratitis among adolescents girls
Autorzy:
Świerczyńska, Marta
Tronina, Agnieszka
Bogocz, Michał
Mrukwa-Kominek, Ewa
Filipek, Erita
Powiązania:
https://bibliotekanauki.pl/articles/2046699.pdf
Data publikacji:
2022-03-31
Wydawca:
Medical Education
Tematy:
infectious keratitis
contact lenses
Candida
Acanthamoeba
Pseudomonas aeruginosa
Opis:
Background: We present a case of combined Pseudomonas aeruginosa, Acanthamoeba and Candida keratitis and clinical course of treatment in two adolescents girls who did not follow the rules of proper use of soft contact lenses. Case reports: Two teenage contact lens users sought medical attention, reporting visual impairment, redness and pain of the eye. Slit lamp examination showed unilateral corneal ulcer. Confocal microscopy revealed images compatible with amoebic cysts and yeasts cells, whereas the results of conjunctival swabs confirmed the presence of Pseudomonas aeruginosa. After topical and general treatment in the first patient, the corneal defect was healed, and visual acuity improved. The girl remains under the constant supervision of an ophthalmological clinic. The medications were gradually reduced, but with time she developed crystalline keratopathy. Regrettably, the second patient, despite the applied treatment had recurrent inflammation and progressive corneal thinning, which required amniotic membrane transplantation to prevent perforation. Conclusion: The early identification of the pathogen as well as adequate treatment is crucial, as contact lens-associated keratitis are potentially sight threatening. Patient and caregiver education, adequate contact lens hygiene and consistent follow-up are important to prevent serious complications.
Źródło:
OphthaTherapy; 2022, 9, 1; 36-44
2353-7175
2543-9987
Pojawia się w:
OphthaTherapy
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Conjunctival herpetic ulcer in an immunosuppressed patient with birdshot chorioretinopathy
Autorzy:
Fernández-Hortelano, Ana
Guzmán-Almagro, Elena
Rebollo, María Castro
Rodríquez, Carlos Izquierdo
Martín-Moro, Julio González
Powiązania:
https://bibliotekanauki.pl/articles/2042908.pdf
Data publikacji:
2021-08-27
Wydawca:
Medical Education
Tematy:
conjunctival ulcers
herpetic keratitis
Herpes simplex virus
birdshot chorioretinopathy
immunosuppression
topical steroids
Opis:
Introduction: Herpes Simplex Virus (HSV) is a human herpesvirus responsible for systemic infections. Ocular involvement spans all ocular tissues. Corneal lesions, such as dendritic or geographic ulcers, are frequently found in HSV keratitis while conjunctival lesions have been described as infrequent. Clinical case: A 62-year-old man diagnosed with Birdshot chorioretinopathy presented a stye in his eyelid that was treated with oxytetracycline-hydrocortisone ointment. One week later he returned presenting several small dendritic corneal ulcers in both eyes and a conjunctival ulcer in one of them. All lesions healed completely after treatment with topical acyclovir ophthalmic ointment at 3%. Conclusions: We should pay attention to the conjunctiva and not merely focus on the cornea when examining patients with herpetic eye disease, especially if being treated with inmunosupressors.
Źródło:
OphthaTherapy; 2021, 8, 3; 175-178
2353-7175
2543-9987
Pojawia się w:
OphthaTherapy
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
The confocal microscopy, the tool for rapid in vivo diagnosis of Acanthamoeba keratitis - usefulness and limitations
Autorzy:
Chomicz, L.
Izdebska, J.
Padzik, M.
Baltaza, W.
Pionkowski, K.
Jasniewska, E.
Dybicz, M.
Powiązania:
https://bibliotekanauki.pl/articles/5676.pdf
Data publikacji:
2016
Wydawca:
Polskie Towarzystwo Parazytologiczne
Tematy:
confocal microscopy
rapid diagnosis
in vivo diagnosis
Acanthamoeba keratitis
amoeba
parasite
usefulness
limitation
Źródło:
Annals of Parasitology; 2016, 62, Suppl.
0043-5163
Pojawia się w:
Annals of Parasitology
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Feline herpesvirus-1: Ocular manifestations, diagnosis and treatment options
Choroby oczu kotów wywołane zakażeniami herpesvirusem-1: Objawy kliniczne, diagnostyka i sposoby leczenia
Autorzy:
Gould, D.
Powiązania:
https://bibliotekanauki.pl/articles/9976.pdf
Data publikacji:
2012
Wydawca:
Okulistyka Weterynaryjna
Tematy:
cat
animal disease
feline herpesvirus 1
diagnosis
treatment
ocular manifestation
keratitis
conjunctivitis
animal exposure
ocular disease
Opis:
W swojej pracy autor przedstawia kluczowe aspekty związane z chorobami oczu występującymi u kotów, które  powoduje  herpesvirus  koci typu 1. Praca  w obszerny sposób omawia wiele chorób implikowanych tym typem wirusa. szczegółowo opisuje objawy kliniczne poszczególnych schorzeń, diagnostykę oraz doradza w sposób praktyczny dobieranie odpowiedniego leczenia. Mamy podany szereg leków wraz z dawkami i sposobami ich podania dla poszczególnych schematów leczenia. Praca jest bogato ilustrowana fotografiami obrazującymi konkretne przypadki kliniczne. Autor włożył wiele wysiłku, dzięki czemu powstała naprawdę wspaniała praca naukowa, która praktykom daje gotowy schemat rozpoznawania i leczenia tych trudnych z punktu klinicznego chorób.
Practical relevance Feline herpesvirus-1 (FHV-1) is a major cause of feline morbidity. Following exposure to the virus, virtually all cats become persistently infected and many of these will develop recrudescent disease on one or more occasions during their life. Ocular manifestations include conjunctivitis, corneal ulceration and keratitis. In severe cases the condition can be blinding. Global importance FHV-1 has a worldwide distribution, with reported exposure rates in some cat populations of up to 97%. As such it is a significant cause of clinical disease in the global cat population. Patient Group Young and adolescent cats are most at risk of acute primary disease, and the vast majority of these will then become persistently infected. Around half of all persistently infected cats will shed virus at some stage in their life and these may develop recrudescent ocular disease. Clinical challenges Acute ocular herpetic disease can be severe and painful. Repeated bouts of recrudescent ocular disease can lead to progressive corneal pathology that can be ultimately blinding in affected cats. Treatment of FHV-1 ocular disease is challenging. Antiviral medications may be expensive and require good owner and patient compliance. Clinical responses in patients can be variable. Selecting the appropriate therapeutic approach requires good clinical judgement and depends on a number of factors such as severity and stage of clinical disease, patient and owner compliance and financial considerations. Evidence base Although a wide range of antiviral treatments are available, very few of these have been tested in controlled clinical trials. Instead, therapeutic decisions are often made based on results of in vitro studies, case-based reports and anecdote. Large, masked, controlled clinical trials are required in order to determine the efficacy of the antiviral drugs currently available to treat FHV-1.
Źródło:
Okulistyka Weterynaryjna. e-kwartalnik dla lekarzy i studentów weterynarii; 2012, 2
2082-9256
Pojawia się w:
Okulistyka Weterynaryjna. e-kwartalnik dla lekarzy i studentów weterynarii
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Rational therapy of ocular surface bacterial infections with fluoroquinolones
Racjonalna terapia bakteryjnych zakażeń powierzchni oka z zastosowaniem fluorochinolonów
Autorzy:
Trojacka, Ewelina
Izdebska, Justyna
Powiązania:
https://bibliotekanauki.pl/articles/2159022.pdf
Data publikacji:
2022-06-30
Wydawca:
Medical Education
Tematy:
bacterial conjunctivitis
bacterial keratitis
ophthalmic fluoroquinolones
moxifloxacin
bakteryjne zapalenie spojówek
bakteryjne zapalenie rogówki
oczne fluorochinolony
moksyfloksacyna
Opis:
There are many mechanisms, that protect healthy ocular surface from invasion of pathogenic bacteria. Infection and inflammation develop on the ocular surface in case of damaging natural defensive barrier. One of the most common ocular surface infections are bacterial conjunctivitis and keratitis. Rational therapy of these diseases should be based on antibiotics that have broad antimicrobial spectrum, good efficacy and safety. All these qualities have fluoroquinolones: ofloxacin, levofloxacin and moxifloxacin.
Prawidłowa powierzchnia oka ma szereg mechanizmów chroniących ją przed inwazją bakterii chorobotwórczych. W przypadku przełamania fizjologicznej bariery dochodzi do rozwoju zakażenia i stanu zapalnego. Jednymi z częstszych chorób zakaźnych powierzchni oka są bakteryjne zapalenia spojówek i rogówki. Terapia tych schorzeń powinna bazować na racjonalnym stosowaniu antybiotyków o szerokim spektrum działania przeciwbakteryjnego, wysoce skutecznych i bezpiecznych. Wszystkie powyższe cechy maja fluorochinolony: ofloksacyna, lewofloksacyna i moksyfloksacyna.
Źródło:
OphthaTherapy; 2022, 9, 2; 119-123
2353-7175
2543-9987
Pojawia się w:
OphthaTherapy
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Evaluation of in vitro effect of selected contact lens solutions conjugated with nanoparticles in terms of preventive approach to public health risk generated by Acanthamoeba strains
Autorzy:
Padzik, M.
Hendiger, E.B.
Żochowska, A.
Szczepaniak, J.
Baltaza, W.
Pietruczuk-Padzik, A.
Olędzka, G.
Chomicz, L.
Powiązania:
https://bibliotekanauki.pl/articles/2082951.pdf
Data publikacji:
2019
Wydawca:
Instytut Medycyny Wsi
Tematy:
Acanthamoeba keratitis
contact lens solutions
silver/gold nanoparticles
Acanthamoeba trophozoites
anti-amoebic in
vitro effect
Opis:
Introduction. Various Acanthamoeba species are free-living organisms widely distributed in the human environment. Amphizoic amoebae as facultative parasites may cause vision-threatening eye disease – Acanthamoeba keratitis, mostly among contact lens wearers. As the number of cases is increasing, and applied therapy often unsuccessful, proper hygienic measures and effective contact lenses disinfection are crucial for the prevention of this disease. Available contact lens solutions are not fully effective against amphizoic amoebae; there is a need to enhance their disinfecting activity to prevent amoebic infections. The use of developing nanotechnology methods already applied with success in the prevention, diagnostic and therapy of other infectious diseases might be helpful regarding amoebic keratitis. This study assesses the in vitro effect of selected contact lens solutions conjugated with nanoparticles against Acanthamoeba trophozoites. Materials and method. Three selected contact lens solutions conjugated with silver and gold nanoparticles in concentration of 0.25–2.5 ppm were used in vitro against the axenically cultured ATCC 30010 type Acanthamoeba castellanii strain. The anti-amoebic efficacy was examined based on the oxido-reduction of AlamarBlue. The cytotoxicity tests based on the measurement of lactate dehydrogenase (LDH) activity were performed using a fibroblast HS-5 cell line. Results. Enhancement of the anti-amoebic activity of contact lens solutions conjugated with selected nanoparticles expressed in the dose dependent amoebic growth inhibition with a low cytotoxicity profile was observed. Conclusions. Results of the study showed that conjugation of selected contact lens solutions with silver nanoparticles might be a promising approach to prevent Acanthamoeba keratitis among contact lens users.
Źródło:
Annals of Agricultural and Environmental Medicine; 2019, 26, 1; 198-202
1232-1966
Pojawia się w:
Annals of Agricultural and Environmental Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Secondary amoebic eye infections in mice due to Acanthamoeba sp.
Autorzy:
Mazur, T.
Hadas, E.
Gustowska, L.
Winiecka-Krusnell, J.
Linder, E.
Powiązania:
https://bibliotekanauki.pl/articles/838373.pdf
Data publikacji:
1998
Wydawca:
Polskie Towarzystwo Parazytologiczne
Tematy:
Acanthamoeba
Acanthamoeba keratitis
mouse
infection
mice
eye
amoeba
Acanthamoeba castellanii
Acanthamoeba polyphaga
central nervous system
Źródło:
Annals of Parasitology; 1998, 44, 3
0043-5163
Pojawia się w:
Annals of Parasitology
Dostawca treści:
Biblioteka Nauki
Artykuł

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