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Tytuł:
К вопросу экологии природноочаговых болезней (концептуально-аналитические исследования)
To the issue of the ecology of environmental focal diseases (conceptual-analytical study)
Autorzy:
Golubyatnikov, M.
Sidenko, V.
Powiązania:
https://bibliotekanauki.pl/articles/1032516.pdf
Data publikacji:
2014
Wydawca:
Uniwersytet Kazimierza Wielkiego w Bydgoszczy
Tematy:
природноочаговые болезни
вирус гриппа
эпидемический процесс
environmental focal diseases
influenza virus
epidemic processes.
Opis:
К вопросу экологии природноочаговых болезней (концептуально-аналитические исследования) Проведены научно-аналитические исследования по проблеме экологии природноочаговых болезней. Основываясь на современных данных молекулярной биологии, вирусологии, иммунологии и эпидемиологии, авторы полагают, что происхождение биогенетических межвидовых экологических связей основывается на сапронозной природе, в частности, вирусов гриппа. На предадаптивной стадии миграционного процесса может стимулироваться возникновение некоторых вариантов, к которым восприимчивы околоводные птицы, а также отдельные млекопитающие, в том числе и человек. Разработка мер, препятствующих реассортации ныне является основой профилактики этой вирусной инфекции в будущем.
To the issue of the ecology of environmental focal diseases (conceptual-analytical study) There was conducted the scientific-analytical study on the problem of the ecology of environmental focal diseases. Substantiated on the modern data of molecular biology, virology, immunology and epidemiology, the authors suggests that the origin of biogenetic interspecies associations are based on the sapronotic nature of influenza virus, particularly. On the preadaptive stage of migration process there are stimulated the occurrence of the variants whereas the water birds and mammalians, including humans, are susceptible. The development of the measures preventing reassociation is a base of the prevention of this viral infection in the future.
Źródło:
Journal of Health Sciences; 2014, 4, 1; 41-50
1429-9623
Pojawia się w:
Journal of Health Sciences
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Zakażenia wirusowe układu oddechowego w środowisku pracy służby zdrowia
Virus infections of the respiratory system in the occupational environment of health care employees
Autorzy:
Roży, A.
Jaguś, P.
Chorostowska-Wynimko, J.
Powiązania:
https://bibliotekanauki.pl/articles/179611.pdf
Data publikacji:
2014
Wydawca:
Centralny Instytut Ochrony Pracy
Tematy:
zakażenia wirusowe
wirusy oddechowe
wirus grypy
personel medyczny
viral infections
respiratory viruses
influenza virus
health care workers
Opis:
Infekcje wirusowe dróg oddechowych stanowią poważny problem zdrowotny i ekonomiczny na całym Świecie wysoka zakaźność tej grupy wirusów bezpośrednio wynika z łatwości transmisji, szczególnie w większych skupiskach ludzkich, takich jak placówki medyczne i oświatowe, duże zakłady pracy czy środki transportu. Ryzyko zakażenia dla tych grup zawodowych, a zwłaszcza pracowników ochrony zdrowia fest więc znacząco wyższe. Konieczne jest świadome stosowanie zasad profilaktyki czynnej (szczepienia ochronne), a w okresie wzrostu zapadalności również profilaktyki biernej (izolacja zakażonych, higiena). Niski poziom wyszczepialności przeciw grypie w populacji polskiej, w tym również wśród pracowników opieki zdrowotnej stanowi istotny problem, niosący znaczące ryzyko dla zdrowotności społeczeństwa i gospodarki kraju.
Respiratory viral infections pose a significant health and economic burden all over the world. Due to their easy transmission. respiratory viruses are highly infective, particularly in the larger human groupings, such as medical and educational facilities, larger industrial units and public transportation. Therefore, respective professional groups are regarded as the high risk population In those groups, in particular in medical staff, the premeditated proactive flu prophylaxis by means of regular immunization is strongly advised. A secondary prophylaxis, the strict isolation of infected patients must be introduced in health care facilities during flu season or epidemic. The unexceptionally low flu vaccination rate in Poland, both in general population and medical staff is of particular concern as a potential serious treat for society's state of health but also country economy.
Źródło:
Bezpieczeństwo Pracy : nauka i praktyka; 2014, 4; 27-29
0137-7043
Pojawia się w:
Bezpieczeństwo Pracy : nauka i praktyka
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Testing of human specimens for the presence of highly pathogenic zoonotic avian influenza virus A [H5N1] in Poland in 2006-2008 - justified or unnecessary steps?
Autorzy:
Romanowska, M
Nowak, I.
Brydak, L.B.
Wojtyla, A.
Powiązania:
https://bibliotekanauki.pl/articles/50626.pdf
Data publikacji:
2009
Wydawca:
Instytut Medycyny Wsi
Tematy:
avian influenza virus type A
zoonosis
influenza
H5N1 subtype
avian influenza
disease outbreak
diagnostic test
Polska
Źródło:
Annals of Agricultural and Environmental Medicine; 2009, 16, 2; 239-247
1232-1966
Pojawia się w:
Annals of Agricultural and Environmental Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Structural biology of the influenza virus fusion peptide
Autorzy:
Worch, Remigiusz
Powiązania:
https://bibliotekanauki.pl/articles/1039239.pdf
Data publikacji:
2014
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
influenza virus
viral entry
membrane fusion
fusion peptide
peptide-lipid interactions
Opis:
The release of influenza RNA inside the host cell occurs through the fusion of two membranes, the viral envelope and that of the cellular endosome. The fusion is mediated by the influenza hemagglutinin protein (HA), in particular by the fusion peptide (HAfp) located in the N-terminal fragment of HA2 subunit. This protein fragment anchors in the internal endosomal membrane, whereas the C-terminal HA2 part comprises a transmembrane domain (TMD) embedded in the viral envelope. A drop of pH in the endosome acts as the main trigger for HA2 large conformational change that leads to anchoring of the fusion peptide, close contact of the membranes and the subsequent fusion. Throughout the years the major research effort was focused on a 20-aminoacid fragment (HAfp1-20), shown by NMR to adopt a 'boomerang'-like structure. However, recent studies showed that extending HAfp1-20 by three highly conserved residues W21-Y22-G23 leads to formation of a unique, tight helical hairpin structure. This review summarizes recently discovered structural aspects of influenza fusion peptides and their relations with the membrane fusion mechanism.
Źródło:
Acta Biochimica Polonica; 2014, 61, 3; 421-426
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Serological surveillance of avian influenza virus and canine distemper virus in captive Siberian Tigers in Northeastern China
Autorzy:
Wang, K.
Wang, H.
Feng, N.
Zhao, Y.
Gao, Y.
Hu, G.
Xia, X.
Powiązania:
https://bibliotekanauki.pl/articles/2087698.pdf
Data publikacji:
2018
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
influenza A virus
canine distemper virus
serological
Siberian Tiger
Źródło:
Polish Journal of Veterinary Sciences; 2018, 21, 3; 491-495
1505-1773
Pojawia się w:
Polish Journal of Veterinary Sciences
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Role of the host genetic variability in the influenza A virus susceptibility
Autorzy:
Arcanjo, Ana
Mazzocco, Giovanni
de Oliveira, Silviene
Plewczynski, Dariusz
Radomski, Jan
Powiązania:
https://bibliotekanauki.pl/articles/1039238.pdf
Data publikacji:
2014
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
Influenza A virus
host-pathogen interactions
Opis:
The aftermath of influenza infection is determined by a complex set of host-pathogen interactions, where genomic variability on both viral and host sides influences the final outcome. Although there exists large body of literature describing influenza virus variability, only a very small fraction covers the issue of host variance. The goal of this review is to explore the variability of host genes responsible for host-pathogen interactions, paying particular attention to genes responsible for the presence of sialylated glycans in the host endothelial membrane, mucus, genes used by viral immune escape mechanisms, and genes particularly expressed after vaccination, since they are more likely to have a direct influence on the infection outcome.
Źródło:
Acta Biochimica Polonica; 2014, 61, 3; 403-419
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Possible computational filter to detect proteins associated to influenza A subtype H1N1
Autorzy:
Polanco, Carlos
Buhse, Thomas
Castañón-González, Jorge
Samaniego, José
Powiązania:
https://bibliotekanauki.pl/articles/1039197.pdf
Data publikacji:
2014
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
Polarity Index Method
influenza A virus subtype H1N1
drug design
QSAR method
Opis:
The design of drugs with bioinformatics methods to identify proteins and peptides with a specific toxic action is increasingly recurrent. Here, we identify toxic proteins towards the influenza A virus subtype H1N1 located at the UniProt database. Our quantitative structure-activity relationship (QSAR) approach is based on the analysis of the linear peptide sequence with the so-called Polarity Index Method that shows an efficiency of 90% for proteins from the Uniprot Database. This method was exhaustively verified with the APD2, CPPsite, Uniprot, and AmyPDB databases as well as with the set of antibacterial peptides studied by del Rio et al. and Oldfield et al.
Źródło:
Acta Biochimica Polonica; 2014, 61, 4; 693-698
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Phylogenetic analysis of swine influenza viruses isolated in Poland
Autorzy:
Kowalczyk, A
Markowska-Daniel, I.
Powiązania:
https://bibliotekanauki.pl/articles/30634.pdf
Data publikacji:
2010
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
pig
animal population
European population
swine influenza virus
H1N1 subtype
H3N3 subtype
phylogenetic analysis
isolation
Polska
Opis:
Swine influenza virus (SIV) of H1N1 and H3N2 subtypes are dominated in European pigs population. "Classical swine" H1N1 subtype was replaced by "avian-like" H1N1 subtype. It co-cir- culates with H3N2 reassortant possessing "avian" genes. In the present study, 41 SIV strains isolated from pigs with pneumonia, raised in 20 Polish farms, were identified and characterised. Since it was evidenced that isolates from the same geographic district and the same year of isolation are in 100% similar, 15 strains representing different district and different year of isolation were chosen to construct phylogenetic trees. Two genes, conservative matrix 1 (Ml) and the most variable, haemagglutynin (HA), were sequenced and subjected into phylogenetic analysis. The results of the analysis confirmed that "avian-like" swine H1N1 strains evolved faster than classical SIV strains. HA gene of these isolates have been derived from contemporary strains of "avian-like" SIV. In contrast, the Ml gene segment may have originated from avian influenza viruses. H3N2 strain is located in swine cluster, in the main prevalent European group of H3N2 isolates called A/Port Chalmers/l/73-like Eurasian swine H3N2 lineage, which has evolved separately from the human H3N2 virus lineage around 1973.
Źródło:
Polish Journal of Veterinary Sciences; 2010, 13, 1; 37-44
1505-1773
Pojawia się w:
Polish Journal of Veterinary Sciences
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Mapping of the influenza A hemagglutinin serotypes evolution by the ISSCOR method
Autorzy:
Radomski, Jan
Słonimski, Piotr
Zagórski-Ostoja, Włodzimierz
Borowicz, Piotr
Powiązania:
https://bibliotekanauki.pl/articles/1039244.pdf
Data publikacji:
2014
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
ISSCOR descriptors
phylogenetic analysis
influenza virus
hemagglutinin
phylogenetic maps
Opis:
Analyses and visualizations by the ISSCOR method of influenza virus hemagglutinin genes of different A-subtypes revealed some rather striking temporal relationships between groups of individual gene subsets. Based on these findings we consider application of the ISSCOR-PCA method for analyses of large sets of homologous genes to be a worthwhile addition to a toolbox of genomics - allowing for a rapid diagnostics of trends, and ultimately even aiding an early warning of newly emerging epidemiological threats.
Źródło:
Acta Biochimica Polonica; 2014, 61, 3; 441-451
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Introduction to molecular biology of influenza a viruses
Autorzy:
Szewczyk, Bogusław
Bieńkowska-Szewczyk, Krystyna
Król, Ewelina
Powiązania:
https://bibliotekanauki.pl/articles/1039236.pdf
Data publikacji:
2014
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
Orthomyxoviridae
influenza A virus
virion structure
genome
entry
release
new polypeptides
Opis:
This minireview presents an overview of current knowledge on virion structure, genome organization and basic events in the development of influenza A virus. The processes of entry, transcription/replication and viral release are described. In this context, the roles of viral proteins (including recently discovered minor polypeptides) in the subsequent stages of viral development are also discussed.
Źródło:
Acta Biochimica Polonica; 2014, 61, 3; 397-401
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Electrochemical biosensors for detection of avian influenza virus - current status and future trends
Autorzy:
Grabowska, Iwona
Malecka, Kamila
Jarocka, Urszula
Radecki, Jerzy
Radecka, Hanna
Powiązania:
https://bibliotekanauki.pl/articles/1039249.pdf
Data publikacji:
2014
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
electrochemical biosensors
genosensors
immunosensors
electrochemical detection
avian influenza virus
Opis:
Electrochemical biosensors have emerged as reliable analytical devices suitable for pathogen detection. Low cost, small sample requirement and possibility of miniaturization justifies their increasing development. Thus, we report in this review on the state of the art of avian influenza virus detection with genosensors and immunosensors working by an electrochemical mode. Their working principles focusing on the physical properties of the transducer, the immobilization chemistry, as well as new trends including incorporation of nanoparticles will be presented. Then, we critically review the detection of avian influenza virus in the complex matrices that use electrochemical biosensors and compare them with traditionally applied methods such as ELISA or Western blot.
Źródło:
Acta Biochimica Polonica; 2014, 61, 3; 471-478
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Detection of the influenza virus yesterday and now
Autorzy:
Woźniak-Kosek, Agnieszka
Kempińska-Mirosławska, Bogumiła
Hoser, Grażyna
Powiązania:
https://bibliotekanauki.pl/articles/1039248.pdf
Data publikacji:
2014
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
influenza
virus
detection method
diagnostics
PCR
viral respiratory tract infection
Opis:
Demographic changes and the development of transportation contribute to the rapid spread of influenza. Before an idea of a 'person to person' spread appeared, divergent theories were developed to explain influenza epidemics in the past. Intensified virological and serological tests became possible after isolation of the human influenza virus in 1933. The first influenza virus detection methods were based on its isolation in egg embryos or cell lines and on demonstration of the presence of the viral antigens. Molecular biology techniques associated with amplification of RNA improved the quality of tests as well as sensitivity of influenza virus detection in clinical samples. It became possible to detect mixed infections caused by influenza types A and B and to identify the strain of the virus. Development of reliable diagnostic methods enabled fast diagnosis of influenza which is important for choosing an appropriate medical treatment.
Źródło:
Acta Biochimica Polonica; 2014, 61, 3; 465-470
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Detection and differentiation of Newcastle disease virus and influenza virus by using duplex real-time PCR
Autorzy:
Nidzworski, Dawid
Wasilewska, Edyta
Smietanka, Krzysztof
Szewczyk, Bogusław
Minta, Zenon
Powiązania:
https://bibliotekanauki.pl/articles/1039554.pdf
Data publikacji:
2013
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
Newcastle disease virus
influenza virus
detection
differentiation
real-time PCR
duplex
Opis:
Newcastle disease virus (NDV), member of the Paramyxoviridae family and avian influenza virus (AIV), member of the Orthomyxoviridae family, are two main avian pathogens causing serious economic problems in poultry health. Both are enveloped, single-stranded, negative-sense RNA viruses and cause similar symptoms, ranging from sub-clinical infections to severe diseases, including decrease in egg production, acute respiratory syndrome, and high mortality. Similar symptoms hinder the differentiation of infection with the two viruses by standard veterinary procedures like clinical examination or necropsy. To overcome this problem, we have developed a new duplex real-time PCR assay for the detection and differentiation of these two viruses. Eighteen NDV strains, fourteen AIV strains, and twelve other (negative control) strains viruses were isolated from allantoic fluids of specific pathogen-free (SPF), embryonated eggs. Four-weeks-old SPF chickens were co-infected with both viruses (NDV - LaSota and AIV - H7N1). Swabs from cloaca and trachea were collected and examined. The results obtained in this study show that by using duplex real-time PCR, it was possible to detect and distinguish both viruses within less than three hours and with high sensitivity, even in case a bird was co-infected. Additionally, the results show the applicability of the real-time PCR assay in laboratory practice for the identification and differentiation of Newcastle disease and influenza A viruses in birds.
Źródło:
Acta Biochimica Polonica; 2013, 60, 3; 475-480
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Choroby świń wywoływane przez cirkowirusy oraz grypa świń w świetle danych 11. Sympozjum Europejskiego Stowarzyszenia Zarządzania Zdrowiem Świń
Swine diseases caused by circoviruses and swine influenza according to data from the 11th European Symposium of Porcine Health Management (ESPHM) in Utrecht
Autorzy:
Turlewicz-Podbielska, Hanna
Pomorska-Mol, Małgorzata
Powiązania:
https://bibliotekanauki.pl/articles/21375470.pdf
Data publikacji:
2019
Wydawca:
Krajowa Izba Lekarsko-Weterynaryjna
Tematy:
trzoda chlewna
choroby wirusowe
cirkowiroza
wirus PCV-2
genotyp
genotypowanie
siewstwo wirusow
wiremia
konferencje
Europejskie Stowarzyszenie Zarządzania Zdrowiem Trzody Chlewnej
Utrecht konferencja
choroby zwierząt
influenza świń
wirus influenzy świń
monitoring chorób
porcine circoviruses
swine influenza virus
11 ESPHM Congress
Opis:
The aim of this article was to present selected papers regarding circovirus infections in swine and also swine influenza, raised during the 11th ESPHM in Utrecht. Issues connected with circovirus-related diseases focus on studies of virus genotypes distribution and determination of the dominant PCV2 genotype in different regions of Europe. Also the prevalence of PCV2 and PCV3, the frequency of co-infection with both genotypes and PCV3 infection related gastrointestinal and respiratory symptoms in swine in European countries, were presented and discussed. These works also discussed the possible interaction between PCV2 and porcine parvovirus PPV4, assessed the pressure of PCV2 infection in pigs of different age and the impact of vaccination protocols on virus excretion. There were studies presented on the differences of virus circulation in vaccinated and unvaccinated animals. Also clinical presentation of infections with different PCV2 strains was described. Much attention was paid to assessment of oral fluid examination in diagnostic procedure. Reports regarding swine influenza have focused on the analysis of various diagnostic methods, the assessment of influenza A virus (IAV), its prevalence in piglets in the early and late nursery period and the analysis of IAV occurrence over the seasons. The diversity of influenza A viruses obtained from outbreaks and samples collected during epizootic monitoring in Spain and Portugal was also discussed, as well as the first case of the H1N1 pandemic subtype in a herd of pigs in Belgium.
Źródło:
Życie Weterynaryjne; 2019, 94, 12
0137-6810
Pojawia się w:
Życie Weterynaryjne
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Characterization of mAb6-9-1 monoclonal antibody against hemagglutinin of avian influenza virus H5N1 and its engineered derivative, single-chain variable fragment antibody
Autorzy:
Sawicka, Róża
Siedlecki, Paweł
Kalenik, Barbara
Radomski, Jan
Sączyńska, Violetta
Porębska, Anna
Szewczyk, Bogusław
Sirko, Agnieszka
Góra-Sochacka, Anna
Powiązania:
https://bibliotekanauki.pl/articles/1038689.pdf
Data publikacji:
2017
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
influenza virus
monoclonal antibody
scFv
hemagglutinin
antigenic epitope
Opis:
Hemagglutinin (HA), as a major surface antigen of influenza virus, is widely used as a target for production of neutralizing antibodies. Monoclonal antibody, mAb6-9-1, directed against HA of highly pathogenic avian influenza virus A/swan/Poland/305-135V08/2006(H5N1) was purified from mouse hybridoma cells culture and characterized. The antigenic specificity of mAb6-9-1 was verified by testing its cross-reactivity with several variants of HA. The mimotopes recognized by mAb6-9-1 were selected from two types of phage display peptide libraries. The comparative structural model of the HA variant used for antibody generation was developed to further facilitate epitope mapping. Based on the sequences of the affinity- selected polypeptides and the structural model of HA the epitope was located to the region near the receptor binding site (RBS). Such localization of the epitope recognized by mAb6-9-1 is in concordance with its moderate hemagglutination inhibiting activity and its antigenic specificity. Additionally, total RNA isolated from the hybridoma cell line secreting mAb6-9-1 was used for obtaining two variants of cDNA encoding recombinant single-chain variable fragment (scFv) antibody. To ensure high production level and solubility in bacterial expression system, the scFv fragments were produced as chimeric proteins in fusion with thioredoxin or displayed on a phage surface after cloning into the phagemid vector. Specificity and affinity of the recombinant soluble and phage-bound scFv were assayed by suitable variants of ELISA test. The observed differences in specificity were discussed.
Źródło:
Acta Biochimica Polonica; 2017, 64, 1; 85-92
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
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