Temat: interleukin 10 - Katalog OPAC zbiorów

Skocz do pozycji: 1.

Tytuł:: Inhibition of tumor growth by interleukin 10 gene transfer in B16(F10) melanoma cells
Autorzy:: Walos, Sylwia
Szary, Jarosław
Szala, Stanisław
Powiązania:: https://bibliotekanauki.pl/articles/1044456.pdf
Data publikacji:: 1999
Wydawca:: Polskie Towarzystwo Biochemiczne
Tematy:: B16(F10) murine melanoma
antiangiogenic effect
interleukin 10
Opis:: Interleukin 10 (IL-10) is a potent immunosuppressive cytokine with an antitumor activity. The effect of IL-10 on tumor growth was tested in murine melanoma cells manipulated by gene transfer to secrete IL-10. In mice bearing B16(F10) tumors expressing IL-10 tumor growth was decreased depending on the amount of secreted IL-10.
Źródło:: Acta Biochimica Polonica; 1999, 46, 4; 967-970
0001-527X
Pojawia się w:: Acta Biochimica Polonica
Dostawca treści:: Biblioteka Nauki

Artykuł

Zmień widok

na półce

Skocz do pozycji: 2.

Tytuł:: Pancreatic damage and regeneration in the course of ischemia-reperfusion induced pancreatitis in rats
Autorzy:: Dembinski, A.
Warzecha, Z.
Ceranowicz, P.
Stachura, J.
Tomaszewska, R.
Konturek, S.J.
Sendur, R.
Dembinski, M.
Pawlik, W.W.
Powiązania:: https://bibliotekanauki.pl/articles/71095.pdf
Data publikacji:: 2001
Wydawca:: Polskie Towarzystwo Fizjologiczne
Tematy:: acute pancreatitis
pancreatic damage
pancreatic blood flow
interleukin 1beta
DNA synthesis
pancreatitis
interleukin 10
ischaemia
regeneration
rat
Źródło:: Journal of Physiology and Pharmacology; 2001, 52, 2
0867-5910
Pojawia się w:: Journal of Physiology and Pharmacology
Dostawca treści:: Biblioteka Nauki

Artykuł

Zmień widok

na półce

Skocz do pozycji: 3.

Tytuł:: Differential responses of hematopoietic and non-hematopoietic cells to anti-inflammatory cytokines: IL-4, IL-13 and IL-10
Autorzy:: Guzdek, A.
Stalinska, K.
Guzik, K.
Koj, A.
Powiązania:: https://bibliotekanauki.pl/articles/69534.pdf
Data publikacji:: 2000
Wydawca:: Polskie Towarzystwo Fizjologiczne
Tematy:: non-hematopoietic cell
macrophage
interleukin 10
blood
hepatoma
antiinflammatory cytokine
in vitro
hematopoietic cell
interleukin 4
man
tumour necrosis factor-alpha
cytokine
interleukin 13
monocyte
Źródło:: Journal of Physiology and Pharmacology; 2000, 51, 3
0867-5910
Pojawia się w:: Journal of Physiology and Pharmacology
Dostawca treści:: Biblioteka Nauki

Artykuł

Zmień widok

na półce

Skocz do pozycji: 4.

Tytuł:: The presence of CD25 on bovine WC1 plus gamma delta T cells is positively correlated with their production of IL-10 and TGF-beta, but not IFN-gamma
Autorzy:: Maslanka, T.
Jaroszewski, J.J.
Markiewicz, W.
Ziolkowski, H.
Barski, D.
Powiązania:: https://bibliotekanauki.pl/articles/32183.pdf
Data publikacji:: 2012
Wydawca:: Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:: cattle
WC1 cell
T cell
T lymphocyte
transforming growth factor-beta
interleukin 10
interferon-gamma
CD25 antigen
CD25 molecule
Opis:: WC1+ cells in cattle exhibit both regulatory and effector activities. However, it has not been elucidated whether they are so plastic that both activities co-exist in one cell or there are separate subpopulations of effector and regulatory cells. Since the production of IFN-γ and IL-10 seems to be related to WC1+ cells’ effector and regulatory function, respectively, the main aim of this study was to determine whether those cytokines are produced by separate subpopulations of WC1+, or are co-produced by the same cells. Due to increasingly frequent emphasised role of consumption of IL-2 in the mechanism of suppressor action of mouse CD25+CD4+ T regulatory cells, expression of the receptor’s α chain for interleukin 2 (CD25) on WC1+ lymphocytes has been evaluated. An average of 5.21% of WC1+ cells obtained from PBMCs of 12-month-old heifers show constitutive expression of the CD25 molecule, with CD25highWC1+ and CD25lowWC1+ cells accounting for 1.05% and 4.10% of WC1+ lymphocytes, respectively. For detection of intracellular cytokine production, PBMCs were stimulated with concanavalin A. Both IFN-γ- and IL-10-producing cells within the CD25-WC1+ and CD25+WC1+ subpopulations were mainly separate subpopulations. The average percentage of IFN-γ+IL-10-, IFN-γ-IL-10+ and IFN-γ+IL-10+ cells among CD25-WC1+ lymphocytes was 4.03%, 2.67% and 0.51%, respectively. A positive correlation was observed between the presence of the CD25 molecule on WC1+ lymphocytes and production of IL-10 and TGF-β, because the average percentage of IFN-γ-IL-10+ and IFN-γ+IL-10+ among CD25+WC1+ lymphocytes was 3 and 4.5 times higher as compared to the corresponding cells in the CD25-WC1+ subpopulation, whereas the percentage of IFN-γ+IL-10- cells in both the subpopulations was not significantly different. The percentage of TGF-β+ cells within the CD25+WC1+ subpopulation was 2.72 times as high as that of CD25-WC1+ lymphocytes. Therefore, with respect to the production of IFN-γ, IL-10 and TGF-β, CD25+WC1+ lymphocytes turn out to have a more suppressor profile than CD25-WC1+.
Źródło:: Polish Journal of Veterinary Sciences; 2012, 15, 1
1505-1773
Pojawia się w:: Polish Journal of Veterinary Sciences
Dostawca treści:: Biblioteka Nauki

Artykuł

Zmień widok

na półce

Skocz do pozycji: 5.

Tytuł:: On the peptide-antipeptide interactions in interleukin-1 receptor system.
Autorzy:: Kluczyk, Alicja
Cebrat, Marek
Zbozień-Pacamaj, Renata
Lisowski, Marek
Stefanowicz, Piotr
Wieczorek, Zbigniew
Siemion, Ignacy
Powiązania:: https://bibliotekanauki.pl/articles/1043318.pdf
Data publikacji:: 2004
Wydawca:: Polskie Towarzystwo Biochemiczne
Tematy:: vaccinia virus C10L protein
immunomodulation
interleukin-1 receptor antagonist
complementary peptides
interleukin-1
Opis:: Interleukin-1 receptor antagonist (IL-1Ra) and vaccinia virus protein C10L share a VTXFYF motif, with X being Lys or Arg residue, respectively. Peptides of such sequence compete successfully with IL-1 for the cellular receptor. A pair of complementary peptides, based on the Siemion's hypothesis on the periodicity of the genetic code (QWLNIN and QWANIN), and another pair, in which, following the Root- Bernstein theory, Lys was used as complementary amino acid to Phe (QWLKIK and QWAKIK), were investigated for the peptide-antipeptide interactions using mass spectrometry (ESI-MS) and circular dichroism (CD) methods. The CD measurements indicated some conformational changes, more pronounced in the Siemion's pairs, however, no heterodimer formation was found by MS. In the region of IL-1 receptor situated close to the position of IL-1Ra in the IL-1Ra-receptor complex, a KQKL motif is present, suggesting a possibility of complementary recognition of the Root-Bernstein type in the IL-1 receptor. The biological activity of the complementary peptides is similar to that of the original ones. They efficiently compete with IL-1 and show moderate immunosuppressory activity in humoral and cellular immune response. The inhibition of the IL-1-IL-1 receptor interaction may result from the complementary peptides acting as mini-receptors with affinity for IL-1.
Źródło:: Acta Biochimica Polonica; 2004, 51, 1; 57-66
0001-527X
Pojawia się w:: Acta Biochimica Polonica
Dostawca treści:: Biblioteka Nauki

Artykuł

Zmień widok

na półce

Informacja

Wyszukujesz frazę "interleukin 10" wg kryterium: Temat

Źródło danych

Dostawca treści

Kolekcja

Rok wydania

Wydawca

Temat

Autor

Typ dokumentu

Język